pentoxifylline has been researched along with Bacteremia in 11 studies
Bacteremia: The presence of viable bacteria circulating in the blood. Fever, chills, tachycardia, and tachypnea are common acute manifestations of bacteremia. The majority of cases are seen in already hospitalized patients, most of whom have underlying diseases or procedures which render their bloodstreams susceptible to invasion.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to investigate whether the methylxanthine-derivative pentoxifylline (PTX) affects bacterial clearance of the organism in states of hemorrhage and endotoxemia." | 7.70 | Pentoxifylline improves bacterial clearance during hemorrhage and endotoxemia. ( Heller, A; Heller, S; Koch, T; Urbaschek, R; Weber, K, 1999) |
| "In vivo videomicroscopy was used to quantitate alterations of the small-intestine microcirculation during Escherichia coli bacteremia in rats pretreated with either intravenous pentoxifylline or saline solution." | 7.68 | Pentoxifylline preserves small-intestine microvascular blood flow during bacteremia. ( Garrison, RN; Steeb, GD; Wilson, MA, 1992) |
| "Since fungal septic shock with acute disseminated candidiasis evolves prior to significant increases in circulating TNF, PTX also appears ineffective in its treatment." | 5.29 | Effects of pentoxifylline on tumor necrosis factor production and survival during lethal E. coli sepsis vs. disseminated candidiasis with fungal septic shock. ( Lechner, AJ; Matuschak, GM; Potthoff, LH; Rouben, LR; Tredway, TL, 1993) |
| " The purpose of this study was to evaluate the ability of pentoxifylline to alter gut cytokine production in a rat model of prolonged acute peritonitis, to determine its effect on survival in such animals, and to determine whether alteration of gut cytokine production was associated with survival." | 3.70 | Effect of pentoxifylline on survival and intestinal cytokine messenger RNA transcription in a rat model of ongoing peritoneal sepsis. ( Alexander, JW; Mao, JX; Nelson, JL; Ogle, CK; Vohs, T, 1999) |
| "The aim of this study was to investigate whether the methylxanthine-derivative pentoxifylline (PTX) affects bacterial clearance of the organism in states of hemorrhage and endotoxemia." | 3.70 | Pentoxifylline improves bacterial clearance during hemorrhage and endotoxemia. ( Heller, A; Heller, S; Koch, T; Urbaschek, R; Weber, K, 1999) |
| "In vivo videomicroscopy was used to quantitate alterations of the small-intestine microcirculation during Escherichia coli bacteremia in rats pretreated with either intravenous pentoxifylline or saline solution." | 3.68 | Pentoxifylline preserves small-intestine microvascular blood flow during bacteremia. ( Garrison, RN; Steeb, GD; Wilson, MA, 1992) |
| "Pentoxifylline treatment reduced lung neutrophil sequestration and IL-1 beta mRNA levels and increased cell recruitment in the peritoneum." | 1.29 | Enhanced survival from cecal ligation and puncture with pentoxifylline is associated with altered neutrophil trafficking and reduced interleukin-1 beta expression but not inhibition of tumor necrosis factor synthesis. ( Cheadle, WG; Hadjiminas, DJ; McMasters, KM; Robertson, SE, 1994) |
| "Since fungal septic shock with acute disseminated candidiasis evolves prior to significant increases in circulating TNF, PTX also appears ineffective in its treatment." | 1.29 | Effects of pentoxifylline on tumor necrosis factor production and survival during lethal E. coli sepsis vs. disseminated candidiasis with fungal septic shock. ( Lechner, AJ; Matuschak, GM; Potthoff, LH; Rouben, LR; Tredway, TL, 1993) |
