Page last updated: 2024-11-02

pentoxifylline and Ataxia Telangiectasia

pentoxifylline has been researched along with Ataxia Telangiectasia in 1 studies

Ataxia Telangiectasia: An autosomal recessive inherited disorder characterized by choreoathetosis beginning in childhood, progressive CEREBELLAR ATAXIA; TELANGIECTASIS of CONJUNCTIVA and SKIN; DYSARTHRIA; B- and T-cell immunodeficiency, and RADIOSENSITIVITY to IONIZING RADIATION. Affected individuals are prone to recurrent sinobronchopulmonary infections, lymphoreticular neoplasms, and other malignancies. Serum ALPHA-FETOPROTEINS are usually elevated. (Menkes, Textbook of Child Neurology, 5th ed, p688) The gene for this disorder (ATM) encodes a cell cycle checkpoint protein kinase and has been mapped to chromosome 11 (11q22-q23).

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sarkaria, JN1
Eshleman, JS1

Reviews

1 review available for pentoxifylline and Ataxia Telangiectasia

ArticleYear
ATM as a target for novel radiosensitizers.
    Seminars in radiation oncology, 2001, Volume: 11, Issue:4

    Topics: Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Caffeine; Cell Cycle; Cell Cycle Prot

2001