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pentoxifylline and Carcinoma, Squamous Cell

pentoxifylline has been researched along with Carcinoma, Squamous Cell in 12 studies

Carcinoma, Squamous Cell: A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"The data indicate a beneficial therapeutic effect of pentoxifylline and vitamin E on radiation-induced fibrosis."8.79[The treatment of cutaneous radiation-induced fibrosis with pentoxifylline and vitamin E. An empirical report]. ( Gottlöber, P; Korting, HC; Krähn, G; Peter, RU; Stock, W, 1996)
"The influence of pentoxifylline on radiotoxicity was assessed by colony assay in TP53 wild-type Bell and mutant MeWo melanoma, and in TP53 wild-type 4197 and mutant 4451 squamous cell carcinoma (SCC) cell lines."7.70The role of G2-block abrogation, DNA double-strand break repair and apoptosis in the radiosensitization of melanoma and squamous cell carcinoma cell lines by pentoxifylline. ( Binder, A; Böhm, L; Theron, T; Verheye-Dua, F, 2000)
"Osteoradionecrosis is a complication of head and neck radiotherapy, with a difficult resolution and no well-established treatment."5.43Tissue repair in osteoradionecrosis using pentoxifylline and tocopherol--report of three cases. ( Bohn, JC; Sassi, LM; Schussel, JL; Stramandinoli-Zanicotti, RT, 2016)
"The data indicate a beneficial therapeutic effect of pentoxifylline and vitamin E on radiation-induced fibrosis."4.79[The treatment of cutaneous radiation-induced fibrosis with pentoxifylline and vitamin E. An empirical report]. ( Gottlöber, P; Korting, HC; Krähn, G; Peter, RU; Stock, W, 1996)
"This study is a retrospective review of treatment outcomes of osteoradionecrosis (ORN) of the mandible with specific reference to the evolving role of medical management with pentoxifylline, tocopherol, and doxycycline."3.80Changing trends and the role of medical management on the outcome of patients treated for osteoradionecrosis of the mandible: experience from a regional head and neck unit. ( D'Souza, J; Lowe, D; Rogers, SN, 2014)
"The influence of pentoxifylline on radiotoxicity was assessed by colony assay in TP53 wild-type Bell and mutant MeWo melanoma, and in TP53 wild-type 4197 and mutant 4451 squamous cell carcinoma (SCC) cell lines."3.70The role of G2-block abrogation, DNA double-strand break repair and apoptosis in the radiosensitization of melanoma and squamous cell carcinoma cell lines by pentoxifylline. ( Binder, A; Böhm, L; Theron, T; Verheye-Dua, F, 2000)
"The pentoxifylline was continued between chemotherapy cycles."2.67Cisplatin, cytosine arabinoside, and pentoxifylline in the treatment of squamous cell carcinoma of the head and neck. ( Cripps, MC; Fingert, H; Gerin-Lajoie, J; Laframboise, G; Lamothe, A; Stewart, DJ, 1993)
"Osteoradionecrosis is a complication of head and neck radiotherapy, with a difficult resolution and no well-established treatment."1.43Tissue repair in osteoradionecrosis using pentoxifylline and tocopherol--report of three cases. ( Bohn, JC; Sassi, LM; Schussel, JL; Stramandinoli-Zanicotti, RT, 2016)
"Three squamous cell carcinoma cell lines, FaDu, RPMI 2650 and SCC-61, with differences in genomic imbalance and intrinsic radiosensitivity, were irradiated with 140 cGy/min (HDRI) and 0."1.33The biological effect of pentoxifylline on the survival of human head and neck cancer cells treated with continuous low and high dose-rate irradiation. ( Danielsson, A; Delle, U; Helou, K; Karlsson, E; Mercke, C, 2005)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (16.67)18.2507
2000's8 (66.67)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
D'Souza, J1
Lowe, D1
Rogers, SN1
Bohn, JC1
Schussel, JL1
Stramandinoli-Zanicotti, RT1
Sassi, LM1
Wheeler, DL1
Ness, KJ1
Oberley, TD1
Verma, AK1
Aygenc, E1
Celikkanat, S1
Kaymakci, M1
Aksaray, F1
Ozdem, C1
Danielsson, A1
Karlsson, E1
Delle, U1
Helou, K1
Mercke, C1
Hanly, AM1
Hayanga, A1
Winter, DC1
Bouchier-Hayes, DJ1
Amano, M1
Monzen, H1
Suzuki, M1
Terai, K1
Andoh, S1
Tsumuraya, A1
Hasegawa, T1
Stewart, DJ1
Cripps, MC1
Fingert, H1
Lamothe, A1
Laframboise, G1
Gerin-Lajoie, J1
Gottlöber, P1
Krähn, G1
Korting, HC1
Stock, W1
Peter, RU1
Theron, T1
Binder, A1
Verheye-Dua, F1
Böhm, L1
Mannel, RS1
Blessing, JA1
Boike, G1
Binder, AB1
Serafin, AM1
Bohm, LJ1

