Page last updated: 2024-11-02

pentoxifylline and Bisphosphonate Osteonecrosis

pentoxifylline has been researched along with Bisphosphonate Osteonecrosis in 7 studies

Research Excerpts

ExcerptRelevanceReference
"Evaluate the effect of pentoxifylline and α-tocopherol administration in the prevention or treatment of medication-related jaw osteonecrosis (MRONJ)."8.12Effect of pentoxifylline and α-tocopherol on medication-related osteonecrosis of the jaw in rats: Before and after dental extraction. ( Andreis, JD; Claudino, M; Delfrate, G; Fernandes, D; Franco, GCN; Lipinski, LC; Mecca, LEA; Mroczek, T, 2022)
"Zoledronic acid is a third-generation nitrogen-containing BP."5.40Pentoxifylline and tocopherol in the treatment of yearly zoledronic acid-related osteonecrosis of the jaw in a corticosteroid-induced osteoporosis. ( Magremanne, M; Reychler, H, 2014)
" Interest in pentoxifylline and tocopherol is growing because these agents have been shown to be effective in treating osteoradionecrosis of the jaw."5.01Systematic review of the use of pentoxifylline and tocopherol for the treatment of medication-related osteonecrosis of the jaw. ( Abdelsamie, S; Campbell, CB; Fielding, AF; Heifetz-Li, JJ; Mulligan, JP; Roth, S, 2019)
"Evaluate the effect of pentoxifylline and α-tocopherol administration in the prevention or treatment of medication-related jaw osteonecrosis (MRONJ)."4.12Effect of pentoxifylline and α-tocopherol on medication-related osteonecrosis of the jaw in rats: Before and after dental extraction. ( Andreis, JD; Claudino, M; Delfrate, G; Fernandes, D; Franco, GCN; Lipinski, LC; Mecca, LEA; Mroczek, T, 2022)
"Breast cancer was the most predominant neoplasm (70."1.91Pentoxifylline and tocopherol as prophylaxis for osteonecrosis of the jaw due to bone-modifying agents in patients with cancer submitted to tooth extraction: a case series. ( da Motta Silveira, FM; de Andrade Veras, SR; de Lima E Silva, DF; de Mello, MJG; Magalhães, JMI; Regueira, LS, 2023)
"Zoledronic acid is a third-generation nitrogen-containing BP."1.40Pentoxifylline and tocopherol in the treatment of yearly zoledronic acid-related osteonecrosis of the jaw in a corticosteroid-induced osteoporosis. ( Magremanne, M; Reychler, H, 2014)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (57.14)24.3611
2020's3 (42.86)2.80

Authors

AuthorsStudies
Delfrate, G1
Mroczek, T1
Mecca, LEA1
Andreis, JD1
Fernandes, D1
Lipinski, LC1
Claudino, M1
Franco, GCN1
Magalhães, JMI1
da Motta Silveira, FM1
Regueira, LS1
de Lima E Silva, DF1
de Andrade Veras, SR1
de Mello, MJG1
Heifetz-Li, JJ1
Abdelsamie, S1
Campbell, CB1
Roth, S1
Fielding, AF1
Mulligan, JP1
Cavalcante, RC1
Tomasetti, G1
Magremanne, M1
Reychler, H1
Janovszky, Á1
Vereb, T1
Szabó, A1
Piffkó, J1
Owosho, AA1
Estilo, CL1
Huryn, JM1
Yom, SK1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pentoxifylline and Tocopherol (PENTO) in the Treatment of Medication-related Osteonecrosis of the Jaw (MRONJ): A Prospective, Randomized Controlled Trial to Evaluate a Novel Non-operative Treatment[NCT03040778]Phase 3100 participants (Anticipated)Interventional2018-04-01Enrolling by invitation
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for pentoxifylline and Bisphosphonate Osteonecrosis

ArticleYear
Systematic review of the use of pentoxifylline and tocopherol for the treatment of medication-related osteonecrosis of the jaw.
    Oral surgery, oral medicine, oral pathology and oral radiology, 2019, Volume: 128, Issue:5

    Topics: Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Humans; Osteor

2019
Pentoxifylline and tocopherol protocol to treat medication-related osteonecrosis of the jaw: A systematic literature review.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2020, Volume: 48, Issue:11

    Topics: Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Diphosphonates

2020
[Current approaches for early detection and treatment of medication-related osteonecrosis of jaw].
    Orvosi hetilap, 2014, Dec-07, Volume: 155, Issue:49

    Topics: alpha-Tocopherol; Analgesics; Anti-Bacterial Agents; Biomarkers; Bisphosphonate-Associated Osteonecr

2014

Other Studies

4 other studies available for pentoxifylline and Bisphosphonate Osteonecrosis

ArticleYear
Effect of pentoxifylline and α-tocopherol on medication-related osteonecrosis of the jaw in rats: Before and after dental extraction.
    Archives of oral biology, 2022, Volume: 137

    Topics: alpha-Tocopherol; Animals; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conserva

2022
Pentoxifylline and tocopherol as prophylaxis for osteonecrosis of the jaw due to bone-modifying agents in patients with cancer submitted to tooth extraction: a case series.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2023, Jul-12, Volume: 31, Issue:8

    Topics: Adolescent; Adult; Aged; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservati

2023
Pentoxifylline and tocopherol in the treatment of yearly zoledronic acid-related osteonecrosis of the jaw in a corticosteroid-induced osteoporosis.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2014, Volume: 72, Issue:2

    Topics: Adrenal Cortex Hormones; Alendronate; Antioxidants; Bisphosphonate-Associated Osteonecrosis of the J

2014
Pentoxifylline and tocopherol in the management of cancer patients with medication-related osteonecrosis of the jaw: an observational retrospective study of initial case series.
    Oral surgery, oral medicine, oral pathology and oral radiology, 2016, Volume: 122, Issue:4

    Topics: Aged; Antioxidants; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Ag

2016