pentoxifylline has been researched along with Acute Kidney Failure in 32 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the nephro-protective effects of berberine and/or pentoxifylline on the reduction of diclofenac-induced acute kidney injury in rats." | 7.91 | Berberine and Pentoxifylline: A novel combination in amelioration of acute kidney injury. ( Al-Gareeb, AI; Al-Kuraishy, HM; Hussien, NR, 2019) |
| "Pentoxifylline has been shown to improve tissue oxygenation and endothelial function and inhibit proinflammatory cytokine production." | 5.35 | Pentoxifylline in ischemia-induced acute kidney injury in rats. ( Martinelli, R; Okumura, AS; Rodrigues, LE, 2009) |
| "Participants in the Steroids or Pentoxifylline for Alcoholic Hepatitis trial with day zero (D0) creatinine available were included." | 4.31 | In severe alcohol-related hepatitis, acute kidney injury is prevalent, associated with mortality independent of liver disease severity, and can be predicted using IL-8 and micro-RNAs. ( Allison, M; Atkinson, S; Austin, A; Dear, JW; Forrest, E; Hunter, RW; Liu, T; Lord, E; Masson, S; Nunes, J; Richardson, P; Ryder, SD; Thursz, M; Tyson, LD; Vergis, N; Wright, M, 2023) |
| "To evaluate the nephro-protective effects of berberine and/or pentoxifylline on the reduction of diclofenac-induced acute kidney injury in rats." | 3.91 | Berberine and Pentoxifylline: A novel combination in amelioration of acute kidney injury. ( Al-Gareeb, AI; Al-Kuraishy, HM; Hussien, NR, 2019) |
| " Since pentoxifylline (PTX) and steroids have distinct immunomodulatory properties, we aimed to evaluate for the first time their combined use in IRI-induced acute kidney injury (AKI) and chronic kidney disease (CKD) in rats." | 3.88 | Pentoxifylline and Methylprednisolone Additively Alleviate Kidney Failure and Prolong Survival of Rats after Renal Warm Ischemia-Reperfusion. ( Grzeszczak, W; Król, R; Więcek, A; Wystrychowski, A; Wystrychowski, G; Wystrychowski, W, 2018) |
| " Pentoxifylline (PTX) given before IRI attenuates inflammation and prevents ischemic acute kidney injury (iAKI)." | 3.80 | Nephroprotective effect of pentoxifylline in renal ischemia-reperfusion in rat depends on the timing of its administration. ( Grzeszczak, W; Obuchowicz, E; Więcek, A; Wystrychowski, A; Wystrychowski, G; Wystrychowski, W; Zukowska-Szczechowska, E, 2014) |
| "The beneficial effects of post-insult administration of pentoxifylline, a novel hemorheologic agent experimentally studied in various ischemic diseases, were evaluated in two models of acute renal failure (ARF): direct nephrotoxicity (mercuric chloride 4 mg/kg via femoral vein) and hemoglobinuria (glycerol 10 ml/kg i." | 3.67 | Effects of pentoxifylline in experimental acute renal failure. ( Brunner, LJ; Luke, DR; Vadiei, K, 1989) |
