pentoxifylline has been researched along with Acute Disease in 93 studies
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In acute pancreatitis (AP) tumor necrosis factor-α mediates multi-organ failure; in animal models its blockade with pentoxifylline ameliorates AP." | 9.20 | Pentoxifylline Treatment in Severe Acute Pancreatitis: A Pilot, Double-Blind, Placebo-Controlled, Randomized Trial. ( Atwal, T; Bi, Y; Chari, ST; Clemens, MA; Enders, FT; Vege, SS, 2015) |
| "An earlier pilot study from our liver unit suggested benefit from treatment with pentoxifylline (PTX), an inhibitor of tumor necrosis factor (TNF), in severe acute alcoholic hepatitis." | 9.09 | Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: a double-blind, placebo-controlled trial. ( Akriviadis, E; Botla, R; Briggs, W; Han, S; Reynolds, T; Shakil, O, 2000) |
| "The short-term effects of pentoxifylline (PTX) on granulomatous lesions during Schistosoma mansoni infection in Swiss mice were evaluated." | 7.76 | Effects of pentoxifylline during Schistosoma mansoni infection in Swiss mice: an analysis of worm burden, fecundity and liver histopathology. ( Freitas, RM; Mati, VL; Melo, AL, 2010) |
| "To evaluate the efficiency of pentoxifylline (PTX), a methyl xanthine derivative, in preventing renal scar formation after the induction of pyelonephritis in an experimental rat model with delayed antimicrobial therapy." | 7.72 | Preventive effect of pentoxifylline on renal scarring in rat model of pyelonephritis. ( Boleken, ME; Dindar, H; Ertoy, D; Gokcora, IH; Ozsan, M; Yagmurlu, A, 2003) |
| "In patients with an acute destructive pancreatitis the lowering of sulphhydride (SH) groups in proteinic and nonproteinic fraction of the blood plasma, the reduction of the ascorbic acid level and increase of its oxidized forms concentration was noted." | 7.70 | [The function of the thiol-disulfide and ascorbate systems in patients operated on for acute pancreatitis after the use of low-intensity infrared laser radiation and pentoxifylline]. ( Zaporozhchenko, BS, 1998) |
| "Treatment with pentoxifylline failed to improve outcome in a model of severe acute pancreatitis in the rat." | 7.69 | Failure of pentoxifylline to ameliorate severe acute pancreatitis in the rat: results of a prospective, randomized, controlled study. ( Bassi, DG; Fernández-del Castillo, C; Foitzik, T; Lewandrowski, K; Rattner, DW; Warshaw, AL, 1994) |
| "We investigated the effect of pentoxifylline (PTX) on the development of pulmonary edema in a model of adult respiratory distress syndrome in rabbits." | 7.68 | Effect of pentoxifylline on hemodynamics, alveolar fluid reabsorption, and pulmonary edema in a model of acute lung injury. ( Hannam, VL; Kaapa, P; O'Brodovich, HM; Raj, JU; Seear, MD, 1990) |
| "The effects of pentoxifylline on pulmonary hemodynamics were studied in anesthetized dogs during acute alveolar hypoxia." | 7.67 | Effects of pentoxifylline on pulmonary hemodynamics during acute hypoxia in anesthetized dogs. ( Chick, TW; Doyle, MP; Icenogle, MV; Loeppky, JA; Riedel, CE; Scotto, P; Sikes, CW; Wood, SC, 1988) |
| "In patients with sudden hearing loss, no significant differences of hearing recovery were detected between the three treatment groups." | 6.67 | A randomized, double-blind, placebo-controlled study of dextran/pentoxifylline medication in acute acoustic trauma and sudden hearing loss. ( Kellerhals, B; Lüdin, E; Pfaltz, CR; Podvinec, M; Probst, R; Tschopp, K, 1992) |
| " The dosage of Pentoxifylline in controlled release tablet form is one 400 mg tablet three times a day with meals." | 6.41 | Pentoxifylline. Adjunctive therapy in the treatment of pedal frostbite. ( Considine, C; Hayes, DW; Mandracchia, VJ; Webb, GE, 2000) |
| "Pentoxifylline (PTX) has been shown to attenuate neutrophil activation and end-organ injury in shock states such as hemorrhage and sepsis." | 5.35 | Pentoxifylline attenuates pulmonary inflammation and neutrophil activation in experimental acute pancreatitis. ( Coimbra, R; de Campos, T; Deree, J; Loomis, WH; Martins, JO; Putnam, JG; Shenvi, E, 2008) |
| "Pentoxifylline is a phosphodiesterase inhibitor with marked anti-inflammatory properties through blockade of extracellular signal regulated kinase (ERK) phosphorylation and tumor necrosis factor alpha production." | 5.35 | Pentoxifylline prevents loss of PP2A phosphatase activity and recruitment of histone acetyltransferases to proinflammatory genes in acute pancreatitis. ( Aparisi, L; Escobar, J; Franco, L; López-Rodas, G; Pereda, J; Rodriguez, JL; Sabater, L; Sacilotto, N; Sandoval, J; Sastre, J, 2009) |
| "In acute pancreatitis (AP) tumor necrosis factor-α mediates multi-organ failure; in animal models its blockade with pentoxifylline ameliorates AP." | 5.20 | Pentoxifylline Treatment in Severe Acute Pancreatitis: A Pilot, Double-Blind, Placebo-Controlled, Randomized Trial. ( Atwal, T; Bi, Y; Chari, ST; Clemens, MA; Enders, FT; Vege, SS, 2015) |
