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pentoxifylline and Age-Related Memory Disorders

pentoxifylline has been researched along with Age-Related Memory Disorders in 6 studies

Research Excerpts

ExcerptRelevanceReference
"The current studies were aimed at evaluating the efficacy of intranasal pentoxifylline (Ptx) pretreatment in protecting mesodopaminergic system and hippocampus from oxidative damage of lithium-pilocarpine induced status epilepticus (SE) and the involvement of nuclear factor erythroid 2-related factor 2- (Nrf2-) antioxidant response elements pathway."7.85Alleviation of Oxidative Damage and Involvement of Nrf2-ARE Pathway in Mesodopaminergic System and Hippocampus of Status Epilepticus Rats Pretreated by Intranasal Pentoxifylline. ( Cui, H; Du, Y; Fang, H; Kang, Y; Shi, G; Wang, L; Yan, W; Zhang, G, 2017)
"Morris water maze test was used to observe the effects of pentoxifylline on learning and memory of naturally aging rats, and jumping stand test was performed to examine its effects in promoting the learning and memory functions in mice with scopolamine- and ethanol-induced memory dysfunctions."7.74[Pentoxifylline promotes learning and memory function of aging rats and mice with induced memory impairment]. ( Chen, D; Hu, R; Kang, J; Su, LZ; Wei, XZ; Yuan, BX; Zhao, LM, 2007)
"The results of a comparative clinical study with pentoxifylline -- a new vasoactive compound -- and xanthinol nicotinate in fifty-eight patients suffering from cerebral thrombosis with hemiplegia or monoplegia, are presented."5.05Pentoxifylline in strokes: a clinical study. ( Janaki, S, 1980)
"The current studies were aimed at evaluating the efficacy of intranasal pentoxifylline (Ptx) pretreatment in protecting mesodopaminergic system and hippocampus from oxidative damage of lithium-pilocarpine induced status epilepticus (SE) and the involvement of nuclear factor erythroid 2-related factor 2- (Nrf2-) antioxidant response elements pathway."3.85Alleviation of Oxidative Damage and Involvement of Nrf2-ARE Pathway in Mesodopaminergic System and Hippocampus of Status Epilepticus Rats Pretreated by Intranasal Pentoxifylline. ( Cui, H; Du, Y; Fang, H; Kang, Y; Shi, G; Wang, L; Yan, W; Zhang, G, 2017)
"Morris water maze test was used to observe the effects of pentoxifylline on learning and memory of naturally aging rats, and jumping stand test was performed to examine its effects in promoting the learning and memory functions in mice with scopolamine- and ethanol-induced memory dysfunctions."3.74[Pentoxifylline promotes learning and memory function of aging rats and mice with induced memory impairment]. ( Chen, D; Hu, R; Kang, J; Su, LZ; Wei, XZ; Yuan, BX; Zhao, LM, 2007)
") also potentiates oxotremorine-induced tremors in mice, in a dose-dependent manner, and this effect was completely prevented by atropine."3.71Evidence for the involvement of the muscarinic cholinergic system in the central actions of pentoxifylline. ( Cunha, GM; Farias, PA; Viana, GS, 2002)
"Pentoxifylline (PTX) is a potent antioxidant, which has an important role in prevention of cognitive dysfunctions."1.48Pentoxifylline prevents post-traumatic stress disorder induced memory impairment. ( Ahmed, M; Alzoubi, KH; Khabour, OF, 2018)
"The results show that chronic sleep deprivation impaired short- and long-term memories, which was prevented by chronic treatment with PTX."1.39Evaluation of the effect of pentoxifylline on sleep-deprivation induced memory impairment. ( Al-Azzam, SI; Alzoubi, KH; Khabour, OF; Mhaidat, NM; Tashtoush, NH, 2013)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19901 (16.67)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kang, Y1
Yan, W1
Fang, H1
Zhang, G1
Du, Y1
Wang, L1
Cui, H1
Shi, G1
Alzoubi, KH2
Khabour, OF2
Ahmed, M1
Tashtoush, NH1
Al-Azzam, SI1
Mhaidat, NM1
Hu, R1
Yuan, BX1
Su, LZ1
Wei, XZ1
Zhao, LM1
Kang, J1
Chen, D1
Janaki, S1
Cunha, GM1
Farias, PA1
Viana, GS1

Trials

1 trial available for pentoxifylline and Age-Related Memory Disorders

ArticleYear
Pentoxifylline in strokes: a clinical study.
    The Journal of international medical research, 1980, Volume: 8, Issue:1

    Topics: Adult; Blood Pressure; Drug Evaluation; Female; Hemiplegia; Humans; Intelligence; Intracranial Embol

1980

Other Studies

5 other studies available for pentoxifylline and Age-Related Memory Disorders

ArticleYear
Alleviation of Oxidative Damage and Involvement of Nrf2-ARE Pathway in Mesodopaminergic System and Hippocampus of Status Epilepticus Rats Pretreated by Intranasal Pentoxifylline.
    Oxidative medicine and cellular longevity, 2017, Volume: 2017

    Topics: Administration, Intranasal; Animals; Anticonvulsants; Blotting, Western; Dopamine Agents; Hippocampu

2017
Pentoxifylline prevents post-traumatic stress disorder induced memory impairment.
    Brain research bulletin, 2018, Volume: 139

    Topics: Animals; Brain-Derived Neurotrophic Factor; Catalase; Disease Models, Animal; Free Radical Scavenger

2018
Evaluation of the effect of pentoxifylline on sleep-deprivation induced memory impairment.
    Hippocampus, 2013, Volume: 23, Issue:9

    Topics: Analysis of Variance; Animals; Calorimetry; Catalase; Disease Models, Animal; Glutathione; Glutathio

2013
[Pentoxifylline promotes learning and memory function of aging rats and mice with induced memory impairment].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2007, Volume: 27, Issue:11

    Topics: Aging; Animals; Behavior, Animal; Ethanol; Maze Learning; Memory; Memory Disorders; Mice; Pentoxifyl

2007
Evidence for the involvement of the muscarinic cholinergic system in the central actions of pentoxifylline.
    Behavioural pharmacology, 2002, Volume: 13, Issue:2

    Topics: Acetylcholinesterase; Animals; Anxiety; Avoidance Learning; Hippocampus; Learning Disabilities; Male

2002