| "Diclofenac (15 mg/kg) was injected on day-4, -5 and -6 in all groups except normal control group." | 1.62 | Phosphodiesterase (1, 3 & 5) inhibitors attenuate diclofenac-induced acute kidney toxicity in rats. ( Abdel-Razek, NS; Salem, HA; Wadie, W, 2021) |
| "Gentamicin (GM) is a widely used antibiotic against serious and life-threatening infections, but its usefulness is limited by the development of nephrotoxicity." | 1.35 | Protective effects of pentoxifylline treatment on gentamicin-induced nephrotoxicity in rats. ( Mihailovic, D; Radenkovic, M; Randjelovic, P; Rankovic, G; Stoiljkovic, M; Stojiljkovic, N; Veljkovic, S, 2009) |
| "Pentoxifylline has been shown to improve tissue oxygenation and endothelial function and inhibit proinflammatory cytokine production." | 1.35 | Pentoxifylline in ischemia-induced acute kidney injury in rats. ( Martinelli, R; Okumura, AS; Rodrigues, LE, 2009) |
| "Pentoxifylline has several functions including downregulation of TNF-alpha and endothelia-dependent vascular relaxation." | 1.33 | Pentoxifylline protects against endotoxin-induced acute renal failure in mice. ( Basava, V; Falk, S; Reznikov, L; Schrier, R; Wang, W; Zolty, E, 2006) |
| "Pentoxifylline (PTX) has been reported to inhibit TNF-alpha production and prevent several types of acute renal failure." | 1.32 | Beneficial effect of pentoxifylline on cisplatin-induced acute renal failure in rabbits. ( Choi, TR; Jung, JS; Kim, JH; Kim, YK; Kwon, CH; Woo, JS, 2003) |
| "Glycerol treated rats exhibited collecting duct and medullary ascending limb dilation and casts, with focal tubular damage, confined mainly to the superficial cortex." | 1.31 | Nephroprotective effects of pentoxifylline in experimental myoglobinuric acute renal failure. ( Avramovic, V; Djordjevic, V; Mitic-Zlatkovic, M; Savic, V; Stefanovic, V; Vlahovic, P, 2002) |
| "The pathogenesis of acute renal failure may involve, among other causes, ischemia, vascular congestion, arachidonic acid pathways, and reactive oxygen metabolites." | 1.31 | Effect of vitamin E and pentoxifylline on glycerol-induced acute renal failure. ( Akpolat, I; Akpolat, T; Bedir, A; Coşar, AM; Kandemir, B; Oztürk, H; Sarikaya, S, 2000) |
| " A total of 48 rats were orally dosed with CSA 25 mg/kg for 10 days with either PTX 45 mg/kg i." | 1.28 | Prevention of cyclosporine-induced nephrotoxicity with pentoxifylline. ( Brunner, LJ; Iyer, LV; Luke, DR; Vadiei, K, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (9.38) | 18.7374 |
| 1990's | 5 (15.63) | 18.2507 |
| 2000's | 12 (37.50) | 29.6817 |
| 2010's | 9 (28.13) | 24.3611 |
| 2020's | 3 (9.38) | 2.80 |
| Authors | Studies |
|---|---|
| Al-Kharashi, L | 1 |
| Attia, H | 1 |
| Alsaffi, A | 1 |
| Almasri, T | 1 |
| Arafa, M | 1 |
| Hasan, I | 1 |
| Alajami, H | 1 |
| Ali, R | 1 |
| Badr, A | 1 |
| Tyson, LD | 1 |
| Atkinson, S | 1 |
| Hunter, RW | 1 |
| Allison, M | 1 |
| Austin, A | 1 |
| Dear, JW | 1 |
| Forrest, E | 1 |
| Liu, T | 1 |
| Lord, E | 1 |
| Masson, S | 1 |