| "To study the effect of pentoxifylline and octreotide administration on serum levels of TNF-alpha and IL-6, in patients who underwent endoscopic retrograde cholangiopancreatography (ERCP), whether they developed pancreatitis or not." | 5.14 | Randomized study of the effect of pentoxifylline or octreotide on serum levels of TNF-alpha and IL-6 after endoscopic retrograde cholangiopancreatography. ( Chatzizisi, O; Christodoulou, D; Kapetanos, D; Katodritou, E; Kiriazis, G; Kitis, G; Kokozidis, G; Sigounas, D; Stavropoulou, E; Tsianos, E; Vasiliou, K, 2009) |
| "The pentoxifylline application in complex therapy of an acute pancreatitis had promoted the reduction of the antiinflammatory cytokines contents in the blood serum and the disease course relief." | 5.09 | [The use of anti-cytokines in the treatment of acute pancreatitis]. ( Chuklin, SM; Detsyk, IaB; Pereiaslov, AA, 1999) |
| "An earlier pilot study from our liver unit suggested benefit from treatment with pentoxifylline (PTX), an inhibitor of tumor necrosis factor (TNF), in severe acute alcoholic hepatitis." | 5.09 | Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: a double-blind, placebo-controlled trial. ( Akriviadis, E; Botla, R; Briggs, W; Han, S; Reynolds, T; Shakil, O, 2000) |
| " Pentoxifylline is an effective alternative reducing the occurrence of hepatorenal syndrome." | 4.90 | Prognosis and treatment of patients with acute alcoholic hepatitis. ( Burroughs, AK; Papastergiou, V; Tsochatzis, EA, 2014) |
| "We have previously described that pentoxifylline alone, or in combination with oxypurinol, reduces the systemic inflammation caused by experimentally-induced pancreatitis in rats." | 3.96 | Pentoxifylline and Oxypurinol: Potential Drugs to Prevent the ( Franco, L; López-Iranzo, FJ; López-Rodas, AM; López-Rodas, G, 2020) |
| "The short-term effects of pentoxifylline (PTX) on granulomatous lesions during Schistosoma mansoni infection in Swiss mice were evaluated." | 3.76 | Effects of pentoxifylline during Schistosoma mansoni infection in Swiss mice: an analysis of worm burden, fecundity and liver histopathology. ( Freitas, RM; Mati, VL; Melo, AL, 2010) |
| "The aim of the present study was to investigate whether pentoxifylline (PTX) treatment could protect against induced acute radiation enteritis." | 3.76 | Preventive effect of pentoxifylline on acute radiation damage via antioxidant and anti-inflammatory pathways. ( Ademoğlu, E; Akguner, T; Erbil, Y; Hepgül, G; Olgaç, V; Tanrikulu, S; Unalp, HR, 2010) |
| " In the present study, pentoxifylline (PTX), an inhibitor of TNF-alpha was investigated on its action upon splenic necrosis, parasitemia and host survival." | 3.74 | Importance of TNF-alpha in the course of acute infection with Trypanosoma cruzi: influence of its inhibition by pentoxifylline treatment. ( Andrade, SG; Magalhães, Ldos A; Pessina, DH, 2008) |
| "Intravenous therapy with prednisolone, hydroxyethyl starch 3% and pentoxifylline in the acute postoperative period does not improve hearing in patients who develop acute deafness after attempted hearing preservation surgery for AN." | 3.73 | Steroid and vasoactive treatment for acute deafness after attempted hearing preservation acoustic neuroma surgery. ( Gouveris, H; Mann, W; Maurer, J; Mewes, T, 2005) |
| "To evaluate the efficiency of pentoxifylline (PTX), a methyl xanthine derivative, in preventing renal scar formation after the induction of pyelonephritis in an experimental rat model with delayed antimicrobial therapy." | 3.72 | Preventive effect of pentoxifylline on renal scarring in rat model of pyelonephritis. ( Boleken, ME; Dindar, H; Ertoy, D; Gokcora, IH; Ozsan, M; Yagmurlu, A, 2003) |
| "The purposes of this study were to determine the tumor necrosis factor (TNF) and interleukin-6 (IL-6) levels after the induction of acute necrotizing pancreatitis, and to establish the effects of pentoxifylline on cytokine production." | 3.70 | Beneficial effects of pentoxifylline treatment of experimental acute pancreatitis in rats. ( Balogh, A; Farkas, G; Jarmay, K; Lonovics, J; Marton, J; Nagy, Z; Szasz, Z; Takacs, T; Varga, J, 1998) |
| "In patients with an acute destructive pancreatitis the lowering of sulphhydride (SH) groups in proteinic and nonproteinic fraction of the blood plasma, the reduction of the ascorbic acid level and increase of its oxidized forms concentration was noted." | 3.70 | [The function of the thiol-disulfide and ascorbate systems in patients operated on for acute pancreatitis after the use of low-intensity infrared laser radiation and pentoxifylline]. ( Zaporozhchenko, BS, 1998) |
| "Treatment with pentoxifylline failed to improve outcome in a model of severe acute pancreatitis in the rat." | 3.69 | Failure of pentoxifylline to ameliorate severe acute pancreatitis in the rat: results of a prospective, randomized, controlled study. ( Bassi, DG; Fernández-del Castillo, C; Foitzik, T; Lewandrowski, K; Rattner, DW; Warshaw, AL, 1994) |
| "We investigated the effect of pentoxifylline (PTX) on the development of pulmonary edema in a model of adult respiratory distress syndrome in rabbits." | 3.68 | Effect of pentoxifylline on hemodynamics, alveolar fluid reabsorption, and pulmonary edema in a model of acute lung injury. ( Hannam, VL; Kaapa, P; O'Brodovich, HM; Raj, JU; Seear, MD, 1990) |
