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pentoxifylline and Cardiovascular Stroke

pentoxifylline has been researched along with Cardiovascular Stroke in 17 studies

Research Excerpts

ExcerptRelevanceReference
"To determine the effect of cilostazol on initial and absolute claudication distances, mortality and vascular events in patients with stable intermittent claudication."9.12Cilostazol for intermittent claudication. ( Brown, T; Cleanthis, M; Forster, RB; Mikhailidis, DP; Stansby, G; Stewart, M, 2021)
"To determine the effect of cilostazol (an antiplatelet treatment) on improving initial and absolute claudication distances, and in reducing mortality and vascular events in patients with stable intermittent claudication."8.90Cilostazol for intermittent claudication. ( Bedenis, R; Cleanthis, M; Mikhailidis, DP; Robless, P; Stansby, G; Stewart, M, 2014)
"We have observed that, after myocardial infarction (MI), rats display apoptosis in the limbic system that can be prevented by pentoxifylline (PTX), a proinflammatory cytokine inhibitor."7.77Pretreatment with pentoxifylline has antidepressant-like effects in a rat model of acute myocardial infarction. ( Bah, TM; Godbout, R; Kaloustian, S; Rousseau, G, 2011)
" The effect of the haemorrheological agent pentoxifylline was investigated in a canine model of acute myocardial infarction, induced by occlusion of the left anterior descending coronary for 6 h."7.67Pentoxifylline does not reduce infarct size in a canine model of acute myocardial infarction. ( Campbell, CA; Clavenna, CF; Kloner, RA; Wynne, J, 1988)
"Pentoxifylline is a methylxanthine derivative with known anti-inflammatory, antioxidant, vasodilator, and rheological properties which can be a promising agent in preventing reperfusion injury."7.30Evaluating the role of intravenous pentoxifylline administration on primary percutaneous coronary intervention success rate in patients with ST-elevation myocardial infarction (PENTOS-PCI). ( Aghakouchakzadeh, M; Amoli, AI; Hosseini, SH; Jalali, A; Jenab, Y; Kakavand, H; Naderian, M; Pourhosseini, H; Saadatagah, S; Sadri, F; Salarifar, M; Talasaz, AH, 2023)
"Pentoxifylline has more beneficial potencies in reducing adverse events after coronary artery bypass graft using cardiopulmonary bypass, than what are known."6.80Preoperative oral pentoxifylline in case of coronary artery bypass grafting with left ventricular dysfunction (ejection fraction equal to/less than 30%). ( Abbasi, K; Bina, P; Boroumand, MA; Fehri, A; Karimi, AA; Mansourian, S, 2015)
"To determine the effect of cilostazol on initial and absolute claudication distances, mortality and vascular events in patients with stable intermittent claudication."5.12Cilostazol for intermittent claudication. ( Brown, T; Cleanthis, M; Forster, RB; Mikhailidis, DP; Stansby, G; Stewart, M, 2021)
"To determine the effect of cilostazol (an antiplatelet treatment) on improving initial and absolute claudication distances, and in reducing mortality and vascular events in patients with stable intermittent claudication."4.90Cilostazol for intermittent claudication. ( Bedenis, R; Cleanthis, M; Mikhailidis, DP; Robless, P; Stansby, G; Stewart, M, 2014)
" We hypothesized that inhibition of neuroinflammation by the PIC synthesis inhibitor, pentoxifylline (PTX) would prevent depression-like behaviors induced by heart failure (HF) post-MI in OVX female rats."3.91Role of Myocardial Infarction-Induced Neuroinflammation for Depression-Like Behavior and Heart Failure in Ovariectomized Female Rats. ( Ahmad, M; Lagace, D; Leenen, FHH; Najjar, F, 2019)
"We have observed that, after myocardial infarction (MI), rats display apoptosis in the limbic system that can be prevented by pentoxifylline (PTX), a proinflammatory cytokine inhibitor."3.77Pretreatment with pentoxifylline has antidepressant-like effects in a rat model of acute myocardial infarction. ( Bah, TM; Godbout, R; Kaloustian, S; Rousseau, G, 2011)
" The effect of the haemorrheological agent pentoxifylline was investigated in a canine model of acute myocardial infarction, induced by occlusion of the left anterior descending coronary for 6 h."3.67Pentoxifylline does not reduce infarct size in a canine model of acute myocardial infarction. ( Campbell, CA; Clavenna, CF; Kloner, RA; Wynne, J, 1988)
"Pentoxifylline is a methylxanthine derivative with known anti-inflammatory, antioxidant, vasodilator, and rheological properties which can be a promising agent in preventing reperfusion injury."3.30Evaluating the role of intravenous pentoxifylline administration on primary percutaneous coronary intervention success rate in patients with ST-elevation myocardial infarction (PENTOS-PCI). ( Aghakouchakzadeh, M; Amoli, AI; Hosseini, SH; Jalali, A; Jenab, Y; Kakavand, H; Naderian, M; Pourhosseini, H; Saadatagah, S; Sadri, F; Salarifar, M; Talasaz, AH, 2023)
"Pentoxifylline has more beneficial potencies in reducing adverse events after coronary artery bypass graft using cardiopulmonary bypass, than what are known."2.80Preoperative oral pentoxifylline in case of coronary artery bypass grafting with left ventricular dysfunction (ejection fraction equal to/less than 30%). ( Abbasi, K; Bina, P; Boroumand, MA; Fehri, A; Karimi, AA; Mansourian, S, 2015)
"Myocardial infarction was produced in anesthetized rats by a 40-minute occlusion of the left anterior descending coronary artery followed by 72 hours of reperfusion."1.33Apoptosis detected in the amygdala following myocardial infarction in the rat. ( Boucher, M; Godbout, R; Kaloustian, S; Nim, S; Rousseau, G; Wann, BP, 2006)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19904 (23.53)18.7374
1990's1 (5.88)18.2507
2000's3 (17.65)29.6817
2010's6 (35.29)24.3611
2020's3 (17.65)2.80