| Nunes, J | 1 |
| Richardson, P | 1 |
| Ryder, SD | 1 |
| Wright, M | 1 |
| Thursz, M | 1 |
| Vergis, N | 1 |
| Hussien, NR | 1 |
| Al-Kuraishy, HM | 1 |
| Al-Gareeb, AI | 1 |
| Wadie, W | 1 |
| Abdel-Razek, NS | 1 |
| Salem, HA | 1 |
| Wystrychowski, G | 2 |
| Wystrychowski, W | 3 |
| Grzeszczak, W | 2 |
| Więcek, A | 3 |
| Król, R | 1 |
| Wystrychowski, A | 3 |
| Aslanabadi, N | 1 |
| Afsar Gharebagh, R | 1 |
| Moharramzadeh, S | 1 |
| Entezari-Maleki, T | 1 |
| Yavari, V | 1 |
| Ostovan, MA | 1 |
| Kojuri, J | 1 |
| Afshariani, R | 2 |
| Hamidian Jahromi, A | 2 |
| Hamidian, A | 1 |
| Roozbeh, J | 2 |
| Pakfetrat, M | 2 |
| Zukowska-Szczechowska, E | 1 |
| Obuchowicz, E | 2 |
| Sharifian, M | 1 |
| Stojiljkovic, N | 1 |
| Veljkovic, S | 1 |
| Mihailovic, D | 1 |
| Stoiljkovic, M | 1 |
| Radenkovic, M | 1 |
| Rankovic, G | 1 |
| Randjelovic, P | 1 |
| Groesdonk, HV | 1 |
| Bauer, A | 1 |
| Kreft, B | 1 |
| Heringlake, M | 1 |
| Paarmann, H | 1 |
| Pagel, H | 1 |
| Król, P | 1 |
| Cierpka, L | 1 |
| Okumura, AS | 1 |
| Rodrigues, LE | 1 |
| Martinelli, R | 1 |
| Bansal, S | 1 |
| Wang, W | 2 |
| Falk, S | 2 |
| Schrier, R | 2 |
| Barkhordari, K | 1 |
| Karimi, A | 1 |
| Shafiee, A | 1 |
| Soltaninia, H | 1 |
| Khatami, MR | 1 |
| Abbasi, K | 1 |
| Yousefshahi, F | 1 |
| Haghighat, B | 1 |
| Brown, V | 1 |
| Firouzi, A | 1 |
| Eshraghi, A | 1 |
| Shakerian, F | 1 |
| Sanati, HR | 1 |
| Salehi, N | 1 |
| Zahedmehr, A | 1 |
| Kiani, R | 1 |
| Madani, M | 1 |
| Pedarzadeh, A | 1 |
| Seifi, B | 1 |
| Kadkhodaee, M | 1 |
| Delavari, F | 1 |
| Mikaeili, S | 1 |
| Shams, S | 1 |
| Ostad, SN | 1 |
| Nasiri-Toosi, Z | 1 |
| Dashti-Khavidaki, S | 1 |
| Khalili, H | 1 |
| Lessan-Pezeshki, M | 1 |
| Ramesh, G | 1 |
| Reeves, WB | 1 |
| Savic, V | 1 |
| Vlahovic, P | 1 |
| Djordjevic, V | 1 |
| Mitic-Zlatkovic, M | 1 |
| Avramovic, V | 1 |
| Stefanovic, V | 1 |
| Kim, YK | 2 |
| Choi, TR | 1 |
| Kwon, CH | 1 |
| Kim, JH | 1 |
| Woo, JS | 2 |
| Jung, JS | 2 |
| Zolty, E | 1 |
| Basava, V | 1 |
| Reznikov, L | 1 |
| Boldt, J | 1 |
| Müller, M | 1 |
| Heesen, M | 1 |
| Martin, K | 1 |
| Hempelmann, G | 1 |
| Akpolat, T | 1 |
| Akpolat, I | 1 |
| Oztürk, H | 1 |
| Sarikaya, S | 1 |
| Coşar, AM | 1 |
| Bedir, A | 1 |
| Kandemir, B | 1 |
| Yoo, JH | 1 |
| Kim, BS | 1 |
| Kim, SY | 1 |
| Luke, DR | 5 |
| Vadiei, K | 3 |
| Lopez-Berestein, G | 1 |
| Bianco, JA | 1 |
| Appelbaum, FR | 1 |
| Nemunaitis, J | 1 |
| Almgren, J | 1 |
| Andrews, F | 1 |
| Kettner, P | 1 |
| Shields, A | 1 |
| Singer, JW | 1 |
| Berens, KL | 2 |
| Langston, JD | 1 |
| Wasan, KM | 1 |
| Verani, RR | 1 |
| Brunner, LJ | 2 |
| Iyer, LV | 1 |
| Levin, GIa | 1 |
| Tsarevskiĭ, NN | 1 |
| Vazina, IR | 1 |
1 review available for pentoxifylline and Acute Kidney Failure
| Article | Year |
|---|---|
A review of the potential protective effects of pentoxifylline against drug-induced nephrotoxicity.
