Page last updated: 2024-11-02

pentoxifylline and Angiitis

pentoxifylline has been researched along with Angiitis in 16 studies

Research Excerpts

ExcerptRelevanceReference
"Eight patients with livedo vasculitis of four to 30 years' duration that was unresponsive to a variety of medications were treated with pentoxifylline."7.67Livedo vasculitis. Therapy with pentoxifylline. ( Sams, WM, 1988)
"Pentoxifylline has been used to treat various dermatological conditions including peripheral vascular disease, vasculitis and vasculopathies, chilblains, pigmented purpuric dermatosis, granuloma annulare, necrobiosis, keloids, lichen sclerosis et atrophicus, scars, radiation-induced fibrosis, vitiligo, alopecia areata, leishmaniasis, and leprosy."5.41Pentoxifylline in dermatology. ( Axler, E; Balazic, E; Khanna, U; Kobets, K; Konisky, H, 2023)
"Eight patients with livedo vasculitis of four to 30 years' duration that was unresponsive to a variety of medications were treated with pentoxifylline."3.67Livedo vasculitis. Therapy with pentoxifylline. ( Sams, WM, 1988)
"Livedoid vasculitis is a painful ulcerative condition affecting the legs that is often difficult to treat."1.32Clinical profile and treatment outcome of livedoid vasculitis: a case series. ( Ang, P; Lee, SS; Tan, SH, 2003)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19904 (25.00)18.7374
1990's3 (18.75)18.2507
2000's3 (18.75)29.6817
2010's5 (31.25)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Balazic, E1
Axler, E1
Konisky, H1
Khanna, U1
Kobets, K1
Gupta, SK2
Mi, D1
Dubé, MP2
Saha, CK1
Johnson, RM1
Stein, JH2
Clauss, MA2
Mather, KJ1
Desta, Z1
Liu, Z2
Jenkins, J1
Babu, K1
Hsu-Hung, E1
Robinson-Bostom, L1
Kroumpouzos, G1
Pua, U1
Spriggs, M1
Reeder, C1
Lee, SS1
Ang, P1
Tan, SH1
Shibata, S1
Yamada, A1
Miyagawa, Y1
Kiely, PD1
Gillespie, KM1
Oliveira, DB1
Zabel, P1
Goodfield, M1
Souza, CS1
Roselino, AM1
Figueiredo, F1
Foss, NT1
Hegemann, B1
Helmbold, P1
Marsch, WC1
Sams, WM1
Sauer, GC2

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Placebo-Controlled Trial of Pentoxifylline to Improve Endothelial Function in HIV-Infected Patients Not Requiring Antiretroviral Therapy[NCT00796822]Phase 226 participants (Actual)Interventional2009-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Flow-mediated Dilation of the Brachial Artery

Flow-mediated dilation is nn in vivo measure of arterial endothelial function. We assessed changes in flow-mediated dilation from baseline to week 8. (NCT00796822)
Timeframe: Measured at baseline and Week 8

Interventionabsolute percentage (Mean)
Pentoxifylline-1.93
Placebo-1.06

Change in Soluble TNF-Receptor I Levels

Measure of systemic inflammation (NCT00796822)
Timeframe: Measured at baseline and Week 8

Interventionpg/mL (Mean)
Pentoxifylline65.9
Placebo-83.2

Reviews

3 reviews available for pentoxifylline and Angiitis

ArticleYear
Pentoxifylline in dermatology.
    Journal of cosmetic dermatology, 2023, Volume: 22, Issue:2

    Topics: Cicatrix; Granuloma Annulare; Humans; Intermittent Claudication; Pentoxifylline; Vasculitis

2023
[Pathogenesis of interstitial pulmonary changes with collagen diseases--therapeutic implications].
    Immunitat und Infektion, 1995, Volume: 23, Issue:3

    Topics: Adrenal Cortex Hormones; Antigen-Antibody Complex; Antimetabolites; Autoantibodies; Autoantigens; Au

1995
Optimal management of chronic leg ulcers in the elderly.
    Drugs & aging, 1997, Volume: 10, Issue:5

    Topics: Administration, Oral; Aged; Aging; Arterial Occlusive Diseases; Aspirin; Bandages; Combined Modality