Authors

AuthorsStudies
Kakavand, H1
Saadatagah, S1
Naderian, M1
Aghakouchakzadeh, M1
Jalali, A1
Sadri, F1
Amoli, AI1
Hosseini, SH1
Jenab, Y1
Pourhosseini, H1
Salarifar, M1
Talasaz, AH1
Elseweidy, MM1
Ali, SI1
Shaheen, MA1
Abdelghafour, AM1
Hammad, SK1
Brown, T1
Forster, RB1
Cleanthis, M2
Mikhailidis, DP2
Stansby, G2
Stewart, M2
Namdar, H1
Zohori, R1
Aslanabadi, N2
Entezari-Maleki, T2
Najjar, F1
Ahmad, M1
Lagace, D1
Leenen, FHH1
Bedenis, R1
Robless, P1
Shirzadi, HR1
Asghari-Soufi, H1
Dousti, S1
Ghaffari, S1
Sohrabi, B1
Mashayekhi, SO1
Hamishehkar, H1
Mansourian, S1
Bina, P1
Fehri, A1
Karimi, AA1
Boroumand, MA1
Abbasi, K1
Bah, TM1
Kaloustian, S2
Rousseau, G2
Godbout, R2
Francis, J1
Chu, Y1
Johnson, AK1
Weiss, RM1
Felder, RB1
Wann, BP1
Boucher, M1
Nim, S1
Tulsyan, N1
Ouriel, K1
Kashyap, VS1
Lechleitner, P1
Genser, N1
Mair, J1
Maier, J1
Herold, M1
Beimpold, H1
Föger, B1
Dienstl, F1
Puschendorf, B1
Tilg, H1
Breddin, HK1
Manrique, RV1
Manrique, V1
Campbell, CA1
Clavenna, CF1
Wynne, J1
Kloner, RA1
Badalian, GO1
Episkoposian, NG1
Amatuni, GV1

Reviews

4 reviews available for pentoxifylline and Cardiovascular Stroke

ArticleYear
Cilostazol for intermittent claudication.
    The Cochrane database of systematic reviews, 2021, 06-30, Volume: 6

    Topics: Aged; Bias; Cilostazol; Humans; Intermittent Claudication; Middle Aged; Myocardial Infarction; Pento

2021
Cilostazol for intermittent claudication.
    The Cochrane database of systematic reviews, 2014, Oct-31, Issue:10

    Topics: Aged; Cilostazol; Humans; Intermittent Claudication; Middle Aged; Myocardial Infarction; Pentoxifyll

2014
Emerging drugs in peripheral arterial disease.
    Expert opinion on emerging drugs, 2006, Volume: 11, Issue:1

    Topics: Administration, Oral; Anticoagulants; Arterial Occlusive Diseases; Arteries; Aspirin; Clopidogrel; D

2006
Current perspectives in the antiplatelet therapy of thrombotic disorders.
    Seminars in thrombosis and hemostasis, 1989, Volume: 15, Issue:2

    Topics: Angina, Unstable; Aspirin; Clinical Trials as Topic; Coronary Disease; Coronary Thrombosis; Humans;

