pentoxifylline has been researched along with Cardiac Failure in 27 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pentoxifylline possess antiinflammatory and rheological properties and has been tested in heart failure (HF)." | 8.90 | Pentoxifylline in heart failure: a meta-analysis of clinical trials. ( Champion, S; Cherié, G; Lapidus, N; Oliary, J; Solal, AC; Spagnoli, V, 2014) |
| "Recent trials have indicated a beneficial effect of pentoxifylline on measures of inflammation and markers of cardiac dysfunction in people with heart failure." | 8.82 | Pentoxifylline for heart failure: a systematic review. ( Batchelder, K; Mayosi, BM, 2005) |
| "21 patients with symptoms of chronic congestive heart failure, NYHA classes II-IV, were treated with digoxin and furosemide for at least 14 days." | 7.68 | [The effect of combined treatment in chronic congestive heart failure with digoxin, furosemide and pentoxifylline upon blood viscosity]. ( Kochmański, M; Zochowski, RJ, 1990) |
| "Pentoxifylline, a xanthine derivative with vasoactive and hemorheologic properties, was studied in regard to effect on central hemodynamics in ten patients with congestive heart failure due to aortic or mitral valve disease, mainly in NYHA group III or IV." | 7.67 | Effects of pentoxifylline on central hemodynamics in patients with congestive heart failure. ( Ekeström, S; Liljeqvist, L; Nordhus, O, 1986) |
| "Pentoxifylline possess antiinflammatory and rheological properties and has been tested in heart failure (HF)." | 4.90 | Pentoxifylline in heart failure: a meta-analysis of clinical trials. ( Champion, S; Cherié, G; Lapidus, N; Oliary, J; Solal, AC; Spagnoli, V, 2014) |
| "Recent trials have indicated a beneficial effect of pentoxifylline on measures of inflammation and markers of cardiac dysfunction in people with heart failure." | 4.82 | Pentoxifylline for heart failure: a systematic review. ( Batchelder, K; Mayosi, BM, 2005) |
| " We hypothesized that inhibition of neuroinflammation by the PIC synthesis inhibitor, pentoxifylline (PTX) would prevent depression-like behaviors induced by heart failure (HF) post-MI in OVX female rats." | 3.91 | Role of Myocardial Infarction-Induced Neuroinflammation for Depression-Like Behavior and Heart Failure in Ovariectomized Female Rats. ( Ahmad, M; Lagace, D; Leenen, FHH; Najjar, F, 2019) |
| " Moreover, we put in light a TNF-α-independent beneficial effect of pentoxifylline in the VEETKO mice suggesting a therapeutic potential for pentoxifylline in a subpopulation of heart failure patients at higher risk." | 3.80 | Vascular endothelium derived endothelin-1 is required for normal heart function after chronic pressure overload in mice. ( Emoto, N; Heiden, S; Masuda, S; Nakayama, K; Vignon-Zellweger, N; Yagi, K; Yanagisawa, M, 2014) |
| "21 patients with symptoms of chronic congestive heart failure, NYHA classes II-IV, were treated with digoxin and furosemide for at least 14 days." | 3.68 | [The effect of combined treatment in chronic congestive heart failure with digoxin, furosemide and pentoxifylline upon blood viscosity]. ( Kochmański, M; Zochowski, RJ, 1990) |
| "Pentoxifylline, a xanthine derivative with vasoactive and hemorheologic properties, was studied in regard to effect on central hemodynamics in ten patients with congestive heart failure due to aortic or mitral valve disease, mainly in NYHA group III or IV." | 3.67 | Effects of pentoxifylline on central hemodynamics in patients with congestive heart failure. ( Ekeström, S; Liljeqvist, L; Nordhus, O, 1986) |
| "Heart failure was induced in Sprague-Dawley rats by coronary artery ligation." | 1.35 | Cytokine blockade attenuates sympathoexcitation in heart failure: cross-talk between nNOS, AT-1R and cytokines in the hypothalamic paraventricular nucleus. ( Ebenezer, PJ; Francis, J; Guggilam, A; Haque, M; Kapusta, DR; Patel, KP, 2008) |