Reviews

2 reviews available for pentoxifylline and Carcinoma, Squamous Cell

ArticleYear
Thrombomodulin: tumour biology and prognostic implications.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2005, Volume: 31, Issue:3

    Topics: Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Down-Regulation; Gene Expression Regulatio

2005
[The treatment of cutaneous radiation-induced fibrosis with pentoxifylline and vitamin E. An empirical report].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1996, Volume: 172, Issue:1

    Topics: Breast Neoplasms; Carcinoma, Squamous Cell; Combined Modality Therapy; Drug Therapy, Combination; Fe

1996

Trials

3 trials available for pentoxifylline and Carcinoma, Squamous Cell

ArticleYear
Prophylactic effect of pentoxifylline on radiotherapy complications: a clinical study.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2004, Volume: 130, Issue:3

    Topics: Aged; Carcinoma, Squamous Cell; Chemoprevention; Head and Neck Neoplasms; Humans; Male; Middle Aged;

2004
Cisplatin, cytosine arabinoside, and pentoxifylline in the treatment of squamous cell carcinoma of the head and neck.
    American journal of clinical oncology, 1993, Volume: 16, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Cy

1993
Cisplatin and pentoxifylline in advanced or recurrent squamous cell carcinoma of the cervix: a phase II trial of the Gynecologic Oncology Group.
    Gynecologic oncology, 2000, Volume: 79, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols

2000

Other Studies

7 other studies available for pentoxifylline and Carcinoma, Squamous Cell

ArticleYear
Changing trends and the role of medical management on the outcome of patients treated for osteoradionecrosis of the mandible: experience from a regional head and neck unit.
    The British journal of oral & maxillofacial surgery, 2014, Volume: 52, Issue:4

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Antioxidants; Carcinoma, Squamous Cell; Debridement;

2014
Tissue repair in osteoradionecrosis using pentoxifylline and tocopherol--report of three cases.
    Oral and maxillofacial surgery, 2016, Volume: 20, Issue:1

    Topics: Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Thera

2016
Protein kinase Cepsilon is linked to 12-O-tetradecanoylphorbol-13-acetate-induced tumor necrosis factor-alpha ectodomain shedding and the development of metastatic squamous cell carcinoma in protein kinase Cepsilon transgenic mice.
    Cancer research, 2003, Oct-01, Volume: 63, Issue:19

    Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Female; Keratinocytes; Male; Mice; Mice, Inbred C57B

2003
The biological effect of pentoxifylline on the survival of human head and neck cancer cells treated with continuous low and high dose-rate irradiation.
    Journal of cancer research and clinical oncology, 2005, Volume: 131, Issue:7

    Topics: Carcinoma, Squamous Cell; Cell Proliferation; Cell Survival; DNA Repair; Dose-Response Relationship,

2005
Increase in tumor oxygenation and potentiation of radiation effects using pentoxifylline, vinpocetine and ticlopidine hydrochloride.
    Journal of radiation research, 2005, Volume: 46, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Mice; Mice, Inbred C3H; Oxi

2005
The role of G2-block abrogation, DNA double-strand break repair and apoptosis in the radiosensitization of melanoma and squamous cell carcinoma cell lines by pentoxifylline.
    International journal of radiation biology, 2000, Volume: 76, Issue:9

    Topics: Apoptosis; Carcinoma, Squamous Cell; DNA; DNA Damage; DNA Repair; Dose-Response Relationship, Radiat

2000
Abrogation of G(2)/M-phase block enhances the cytotoxicity of daunorubicin, melphalan and cisplatin in TP53 mutant human tumor cells.
    Radiation research, 2000, Volume: 154, Issue:6

    Topics: Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cel

2000