1989

Trials

6 trials available for pentoxifylline and Cardiovascular Stroke

ArticleYear
Evaluating the role of intravenous pentoxifylline administration on primary percutaneous coronary intervention success rate in patients with ST-elevation myocardial infarction (PENTOS-PCI).
    Naunyn-Schmiedeberg's archives of pharmacology, 2023, Volume: 396, Issue:3

    Topics: Administration, Intravenous; Antioxidants; Humans; Infusions, Intravenous; Myocardial Infarction; Pe

2023
Effect of Pentoxifylline in Ameliorating Myocardial Injury in Patients With Myocardial Infarction Undergoing Thrombolytic Therapy: A Pilot Randomized Clinical Trial.
    Journal of clinical pharmacology, 2017, Volume: 57, Issue:10

    Topics: Aged; Biomarkers; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Myocardial Infarction; Pen

2017
A pilot randomized trial of pentoxifylline for the reduction of periprocedural myocardial injury in patients undergoing elective percutaneous coronary intervention.
    European journal of clinical pharmacology, 2015, Volume: 71, Issue:2

    Topics: Aged; Creatine Kinase, MB Form; Elective Surgical Procedures; Female; Humans; Male; Middle Aged; Myo

2015
Preoperative oral pentoxifylline in case of coronary artery bypass grafting with left ventricular dysfunction (ejection fraction equal to/less than 30%).
    Anatolian journal of cardiology, 2015, Volume: 15, Issue:12

    Topics: Administration, Oral; Aged; Coronary Artery Bypass; Female; Humans; Male; Middle Aged; Myocardial In

2015
Pentoxifylline influences acute-phase response in acute myocardial infarction.
    The Clinical investigator, 1992, Volume: 70, Issue:9

    Topics: Acute-Phase Reaction; Adult; Aged; Aged, 80 and over; C-Reactive Protein; Female; Humans; Male; Midd

1992
Current perspectives in the antiplatelet therapy of thrombotic disorders.
    Seminars in thrombosis and hemostasis, 1989, Volume: 15, Issue:2

    Topics: Angina, Unstable; Aspirin; Clinical Trials as Topic; Coronary Disease; Coronary Thrombosis; Humans;

1989

Other Studies

8 other studies available for pentoxifylline and Cardiovascular Stroke

ArticleYear
Vanillin and pentoxifylline ameliorate isoproterenol-induced myocardial injury in rats
    Food & function, 2023, Apr-03, Volume: 14, Issue:7

    Topics: Animals; Inflammation; Isoproterenol; Myocardial Infarction; Myocardium; Oxidative Stress; Pentoxify

2023
Role of Myocardial Infarction-Induced Neuroinflammation for Depression-Like Behavior and Heart Failure in Ovariectomized Female Rats.
    Neuroscience, 2019, 09-01, Volume: 415

    Topics: Animals; Behavior Rating Scale; Brain-Derived Neurotrophic Factor; Cytokines; Depression; Disease Mo

2019
Pretreatment with pentoxifylline has antidepressant-like effects in a rat model of acute myocardial infarction.
    Behavioural pharmacology, 2011, Volume: 22, Issue:8

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Choice Behavior; Depressive Disorder; Disease Mode

2011
Acute myocardial infarction induces hypothalamic cytokine synthesis.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 286, Issue:6

    Topics: Animals; Gene Expression; Heart Failure; Hypothalamo-Hypophyseal System; Male; Myocardial Infarction

2004
Apoptosis detected in the amygdala following myocardial infarction in the rat.
    Biological psychiatry, 2006, Mar-01, Volume: 59, Issue:5

    Topics: Amygdala; Animals; Apoptosis; Cerebellum; Cytokines; Depressive Disorder, Major; Disease Models, Ani

2006
Platelet resistance to prostacyclin. Enhancement of the antiaggregatory effect of prostacyclin by pentoxifylline.
    Angiology, 1987, Volume: 38, Issue:2 Pt 1

    Topics: Adult; Aged; Arterial Occlusive Diseases; Arteriosclerosis; Blood Platelets; Cyclic AMP; Drug Resist

1987
Pentoxifylline does not reduce infarct size in a canine model of acute myocardial infarction.
    British journal of pharmacology, 1988, Volume: 93, Issue:3

    Topics: Animals; Blood Pressure; Coronary Disease; Coronary Vessels; Disease Models, Animal; Dogs; Heart Rat

1988
[Effect of fructose-1,6-diphosphate and trental on the erythrocyte aggregating capacity in ischemic heart disease].
    Terapevticheskii arkhiv, 1987, Volume: 59, Issue:7

    Topics: Adult; Aged; Alcian Blue; Angina Pectoris; Coronary Disease; Dose-Response Relationship, Drug; Drug

1987