pentoxifylline has been researched along with Bronchial Hyperreactivity in 5 studies
Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tranilast has been used in allergic diseases because of its inhibitory effect on mast cells; it also has an anti-fibrotic effect in several diseases." | 5.35 | Effects of tranilast and pentoxifylline in a mouse model of chronic asthma using house dust mite antigen. ( Ahn, JH; Kim, CH; Kim, JS; Kim, JW; Kim, SC; Kim, SJ; Kim, YH; Kim, YK; Kwon, SS; Lee, JM; Lee, SH; Lee, SY; Yoon, HK, 2009) |
| "Pentoxifylline (PTX) has been shown to reduce sepsis-induced neutrophil sequestration in the lung and inhibit endotoxin-mediated release of tumor necrosis factor-alpha (TNF-alpha)." | 2.68 | Pentoxifylline does not alter the response to inhaled grain dust. ( Jagielo, PJ; Knapp, HR; Quinn, TJ; Schwartz, DA; Watt, JL, 1997) |
| "Tranilast has been used in allergic diseases because of its inhibitory effect on mast cells; it also has an anti-fibrotic effect in several diseases." | 1.35 | Effects of tranilast and pentoxifylline in a mouse model of chronic asthma using house dust mite antigen. ( Ahn, JH; Kim, CH; Kim, JS; Kim, JW; Kim, SC; Kim, SJ; Kim, YH; Kim, YK; Kwon, SS; Lee, JM; Lee, SH; Lee, SY; Yoon, HK, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, SJ | 1 |
| Kim, JW | 1 |
| Kim, YH | 1 |
| Lee, SH | 1 |
| Yoon, HK | 1 |
| Kim, CH | 1 |
| Ahn, JH | 1 |
| Lee, JM | 1 |
| Kim, JS | 1 |
| Kim, SC | 1 |
| Lee, SY | 1 |
| Kwon, SS | 1 |
| Kim, YK | 1 |
| Rolla, G | 1 |
| Bucca, C | 1 |
| Brussino, L | 1 |
| Dutto, L | 1 |
| Colagrande, P | 1 |
| Polizzi, S | 1 |
| Uno, T | 1 |
| Tanaka, H | 1 |
| Nakai, N | 1 |
| Nagai, H | 1 |
| Jagielo, PJ | 1 |
| Watt, JL | 1 |
| Quinn, TJ | 1 |
| Knapp, HR | 1 |
| Schwartz, DA | 1 |
| Fleming, CM | 1 |
| He, H | 1 |
| Ciota, A | 1 |
| Perkins, D | 1 |
| Finn, PW | 1 |
2 trials available for pentoxifylline and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Pentoxifylline attenuates LPS-induced bronchial hyperresponsiveness but not the increase in exhaled nitric oxide.
Topics: Adult; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cross-Over Studies; Double-Blind Meth | 1997 |
Pentoxifylline does not alter the response to inhaled grain dust.
Topics: Administration, Inhalation; Adult; Airway Obstruction; Bronchial Hyperreactivity; Bronchoalveolar La | 1997 |
3 other studies available for pentoxifylline and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Effects of tranilast and pentoxifylline in a mouse model of chronic asthma using house dust mite antigen.
Topics: Animals; Anti-Allergic Agents; Antigens, Dermatophagoides; Asthma; Bronchial Hyperreactivity; Bronch | 2009 |
Participation of leukotriene D4 and tumor necrosis factor on lipopolysaccharide-induced airway hyperresponsiveness in guinea pigs.
Topics: Acetylcholine; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Bronchoconstriction | 1997 |
Administration of pentoxifylline during allergen sensitization dissociates pulmonary allergic inflammation from airway hyperresponsiveness.
Topics: Aerosols; Allergens; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cytokines; Dr | 2001 |