Topics: Acute Kidney Injury; Animals; Anti-Infective Agents; Contrast Media; Cytotoxins; Humans; Immunosuppr | 2013 |
6 trials available for pentoxifylline and Acute Kidney Failure
| Article | Year |
|---|---|
Pentoxifylline for the prevention of contrast-induced nephropathy in diabetic patients undergoing angioplasty: a randomized controlled trial.
Topics: Acute Kidney Injury; Aged; Angioplasty; Biomarkers; Contrast Media; Creatinine; Cystatin C; Diabetes | 2019 |
The preventive effect of pentoxifylline on contrast-induced nephropathy: a randomized clinical trial.
Topics: Acute Kidney Injury; Adult; Amidohydrolases; Contrast Media; Fluid Therapy; Free Radical Scavengers; | 2014 |
Effect of pentoxifylline on preventing acute kidney injury after cardiac surgery by measuring urinary neutrophil gelatinase - associated lipocalin.
Topics: Acute Kidney Injury; Acute-Phase Proteins; Biomarkers; Coronary Artery Bypass; Coronary Disease; Dos | 2011 |
Efficacy of pentoxifylline in prevention of contrast-induced nephropathy in angioplasty patients.
Topics: Acute Kidney Injury; Adult; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Co | 2012 |
The effects of pentoxifylline on circulating adhesion molecules in critically ill patients with acute renal failure treated by continuous veno-venous hemofiltration.
Topics: Acute Kidney Injury; Cell Adhesion Molecules; Endothelium, Lymphatic; Female; Humans; Infusions, Int | 1996 |
Phase I-II trial of pentoxifylline for the prevention of transplant-related toxicities following bone marrow transplantation.
Topics: Acute Disease; Acute Kidney Injury; Adult; Bone Marrow Transplantation; Drug Administration Schedule | 1991 |
25 other studies available for pentoxifylline and Acute Kidney Failure
| Article | Year |
|---|---|
Pentoxifylline and thiamine ameliorate rhabdomyolysis-induced acute kidney injury in rats via suppressing TLR4/NF-κB and NLRP-3/caspase-1/gasdermin mediated-pyroptosis.
Topics: Acute Kidney Injury; Animals; Antioxidants; Caspase 1; Creatinine; Gasdermins; Glycerol; Male; NF-ka | 2023 |
In severe alcohol-related hepatitis, acute kidney injury is prevalent, associated with mortality independent of liver disease severity, and can be predicted using IL-8 and micro-RNAs.
Topics: Acute Kidney Injury; Biomarkers; Hepatitis, Alcoholic; Humans; Interleukin-8; MicroRNAs; Patient Acu | 2023 |
Berberine and Pentoxifylline: A novel combination in amelioration of acute kidney injury.
Topics: Acute Kidney Injury; Analysis of Variance; Animals; Berberine; Biomarkers; Creatinine; Cystatin C; D | 2019 |
Phosphodiesterase (1, 3 & 5) inhibitors attenuate diclofenac-induced acute kidney toxicity in rats.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Cilostazol; Creatinine; Diclofenac; Kidney; Male; | 2021 |
Pentoxifylline and Methylprednisolone Additively Alleviate Kidney Failure and Prolong Survival of Rats after Renal Warm Ischemia-Reperfusion.
Topics: Acute Kidney Injury; Animals; Glucocorticoids; Kidney; Male; Methylprednisolone; Pentoxifylline; Rat | 2018 |
Nephroprotective effect of pentoxifylline in renal ischemia-reperfusion in rat depends on the timing of its administration.
Topics: Acute Kidney Injury; Animals; Constriction; Free Radical Scavengers; Inflammation; Kidney; Kidney Tr | 2014 |
Protective effect of pentoxifylline on contrast induced nephropathy.
