pentoxifylline has been researched along with Arthritis, Rheumatoid in 10 studies
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Under the conditions of our trial, the therapeutic benefits provided by pentoxifylline were too small to warrant use of this drug in severe refractory rheumatoid arthritis." | 9.08 | An open study of the anti-TNF alpha agent pentoxifylline in the treatment of rheumatoid arthritis. ( Beaujon, G; Bussière, JL; Dubost, JJ; Oualid, T; Ristori, JM; Sauvezie, B; Soubrier, M, 1997) |
| "12 patients with active rheumatoid arthritis were treated with 1200 mg pentoxifylline and 100 mg thalidomide a day during 12 weeks." | 7.69 | An open study of pentoxyfylline and thalidomide as adjuvant therapy in the treatment of rheumatoid arthritis. ( Breedveld, FC; Dijkmans, BA; Huizinga, TW; van de Pouw Kraan, TC; van der Velde, EA; Verweij, CL, 1996) |
| "Pentoxifylline was also reported to possess therapeutic properties in 50% of severe refractory RA in an open study." | 5.30 | [Remission induction after pentoxifylline treatment in a patient with rheumatoid arthritis]. ( Ichikawa, Y; Ishii, O; Kase, C; Moriuchi, E; Ohya, S; Yamada, H; Yamasaki, K, 1997) |
| "Under the conditions of our trial, the therapeutic benefits provided by pentoxifylline were too small to warrant use of this drug in severe refractory rheumatoid arthritis." | 5.08 | An open study of the anti-TNF alpha agent pentoxifylline in the treatment of rheumatoid arthritis. ( Beaujon, G; Bussière, JL; Dubost, JJ; Oualid, T; Ristori, JM; Sauvezie, B; Soubrier, M, 1997) |
| "12 patients with active rheumatoid arthritis were treated with 1200 mg pentoxifylline and 100 mg thalidomide a day during 12 weeks." | 3.69 | An open study of pentoxyfylline and thalidomide as adjuvant therapy in the treatment of rheumatoid arthritis. ( Breedveld, FC; Dijkmans, BA; Huizinga, TW; van de Pouw Kraan, TC; van der Velde, EA; Verweij, CL, 1996) |
| "Concomitantly to AIA, mice presented alveolar bone loss, and recruitment of osteoclasts and neutrophils to periodontal tissues." | 1.39 | Preventive and therapeutic anti-TNF-α therapy with pentoxifylline decreases arthritis and the associated periodontal co-morbidity in mice. ( Bessoni, RL; Costa, VV; Queiroz-Junior, CM; Silva, TA; Souza, DG; Teixeira, MM, 2013) |
| "Pentoxifylline was also reported to possess therapeutic properties in 50% of severe refractory RA in an open study." | 1.30 | [Remission induction after pentoxifylline treatment in a patient with rheumatoid arthritis]. ( Ichikawa, Y; Ishii, O; Kase, C; Moriuchi, E; Ohya, S; Yamada, H; Yamasaki, K, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (70.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Queiroz-Junior, CM | 1 |
| Bessoni, RL | 1 |
| Costa, VV | 1 |
| Souza, DG | 1 |
| Teixeira, MM | 1 |
| Silva, TA | 1 |
| Anaya, JM | 1 |
| Espinoza, LR | 1 |
| Maksymowych, WP | 1 |
| Avina-Zubieta, A | 1 |
| Luong, MH | 1 |
| Russell, AS | 1 |
| Huizinga, TW | 1 |
| Dijkmans, BA | 1 |
| van der Velde, EA | 1 |
| van de Pouw Kraan, TC | 1 |
| Verweij, CL | 1 |
| Breedveld, FC | 1 |
| Dubost, JJ | 1 |
| Soubrier, M | 1 |
| Ristori, JM | 1 |
| Beaujon, G | 1 |
| Oualid, T | 1 |
| Bussière, JL | 1 |
| Sauvezie, B | 1 |
| Ishii, O | 1 |
| Yamada, H | 1 |
| Ohya, S | 1 |
| Moriuchi, E | 1 |
| Kase, C | 1 |
| Ichikawa, Y | 1 |
| Yamasaki, K | 1 |
| Kiely, PD | 1 |
| Johnson, D | 1 |
| Bourke, BE | 1 |
| Wendling, D | 1 |
| Toussirot, E | 1 |
| Raza, A | 1 |
| Smolian, H | 1 |
| Aurer, A | 1 |
| Sittinger, M | 1 |
| Zacher, J | 1 |
| Bernimoulin, JP | 1 |
| Burmester, GR | 1 |
| Kolkenbrock, H | 1 |
2 reviews available for pentoxifylline and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Phosphodiesterase inhibitor pentoxifylline: an antiinflammatory/immunomodulatory drug potentially useful in some rheumatic diseases.
Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Hum | 1995 |
Anti-TNF therapies in rheumatoid arthritis, Crohn's disease, sepsis, and myelodysplastic syndromes.
Topics: Arthritis, Rheumatoid; Crohn Disease; Etanercept; Humans; Immunoglobulin G; Myelodysplastic Syndrome | 2000 |
3 trials available for pentoxifylline and Arthritis, Rheumatoid
| Article | Year |
|---|---|
An open study of pentoxifylline in the treatment of severe refractory rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Sedimentation; Enzyme-Linked Immunosorbent Assay; Female; | 1995 |
An open study of the anti-TNF alpha agent pentoxifylline in the treatment of rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Outcome Assessment, | 1997 |
An open study of oxpentifylline in early rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Pentoxifylline; Phosphodieste | 1998 |
5 other studies available for pentoxifylline and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Preventive and therapeutic anti-TNF-α therapy with pentoxifylline decreases arthritis and the associated periodontal co-morbidity in mice.
Topics: Alveolar Bone Loss; Animals; Antigens; Arthritis, Experimental; Arthritis, Rheumatoid; C-Reactive Pr | 2013 |
An open study of pentoxyfylline and thalidomide as adjuvant therapy in the treatment of rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Chemotherapy, Adjuvant; Hematologic Tests; Humans; Immu | 1996 |
[Remission induction after pentoxifylline treatment in a patient with rheumatoid arthritis].
Topics: Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Drug Therapy, Combination; Hu | 1997 |
TNF-alpha-targeted therapy in rheumatoid arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Arthritis, Rheumatoid; Dru | 1999 |
Secretion of gelatinases and activation of gelatinase A (MMP-2) by human rheumatoid synovial fibroblasts.
Topics: Arthritis, Rheumatoid; Concanavalin A; Cyclic CMP; Cytochalasin D; Enzyme Activation; Enzyme Inhibit | 2001 |