| "Pentoxifylline was added after incubation of normal cells with patient serum, and the directed chemotaxis was restored." | 1.28 | Pentoxifylline in vitro reverses neutrophil chemotactic deficiency induced by interleukin-2 treatment. ( Fossat, C; Juhan-Vague, I; Maraninchi, D; Sainty, D; Stoppa, AM, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (90.91) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hadjiminas, DJ | 1 |
| McMasters, KM | 1 |
| Robertson, SE | 1 |
| Cheadle, WG | 1 |
| Lechner, AJ | 1 |
| Rouben, LR | 1 |
| Potthoff, LH | 1 |
| Tredway, TL | 1 |
| Matuschak, GM | 1 |
| Krysztopik, RJ | 2 |
| Bentley, FR | 1 |
| Wilson, MA | 3 |
| Spain, DA | 2 |
| Garrison, RN | 3 |
| Vary, TC | 1 |
| Dardevet, D | 1 |
| Obled, C | 1 |
| Pouyet, C | 1 |
| Breuille, D | 1 |
| Grizard, J | 1 |
| Oka, Y | 1 |
| Hasegawa, N | 1 |
| Nakayama, M | 1 |
| Murphy, GA | 1 |
| Sussman, HH | 1 |
| Raffin, TA | 1 |
| Fink, MP | 1 |
| Nelson, JL | 1 |
| Alexander, JW | 1 |
| Mao, JX | 1 |
| Vohs, T | 1 |
| Ogle, CK | 1 |
| Heller, S | 1 |
| Weber, K | 1 |
| Heller, A | 1 |
| Urbaschek, R | 1 |
| Koch, T | 1 |
| Matheson, PJ | 1 |
| Fossat, C | 1 |
| Sainty, D | 1 |
| Stoppa, AM | 1 |
| Maraninchi, D | 1 |
| Juhan-Vague, I | 1 |
| Steeb, GD | 1 |
11 other studies available for pentoxifylline and Bacteremia
| Article | Year |
|---|---|
Enhanced survival from cecal ligation and puncture with pentoxifylline is associated with altered neutrophil trafficking and reduced interleukin-1 beta expression but not inhibition of tumor necrosis factor synthesis.
Topics: Animals; Bacteremia; Cecum; Cell Movement; Disease Models, Animal; Interleukin-1; Ligation; Macropha | 1994 |
Effects of pentoxifylline on tumor necrosis factor production and survival during lethal E. coli sepsis vs. disseminated candidiasis with fungal septic shock.
Topics: Animals; Bacteremia; Candidiasis; Escherichia coli Infections; Fungemia; Gene Expression; Male; Pent | 1993 |
Vasomotor response to pentoxifylline mediates improved renal blood flow to bacteremia.
Topics: Animals; Arterioles; Bacteremia; Blood Pressure; Cardiac Output; Escherichia coli Infections; Heart | 1996 |
Modulation of skeletal muscle lactate metabolism following bacteremia by insulin or insulin-like growth factor-I: effects of pentoxifylline.
Topics: Animals; Bacteremia; Escherichia coli; Insulin; Insulin-Like Growth Factor I; Lactic Acid; Male; Mus | 1997 |
Selective downregulation of neutrophils by a phosphatidic acid generation inhibitor in a porcine sepsis model.
Topics: Actins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacteremia; Cell Adhesion; Disease Models, | 1999 |
Whither pentoxifylline?
Topics: Animals; Bacteremia; Dose-Response Relationship, Drug; Pentoxifylline; Peritonitis; Phosphodiesteras | 1999 |
Effect of pentoxifylline on survival and intestinal cytokine messenger RNA transcription in a rat model of ongoing peritoneal sepsis.
Topics: Animals; Bacteremia; Critical Care; Cytokines; Dietary Proteins; Disease Models, Animal; Dose-Respon | 1999 |
Pentoxifylline improves bacterial clearance during hemorrhage and endotoxemia.
Topics: Animals; Bacteremia; Disease Models, Animal; Drug Evaluation, Preclinical; Endotoxins; Escherichia c | 1999 |
Lazaroid and pentoxifylline suppress sepsis-induced increases in renal vascular resistance via altered arachidonic acid metabolism.
Topics: Animals; Antioxidants; Arachidonic Acid; Bacteremia; Kidney; Male; Pentoxifylline; Phosphodiesterase | 2000 |
Pentoxifylline in vitro reverses neutrophil chemotactic deficiency induced by interleukin-2 treatment.
Topics: Bacteremia; Bone Marrow Transplantation; Cells, Cultured; Chemotaxis, Leukocyte; Disease Susceptibil | 1992 |
Pentoxifylline preserves small-intestine microvascular blood flow during bacteremia.
Topics: Animals; Bacteremia; Blood Pressure; Cardiac Output; Heart Rate; Hemodynamics; Intestinal Mucosa; Is | 1992 |