| "The effects of pentoxifylline on pulmonary hemodynamics were studied in anesthetized dogs during acute alveolar hypoxia." | 3.67 | Effects of pentoxifylline on pulmonary hemodynamics during acute hypoxia in anesthetized dogs. ( Chick, TW; Doyle, MP; Icenogle, MV; Loeppky, JA; Riedel, CE; Scotto, P; Sikes, CW; Wood, SC, 1988) |
| "Idiopathic sudden sensorineural hearing loss (ISSNHL) is defined as a 30-decibel (dB) loss in hearing over three contiguous frequencies within 3 days." | 2.87 | Does the addition of hyperbaric oxygen therapy to conventional treatment modalities influence the outcome of soldiers with idiopathic sudden sensorineural hearing loss? ( Chen, RF; Chi, TH; Chiang, MC; Yuan, CH, 2018) |
| "Pentoxifylline was administered intravenously in a dose of 600 mg daily for 5 days, together with oral aspirin 150 mg daily." | 2.67 | Pentoxifylline in the treatment of acute ischaemic stroke--a reappraisal in Chinese stroke patients. ( Chan, YW; Kay, CS, 1993) |
| "In patients with sudden hearing loss, no significant differences of hearing recovery were detected between the three treatment groups." | 2.67 | A randomized, double-blind, placebo-controlled study of dextran/pentoxifylline medication in acute acoustic trauma and sudden hearing loss. ( Kellerhals, B; Lüdin, E; Pfaltz, CR; Podvinec, M; Probst, R; Tschopp, K, 1992) |
| "Prednisolone has become the principal agent for treating patients with severe AH." | 2.53 | Acute Alcoholic Hepatitis: Therapy. ( Lucey, MR; Phillips, PK, 2016) |
| "Radiation enteritis is a severe problem in patients receiving irradiation of the abdomen or pelvis in the course of cancer treatment." | 2.44 | Medical prevention and treatment of acute and chronic radiation induced enteritis--is there any proven therapy? a short review. ( Böcker, U; Singer, MV; Wenz, F; Zimmerer, T, 2008) |
| "Classification of tinnitus is oriented to the duration of symptoms and their severity, the latter taking into account the victim's distress both at work and during leisure time." | 2.42 | [Tinnitus--classification, causes, diagnosis, treatment and prognosis]. ( Koester, M; Storck, C; Zorowka, P, 2004) |
| " The dosage of Pentoxifylline in controlled release tablet form is one 400 mg tablet three times a day with meals." | 2.41 | Pentoxifylline. Adjunctive therapy in the treatment of pedal frostbite. ( Considine, C; Hayes, DW; Mandracchia, VJ; Webb, GE, 2000) |
| "Pentoxifylline (PTX) has been shown to attenuate neutrophil activation and end-organ injury in shock states such as hemorrhage and sepsis." | 1.35 | Pentoxifylline attenuates pulmonary inflammation and neutrophil activation in experimental acute pancreatitis. ( Coimbra, R; de Campos, T; Deree, J; Loomis, WH; Martins, JO; Putnam, JG; Shenvi, E, 2008) |
| "The prognosis of acute pancreatitis (AP) depends upon the degree of pancreatic necrosis and the intensity of multisystem organ failure." | 1.35 | Comparative effects of several therapatic agents on hepatic damage induced by acute experimental pancreatitis. ( Eşrefoğlu, M; Gül, M; Turan, F, 2008) |
| "Pentoxifylline is a phosphodiesterase inhibitor with marked anti-inflammatory properties through blockade of extracellular signal regulated kinase (ERK) phosphorylation and tumor necrosis factor alpha production." | 1.35 | Pentoxifylline prevents loss of PP2A phosphatase activity and recruitment of histone acetyltransferases to proinflammatory genes in acute pancreatitis. ( Aparisi, L; Escobar, J; Franco, L; López-Rodas, G; Pereda, J; Rodriguez, JL; Sabater, L; Sacilotto, N; Sandoval, J; Sastre, J, 2009) |
| "During experimental studies on the treatment of acute pancreatitis, we observed that when pentoxifylline was administered after anaesthesia with thiopental, most of the rats exhibited dyspnea, signs of pulmonary oedema and died." | 1.33 | Co-administration of pentoxifylline and thiopental causes death by acute pulmonary oedema in rats. ( Alberola, A; Cerdá, M; Escobar, J; Fabregat, G; García-de-la-Asunción, J; García-de-la-Asuneión, J; Gómez-Cambronero, L; Pereda, J; Sabater, L; Sastre, J; Viña, J, 2006) |
| "38 g/m2/day, which is comparable to the maximum tolerated dosage in humans." | 1.29 | Effect of high-dose pentoxifylline on acute radiation-induced lung toxicity in a rat lung perfusion model. ( Griffin, TW; Koh, WJ; Peterson, LM; Stelzer, KJ, 1996) |
| "coli septicemia plus PTXF bolus 20 mg/kg injected 5 min before E." | 1.27 | Attenuation of acute lung injury in septic guinea pigs by pentoxifylline. ( Harada, H; Hogue, RS; Ishizaka, A; O'Hanley, PT; Raffin, TA; Stephens, KE; Wu, ZH, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (24.73) | 18.7374 |
| 1990's | 32 (34.41) | 18.2507 |
| 2000's | 26 (27.96) | 29.6817 |
| 2010's | 11 (11.83) | 24.3611 |
| 2020's | 1 (1.08) | 2.80 |
| Authors | Studies |
|---|---|
| López-Iranzo, FJ | 1 |
| López-Rodas, AM | 1 |
| Franco, L | 2 |
| López-Rodas, G | 2 |
| Chi, TH | 1 |
| Chiang, MC | 1 |
| Chen, RF | 1 |
| Yuan, CH | 1 |
| Gallo, L | 1 |
| Sarnacchiaro, P | 1 |
| Papastergiou, V | 1 |
| Burroughs, AK | 1 |
| Tsochatzis, EA | 1 |
| Chanson, P | 1 |
| Pariente, A | 1 |
| Vege, SS | 1 |
| Atwal, T | 1 |
| Bi, Y | 1 |
| Chari, ST | 1 |
| Clemens, MA | 1 |
| Enders, FT | 1 |
