Page last updated: 2024-11-02

pentoxifylline and Brain Injuries

pentoxifylline has been researched along with Brain Injuries in 3 studies

Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.

Research Excerpts

ExcerptRelevanceReference
"Early brain injury (EBI) after subarachnoid hemorrhage (SAH) generally causes significant and lasting damage."5.46Pentoxifylline Alleviates Early Brain Injury After Experimental Subarachnoid Hemorrhage in Rats: Possibly via Inhibiting TLR 4/NF-κB Signaling Pathway. ( Hang, CH; Wu, LY; Xia, DY; Zhang, HS; Zhang, XS; Zhou, ML, 2017)
"Pentoxifylline (PTX) is a methylxanthine derivative clinically proven to improve perfusion in the peripheral microcirculation and has been shown to have neuroprotective effects in brain trauma and global cerebral ischemia in experimental animal models."5.43Pentoxifylline Alleviates Early Brain Injury in a Rat Model of Subarachnoid Hemorrhage. ( Aslan, M; Demır, N; Dilmac, S; Dogan, O; Goksu, E; Kirac, E; Konuk, E; Tanrıover, G; Ulker, P, 2016)
"Early brain injury (EBI) after subarachnoid hemorrhage (SAH) generally causes significant and lasting damage."1.46Pentoxifylline Alleviates Early Brain Injury After Experimental Subarachnoid Hemorrhage in Rats: Possibly via Inhibiting TLR 4/NF-κB Signaling Pathway. ( Hang, CH; Wu, LY; Xia, DY; Zhang, HS; Zhang, XS; Zhou, ML, 2017)
"Pentoxifylline (PTX) is a methylxanthine derivative clinically proven to improve perfusion in the peripheral microcirculation and has been shown to have neuroprotective effects in brain trauma and global cerebral ischemia in experimental animal models."1.43Pentoxifylline Alleviates Early Brain Injury in a Rat Model of Subarachnoid Hemorrhage. ( Aslan, M; Demır, N; Dilmac, S; Dogan, O; Goksu, E; Kirac, E; Konuk, E; Tanrıover, G; Ulker, P, 2016)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goksu, E1
Dogan, O1
Ulker, P1
Tanrıover, G1
Konuk, E1
Dilmac, S1
Kirac, E1
Demır, N1
Aslan, M1
Xia, DY1
Zhang, HS1
Wu, LY1
Zhang, XS1
Zhou, ML1
Hang, CH1
Jean Harry, G1
Bruccoleri, A1
Lefebvre d'Hellencourt, C1

Other Studies

3 other studies available for pentoxifylline and Brain Injuries

ArticleYear
Pentoxifylline Alleviates Early Brain Injury in a Rat Model of Subarachnoid Hemorrhage.
    Acta neurochirurgica, 2016, Volume: 158, Issue:9

    Topics: Animals; Blood-Brain Barrier; Brain Edema; Brain Injuries; Disease Models, Animal; Inflammation; Mal

2016
Pentoxifylline Alleviates Early Brain Injury After Experimental Subarachnoid Hemorrhage in Rats: Possibly via Inhibiting TLR 4/NF-κB Signaling Pathway.
    Neurochemical research, 2017, Volume: 42, Issue:4

    Topics: Animals; Brain Injuries; Male; NF-kappa B; Pentoxifylline; Phosphodiesterase Inhibitors; Random Allo

2017
Differential modulation of hippocampal chemical-induced injury response by ebselen, pentoxifylline, and TNFalpha-, IL-1alpha-, and IL-6-neutralizing antibodies.
    Journal of neuroscience research, 2003, Aug-15, Volume: 73, Issue:4

    Topics: Animals; Antibodies; Azoles; Brain Injuries; Cerebellum; Cytokines; Disease Models, Animal; Drug Com

2003