pentoxifylline has been researched along with Cardiomegaly in 7 studies
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Moreover, we put in light a TNF-α-independent beneficial effect of pentoxifylline in the VEETKO mice suggesting a therapeutic potential for pentoxifylline in a subpopulation of heart failure patients at higher risk." | 3.80 | Vascular endothelium derived endothelin-1 is required for normal heart function after chronic pressure overload in mice. ( Emoto, N; Heiden, S; Masuda, S; Nakayama, K; Vignon-Zellweger, N; Yagi, K; Yanagisawa, M, 2014) |
| "These findings suggest that in chronic cardiac hypertrophy, contractile responses to phosphodiesterase inhibitors may be preserved despite marked reductions in inotropic responses to beta-adrenoceptor agonists." | 1.33 | Inotropic responses to phosphodiesterase inhibitors in cardiac hypertrophy in rats. ( Norton, G; Osadchii, O; Woodiwiss, A, 2005) |
| " As chronic administration of a beta-adrenoreceptor (beta-AR) agonist mediates the premature onset of cardiac remodeling without myocyte necrosis or myocardial dysfunction in LVH, we suggest that beta-AR activation is critical in promoting the transition from compensated LVH to cardiac dilatation." | 1.33 | Phosphodiesterase inhibition promotes the transition from compensated hypertrophy to cardiac dilatation in rats. ( Anamourlis, C; Badenhorst, D; Correia, R; Gibbs, M; Norton, GR; Osadchii, O; Veliotes, D; Woodiwiss, AJ, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Heiden, S | 1 |
| Vignon-Zellweger, N | 1 |
| Masuda, S | 1 |
| Yagi, K | 1 |
| Nakayama, K | 1 |
| Yanagisawa, M | 1 |
| Emoto, N | 1 |
| Song, XA | 1 |
| Jia, LL | 1 |
| Cui, W | 1 |
| Zhang, M | 1 |
| Chen, W | 1 |
| Yuan, ZY | 1 |
| Guo, J | 1 |
| Li, HH | 1 |
| Zhu, GQ | 1 |
| Liu, H | 1 |
| Kang, YM | 1 |
| Zhang, X | 1 |
| Meng, F | 1 |
| Song, J | 1 |
| Zhang, L | 1 |
| Wang, J | 1 |
| Li, D | 1 |
| Li, L | 1 |
| Dong, P | 1 |
| Yang, B | 1 |
| Chen, Y | 1 |
| Dhiman, S | 1 |
| Mishra, N | 1 |
| Sharma, S | 1 |
| Osadchii, O | 2 |
| Norton, G | 1 |
| Woodiwiss, A | 1 |
| Anamourlis, C | 1 |
| Badenhorst, D | 1 |
| Gibbs, M | 1 |
| Correia, R | 1 |
| Veliotes, D | 1 |
| Norton, GR | 1 |
| Woodiwiss, AJ | 1 |
| Heublein, B | 1 |
| Franz, N | 1 |
| Modersohn, D | 1 |
| Linss, G | 1 |
| Lange, T | 1 |
| Specht, FK | 1 |
| Heublein-Balint, EG | 1 |
7 other studies available for pentoxifylline and Cardiomegaly
| Article | Year |
|---|---|
Vascular endothelium derived endothelin-1 is required for normal heart function after chronic pressure overload in mice.
Topics: Animals; Aorta; Apoptosis; Blood Pressure; Cardiomegaly; Echocardiography; Endothelin-1; Endothelium | 2014 |
Inhibition of TNF-α in hypothalamic paraventricular nucleus attenuates hypertension and cardiac hypertrophy by inhibiting neurohormonal excitation in spontaneously hypertensive rats.
Topics: Animals; Cardiomegaly; Hypertension; Male; Neurotransmitter Agents; Paraventricular Hypothalamic Nuc | 2014 |
Pentoxifylline Ameliorates Cardiac Fibrosis, Pathological Hypertrophy, and Cardiac Dysfunction in Angiotensin II-induced Hypertensive Rats.
Topics: Angiotensin II; Animals; Cardiomegaly; Fibrosis; Hypertension; Inflammation Mediators; Male; Pentoxi | 2016 |
Development of PEGylated solid lipid nanoparticles of pentoxifylline for their beneficial pharmacological potential in pathological cardiac hypertrophy.
Topics: Animals; Cardiomegaly; Disease Models, Animal; Lipids; Male; Nanoparticles; Pentoxifylline; Polyethy | 2016 |
Inotropic responses to phosphodiesterase inhibitors in cardiac hypertrophy in rats.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amrinone; Animals; Blood Pressure; Cardiomegaly; Cardiotonic | 2005 |
Phosphodiesterase inhibition promotes the transition from compensated hypertrophy to cardiac dilatation in rats.
Topics: Animals; Blood Pressure; Cardiomegaly; Collagen; Cyclic AMP; Heart; Myocardial Contraction; Organ Si | 2006 |
[Effects of pentoxifylline on diastolic heart function in patients with angina pectoris and an increased left ventricular wall mass].
Topics: Adult; Angina Pectoris; Cardiomegaly; Diastole; Female; Heart Ventricles; Hemodynamics; Humans; Info | 1988 |