| Liao, CY | 1 |
| Huang, SC | 1 |
| Lin, CH | 1 |
| Wang, CC | 1 |
| Liu, MY | 1 |
| Ben, RJ | 1 |
| Kuo, WH | 1 |
| Lee, CC | 1 |
| Phillips, PK | 1 |
| Lucey, MR | 1 |
| de Campos, T | 1 |
| Deree, J | 1 |
| Martins, JO | 1 |
| Loomis, WH | 1 |
| Shenvi, E | 1 |
| Putnam, JG | 1 |
| Coimbra, R | 1 |
| Khaira, A | 1 |
| Gupta, V | 1 |
| Gupta, A | 1 |
| Mahajan, S | 1 |
| Bhowmik, D | 1 |
| Tiwari, SC | 1 |
| Fraser, SG | 1 |
| Adams, W | 1 |
| Hepgül, G | 1 |
| Tanrikulu, S | 1 |
| Unalp, HR | 1 |
| Akguner, T | 1 |
| Erbil, Y | 1 |
| Olgaç, V | 1 |
| Ademoğlu, E | 1 |
| Kapetanos, D | 1 |
| Christodoulou, D | 1 |
| Chatzizisi, O | 1 |
| Sigounas, D | 1 |
| Vasiliou, K | 1 |
| Stavropoulou, E | 1 |
| Katodritou, E | 1 |
| Kokozidis, G | 1 |
| Kiriazis, G | 1 |
| Kitis, G | 1 |
| Tsianos, E | 1 |
| Sandoval, J | 1 |
| Escobar, J | 2 |
| Pereda, J | 3 |
| Sacilotto, N | 1 |
| Rodriguez, JL | 1 |
| Sabater, L | 3 |
| Aparisi, L | 1 |
| Sastre, J | 3 |
| Batcioglu, K | 1 |
| Gul, M | 2 |
| Uyumlu, AB | 1 |
| Esrefoglu, M | 2 |
| Chooklin, S | 1 |
| Pereyaslov, A | 1 |
| Bihalskyy, I | 1 |
| Nowak, Ł | 1 |
| Zurowski, D | 1 |
| Garlicki, J | 1 |
| Thor, PJ | 1 |
| Oliveira-Júnior, IS | 2 |
| Oliveira, IS | 1 |
| Oliveira, WR | 1 |
| Cavassani, SS | 1 |
| Brunialti, MK | 2 |
| Salomao, R | 2 |
| Mati, VL | 1 |
| Freitas, RM | 1 |
| Melo, AL | 1 |
| Kim, H | 1 |
| Kim, Y | 1 |
| Guk, K | 1 |
| Yoo, D | 1 |
| Lim, H | 1 |
| Kang, G | 1 |
| Lee, D | 1 |
| Stelzer, KJ | 1 |
| Koh, WJ | 1 |
| Peterson, LM | 1 |
| Griffin, TW | 1 |
| Yagmurlu, A | 1 |
| Boleken, ME | 1 |
| Ertoy, D | 1 |
| Ozsan, M | 1 |
| Gokcora, IH | 1 |
| Dindar, H | 1 |
| Linke, R | 1 |
| Mazurek, B | 1 |
| Matschke, RG | 1 |
| Granell, S | 1 |
| Gómez-Cambronero, L | 2 |
| Cassinello, N | 1 |
| Closa, D | 1 |
| Parés, A | 1 |
| Caballería, J | 1 |
| Gouveris, H | 2 |
| Mewes, T | 1 |
| Maurer, J | 1 |
| Mann, W | 2 |
| Stenner, M | 1 |
| Jecker, P | 1 |
| Alberola, A | 1 |
| Fabregat, G | 1 |
| Cerdá, M | 1 |
| García-de-la-Asunción, J | 1 |
| García-de-la-Asuneión, J | 1 |
| Viña, J | 1 |
| Mota, MR | 1 |
| Criddle, DN | 1 |
| Alencar, NM | 1 |
| Gomes, RC | 1 |
| Meireles, AV | 1 |
| Santi-Gadelha, T | 1 |
| Gadelha, CA | 1 |
| Oliveira, CC | 1 |
| Benevides, RG | 1 |
| Cavada, BS | 1 |
| Assreuy, AM | 1 |
| Koh, IH | 1 |
| Junqueira, VB | 1 |
| Turan, F | 1 |
| Andrade, SG | 1 |
| Magalhães, Ldos A | 1 |
| Pessina, DH | 1 |
| Koester, M | 1 |
| Storck, C | 1 |
| Zorowka, P | 1 |
| Zimmerer, T | 1 |
| Böcker, U | 1 |
| Wenz, F | 1 |
| Singer, MV | 1 |
| Il'in, VN | 1 |
| Stepanov, NV | 1 |
| Ikhaev, ZA | 1 |
| Sharonin, GV | 1 |
| Bogdanets, LI | 1 |
| Sergeeva, NA | 1 |
| Terekhova, TV | 1 |
| Koshkin, VM | 3 |
| Adil'khanov, SG | 3 |
| Sapozhnikov, VA | 1 |
| Beyreder, J | 2 |
| Shtok, VN | 1 |
| Fedorova, NV | 1 |
| Gadanova, IV | 1 |
| Muggeo, M | 1 |
| Calabrò, A | 1 |
| Businaro, V | 1 |
| Patussi, L | 1 |
| Volpe, A | 1 |
| Signorini, GP | 1 |
| Crepaldi, G | 1 |
| Shevkhuzhev, ZA | 1 |
| Khanamatov, MKh | 1 |
| Shen, CY | 1 |
| Hsu, K | 1 |
| Wang, D | 1 |
| Yan, HC | 1 |
| Chan, YW | 1 |
| Kay, CS | 1 |
| Bassi, DG | 1 |
| Foitzik, T | 1 |
| Rattner, DW | 1 |
| Lewandrowski, K | 1 |
| Warshaw, AL | 1 |
| Fernández-del Castillo, C | 1 |
| Skjeldal, S | 1 |
| Hvaal, K | 1 |
| Nordsletten, L | 1 |
| Aasen, AO | 1 |
| Reikerås, O | 1 |
| Torvik, A | 1 |
| Gara, II | 1 |
| Hervé, P | 1 |
| Pizarro, A | 1 |
| Navarro, A | 1 |
| Sáez-Royuela, F | 1 |
| López-Vázquez, A | 1 |
| López-Morante, A | 1 |
| Díez-Sánchez, V | 1 |
| Martín-Lorente, JL | 1 |
| Staak, K | 1 |
| Prosch, S | 1 |
| Stein, J | 1 |
| Priemer, C | 1 |
| Ewert, R | 1 |
| Docke, WD | 1 |
| Kruger, DH | 1 |
| Volk, HD | 1 |
| Reinke, P | 1 |
| Biesinger, E | 1 |
| Heiden, C | 1 |
| Greimel, V | 1 |
| Lendle, T | 1 |
| Höing, R | 1 |
| Albegger, K | 1 |
| Marton, J | 1 |
| Farkas, G | 1 |
| Takacs, T | 1 |
| Nagy, Z | 1 |
| Szasz, Z | 1 |
| Varga, J | 1 |
| Jarmay, K | 1 |
| Balogh, A | 1 |
| Lonovics, J | 1 |
| Zaporozhchenko, BS | 2 |
| Fomochkin, II | 3 |
| Kolbasin, PN | 2 |
| Zaporozhchenko, VS | 1 |
| Estey, EH | 1 |
| Thall, PF | 1 |
| Reed, P | 1 |
| Kantarjian, H | 1 |
| Beran, M | 1 |
| Pierce, S | 1 |
| Keating, MJ | 1 |
| Kazakova, VV | 1 |
| Gangneux, JP | 1 |
| Chau, F | 1 |
| Sulahian, A | 1 |
| Derouin, F | 1 |
| Garin, YJ | 1 |
| Metternich, FU | 1 |
| Brusis, T | 1 |
| Pereiaslov, AA | 1 |
| Chuklin, SM | 1 |
| Detsyk, IaB | 1 |
| Hayes, DW | 1 |
| Mandracchia, VJ | 1 |
| Considine, C | 1 |
| Webb, GE | 1 |
| Akriviadis, E | 1 |
| Botla, R | 1 |
| Briggs, W | 1 |
| Han, S | 1 |
| Reynolds, T | 1 |
| Shakil, O | 1 |
| Sittel, C | 1 |
| Stennert, E | 1 |
| Markou, K | 1 |
| Lalaki, P | 1 |
| Barbetakis, N | 1 |
| Tsalighopoulos, MG | 1 |
| Daniilidis, I | 1 |
| Karnam, US | 1 |
| Schulz, CE | 1 |
| Richter, W | 1 |
| Naujoks, J | 1 |
| Küchle, HJ | 1 |
| Zatevakhin, II | 1 |
| Shestakov, VA | 1 |
| Il'in, SG | 1 |
| Antonova, NIu | 1 |
| Probst, R | 1 |
| Tschopp, K | 1 |
| Lüdin, E | 1 |
| Kellerhals, B | 1 |
| Podvinec, M | 1 |
| Pfaltz, CR | 1 |
| Truog, WE | 1 |
| Gibson, RL | 1 |
| Henderson, WR | 1 |
| Redding, GJ | 1 |