Topics: Acute Kidney Injury; Contrast Media; Humans; Pentoxifylline; Vasodilator Agents | 2008 |
Protective effects of pentoxifylline treatment on gentamicin-induced nephrotoxicity in rats.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Blood Urea Nitrogen; Creatinine; Gentamicins; M | 2009 |
Urodilatin and pentoxifylline prevent the early onset of Escherichia coli-induced acute renal failure in a model of isolated perfused rat kidney.
Topics: Acute Kidney Injury; Animals; Atrial Natriuretic Factor; Disease Models, Animal; Escherichia coli In | 2009 |
Pentoxifylline augments fasting-induced nephroprotection in acute ischemic kidney injury in rats.
Topics: Acute Kidney Injury; Animal Feed; Animals; Creatinine; Fasting; Ischemia; Kidney Tubules; Male; Neph | 2009 |
Pentoxifylline in ischemia-induced acute kidney injury in rats.
Topics: Acute Kidney Injury; Animals; Cell Respiration; Disease Models, Animal; Free Radical Scavengers; Isc | 2009 |
Combination therapy with albumin and pentoxifylline protects against acute kidney injury during endotoxemic shock in mice.
Topics: Acute Kidney Injury; Albumins; Animals; Disease Models, Animal; Drug Therapy, Combination; Male; Mic | 2009 |
Pretreatment with pentoxifylline and N-acetylcysteine in liver ischemia reperfusion-induced renal injury.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Disease Models, Animal; Dose-Response Relationship, Dr | 2012 |
TNF-alpha mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity.
Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Chemokines; Cisplatin; Cytokines; Dipeptides; E | 2002 |
Nephroprotective effects of pentoxifylline in experimental myoglobinuric acute renal failure.
Topics: Acute Kidney Injury; Animals; Glomerular Mesangium; Glycerol; Kidney; Kidney Diseases; Kidney Glomer | 2002 |
Beneficial effect of pentoxifylline on cisplatin-induced acute renal failure in rabbits.
Topics: Acute Kidney Injury; Animals; Apoptosis; Base Sequence; Cisplatin; Disease Models, Animal; Female; G | 2003 |
Pentoxifylline protects against endotoxin-induced acute renal failure in mice.
Topics: Acute Kidney Injury; Alprostadil; Animals; Cyclic AMP; Cyclic GMP; Disease Models, Animal; Down-Regu | 2006 |
Effect of vitamin E and pentoxifylline on glycerol-induced acute renal failure.
Topics: Acute Kidney Injury; Animals; Creatine Kinase; Creatinine; Disease Models, Animal; Glycerol; Kidney | 2000 |
Effect of pentoxifylline on ischemic acute renal failure in rabbits.
Topics: Acute Kidney Injury; Animals; Depression, Chemical; Kidney; Male; Monosaccharide Transport Proteins; | 2001 |
Role of vascular congestion in cisplatin-induced acute renal failure in the rat.
Topics: Acute Kidney Injury; Animals; Cisplatin; Erythrocytes; Female; Glomerular Filtration Rate; Kidney; M | 1992 |
Influence of pentoxifylline and related analogues in endotoxemic renal failure.
Topics: Acute Kidney Injury; Animals; Dose-Response Relationship, Drug; Endotoxins; Escherichia coli; Kidney | 1991 |
Benefit of vascular decongestion in glycerol-induced acute renal failure.
Topics: Acute Kidney Injury; Analysis of Variance; Animals; Blood Vessels; Dose-Response Relationship, Drug; | 1991 |
Prevention of cyclosporine-induced nephrotoxicity with pentoxifylline.
Topics: Acute Kidney Injury; Animals; Biological Availability; Cyclosporins; Disease Models, Animal; Epopros | 1989 |
Effects of pentoxifylline in experimental acute renal failure.
Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Glycerol; Hemogl | 1989 |
[Importance of correcting the microcirculatory disorders in the transfusion therapy of acute kidney failure in experimental burn shock].
Topics: Acute Kidney Injury; Animals; Blood Transfusion; Burns; Combined Modality Therapy; Heparin; Hydroxye | 1987 |