pentoxifylline has been researched along with Cerebral Malaria in 8 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifty-two adult patients with cerebral malaria were randomly categorized into two groups to receive either quinine dihydrochloride (Qn) alone or a combination of Qn and pentoxifylline (Px)." | 9.10 | Pentoxifylline adjunct improves prognosis of human cerebral malaria in adults. ( Das, BK; Manish, R; Mishra, S; Padhi, PK; Ravindran, B; Sahoo, PK; Tripathy, R, 2003) |
| "In an open, randomized, controlled therapeutic trial, 56 children with cerebral malaria (CM) were randomly assigned to receive standard quinine regimen with or without pentoxifylline (10 mg/kg/day by continuous intravenous infusion)." | 9.08 | Pentoxifylline as a supportive agent in the treatment of cerebral malaria in children. ( Bassetti, D; Bonora, S; Cassatella, M; Di Perri, G; Di Perri, IG; Dusi, S; Hennig, C; Micciolo, R; Monteiro, GB; Vento, S, 1995) |
| "Pentoxifylline (PTX) affects many processes that may contribute to the pathogenesis of severe malaria and it has been shown to reduce the duration of coma in children with cerebral malaria." | 7.76 | Pentoxifylline as an adjunct therapy in children with cerebral malaria. ( Kivaya, E; Köhler, C; Kokwaro, G; Kremsner, PG; Lell, B; Mithwani, S; Newton, CR; Olola, CH; Taylor, TE; Wamola, B; Wypij, D, 2010) |
| "The effect of pentoxifylline, a phosphodiesterase inhibitor, was investigated on the development of cerebral malaria in Plasmodium berghei K 173 infected C57/B16 mice." | 7.68 | Selective damage of hippocampal neurons in murine cerebral malaria prevented by pentoxifylline. ( Bienzle, U; Eling, WM; Kremsner, PG; Neifer, S; Stoltenburg-Didinger, G, 1993) |
| "Fifty-two adult patients with cerebral malaria were randomly categorized into two groups to receive either quinine dihydrochloride (Qn) alone or a combination of Qn and pentoxifylline (Px)." | 5.10 | Pentoxifylline adjunct improves prognosis of human cerebral malaria in adults. ( Das, BK; Manish, R; Mishra, S; Padhi, PK; Ravindran, B; Sahoo, PK; Tripathy, R, 2003) |
| "In an open, randomized, controlled therapeutic trial, 56 children with cerebral malaria (CM) were randomly assigned to receive standard quinine regimen with or without pentoxifylline (10 mg/kg/day by continuous intravenous infusion)." | 5.08 | Pentoxifylline as a supportive agent in the treatment of cerebral malaria in children. ( Bassetti, D; Bonora, S; Cassatella, M; Di Perri, G; Di Perri, IG; Dusi, S; Hennig, C; Micciolo, R; Monteiro, GB; Vento, S, 1995) |
| "Pentoxifylline (PTX) affects many processes that may contribute to the pathogenesis of severe malaria and it has been shown to reduce the duration of coma in children with cerebral malaria." | 3.76 | Pentoxifylline as an adjunct therapy in children with cerebral malaria. ( Kivaya, E; Köhler, C; Kokwaro, G; Kremsner, PG; Lell, B; Mithwani, S; Newton, CR; Olola, CH; Taylor, TE; Wamola, B; Wypij, D, 2010) |
| "The effect of pentoxifylline, a phosphodiesterase inhibitor, was investigated on the development of cerebral malaria in Plasmodium berghei K 173 infected C57/B16 mice." | 3.68 | Selective damage of hippocampal neurons in murine cerebral malaria prevented by pentoxifylline. ( Bienzle, U; Eling, WM; Kremsner, PG; Neifer, S; Stoltenburg-Didinger, G, 1993) |
| "The clinical picture of cerebral malaria may persist or even become worse in spite of the clearance of parasites from blood." | 2.43 | Adjuvant therapy in cerebral malaria. ( Mishra, SK; Mohanty, S; Patel, DK; Pati, SS, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lell, B | 1 |
| Köhler, C | 1 |
| Wamola, B | 1 |
| Olola, CH | 1 |
| Kivaya, E | 1 |
| Kokwaro, G | 1 |
| Wypij, D | 1 |
| Mithwani, S | 1 |
| Taylor, TE | 1 |
| Kremsner, PG | 2 |
| Newton, CR | 1 |
| Das, BK | 1 |
| Mishra, S | 1 |
| Padhi, PK | 1 |
| Manish, R | 1 |
| Tripathy, R | 1 |
| Sahoo, PK | 1 |
| Ravindran, B | 1 |
| Enwere, G | 1 |
| Mohanty, S | 1 |
| Patel, DK | 1 |
| Pati, SS | 1 |
| Mishra, SK | 1 |
| Di Perri, G | 1 |
| Di Perri, IG | 1 |
| Monteiro, GB | 1 |
| Bonora, S | 1 |
| Hennig, C | 1 |
| Cassatella, M | 1 |
| Micciolo, R | 1 |
| Vento, S | 1 |
| Dusi, S | 1 |
| Bassetti, D | 1 |
| Landau, Z | 1 |
| Attali, M | 1 |
| Moling, O | 1 |
| Mian, P | 1 |
| Stoltenburg-Didinger, G | 1 |
| Neifer, S | 1 |
| Bienzle, U | 1 |
| Eling, WM | 1 |
2 reviews available for pentoxifylline and Cerebral Malaria
| Article | Year |
|---|---|
A review of the quality of randomized clinical trials of adjunctive therapy for the treatment of cerebral malaria.
Topics: Anticonvulsants; Deferoxamine; Dexamethasone; Double-Blind Method; Enzyme Inhibitors; Humans; Malari | 2005 |
Adjuvant therapy in cerebral malaria.
Topics: Adrenal Cortex Hormones; Antimalarials; Blood-Brain Barrier; Chemotherapy, Adjuvant; Deferoxamine; H | 2006 |
2 trials available for pentoxifylline and Cerebral Malaria
| Article | Year |
|---|---|
Pentoxifylline adjunct improves prognosis of human cerebral malaria in adults.
Topics: Adult; Antimalarials; Drug Therapy, Combination; Female; Humans; Malaria, Cerebral; Male; Middle Age | 2003 |
Pentoxifylline as a supportive agent in the treatment of cerebral malaria in children.
Topics: Adolescent; Burundi; Child; Child, Preschool; Coma; Drug Therapy, Combination; Female; Humans; Malar | 1995 |
4 other studies available for pentoxifylline and Cerebral Malaria
| Article | Year |
|---|---|
Pentoxifylline as an adjunct therapy in children with cerebral malaria.
Topics: Antimalarials; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Infusions | 2010 |
Use of pentoxifylline in the treatment of cerebral malaria.
Topics: Aged; Humans; Malaria, Cerebral; Male; Pentoxifylline; Tumor Necrosis Factor-alpha | 1993 |
Use of pentoxifylline in the treatment of cerebral malaria.
Topics: Humans; Malaria, Cerebral; Pentoxifylline | 1994 |
Selective damage of hippocampal neurons in murine cerebral malaria prevented by pentoxifylline.
Topics: Animals; Female; Hemorrhage; Hippocampus; Malaria, Cerebral; Mice; Mice, Inbred BALB C; Mice, Inbred | 1993 |