| Standaert, TA | 1 |
| Clift, R | 1 |
| Buckner, CD | 1 |
| Bianco, J | 1 |
| Petersen, F | 1 |
| Appelbaum, F | 1 |
| Hartmann, A | 2 |
| Rommel, T | 1 |
| Dettmers, C | 1 |
| Tsuda, Y | 1 |
| Lagrèze, H | 1 |
| Broich, K | 1 |
| Gal'perin, EI | 1 |
| Tatishvili, GG | 1 |
| Akhaladze, GG | 1 |
| Sakevarashvili, GR | 1 |
| Nasirov, FN | 1 |
| Aref'ev, AE | 1 |
| Bianco, JA | 1 |
| Appelbaum, FR | 1 |
| Nemunaitis, J | 1 |
| Almgren, J | 1 |
| Andrews, F | 1 |
| Kettner, P | 1 |
| Shields, A | 1 |
| Singer, JW | 1 |
| Seear, MD | 1 |
| Hannam, VL | 1 |
| Kaapa, P | 1 |
| Raj, JU | 1 |
| O'Brodovich, HM | 1 |
| Ott, E | 1 |
| Chandra, B | 1 |
| Lupal'tsev, VI | 1 |
| Desloovere, C | 1 |
| Lörz, M | 1 |
| Klima, A | 1 |
| Okyayuz-Baklouti, I | 1 |
| Ishizaka, A | 3 |
| Hatherill, JR | 2 |
| Harada, H | 2 |
| Yonemaru, M | 2 |
| Hoffmann, H | 2 |
| Zheng, H | 2 |
| O'Hanley, PT | 2 |
| Raffin, TA | 3 |
| Teuscher, T | 1 |
| Von Der Ahe, CW | 1 |
| Baillod, P | 1 |
| Holzer, B | 1 |
| Fujishima, S | 1 |
| Tesi, M | 1 |
| Bronchi, GF | 1 |
| Carini, A | 1 |
| Karavassili, M | 1 |
| Wu, ZH | 1 |
| Stephens, KE | 1 |
| Hogue, RS | 1 |
| Chick, TW | 1 |
| Scotto, P | 1 |
| Icenogle, MV | 1 |
| Sikes, CW | 1 |
| Doyle, MP | 1 |
| Riedel, CE | 1 |
| Wood, SC | 1 |
| Loeppky, JA | 1 |
| Hsu, CY | 1 |
| Norris, JW | 1 |
| Hogan, EL | 1 |
| Bladin, P | 1 |
| Dinsdale, HB | 1 |
| Yatsu, FM | 1 |
| Earnest, MP | 1 |
| Scheinberg, P | 1 |
| Caplan, LR | 1 |
| Karp, HR | 1 |
| Ivanov, IV | 1 |
| Barkagan, LZ | 1 |
| Zorzon, M | 1 |
| Monti, F | 1 |
| Del Pio Luogo, T | 1 |
| Cazzato, G | 1 |
| Garnier, R | 1 |
| Riboulet-Delmas, G | 1 |
| Chatenet, T | 1 |
| Efthymiou, ML | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pentoxifylline Treatment in Acute Pancreatitis; A Double-Blind Placebo-Controlled Randomized Trial[NCT01292005] | Early Phase 1 | 28 participants (Actual) | Interventional | 2009-04-30 | Completed | ||
| A Phase II Study to Establish the Efficacy of Synthetic Human SecretiN in Human Acute Pancreatitis (SNAP) Study[NCT03686618] | Phase 2 | 40 participants (Anticipated) | Interventional | 2018-10-01 | Recruiting | ||
| Effect of Omega-5 Fatty Acid Supplement on Markers of Inflammation and Oxidative Stress in Patients With Severe Alcoholic Hepatitis Treated With Prednisone[NCT03732586] | 40 participants (Actual) | Interventional | 2018-09-30 | Completed | |||
| Comparison of Bovine Colostrum Versus Placebo in Treatment of Severe Alcoholic Hepatitis: A Randomized Double Blind Controlled Trial[NCT02473341] | Phase 3 | 174 participants (Actual) | Interventional | 2017-11-14 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT01292005)
Timeframe: 30 days or until dismissal date, whichever occurs earlier
| Intervention | days (Median) |
|---|---|
| Pentoxifylline | 3 |
| Placebo | 5 |
(NCT01292005)
Timeframe: 30 days or until dismissal date, whichever occurs earlier
| Intervention | Days (Median) |
|---|---|
| Pentoxifylline | 0 |
| Placebo | 0 |
(NCT01292005)
Timeframe: 30 days, or until dismissal, whichever came first
| Intervention | participants (Number) |
|---|---|
| Pentoxifylline | 0 |
| Placebo | 4 |
(NCT01292005)
Timeframe: 1 week or until dismissal date whichever occurs earlier.
| Intervention | participants (Number) |
|---|---|
| Pentoxifylline | 0 |
| Placebo | 3 |
(NCT01292005)
Timeframe: 1 week or until dismissal date whichever occurs earlier
| Intervention | participants (Number) |
|---|---|
| Pentoxifylline | 0 |
| Placebo | 2 |
C-reactive protein is produced by the liver. The level of CRP rises when there is inflammation throughout the body. The normal value range for CRP = 1-10 mg/L. (NCT01292005)
Timeframe: baseline, Day 1, Day 3
| Intervention | mg/L (Median) | |
|---|---|---|
| Change from baseline to Day 1 | Change from baseline to Day 3 | |
| Pentoxifylline | 48.4 | 62 |
| Placebo | 60.6 | 154 |
Normal value range for IL-6 = 0 - 5 pg/ml. (NCT01292005)
Timeframe: baseline, Day 1, Day 3
| Intervention | pg/ml (Median) | |
|---|---|---|
| Change from baseline to Day 1 | Change from baseline to Day 2 | |
| Pentoxifylline | 2.1 | -8.6 |
| Placebo | 0.7 | -2.9 |
Normal value range for TNF alpha = 0 - 22 pg/ml. (NCT01292005)
Timeframe: baseline, Day 1, Day 3
| Intervention | pg/ml (Median) | |
|---|---|---|
| Change from baseline to Day 1 | Change from baseline to Day 3 | |
| Pentoxifylline | 0 | 0.2 |
| Placebo | -0.05 | -0.3 |
Normal value range for IL-8 = 0 - 5 pg/ml. (NCT01292005)
Timeframe: baseline, Day 1, Day 3
| Intervention | pg/ml (Median) | |
|---|---|---|
| Change from baseline to Day 1 | Change from baseline to Day 3 | |
| Pentoxifylline | -3.0 | 0.35 |
| Placebo | -1.7 | -1.9 |
"Lengthy was defined as either greater than 4 days or greater than 10 days." (NCT01292005)
Timeframe: 30 days or until dismissal date, whichever occurs earlier
| Intervention | participants (Number) | |
|---|---|---|
| Length of hospitalization >4 days | Length of hospitalization >10 days | |
| Pentoxifylline | 2 | 0 |
| Placebo | 8 | 5 |
9 reviews available for pentoxifylline and Acute Disease
| Article | Year |
|---|---|
Prognosis and treatment of patients with acute alcoholic hepatitis.
