pentoxifylline has been researched along with Amyotrophic Lateral Sclerosis in 4 studies
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gordon, PH | 1 |
| Corcia, P | 1 |
| Lacomblez, L | 2 |
| Pochigaeva, K | 1 |
| Abitbol, JL | 1 |
| Cudkowicz, M | 2 |
| Leigh, PN | 2 |
| Meininger, V | 2 |
| Asselain, B | 1 |
| Guillet, P | 1 |
| Ludolph, A | 1 |
| Robberecht, W | 1 |
| Levin, BJ | 1 |
| Thompson, G | 1 |
| Mitsumoto, LH | 1 |
| Kaufmann, P | 1 |
| Lindhorst, S | 1 |
1 review available for pentoxifylline and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Defining survival as an outcome measure in amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Clinical Trials as Topic; Endpoint Determination; Humans; Kaplan-Meie | 2009 |
1 trial available for pentoxifylline and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Pentoxifylline in ALS: a double-blind, randomized, multicenter, placebo-controlled trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Double-Blind Method; Drug | 2006 |
2 other studies available for pentoxifylline and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Pentoxifylline in ALS: a double-blind, randomized, multicenter, placebo-controlled trial.
Topics: Amyotrophic Lateral Sclerosis; Data Interpretation, Statistical; Double-Blind Method; Humans; Multic | 2006 |
Is pentoxifylline safe and effective in patients with amyotrophic lateral sclerosis?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Double-Blind Method; Fema | 2006 |