1997

Trials

2 trials available for pentoxifylline and Angiitis

ArticleYear
Pentoxifylline, inflammation, and endothelial function in HIV-infected persons: a randomized, placebo-controlled trial.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Adult; Antiretroviral Therapy, Highly Active; Biomarkers; Endothelium, Vascular; Female; HIV Infecti

2013
A pilot trial of pentoxifylline on endothelial function and inflammation in HIV-infected patients initiating antiretroviral therapy.
    AIDS (London, England), 2016, 08-24, Volume: 30, Issue:13

    Topics: Adult; Antiretroviral Therapy, Highly Active; Biomarkers; Endothelium, Vascular; Female; HIV Infecti

2016

Other Studies

11 other studies available for pentoxifylline and Angiitis

ArticleYear
ANCA-positive necrotizing vasculitis and thrombotic vasculopathy induced by levamisole-adulterated cocaine: a distinctive clinicopathologic presentation.
    Journal of the American Academy of Dermatology, 2011, Volume: 65, Issue:1

    Topics: Adrenal Cortex Hormones; Antibodies, Antineutrophil Cytoplasmic; Aspirin; Biopsy, Needle; Cocaine-Re

2011
Hand angiography in connective tissue disease.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2012, Volume: 18, Issue:6

    Topics: Adult; Angiography; Arterial Occlusive Diseases; Contrast Media; Female; Hand; Humans; Mixed Connect

2012
Treatment of vasculitis and dermatitis in a 59-yr-old Nile hippopotamus (Hippopotamus amphibius).
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2012, Volume: 43, Issue:3

    Topics: Animal Husbandry; Animals; Animals, Zoo; Anti-Bacterial Agents; Artiodactyla; Female; Pentoxifylline

2012
Clinical profile and treatment outcome of livedoid vasculitis: a case series.
    Annals of the Academy of Medicine, Singapore, 2003, Volume: 32, Issue:6

    Topics: Adult; Aspirin; Colchicine; Drug Therapy, Combination; Gout Suppressants; Humans; Male; Middle Aged;

2003
[Effects of pentoxifylline (Trental) on peripheral circulatory disorders in collagen and related diseases].
    Nihon rinsho. Japanese journal of clinical medicine, 1980, Volume: 38, Issue:11

    Topics: Adult; Collagen Diseases; Female; Humans; Lupus Erythematosus, Systemic; Male; Pentoxifylline; Theob

1980
Oxpentifylline inhibits tumor necrosis factor-alpha mRNA transcription and protects against arthritis in mercuric chloride-treated brown Norway rats.
    European journal of immunology, 1995, Volume: 25, Issue:10

    Topics: Animals; Arthritis; Autoimmune Diseases; Cecal Diseases; Disease Models, Animal; Humans; Immunoglobu

1995
Lucio's phenomenon: clinical and therapeutic aspects.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 2000, Volume: 68, Issue:4

    Topics: Aged; Anti-Inflammatory Agents; Brazil; Disease Progression; Endothelium, Vascular; Fatal Outcome; F

2000
Livedoid vasculitis with ulcerations: the role of antithrombin III deficiency and its therapeutic consequences.
    Archives of dermatology, 2002, Volume: 138, Issue:6

    Topics: Antithrombin III Deficiency; Female; Follow-Up Studies; Foot Ulcer; Humans; Male; Middle Aged; Pento

2002
Livedo vasculitis. Therapy with pentoxifylline.
    Archives of dermatology, 1988, Volume: 124, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Dipyridamole; Drug Therapy, Combination; Female; Humans; Ma

1988
Pentoxifylline (Trental) therapy for the vasculitis of atrophie blanche.
    Archives of dermatology, 1986, Volume: 122, Issue:4

    Topics: Adult; Aged; Atrophy; Female; Humans; Leg; Male; Middle Aged; Pentoxifylline; Skin; Skin Diseases; T

1986
Pentoxifylline (Trental) therapy for vasculitis of pityriasis lichenoides et varioliformis.
    Archives of dermatology, 1985, Volume: 121, Issue:12

    Topics: Administration, Oral; Adult; Aged; Female; Humans; Pentoxifylline; Pityriasis; Theobromine; Vasculit

1985