Topics: Acetylcysteine; Acute Disease; Adrenal Cortex Hormones; Antioxidants; Drug Resistance; Drug Therapy, | 2014 |
Acute Alcoholic Hepatitis: Therapy.
Topics: Acute Disease; Alcohol Abstinence; Antioxidants; Glucocorticoids; Hepatitis, Alcoholic; Humans; Live | 2016 |
Interventions for acute non-arteritic central retinal artery occlusion.
Topics: Acute Disease; Counterpulsation; Hemodilution; Humans; Pentoxifylline; Randomized Controlled Trials | 2009 |
[Physiopathological bases for the treatment of acute alcoholic hepatitis].
Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Alcoholism; Anabolic Agents; Antibodies, Monoclonal; | 2004 |
[Tinnitus--classification, causes, diagnosis, treatment and prognosis].
Topics: Acute Disease; Adaptation, Physiological; Administration, Oral; Anti-Inflammatory Agents; Audiometry | 2004 |
Medical prevention and treatment of acute and chronic radiation induced enteritis--is there any proven therapy? a short review.
Topics: Abdominal Neoplasms; Acute Disease; Chronic Disease; Combined Modality Therapy; Controlled Clinical | 2008 |
[Strategies in ambulatory treatment of tinnitus].
Topics: Acute Disease; Ambulatory Care; Combined Modality Therapy; Diagnosis, Differential; Hearing Loss, Su | 1998 |
[Clinical effectiveness of trental and thiotriazolinum in the treatment of acute pancreatitis].
Topics: Acute Disease; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Pancreatitis; Pentoxifylline; T | 1999 |
Pentoxifylline. Adjunctive therapy in the treatment of pedal frostbite.
Topics: Acute Disease; Animals; Combined Modality Therapy; Foot; Frostbite; Hematologic Agents; Humans; Pent | 2000 |
17 trials available for pentoxifylline and Acute Disease
| Article | Year |
|---|---|
Does the addition of hyperbaric oxygen therapy to conventional treatment modalities influence the outcome of soldiers with idiopathic sudden sensorineural hearing loss?
Topics: Acute Disease; Adolescent; Adult; Aged; Combined Modality Therapy; Dextrans; Drug Therapy, Combinati | 2018 |
Pentoxifylline Treatment in Severe Acute Pancreatitis: A Pilot, Double-Blind, Placebo-Controlled, Randomized Trial.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Humans; Interleukin-6; I | 2015 |
Pentoxifylline Treatment in Severe Acute Pancreatitis: A Pilot, Double-Blind, Placebo-Controlled, Randomized Trial.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Humans; Interleukin-6; I | 2015 |
Pentoxifylline Treatment in Severe Acute Pancreatitis: A Pilot, Double-Blind, Placebo-Controlled, Randomized Trial.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Humans; Interleukin-6; I | 2015 |
Pentoxifylline Treatment in Severe Acute Pancreatitis: A Pilot, Double-Blind, Placebo-Controlled, Randomized Trial.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Humans; Interleukin-6; I | 2015 |
Randomized study of the effect of pentoxifylline or octreotide on serum levels of TNF-alpha and IL-6 after endoscopic retrograde cholangiopancreatography.
Topics: Acute Disease; Adult; Aged; Biomarkers; Cholangiopancreatography, Endoscopic Retrograde; Female; Gas | 2009 |
Use of pentoxifylline in the treatment of acute cerebrovascular insufficiency.
Topics: Acute Disease; Benzamides; Cerebrovascular Disorders; Clinical Trials as Topic; Drug Therapy, Combin | 1983 |
[Therapy of acute cerebrovascular insufficiency].
Topics: Acute Disease; Arrhythmias, Cardiac; Brain Ischemia; Cerebral Infarction; Double-Blind Method; Femal | 1981 |
Pentoxifylline in the treatment of acute ischaemic stroke--a reappraisal in Chinese stroke patients.
Topics: Acute Disease; Aged; Asian People; Brain Ischemia; Cerebrovascular Disorders; China; Double-Blind Me | 1993 |
Treatment of newly diagnosed AML, RAEB-t or RAEB with lisofylline or placebo in addition to chemotherapy.
Topics: Acute Disease; Aged; Anemia, Refractory, with Excess of Blasts; Anti-Infective Agents; Antineoplasti | 1999 |
[The use of anti-cytokines in the treatment of acute pancreatitis].
Topics: Acute Disease; Antibodies; Blood-Brain Barrier; Cytokines; Enzyme Inhibitors; Humans; Pancreatitis; | 1999 |
Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: a double-blind, placebo-controlled trial.
Topics: Acute Disease; Adult; Cohort Studies; Disease Progression; Double-Blind Method; Female; Hepatitis, A | 2000 |
The efficacy of medication on tinnitus due to acute acoustic trauma.
Topics: Acute Disease; Adolescent; Adult; Auditory Threshold; Follow-Up Studies; Hearing Loss, Noise-Induced | 2001 |
A toast to pentoxifylline.
Topics: Acute Disease; Double-Blind Method; Hepatitis, Alcoholic; Humans; Pentoxifylline; Phosphodiesterase | 2001 |
[On the treatment of acute arterial circulatory disturbances of the retina and optic nerve (author's transl)].
Topics: Acute Disease; Aged; Anticoagulants; Arterial Occlusive Diseases; Bencyclane; Clinical Trials as Top | 1977 |
A randomized, double-blind, placebo-controlled study of dextran/pentoxifylline medication in acute acoustic trauma and sudden hearing loss.
