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pentoxifylline and Aging

pentoxifylline has been researched along with Aging in 13 studies

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"Morris water maze test was used to observe the effects of pentoxifylline on learning and memory of naturally aging rats, and jumping stand test was performed to examine its effects in promoting the learning and memory functions in mice with scopolamine- and ethanol-induced memory dysfunctions."7.74[Pentoxifylline promotes learning and memory function of aging rats and mice with induced memory impairment]. ( Chen, D; Hu, R; Kang, J; Su, LZ; Wei, XZ; Yuan, BX; Zhao, LM, 2007)
"Morris water maze test was used to observe the effects of pentoxifylline on learning and memory of naturally aging rats, and jumping stand test was performed to examine its effects in promoting the learning and memory functions in mice with scopolamine- and ethanol-induced memory dysfunctions."3.74[Pentoxifylline promotes learning and memory function of aging rats and mice with induced memory impairment]. ( Chen, D; Hu, R; Kang, J; Su, LZ; Wei, XZ; Yuan, BX; Zhao, LM, 2007)
"Pentoxifylline (PTX) is a non-specific phosphodiesterase inhibitor with pleiotropic effects that is routinely used to treat peripheral vascular disease."1.56Pentoxifylline enhances antioxidative capability and promotes mitochondrial biogenesis for improving age-related behavioral deficits. ( Cui, R; Huang, Y; Ji, X; Kang, Y; Qi, C; Shi, G; Wang, Y; Yan, W; Zhang, G; Zhang, T; Zhao, H, 2020)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19903 (23.08)18.7374
1990's6 (46.15)18.2507
2000's1 (7.69)29.6817
2010's2 (15.38)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Wang, Y1
Kang, Y1
Qi, C1
Zhang, T1
Zhao, H1
Ji, X1
Yan, W1
Huang, Y1
Cui, R1
Zhang, G1
Shi, G1
Speer, EM1
Dowling, DJ1
Xu, J1
Ozog, LS1
Mathew, JA1
Chander, A1
Yin, D1
Levy, O1
Pozor, M1
Freeman, D1
Troedsson, M1
Brown, M1
Morton, A1
Smith, A1
McNaughten, J1
Hu, R1
Yuan, BX1
Su, LZ1
Wei, XZ1
Zhao, LM1
Kang, J1
Chen, D1
de Toledo-Morrell, L2
Morrell, F2
Fleming, S1
Cohen, MM1
Ungemach, FR1
Pridjian, AK1
Bove, EL1
Bolling, SF1
Childs, KF1
Brosamer, KM1
Lupinetti, FM1
Tortorella, C1
Polignano, A1
Piazzolla, G1
Serrone, M1
Jirillo, E1
Antonaci, S1
Goodfield, M1
Raj, JU2
Kaapa, P2
Anderson, J2
Ibe, BO1
Parnetti, L1
Ciuffetti, G1
Mercuri, M1
Lupattelli, G1
Senin, U1

Reviews

1 review available for pentoxifylline and Aging

ArticleYear
Optimal management of chronic leg ulcers in the elderly.
    Drugs & aging, 1997, Volume: 10, Issue:5

    Topics: Administration, Oral; Aged; Aging; Arterial Occlusive Diseases; Aspirin; Bandages; Combined Modality

1997

Trials

1 trial available for pentoxifylline and Aging

ArticleYear
The role of haemorheological factors in the ageing brain: long-term therapy with pentoxifylline ('Trental' 400) in elderly patients with initial mental deterioration.
    Pharmatherapeutica, 1986, Volume: 4, Issue:10

    Topics: Aged; Aging; Blood Viscosity; Cerebrovascular Circulation; Dementia; Erythrocyte Deformability; Fema

1986

Other Studies

11 other studies available for pentoxifylline and Aging

ArticleYear
Pentoxifylline enhances antioxidative capability and promotes mitochondrial biogenesis for improving age-related behavioral deficits.
    Aging, 2020, 11-20, Volume: 12, Issue:24

    Topics: Aging; Animals; Antioxidants; Behavior, Animal; Brain; Male; Maze Learning; Mitochondria; Organelle

2020
Pentoxifylline, dexamethasone and azithromycin demonstrate distinct age-dependent and synergistic inhibition of TLR- and inflammasome-mediated cytokine production in human newborn and adult blood in vitro.
    PloS one, 2018, Volume: 13, Issue:5

    Topics: Adolescent; Adult; Aging; Anti-Inflammatory Agents; Azithromycin; Caspase 1; Cytokines; Dexamethason

2018
Anatomical variations in epididymal-testicular fusion in stallions and their possible clinical significance.
    Equine veterinary journal, 2016, Volume: 48, Issue:4

    Topics: Aging; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Epididymis

2016
[Pentoxifylline promotes learning and memory function of aging rats and mice with induced memory impairment].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2007, Volume: 27, Issue:11

    Topics: Aging; Animals; Behavior, Animal; Ethanol; Maze Learning; Memory; Memory Disorders; Mice; Pentoxifyl

2007
Pentoxifylline reverses age-related deficits in spatial memory.
    Behavioral and neural biology, 1984, Volume: 42, Issue:1

    Topics: Aging; Animals; Choline; Cues; Discrimination Learning; Male; Memory; Mental Recall; Orientation; Pe

1984
[Geriatric drugs in aged dogs?].
    Tierarztliche Praxis, 1994, Volume: 22, Issue:3

    Topics: Aging; Animals; Cerebral Hemorrhage; Dog Diseases; Dogs; Hemorrhage; Hormones; Pentoxifylline; Proca

1994
Developmental differences in myocardial protection in response to 5'-nucleotidase inhibition.
    The Journal of thoracic and cardiovascular surgery, 1994, Volume: 107, Issue:2

    Topics: 5'-Nucleotidase; Aging; Animals; Animals, Newborn; Bicarbonates; Calcium Chloride; Cardiac Output; C

1994
Lipopolysaccharide-, granulocyte-monocyte colony stimulating factor and pentoxifylline-mediated effects on formyl-methionyl-leucine-phenylalanine-stimulated neutrophil respiratory burst in the elderly.
    Microbios, 1996, Volume: 85, Issue:344

    Topics: Aged; Aged, 80 and over; Aging; Cells, Cultured; Female; Granulocyte-Macrophage Colony-Stimulating F

1996
Age-related differences in vascular effects of pentoxifylline in isolated perfused ferret lungs.
    Developmental pharmacology and therapeutics, 1992, Volume: 18, Issue:1-2

    Topics: Aging; Animals; Animals, Newborn; Ferrets; Hydrogen-Ion Concentration; Pentoxifylline; Pulmonary Cir

1992
Effect of pentoxifylline in rabbit pulmonary circulation: influence of age and vasomotor tone.
    The American journal of physiology, 1991, Volume: 261, Issue:4 Pt 2

    Topics: Aging; Animals; Epoprostenol; Indomethacin; Papaverine; Pentoxifylline; Potassium Chloride; Prostagl

1991
Electrophysiological markers of aging and memory loss in rats.
    Annals of the New York Academy of Sciences, 1985, Volume: 444

    Topics: Aging; Animals; Brain; Choline; Discrimination Learning; Electroencephalography; Hippocampus; Kindli

1985