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pentoxifylline and Allergic Encephalomyelitis

pentoxifylline has been researched along with Allergic Encephalomyelitis in 9 studies

Research Excerpts

ExcerptRelevanceReference
"The effect of pentoxifylline (PTX) on experimental allergic encephalomyelitis (EAE) in mice, a known animal model of multiple sclerosis (MS), was investigated."7.69Pentoxifylline delays the onset of experimental allergic encephalomyelitis in mice by modulating cytokine production in peripheral blood mononuclear cells. ( Fujimura, H; Okuda, Y; Sakoda, S; Yanagihara, T, 1996)
"Experimental allergic encephalomyelitis (EAE) is an inflammatory, CD4+ Th1-mediated autoimmune disease, which serves as a model for multiple sclerosis."5.30Prevention of experimental allergic encephalomyelitis via inhibition of IL-12 signaling and IL-12-mediated Th1 differentiation: an effect of the novel anti-inflammatory drug lisofylline. ( Bright, JJ; Coon, M; Du, C; Klaus, SJ; Sriram, S, 1998)
"The pentoxifylline treated rats showed a significantly lower incidence of clinical signs as well as significantly lower histological inflammation."5.29Pentoxifylline inhibits experimental allergic encephalomyelitis. ( Chabannes, D; Fève, JR; Louboutin, JP; Muller, JY; Nataf, S, 1993)
"Experimental allergic encephalomyelitis (EAE) is an inflammatory, CD4+ Th1-mediated autoimmune disease, which serves as a model for multiple sclerosis."1.30Prevention of experimental allergic encephalomyelitis via inhibition of IL-12 signaling and IL-12-mediated Th1 differentiation: an effect of the novel anti-inflammatory drug lisofylline. ( Bright, JJ; Coon, M; Du, C; Klaus, SJ; Sriram, S, 1998)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (55.56)18.2507
2000's3 (33.33)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Corrêa, JO1
Aarestrup, BJ1
Aarestrup, FM1
Pollak, Y1
Ovadia, H1
Orion, E1
Yirmiya, R1
Nataf, S1
Louboutin, JP1
Chabannes, D1
Fève, JR1
Muller, JY1
Rott, O1
Cash, E1
Fleischer, B1
Okuda, Y1
Sakoda, S1
Fujimura, H1
Yanagihara, T1
Clements, JM1
Cossins, JA1
Wells, GM1
Corkill, DJ1
Helfrich, K1
Wood, LM1
Pigott, R1
Stabler, G1
Ward, GA1
Gearing, AJ1
Miller, KM1
Bright, JJ2
Du, C2
Coon, M1
Sriram, S3
Klaus, SJ2
Cooper, JC1

Reviews

1 review available for pentoxifylline and Allergic Encephalomyelitis

ArticleYear
Immunotherapy of inflammatory demyelinating diseases of the central nervous system.
    Immunologic research, 2001, Volume: 23, Issue:2-3

    Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; CD4-Positive T-Lymphocytes; Cerebrospinal F

2001

Other Studies

8 other studies available for pentoxifylline and Allergic Encephalomyelitis

ArticleYear
Effect of thalidomide and pentoxifylline on experimental autoimmune encephalomyelitis (EAE).
    Experimental neurology, 2010, Volume: 226, Issue:1

    Topics: Animals; Brain; Encephalomyelitis, Autoimmune, Experimental; Female; Guinea Pigs; Immunosuppressive

2010
The EAE-associated behavioral syndrome: II. Modulation by anti-inflammatory treatments.
    Journal of neuroimmunology, 2003, Volume: 137, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents; Behavior, Animal; Dexamethasone; Encephalomyelitis, Autoimmune, E

2003
Pentoxifylline inhibits experimental allergic encephalomyelitis.
    Acta neurologica Scandinavica, 1993, Volume: 88, Issue:2

    Topics: Animals; Blood-Brain Barrier; Cytokines; Encephalomyelitis, Autoimmune, Experimental; Female; Macrop

1993
Phosphodiesterase inhibitor pentoxifylline, a selective suppressor of T helper type 1- but not type 2-associated lymphokine production, prevents induction of experimental autoimmune encephalomyelitis in Lewis rats.
    European journal of immunology, 1993, Volume: 23, Issue:8

    Topics: Animals; Bucladesine; Encephalomyelitis, Autoimmune, Experimental; Female; Immunosuppressive Agents;

1993
Pentoxifylline delays the onset of experimental allergic encephalomyelitis in mice by modulating cytokine production in peripheral blood mononuclear cells.
    Immunopharmacology, 1996, Volume: 35, Issue:2

    Topics: Animals; Cytokines; Encephalomyelitis, Autoimmune, Experimental; Female; Interleukin-1; Interleukin-

1996
Matrix metalloproteinase expression during experimental autoimmune encephalomyelitis and effects of a combined matrix metalloproteinase and tumour necrosis factor-alpha inhibitor.
    Journal of neuroimmunology, 1997, Volume: 74, Issue:1-2

    Topics: Animals; Benzyl Compounds; Dexamethasone; Drug Combinations; Encephalomyelitis, Autoimmune, Experime

1997
Prevention of experimental allergic encephalomyelitis via inhibition of IL-12 signaling and IL-12-mediated Th1 differentiation: an effect of the novel anti-inflammatory drug lisofylline.
    Journal of immunology (Baltimore, Md. : 1950), 1998, Dec-15, Volume: 161, Issue:12

    Topics: Adoptive Transfer; Animals; Anti-Inflammatory Agents, Non-Steroidal; Autoimmune Diseases; Cell Diffe

1998
Amelioration of CR-EAE with lisofylline: effects on mRNA levels of IL-12 and IFN-gamma in the CNS.
    Journal of neuroimmunology, 2000, Oct-02, Volume: 110, Issue:1-2

    Topics: Animals; Central Nervous System; Encephalomyelitis, Autoimmune, Experimental; Female; Gene Expressio

2000