Topics: Acoustic Stimulation; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Audiometry, Pure-To | 1992 |
Phase I-II trial of pentoxifylline for the prevention of transplant-related toxicities following bone marrow transplantation.
Topics: Acute Disease; Acute Kidney Injury; Adult; Bone Marrow Transplantation; Drug Administration Schedule | 1991 |
Double-blind randomised clinical trial of pentoxiphyllin in vaso-occlusive sickle cell crisis.
Topics: Acute Disease; Adolescent; Analgesics; Anemia, Sickle Cell; Child; Double-Blind Method; Female; Huma | 1989 |
Therapy of atherosclerotic arteriopathy of lower limbs. Aspects and results.
Topics: Acute Disease; Arteriosclerosis; Chronic Disease; Clinical Trials as Topic; Glycosaminoglycans; Hepa | 1985 |
Pentoxifylline in acute nonhemorrhagic stroke. A randomized, placebo-controlled double-blind trial.
Topics: Acute Disease; Adult; Cerebrovascular Disorders; Clinical Trials as Topic; Double-Blind Method; Huma | 1988 |
67 other studies available for pentoxifylline and Acute Disease
| Article | Year |
|---|---|
Pentoxifylline and Oxypurinol: Potential Drugs to Prevent the
Topics: Acute Disease; Animals; Betacoronavirus; Coronavirus Infections; COVID-19; Cytokine Release Syndrome | 2020 |
Ten-year experience with multimodal treatment for acute phase Peyronie's disease: A real life clinical report.
Topics: Acute Disease; Administration, Oral; Arginine; Clinical Protocols; Combined Modality Therapy; Drug A | 2019 |
[Pentoxifylline against prednisolone in severe acute alcoholic hepatitis: a Korean trial].
Topics: Acute Disease; Adult; Hepatitis, Alcoholic; Humans; Multicenter Studies as Topic; Pentoxifylline; Pr | 2014 |
Successful resolution of symmetrical peripheral gangrene after severe acute pancreatitis: a case report.
Topics: Acute Disease; Adult; Fingers; Gangrene; Humans; Male; Pancreatitis; Pentoxifylline; Platelet Aggreg | 2015 |
Pentoxifylline attenuates pulmonary inflammation and neutrophil activation in experimental acute pancreatitis.
Topics: Acute Disease; Amylases; Animals; Anti-Inflammatory Agents; Chemokine CXCL1; Disease Models, Animal; | 2008 |
Rare presentation of a common disease of tropics.
Topics: Acute Disease; Adult; Amebicides; Anti-Bacterial Agents; Antimalarials; Artemisinins; Artesunate; Ce | 2008 |
Preventive effect of pentoxifylline on acute radiation damage via antioxidant and anti-inflammatory pathways.
Topics: Acute Disease; Animals; Dinoprostone; Enteritis; Glutathione; Ileum; Immunohistochemistry; Intercell | 2010 |
Pentoxifylline prevents loss of PP2A phosphatase activity and recruitment of histone acetyltransferases to proinflammatory genes in acute pancreatitis.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Blotting, Western; Cell Line; Chromatin Immunoprec | 2009 |
Liver lipid peroxidation and antioxidant capacity in cerulein-induced acute pancreatitis.
Topics: Acute Disease; Animals; Arginine; Ceruletide; Female; Free Radical Scavengers; Lipid Peroxidation; L | 2009 |
Pathogenic role of myeloperoxidase in acute pancreatitis.
Topics: Acute Disease; Anti-Inflammatory Agents; Biomarkers; Case-Control Studies; Cytokines; Enzyme-Linked | 2009 |
[Role of pendoxifiline (PTX) in different and cute and chronic models of pain in rats].
Topics: Acute Disease; Animals; Chronic Disease; Cytokines; Dose-Response Relationship, Drug; Inflammation; | 2008 |
Effects of pentoxifylline on inflammation and lung dysfunction in ventilated septic animals.
Topics: Acute Disease; Analysis of Variance; Animals; Bronchoalveolar Lavage; Disease Models, Animal; Enzyme | 2010 |
Effects of pentoxifylline during Schistosoma mansoni infection in Swiss mice: an analysis of worm burden, fecundity and liver histopathology.
Topics: Acute Disease; Animals; Chronic Disease; Female; Fertility; Granuloma; Liver; Male; Mice; Parasite E | 2010 |
Fully biodegradable and cationic poly(amino oxalate) particles for the treatment of acetaminophen-induced acute liver failure.
Topics: Acetaminophen; Acute Disease; Animals; Cell Line; Chemical and Drug Induced Liver Injury; Cytosol; D | 2012 |
Effect of high-dose pentoxifylline on acute radiation-induced lung toxicity in a rat lung perfusion model.
Topics: Acute Disease; Animals; Lung; Male; Pentoxifylline; Pilot Projects; Radiation Injuries, Experimental | 1996 |
Preventive effect of pentoxifylline on renal scarring in rat model of pyelonephritis.
Topics: Acute Disease; Animals; Cicatrix; Disease Models, Animal; Escherichia coli; Escherichia coli Infecti | 2003 |
[Subjective assessment of acute tinnitus and proposal of a tinnitus score].
Topics: Acute Disease; Adult; Audiometry; Audiometry, Evoked Response; Data Interpretation, Statistical; Fem | 2003 |
Circulating TNF-alpha and its soluble receptors during experimental acute pancreatitis.
Topics: Acute Disease; Animals; Disease Models, Animal; Male; Pancreatitis; Pentoxifylline; Rats; Rats, Wist | 2004 |
Steroid and vasoactive treatment for acute deafness after attempted hearing preservation acoustic neuroma surgery.
Topics: Acute Disease; Anti-Inflammatory Agents; Deafness; Drug Therapy, Combination; Evoked Potentials, Aud | 2005 |
[Treatment of sensorineural hearing loss in acute viral otitis media with intratympanic dexamethasone and hyaluronic acid in comparison with intravenous therapy].
Topics: Acute Disease; Adjuvants, Immunologic; Adult; Anti-Inflammatory Agents; Audiometry; Bone Conduction; | 2006 |
Co-administration of pentoxifylline and thiopental causes death by acute pulmonary oedema in rats.
Topics: Acute Disease; Anesthetics, Intravenous; Animals; Drug Interactions; Injections, Intraperitoneal; Ma | 2006 |
Modulation of acute inflammation by a chitin-binding lectin from Araucaria angustifolia seeds via mast cells.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Capillary Permeability; Chitin; Dose-Response Rela | 2006 |
Effect of pentoxifylline on lung inflammation and gas exchange in a sepsis-induced acute lung injury model.
