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pentoxifylline and Candidiasis

pentoxifylline has been researched along with Candidiasis in 9 studies

Candidiasis: Infection with a fungus of the genus CANDIDA. It is usually a superficial infection of the moist areas of the body and is generally caused by CANDIDA ALBICANS. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"Since fungal septic shock with acute disseminated candidiasis evolves prior to significant increases in circulating TNF, PTX also appears ineffective in its treatment."5.29Effects of pentoxifylline on tumor necrosis factor production and survival during lethal E. coli sepsis vs. disseminated candidiasis with fungal septic shock. ( Lechner, AJ; Matuschak, GM; Potthoff, LH; Rouben, LR; Tredway, TL, 1993)
" The toxic and antifungal effects of AmB with and without the vascular decongestants pentoxifylline (PTX) and a methylxanthine analog, HWA-138, were compared in the murine model of candidiasis."3.68Enhancement of the treatment of experimental candidiasis with vascular decongestants. ( Lopez-Berestein, G; Luke, DR; McQueen, TJ; Wasan, KM, 1990)
"Pentoxifylline has immunomodulatory properties and has been shown to decrease organ damage and improve survival in animals with gram-negative sepsis or endotoxemia."1.30Pharmacokinetics of pentoxifylline and its metabolites in healthy mice and in mice infected with Candida albicans. ( Baltch, AL; Davis, PJ; Gordon, MA; Louie, A; Miller, K; Smith, RP, 1998)
"Since fungal septic shock with acute disseminated candidiasis evolves prior to significant increases in circulating TNF, PTX also appears ineffective in its treatment."1.29Effects of pentoxifylline on tumor necrosis factor production and survival during lethal E. coli sepsis vs. disseminated candidiasis with fungal septic shock. ( Lechner, AJ; Matuschak, GM; Potthoff, LH; Rouben, LR; Tredway, TL, 1993)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (88.89)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Farkas, G1
Márton, J1
Mándi, Y1
Leindler, L1
Netea, MG1
Blok, WL1
Kullberg, BJ1
Bemelmans, M1
Vogels, MT1
Buurman, WA1
van der Meer, JW1
Lechner, AJ1
Rouben, LR1
Potthoff, LH1
Tredway, TL1
Matuschak, GM1
Louie, A2
Baltch, AL2
Franke, MA1
Ritz, WJ1
Smith, RP2
Singh, JK1
Gordon, MA2
Miller, K1
Davis, PJ1
Wasan, KM3
Vadiei, K2
Luke, DR3
Keyhani, A1
White, RA1
McQueen, TJ2
Mehta, R1
Lopez-Berestein, G3
Verani, RR1
Brunner, LJ1
Berens, KL1
Montgomery, B1
Bianco, JA1
Jacobsen, A1
Singer, JW1

Other Studies

9 other studies available for pentoxifylline and Candidiasis

ArticleYear
Surgical management and complex treatment of infected pancreatic necrosis: 18-year experience at a single center.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2006, Volume: 10, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents; Arginine; Candidiasis; Cause of Death; Cholecystectomy; Colec

2006
Pharmacologic inhibitors of tumor necrosis factor production exert differential effects in lethal endotoxemia and in infection with live microorganisms in mice.
    The Journal of infectious diseases, 1995, Volume: 171, Issue:2

    Topics: Animals; Candidiasis; Chlorpromazine; Female; Interleukin-1; Kidney; Klebsiella Infections; Klebsiel

1995
Effects of pentoxifylline on tumor necrosis factor production and survival during lethal E. coli sepsis vs. disseminated candidiasis with fungal septic shock.
    Circulatory shock, 1993, Volume: 39, Issue:4

    Topics: Animals; Bacteremia; Candidiasis; Escherichia coli Infections; Fungemia; Gene Expression; Male; Pent

1993
Effect of pentoxifylline on the course of systemic Candida albicans infection in mice.
    The Journal of antimicrobial chemotherapy, 1996, Volume: 37, Issue:5

    Topics: Animals; Antifungal Agents; Candidiasis; Endotoxins; Humans; Interleukin-6; Kidney; Leukocyte Count;

1996
Pharmacokinetics of pentoxifylline and its metabolites in healthy mice and in mice infected with Candida albicans.
    Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:9

    Topics: Adjuvants, Immunologic; Animals; Candidiasis; Female; Mice; Pentoxifylline

1998
Antifungal activity of HWA-138 and amphotericin B in experimental systemic candidiasis.
    Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:10

    Topics: Amphotericin B; Animals; Antifungal Agents; Candidiasis; Drug Synergism; Mice; Mice, Inbred ICR; Pen

1991
Attenuation of amphotericin-B nephrotoxicity in the candidiasis rat model.
    Nephron, 1991, Volume: 59, Issue:1

    Topics: Amphotericin B; Animals; Candidiasis; Dose-Response Relationship, Drug; Kidney; Male; Pentoxifylline

1991
Localization of transfused neutrophils to site of infection during treatment with recombinant human granulocyte-macrophage colony-stimulating factor and pentoxifylline.
    Blood, 1991, Jul-15, Volume: 78, Issue:2

    Topics: Abscess; Adult; Blood Transfusion; Bone Marrow Transplantation; Candidiasis; Granulocyte-Macrophage

1991
Enhancement of the treatment of experimental candidiasis with vascular decongestants.
    The Journal of infectious diseases, 1990, Volume: 162, Issue:1

    Topics: Amphotericin B; Animals; Candidiasis; Drug Therapy, Combination; Glomerular Filtration Rate; Kidney;

1990