pentoxifylline has been researched along with Cancer of Cervix in 8 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Of 30 patients with radiation-induced proctitis/enteritis grade I-II according to the RTOG/EORTC toxicity criteria, 21 were treated with pentoxifylline and tocopherol." | 7.73 | Effect of pentoxifylline and tocopherol on radiation proctitis/enteritis. ( Christiansen, H; Hermann, RM; Hess, CF; Hilgers, R; Hille, A; Pradier, O; Schmidberger, H; Siekmeyer, B; Weiss, E, 2005) |
| "Of 30 patients with radiation-induced proctitis/enteritis grade I-II according to the RTOG/EORTC toxicity criteria, 21 were treated with pentoxifylline and tocopherol." | 3.73 | Effect of pentoxifylline and tocopherol on radiation proctitis/enteritis. ( Christiansen, H; Hermann, RM; Hess, CF; Hilgers, R; Hille, A; Pradier, O; Schmidberger, H; Siekmeyer, B; Weiss, E, 2005) |
| "Worldwide, cervical cancer is the second most common causes of cancer in women and represents an important mortality rate." | 1.37 | Pentoxifylline sensitizes human cervical tumor cells to cisplatin-induced apoptosis by suppressing NF-kappa B and decreased cell senescence. ( Aguilar-Lemarroy, Adel C; Bravo-Cuellar, A; Castellanos-Esparza, YC; de Celis-Carrillo, R; del Toro-Arreola, S; Dominguez-Rodriguez, JR; Hernandez-Flores, G; Jave-Suarez, LF; Lerma-Diaz, JM; Ortiz-Lazareno, PC, 2011) |
| "HeLa (HPV 18+), SiHa (HPV 16+) cervix cancer cells and non-tumorigenic immortalized HaCaT cells (control) were treated with PTX, ADR or PTX + ADR." | 1.36 | Sensitization of cervix cancer cells to Adriamycin by Pentoxifylline induces an increase in apoptosis and decrease senescence. ( Aguilar-Lemarroy, A; Bravo-Cuellar, A; de Alba-Garcia, JE; de Celis-Carrillo, R; del Toro-Arreola, S; Dominguez-Rodriguez, JR; Hernandez-Flores, G; Jave-Suarez, LF; Lerma-Diaz, JM; Ortiz-Lazareno, PC; Sahagun-Flores, JE, 2010) |
| "Caffeine is a commonly consumed methylxanthine that provides a model for evaluating the impact of this category of drugs on radiation injury." | 1.29 | Caffeine consumption is associated with decreased severe late toxicity after radiation to the pelvis. ( Greer, BE; Griffin, TW; Koh, WJ; Kurtz, H; Stelzer, KJ, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Palafox-Mariscal, LA | 1 |
| Ortiz-Lazareno, PC | 3 |
| Jave-Suárez, LF | 3 |
| Aguilar-Lemarroy, A | 2 |
| Villaseñor-García, MM | 1 |
| Cruz-Lozano, JR | 1 |
| González-Martínez, KL | 1 |
| Méndez-Clemente, AS | 1 |
| Bravo-Cuellar, A | 3 |
| Hernández-Flores, G | 3 |
| Lerma-Diaz, JM | 2 |
| Dominguez-Rodriguez, JR | 2 |
| del Toro-Arreola, S | 2 |
| de Celis-Carrillo, R | 2 |
| Sahagun-Flores, JE | 1 |
| de Alba-Garcia, JE | 1 |
| Aguilar-Lemarroy, Adel C | 1 |
| Castellanos-Esparza, YC | 1 |
| Hille, A | 1 |
| Christiansen, H | 1 |
| Pradier, O | 1 |
| Hermann, RM | 1 |
| Siekmeyer, B | 1 |
| Weiss, E | 1 |
| Hilgers, R | 1 |
| Hess, CF | 1 |
| Schmidberger, H | 1 |
| Stelzer, KJ | 1 |
| Koh, WJ | 1 |
| Kurtz, H | 1 |
| Greer, BE | 1 |
| Griffin, TW | 1 |
| Li, YX | 1 |
| Weber-Johnson, K | 1 |
| Sun, LQ | 1 |
| Paschoud, N | 1 |
| Mirimanoff, RO | 1 |
| Coucke, PA | 1 |
| Mannel, RS | 1 |
| Blessing, JA | 1 |
| Boike, G | 1 |
| Boike, GM | 1 |
| Petru, E | 1 |
| Sevin, BU | 1 |
| Averette, HE | 1 |
| Chou, TC | 1 |
| Penalver, M | 1 |
| Donato, D | 1 |
| Schiano, M | 1 |
| Hilsenbeck, SG | 1 |