| "His disease relapsed without recurrence of the capillary leak." | 1.31 | Systemic capillary leak syndrome preceding plasma cell leukaemia. ( Ghosh, K; Iyer, Y; Jijina, F; Madkaikar, M; Mohanty, D; Pathare, A, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.41) | 18.7374 |
| 1990's | 2 (7.41) | 18.2507 |
| 2000's | 18 (66.67) | 29.6817 |
| 2010's | 5 (18.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Najjar, F | 1 |
| Ahmad, M | 1 |
| Lagace, D | 1 |
| Leenen, FHH | 1 |
| Heiden, S | 1 |
| Vignon-Zellweger, N | 1 |
| Masuda, S | 1 |
| Yagi, K | 1 |
| Nakayama, K | 1 |
| Yanagisawa, M | 1 |
| Emoto, N | 1 |
| Champion, S | 1 |
| Lapidus, N | 1 |
| Cherié, G | 1 |
| Spagnoli, V | 1 |
| Oliary, J | 1 |
| Solal, AC | 1 |
| Mann, DL | 2 |
| Kalantar-Zadeh, K | 1 |
| Anker, SD | 1 |
| Horwich, TB | 1 |
| Fonarow, GC | 1 |
| Guggilam, A | 2 |
| Patel, KP | 1 |
| Haque, M | 1 |
| Ebenezer, PJ | 1 |
| Kapusta, DR | 1 |
| Francis, J | 3 |
| Fu, M | 1 |
| Shaw, SM | 1 |
| Shah, MK | 1 |
| Williams, SG | 1 |
| Fildes, JE | 1 |
| Kang, YM | 2 |
| He, RL | 1 |
| Yang, LM | 1 |
| Qin, DN | 1 |
| Elks, C | 1 |
| Yan, N | 1 |
| Guo, Z | 1 |
| Silverberg, DS | 1 |
| Wexler, D | 1 |
| Iaina, A | 1 |
| Schwartz, D | 1 |
| Nisi, A | 1 |
| Panfili, M | 1 |
| De Rosa, G | 1 |
| Boffa, G | 1 |
| Groppa, F | 1 |
| Gusella, M | 1 |
| Padrini, R | 1 |
| Staudt, A | 1 |
| Landsberger, M | 1 |
| Staudt, Y | 1 |
| Felix, SB | 1 |
| Nessler, J | 1 |
| Skrzypek, A | 1 |
| Chu, Y | 1 |
| Johnson, AK | 1 |
| Weiss, RM | 2 |
| Felder, RB | 2 |
| Batchelder, K | 1 |
| Mayosi, BM | 1 |
| Aukrust, P | 1 |
| Yndestad, A | 1 |
| Ueland, T | 1 |
| Damås, JK | 1 |
| Gullestad, L | 1 |
| Balakumar, P | 1 |
| Singh, M | 1 |
| Zhang, ZH | 1 |
| Xue, B | 1 |
| Beyreder, J | 1 |
| Koshlia, VI | 1 |
| Maliukova, NG | 1 |
| Marshall, D | 1 |
| Sack, MN | 1 |
| Ghosh, K | 1 |
| Madkaikar, M | 1 |
| Iyer, Y | 1 |
| Pathare, A | 1 |
| Jijina, F | 1 |
| Mohanty, D | 1 |
| Lisman, KA | 1 |
| Stetson, SJ | 1 |
| Koerner, MM | 1 |
| Farmer, JA | 1 |
| Torre-Amione, G | 1 |
| Negrusz-Kawecka, M | 1 |
| Kochmański, M | 1 |
| Zochowski, RJ | 1 |
| Nordhus, O | 1 |
| Ekeström, S | 1 |
| Liljeqvist, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| GutHeart: Targeting Gut Microbiota to Treat Heart Failure[NCT02637167] | Phase 2 | 150 participants (Anticipated) | Interventional | 2016-03-11 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 reviews available for pentoxifylline and Cardiac Failure
| Article | Year |
|---|---|
Pentoxifylline in heart failure: a meta-analysis of clinical trials.
Topics: Cardiovascular Agents; Heart Failure; Humans; Odds Ratio; Pentoxifylline; Randomized Controlled Tria | 2014 |
Innate immunity and the failing heart: the cytokine hypothesis revisited.
Topics: Adaptive Immunity; Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Autoantibodies; Autoim | 2015 |
Nutritional and anti-inflammatory interventions in chronic heart failure.
Topics: Amino Acids; Anorexia; Antioxidants; Appetite Stimulants; Cachexia; Comorbidity; Dietary Supplements | 2008 |
Immunological mechanisms of pentoxifylline in chronic heart failure.
Topics: Chronic Disease; Heart Failure; Humans; Immunologic Factors; Pentoxifylline; Phosphodiesterase Inhib | 2009 |
[Cytokines--causes, players or bystanders in heart failure].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Cardiomyopathy, Dilated; C | 2002 |
Inflammatory mediators and the failing heart: past, present, and the foreseeable future.
Topics: Animals; Antibodies, Monoclonal; Antirheumatic Agents; Clinical Trials as Topic; Cytokines; Disease | 2002 |
[The modern view on the role of inflammatory factors in chronic heart failure and possibilities of pharmacological modification].
Topics: Adrenergic beta-Antagonists; Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory | 2003 |
Pentoxifylline for heart failure: a systematic review.
