pentoxifylline has been researched along with Atrophy in 7 studies
Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.
| Excerpt | Relevance | Reference |
|---|---|---|
| " However, neutralisation of TNF-alpha by an antibody or by pentoxifylline inhibits the occurrence of apoptosis and of mucosal atrophy in this animal model." | 7.70 | Intestinal crypt cell apoptosis in murine acute graft versus host disease is mediated by tumour necrosis factor alpha and not by the FasL-Fas interaction: effect of pentoxifylline on the development of mucosal atrophy. ( Arendt, T; Büschenfeld, A; Fölsch, UR; Stüber, E; von Freier, A, 1999) |
| " However, neutralisation of TNF-alpha by an antibody or by pentoxifylline inhibits the occurrence of apoptosis and of mucosal atrophy in this animal model." | 3.70 | Intestinal crypt cell apoptosis in murine acute graft versus host disease is mediated by tumour necrosis factor alpha and not by the FasL-Fas interaction: effect of pentoxifylline on the development of mucosal atrophy. ( Arendt, T; Büschenfeld, A; Fölsch, UR; Stüber, E; von Freier, A, 1999) |
| "In the future, these treatments of fibrosis and necrosis should include targeted drugs (such as growth factors) to take organ specificities into account." | 2.44 | Current management for late normal tissue injury: radiation-induced fibrosis and necrosis. ( Delanian, S; Lefaix, JL, 2007) |
| "Pentoxifylline is a methylxanthine derivative that produces dose-related hemorrheologic effects, lower blood viscosity, improved erythrocyte flexibility, and increased tissue oxygen levels." | 1.30 | Pentoxifylline in the treatment of radiation-related soft tissue injury: preliminary observations. ( Futran, ND; Gwede, C; Trotti, A, 1997) |
| "Pentoxifylline (Trental) has multiple mechanisms of action, including stimulation of prostacyclin synthesis, decreased aggregation of platelets, increased deformability of red blood cells, increased mobility of neutrophils, and increased fibrinolysis." | 1.27 | Therapy of livedo vasculitis with pentoxifylline. ( Bard, JW; Ely, H, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Patel, V | 1 |
| McGurk, M | 1 |
| Melnik, B | 1 |
| Hariry, H | 1 |
| Vakilzadeh, F | 1 |
| Gropp, C | 1 |
| Sitzer, G | 1 |
| Delanian, S | 1 |
| Lefaix, JL | 1 |
| Futran, ND | 1 |
| Trotti, A | 1 |
| Gwede, C | 1 |
| Stüber, E | 1 |
| Büschenfeld, A | 1 |
| von Freier, A | 1 |
| Arendt, T | 1 |
| Fölsch, UR | 1 |
| Ely, H | 1 |
| Bard, JW | 1 |
| Sauer, GC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Medical Benefit of a Spa Therapy on the Evolutionary Genius of Late Sequelae Fibrosis After Postoperative Radiotherapy for Breast Cancer in Remission[NCT05874492] | 110 participants (Anticipated) | Interventional | 2023-09-30 | Not yet recruiting | |||
| Postoperative or Salvage Radiotherapy for Node Negative Prostate Cancer Following Radical Prostatectomy[NCT00969111] | 70 participants (Anticipated) | Interventional | 2009-08-31 | Recruiting | |||
| An Expanded Phase II Study of Hypofractionated Dose Intense Image Guided Proton Radiation Therapy for Low and Intermediate Risk Adenocarcinoma of the Prostate[NCT01368055] | 361 participants (Actual) | Interventional | 2011-09-30 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for pentoxifylline and Atrophy
| Article | Year |
|---|---|
Use of pentoxifylline and tocopherol in radiation-induced fibrosis and fibroatrophy.
Topics: Antioxidants; Atrophy; Fibrosis; Humans; Pentoxifylline; Radiation Injuries; Radiotherapy; Tocophero | 2017 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
Current management for late normal tissue injury: radiation-induced fibrosis and necrosis.
Topics: Adrenal Cortex Hormones; Antioxidants; Atrophy; Dose-Response Relationship, Radiation; Fibrosis; Hum | 2007 |
5 other studies available for pentoxifylline and Atrophy
| Article | Year |
|---|---|
[Malignant atrophic papulosis (Köhlmeier-Degos disease). Failure to respond to interferon alpha-2a, pentoxifylline and aspirin].
Topics: Aspirin; Atrophy; Connective Tissue; Diagnosis, Differential; Disease Progression; Drug Therapy, Com | 2002 |
Pentoxifylline in the treatment of radiation-related soft tissue injury: preliminary observations.
Topics: Administration, Oral; Aged; Analgesics; Anti-Bacterial Agents; Atrophy; Debridement; Dose-Response R | 1997 |
Intestinal crypt cell apoptosis in murine acute graft versus host disease is mediated by tumour necrosis factor alpha and not by the FasL-Fas interaction: effect of pentoxifylline on the development of mucosal atrophy.
Topics: Animals; Apoptosis; Atrophy; Epithelial Cells; Fas Ligand Protein; Graft vs Host Disease; Intestinal | 1999 |
Therapy of livedo vasculitis with pentoxifylline.
Topics: Adult; Atrophy; Female; Humans; Leg Ulcer; Middle Aged; Pentoxifylline; Skin; Theobromine; Wound Hea | 1988 |
Pentoxifylline (Trental) therapy for the vasculitis of atrophie blanche.
Topics: Adult; Aged; Atrophy; Female; Humans; Leg; Male; Middle Aged; Pentoxifylline; Skin; Skin Diseases; T | 1986 |