| Perras, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Enhancing Effect on Tumour Apoptosis With the Combined Use of Pentoxifylline Plus Chemotherapeutical Agents in Pediatrics and AYA Patients With Hodgkin´s Lymphoma[NCT05490953] | Phase 4 | 30 participants (Anticipated) | Interventional | 2022-07-11 | Recruiting | ||
| SAFETY AND EFFICACY OF PENTOXIFYLLINE VERSUS PLACEBO ADMINISTERED AS APOPTOSIS INDUCTOR DURING REMISSION INDUCTION PHASE OF PEDIATRIC PATIENTS WITH ACUTE LYMPHOBLASTIC LEUKEMIA[NCT02451774] | Phase 2/Phase 3 | 44 participants (Anticipated) | Interventional | 2015-01-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for pentoxifylline and Cancer of Cervix
| Article | Year |
|---|---|
Cisplatin and pentoxifylline in advanced or recurrent squamous cell carcinoma of the cervix: a phase II trial of the Gynecologic Oncology Group.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols | 2000 |
7 other studies available for pentoxifylline and Cancer of Cervix
| Article | Year |
|---|---|
Pentoxifylline Inhibits TNF-α/TGF-β1-Induced Epithelial-Mesenchymal Transition via Suppressing the NF-κB Pathway and
Topics: Cadherins; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Female; Humans; NF-kappa B; Pentoxif | 2023 |
Sensitization of cervix cancer cells to Adriamycin by Pentoxifylline induces an increase in apoptosis and decrease senescence.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Caspases; Cell Line, T | 2010 |
Pentoxifylline sensitizes human cervical tumor cells to cisplatin-induced apoptosis by suppressing NF-kappa B and decreased cell senescence.
Topics: Adult; Annexin A5; Antineoplastic Agents; Apoptosis; bcl-X Protein; Caspases; Cell Line, Tumor; Cell | 2011 |
Pentoxifylline sensitizes human cervical tumor cells to cisplatin-induced apoptosis by suppressing NF-kappa B and decreased cell senescence.
Topics: Adult; Annexin A5; Antineoplastic Agents; Apoptosis; bcl-X Protein; Caspases; Cell Line, Tumor; Cell | 2011 |
Pentoxifylline sensitizes human cervical tumor cells to cisplatin-induced apoptosis by suppressing NF-kappa B and decreased cell senescence.
Topics: Adult; Annexin A5; Antineoplastic Agents; Apoptosis; bcl-X Protein; Caspases; Cell Line, Tumor; Cell | 2011 |
Pentoxifylline sensitizes human cervical tumor cells to cisplatin-induced apoptosis by suppressing NF-kappa B and decreased cell senescence.
Topics: Adult; Annexin A5; Antineoplastic Agents; Apoptosis; bcl-X Protein; Caspases; Cell Line, Tumor; Cell | 2011 |
Effect of pentoxifylline and tocopherol on radiation proctitis/enteritis.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antioxidants; Chi-Square Distribution; Data In | 2005 |
Caffeine consumption is associated with decreased severe late toxicity after radiation to the pelvis.
Topics: Caffeine; Endometrial Neoplasms; Female; Humans; Pelvis; Pentoxifylline; Radiation-Protective Agents | 1994 |
Effect of pentoxifylline on radiation-induced G2-phase delay and radiosensitivity of human colon and cervical cancer cells.
Topics: Cell Cycle; Colonic Neoplasms; Female; G2 Phase; Gamma Rays; Humans; Pentoxifylline; Radiation-Sensi | 1998 |
Chemical enhancement of cisplatin cytotoxicity in a human ovarian and cervical cancer cell line.
Topics: Adenosine Triphosphate; Benzamides; Caffeine; Cells, Cultured; Cisplatin; Dose-Response Relationship | 1990 |