Topics: Double-Blind Method; Heart Failure; Humans; Pentoxifylline; Prospective Studies; Randomized Controll | 2005 |
Anti-inflammatory trials in chronic heart failure.
Topics: Adult; Aged; Animals; Cytokines; Female; Free Radical Scavengers; Heart Failure; Humans; Immunoglobu | 2006 |
Anti-tumour necrosis factor-alpha therapy in heart failure: future directions.
Topics: Animals; Antibodies, Monoclonal; Etanercept; Heart Failure; Humans; Immunoglobulin G; Infliximab; Pe | 2006 |
Managing heart failure with immunomodulatory agents.
Topics: Adjuvants, Immunologic; Cytokines; Etanercept; Heart Failure; Hematologic Agents; Humans; Immunoglob | 2001 |
[The role of TNF-alpha in the etiopathogenesis of heart failure].
Topics: Cardiomyopathy, Dilated; Etanercept; Heart Failure; Humans; Immunoglobulin G; Immunologic Factors; P | 2002 |
2 trials available for pentoxifylline and Cardiac Failure
| Article | Year |
|---|---|
Pharmacokinetics of pentoxifylline and its main metabolites in patients with different degrees of heart failure following a single dose of a modified-release formulation.
Topics: Adult; Aged; Aged, 80 and over; Delayed-Action Preparations; Female; Heart Failure; Humans; Male; Mi | 2013 |
[Therapy of acute cerebrovascular insufficiency].
Topics: Acute Disease; Arrhythmias, Cardiac; Brain Ischemia; Cerebral Infarction; Double-Blind Method; Femal | 1981 |
13 other studies available for pentoxifylline and Cardiac Failure
| Article | Year |
|---|---|
Role of Myocardial Infarction-Induced Neuroinflammation for Depression-Like Behavior and Heart Failure in Ovariectomized Female Rats.
Topics: Animals; Behavior Rating Scale; Brain-Derived Neurotrophic Factor; Cytokines; Depression; Disease Mo | 2019 |
Vascular endothelium derived endothelin-1 is required for normal heart function after chronic pressure overload in mice.
Topics: Animals; Aorta; Apoptosis; Blood Pressure; Cardiomegaly; Echocardiography; Endothelin-1; Endothelium | 2014 |
Cytokine blockade attenuates sympathoexcitation in heart failure: cross-talk between nNOS, AT-1R and cytokines in the hypothalamic paraventricular nucleus.
Topics: Analysis of Variance; Animals; Blotting, Western; Cytokines; Echocardiography; Enzyme-Linked Immunos | 2008 |
Inflammation in chronic heart failure: what is familiar, what is unfamiliar?
Topics: Anti-Inflammatory Agents; Chronic Disease; Heart Failure; Humans; Inflammation; Pentoxifylline; Tumo | 2009 |
Brain tumour necrosis factor-alpha modulates neurotransmitters in hypothalamic paraventricular nucleus in heart failure.
Topics: Animals; Brain; Cytokines; Etanercept; Heart Failure; Immunoglobulin G; Inflammation Mediators; Kidn | 2009 |
Immunological mechanisms of pentoxifylline in chronic heart failure.
Topics: Anemia; Biomarkers; Chronic Disease; Heart Failure; Hemoglobins; Humans; Immunologic Factors; Pentox | 2009 |
Acute myocardial infarction induces hypothalamic cytokine synthesis.
Topics: Animals; Gene Expression; Heart Failure; Hypothalamo-Hypophyseal System; Male; Myocardial Infarction | 2004 |
Inhibition of brain proinflammatory cytokine synthesis reduces hypothalamic excitation in rats with ischemia-induced heart failure.
Topics: Action Potentials; Adrenocorticotropic Hormone; Angiotensin II; Animals; Anti-Inflammatory Agents; C | 2008 |
[Changes in external respiration due to vasoactive therapy in patients with heart failure].
Topics: Adult; Aged; Female; Heart Failure; Humans; Lung; Male; Middle Aged; Nitroglycerin; Pentoxifylline; | 1995 |
Apoptosis: a pivotal event or an epiphenomenon in the pathophysiology of heart failure?
Topics: Apoptosis; Heart; Heart Failure; Humans; Muscle, Skeletal; Pentoxifylline; Phosphodiesterase Inhibit | 2000 |
Systemic capillary leak syndrome preceding plasma cell leukaemia.
Topics: Adult; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Capillar | 2001 |
[The effect of combined treatment in chronic congestive heart failure with digoxin, furosemide and pentoxifylline upon blood viscosity].
Topics: Adult; Aged; Blood Viscosity; Digoxin; Drug Therapy, Combination; Female; Furosemide; Heart Failure; | 1990 |
Effects of pentoxifylline on central hemodynamics in patients with congestive heart failure.
Topics: Aged; Blood Pressure; Cardiac Output; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged | 1986 |