pentoxifylline has been researched along with B16 Melanoma in 12 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of pentoxifylline on B16 melanoma cell lung colonization, synthesis and properties of glycosaminoglycans (GAGS), and adhesion to and degradation of subendothelial extracellular matrix was examined." | 7.68 | Pentoxifylline enhances lung colonization and alters cell adhesion and glycosaminoglycan synthesis by metastatic B16 melanoma cells. ( Edward, M; MacKie, RM, 1991) |
| "The effect of pentoxifylline on B16 melanoma cell lung colonization, synthesis and properties of glycosaminoglycans (GAGS), and adhesion to and degradation of subendothelial extracellular matrix was examined." | 3.68 | Pentoxifylline enhances lung colonization and alters cell adhesion and glycosaminoglycan synthesis by metastatic B16 melanoma cells. ( Edward, M; MacKie, RM, 1991) |
| "Pentoxifylline has been shown to exhibit anti-metastatic activity by inhibiting homing of B16F10 melanoma cells in the murine experimental metastasis model." | 1.31 | Enhancement of anti-metastatic activity of pentoxifylline by encapsulation in conventional liposomes and sterically stabilized liposomes in murine experimental B16F10 melanoma model. ( Gude, RP; Nagarsenker, MS; Rao, SG; Sant, VP, 2000) |
| " The endothelial cells derived from different sources were inhibited in a dose-response manner by PTX in vitro." | 1.31 | Inhibition of endothelial cell proliferation and tumor-induced angiogenesis by pentoxifylline. ( Binda, MM; Bonfil, RD; Boquete, AL; Gude, RP, 2001) |
| "Adozelesin is a highly potent alkylating agent that undergoes binding in the minor groove of double-stranded DNA (ds-DNA) at A-T-rich sequences followed by covalent bonding with N-3 of adenine in preferred sequences." | 1.29 | Synergistic and additive combinations of several antitumor drugs and other agents with the potent alkylating agent adozelesin. ( Adams, EG; Bhuyan, BK; Folz, BA; Smith, KS, 1995) |
| "B16 melanoma has proved to be an ideal model for investigating metastasis." | 1.29 | Inhibition of lung homing of B16F10 by pentoxifylline, a microfilament depolymerizing agent. ( Gude, RP; Ingle, AD; Rao, SG, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 7 (58.33) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Madera-Sandoval, RL | 1 |
| Tóvári, J | 1 |
| Lövey, J | 1 |
| Ranđelović, I | 1 |
| Jiménez-Orozco, A | 1 |
| Hernández-Chávez, VG | 1 |
| Reyes-Maldonado, E | 1 |
| Vega-López, A | 1 |
| Jain, M | 1 |
| Ratheesh, A | 2 |
| Gude, RP | 9 |
| Shukla, V | 1 |
| Dua, P | 2 |
| Ingle, A | 2 |
| Smith, KS | 1 |
| Folz, BA | 1 |
| Adams, EG | 1 |
| Bhuyan, BK | 1 |
| Ingle, AD | 2 |
| Rao, SG | 2 |
| Gaikwad, SY | 1 |
| Jagtap, AG | 1 |
| Ra, SG | 1 |
| Sant, VP | 1 |
| Nagarsenker, MS | 1 |
| Binda, MM | 1 |
| Boquete, AL | 1 |
| Bonfil, RD | 1 |
| Edward, M | 1 |
| MacKie, RM | 1 |
12 other studies available for pentoxifylline and B16 Melanoma
| Article | Year |
|---|---|
Combination of pentoxifylline and α-galactosylceramide with radiotherapy promotes necro-apoptosis and leukocyte infiltration and reduces the mitosis rate in murine melanoma.
Topics: Animals; Apoptosis; Cell Line, Tumor; Chemoradiotherapy; Galactosylceramides; Leukocytes; Male; Mela | 2019 |
Pentoxifylline inhibits integrin-mediated adherence of 12(S)-HETE and TNFalpha-activated B16F10 cells to fibronectin and endothelial cells.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Antineoplastic Agents; Cell Adhesion; Cell Line | 2010 |
Potentiation of antimetastatic activity of pentoxifylline in B16F10 and B16F1 melanoma cells through inhibition of glutathione content.
Topics: Animals; Cell Line, Tumor; Dose-Response Relationship, Drug; Down-Regulation; Glutathione; Glutathio | 2003 |
Antiproliferative and antiproteolytic activity of pentoxifylline in cultures of B16F10 melanoma cells.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Hydrolysis; Matrix Metalloproteinase 2; Matrix Metall | 2006 |
Suramin augments the antitumor and antimetastatic activity of pentoxifylline in B16F10 melanoma.
Topics: Analysis of Variance; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols | 2007 |
Pentoxifylline modulates cell surface integrin expression and integrin mediated adhesion of B16F10 cells to extracellular matrix components.
Topics: Animals; Cell Adhesion; Cell Line, Tumor; Fibronectins; Integrins; Lung Neoplasms; Melanoma, Experim | 2007 |
Synergistic and additive combinations of several antitumor drugs and other agents with the potent alkylating agent adozelesin.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aphidicolin; Azaciti | 1995 |
Inhibition of lung homing of B16F10 by pentoxifylline, a microfilament depolymerizing agent.
Topics: Actin Cytoskeleton; Animals; Female; Lung Neoplasms; Male; Melanoma, Experimental; Mice; Mice, Inbre | 1996 |
Antimetastatic efficacy of niosomal pentoxifylline and its combination with activated macrophages in murine B16F10 melanoma model.
Topics: Animals; Combined Modality Therapy; Disease Models, Animal; Drug Combinations; Drug Delivery Systems | 2000 |
Enhancement of anti-metastatic activity of pentoxifylline by encapsulation in conventional liposomes and sterically stabilized liposomes in murine experimental B16F10 melanoma model.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Compounding; Female; Liposom | 2000 |
Inhibition of endothelial cell proliferation and tumor-induced angiogenesis by pentoxifylline.
Topics: Angiogenesis Inhibitors; Animals; Endothelium, Vascular; Male; Melanoma, Experimental; Mice; Mice, I | 2001 |
Pentoxifylline enhances lung colonization and alters cell adhesion and glycosaminoglycan synthesis by metastatic B16 melanoma cells.
Topics: Animals; Cell Adhesion; Chondroitin Sulfates; Dendrites; Endothelium, Vascular; Glycosaminoglycans; | 1991 |