pentoxifylline has been researched along with Bronchopulmonary Dysplasia in 6 studies
Bronchopulmonary Dysplasia: A chronic lung disease developed after OXYGEN INHALATION THERAPY or mechanical ventilation (VENTILATION, MECHANICAL) usually occurring in certain premature infants (INFANT, PREMATURE) or newborn infants with respiratory distress syndrome (RESPIRATORY DISTRESS SYNDROME, NEWBORN). Histologically, it is characterized by the unusual abnormalities of the bronchioles, such as METAPLASIA, decrease in alveolar number, and formation of CYSTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the effectiveness of nebulized pentoxifylline (PTXF) compared to intravenous dexamethasone (DX) or placebo (nebulized distilled water) for the prevention of bronchopulmonary dysplasia (BPD)." | 9.12 | Nebulized pentoxifylline for prevention of bronchopulmonary dysplasia in very low birth weight infants: a pilot clinical study. ( Lauterbach, R; Lisowska-Miszczyk, I; Pawlik, D; Rytlewski, K; Szymura-Oleksiak, J; Warchoł, J, 2006) |
| "To evaluate the efficacy and safety of nebulized pentoxifylline for reducing the duration of oxygen supplementation in extremely preterm neonates at high risk of bronchopulmonary dysplasia (BPD)." | 5.20 | Nebulized pentoxifylline for reducing the duration of oxygen supplementation in extremely preterm neonates. ( Deshmukh, M; Doherty, DA; Nathan, EA; Patole, SK; Schulzke, SM, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Papagianis, PC | 1 |
| Pillow, JJ | 1 |
| Moss, TJ | 1 |
| Schulzke, SM | 2 |
| Kaempfen, S | 1 |
| Patole, SK | 2 |
| Deshmukh, M | 1 |
| Nathan, EA | 1 |
| Doherty, DA | 1 |
| Demir, K | 1 |
| Kumral, A | 1 |
| Duman, N | 1 |
| Sarioglu, S | 1 |
| Yilmaz, O | 1 |
| Yesilirmak, DC | 1 |
| Kargi, A | 1 |
| Ozkan, H | 1 |
| Lauterbach, R | 2 |
| Szymura-Oleksiak, J | 2 |
| Pawlik, D | 1 |
| Warchoł, J | 1 |
| Lisowska-Miszczyk, I | 1 |
| Rytlewski, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Gastroesophageal Reflux Poses a Potential Risk for Late Complications of BPD: A Prospective Study[NCT03014453] | 187 participants (Actual) | Observational | 2017-01-09 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
In all patients, complications were evaluated via questionnaires at 3, 6, 9 and 12 months corrected for premature age, including respiratory symptoms (including home respiratory support, respiratory medication administration, cough without cold at least once per week, re-hospitalization due to respiratory diseases), vomiting when feeding, hypoxic ischemic injury, retinopathy of prematurity, rehospitalization and sudden death. (NCT03014453)
Timeframe: 18 months
| Intervention | Participants (Count of Participants) | |||||
|---|---|---|---|---|---|---|
| respiratory symptoms | Vomiting when feeding | retinopathy of prematurity | hypoxic ischemic injury | sudden infant death syndrome | rehospitalization | |
| Extremely Premature Infants With Bronchopulmonary Dysplasia | 57 | 45 | 30 | 4 | 1 | 31 |
2 reviews available for pentoxifylline and Bronchopulmonary Dysplasia
| Article | Year |
|---|---|
Bronchopulmonary dysplasia: Pathophysiology and potential anti-inflammatory therapies.
Topics: Anti-Inflammatory Agents; Bronchopulmonary Dysplasia; Chorioamnionitis; Dexamethasone; Female; Fetal | 2019 |
Pentoxifylline for the prevention of bronchopulmonary dysplasia in preterm infants.
Topics: Bronchopulmonary Dysplasia; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Infant, Pre | 2014 |
3 trials available for pentoxifylline and Bronchopulmonary Dysplasia
| Article | Year |
|---|---|
Nebulized pentoxifylline for reducing the duration of oxygen supplementation in extremely preterm neonates.
Topics: Bronchopulmonary Dysplasia; Continuous Positive Airway Pressure; Double-Blind Method; Female; Humans | 2015 |
Nebulized pentoxifylline for prevention of bronchopulmonary dysplasia in very low birth weight infants: a pilot clinical study.
Topics: Bronchopulmonary Dysplasia; Dexamethasone; Drug Therapy, Combination; Glucocorticoids; Humans; Infan | 2006 |
Nebulized pentoxifylline in successful treatment of five premature neonates with bronchopulmonary dysplasia.
Topics: Administration, Inhalation; Bronchopulmonary Dysplasia; Drug Administration Schedule; Enzyme Inhibit | 1999 |
1 other study available for pentoxifylline and Bronchopulmonary Dysplasia
| Article | Year |
|---|---|
Clarithromycin, montelukast, and pentoxifylline combination treatment ameliorates experimental neonatal hyperoxic lung injury.
Topics: Acetates; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Bronchopulmonary Dyspl | 2008 |