Topics: Acute Disease; Animals; Disease Models, Animal; Escherichia coli Infections; Inflammation; Inflammat | 2006 |
Comparative effects of several therapatic agents on hepatic damage induced by acute experimental pancreatitis.
Topics: Acetylcysteine; Acute Disease; Animals; Antioxidants; Arginine; Ascorbic Acid; Ceruletide; Female; L | 2008 |
Importance of TNF-alpha in the course of acute infection with Trypanosoma cruzi: influence of its inhibition by pentoxifylline treatment.
Topics: Acute Disease; Animals; Chagas Disease; Immunohistochemistry; Mice; Mice, Inbred C3H; Necrosis; Para | 2008 |
[Postoperative antithrombotic therapy in acute occlusion of the major arteries of the extremities].
Topics: Acute Disease; Adolescent; Adult; Aged; Arm; Arterial Occlusive Diseases; Aspirin; Dextrans; Female; | 1980 |
[Some mechanisms of papaverine and trental action in patients with acute arterial obstruction].
Topics: Acute Disease; Adrenocorticotropic Hormone; Aged; Arm; Cyclic AMP; Embolism; Hemodynamics; Humans; H | 1980 |
[Clinical study of the cerebrovascular action of pentoxifylline].
Topics: Acute Disease; Adult; Arteriosclerosis; Brain Ischemia; Cerebrovascular Disorders; Chronic Disease; | 1982 |
[Hemocoagulation, fibrinolytic and rheologic parameters in ischemic vasculopathy. Effects of pentoxifylline in the treatment of acute cerebral vasculopathy].
Topics: Acute Disease; Blood Coagulation; Brain Ischemia; Drug Evaluation; Female; Fibrinogen; Fibrinolysis; | 1981 |
[Endolymphatic drug infusion in the treatment of complicated acute appendicitis].
Topics: Abscess; Acute Disease; Anti-Bacterial Agents; Appendicitis; Aprotinin; Aspirin; Cefotaxime; Ceftazi | 1993 |
Pentoxifylline attenuates acute lung injury induced by microemboli.
Topics: Acute Disease; Animals; Blood Platelets; Blood Pressure; Bronchoalveolar Lavage Fluid; Calcium Chlor | 1995 |
Failure of pentoxifylline to ameliorate severe acute pancreatitis in the rat: results of a prospective, randomized, controlled study.
Topics: Acute Disease; Analysis of Variance; Animals; Ceruletide; Chi-Square Distribution; Disease Models, A | 1994 |
Pentoxifylline reduces skeletal muscle necrosis after acute hindlimb ischemia in rats.
Topics: Acute Disease; Animals; Hindlimb; Ischemia; Male; Muscles; Necrosis; Pentoxifylline; Rats; Rats, Wis | 1994 |
[The effect of pentoxifylline and nicergoline on the systemic and cerebral hemodynamics and on the blood rheological properties in patients with an ischemic stroke and atherosclerotic lesions of the major cerebral arteries].
Topics: Acute Disease; Adult; Aged; Blood Flow Velocity; Blood Viscosity; Brain Ischemia; Cerebrovascular Di | 1993 |
Prevention and treatment of acute GvHD--new modalities.
Topics: Acute Disease; Antibodies, Monoclonal; Bone Marrow Transplantation; Combined Modality Therapy; Graft | 1993 |
[The treatment of a case of recurrent oral aphthosis with pentoxifylline].
Topics: Acute Disease; Aged; Female; Humans; Pentoxifylline; Recurrence; Stomatitis, Aphthous | 1993 |
Pentoxifylline-induced acute hepatitis.
Topics: Acute Disease; Aged; Aged, 80 and over; Chemical and Drug Induced Liver Injury; Female; Humans; Pent | 1995 |
Cell Therapeutics Inc. reports novel therapy for acute respiratory distress syndrome--the largest cause of mortality in patients with multiple traumatic injuries.
Topics: Acute Disease; Adjuvants, Immunologic; Antineoplastic Agents; Bone Marrow Transplantation; Clinical | 1996 |
Pentoxifylline promotes replication of human cytomegalovirus in vivo and in vitro.
Topics: Acute Disease; Antigens, Viral; Cells, Cultured; Chloramphenicol O-Acetyltransferase; Cytomegaloviru | 1997 |
Beneficial effects of pentoxifylline treatment of experimental acute pancreatitis in rats.
Topics: Acute Disease; Animals; Body Weight; Interleukin-6; Male; Organ Size; Pancreatitis, Acute Necrotizin | 1998 |
[The function of the thiol-disulfide and ascorbate systems in patients operated on for acute pancreatitis after the use of low-intensity infrared laser radiation and pentoxifylline].
Topics: Acute Disease; Adult; Ascorbic Acid; Combined Modality Therapy; Disulfides; Female; Humans; Infrared | 1998 |
[The effect of trental and thiotriazoline on tissue blood flow, oxygen tension and vascular reactivity in the pancreas in acute experimental pancreatitis].
Topics: Acute Disease; Animals; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Hemodynamics; Ox | 1998 |
[Changes in blood enzyme activity and tumor necrosis factor level in the treatment of experimental pancreatitis with pentoxifylline].
Topics: Acute Disease; alpha-Amylases; Animals; Enzyme-Linked Immunosorbent Assay; Male; Pancreatitis; Pento | 1998 |
[Effects of trental and thiotriazoline on neutrophil dehydrogenase activity in acute experimental pancreatitis].
Topics: Acute Disease; Animals; Dogs; Neutrophils; Oxidoreductases; Pancreatitis; Pentoxifylline; Triazoles; | 1998 |
[Changes in immunity status after surgery on acute pancreatitis with the use of pentoxifylline and low intensity infrared laser irradiation].
Topics: Acute Disease; Adult; Female; Humans; Immunoglobulins; Infrared Rays; Laser Therapy; Male; Middle Ag | 1998 |
Effects of immunosuppressive therapy on murine Leishmania infantum visceral leishmaniosis.
Topics: Acute Disease; Animals; Dexamethasone; Female; Hydrocortisone; Immunophenotyping; Immunosuppressive | 1999 |
[Acute hearing loss and tinnitus caused by amplified recreational music].
Topics: Acute Disease; Adolescent; Adult; Audiometry, Pure-Tone; Dose-Response Relationship, Drug; Drug Ther | 1999 |
Prognostic value of electromyography in acute peripheral facial nerve palsy.
Topics: Acute Disease; Anti-Inflammatory Agents; Anticoagulants; Dextrans; Electromyography; Facial Muscles; | 2001 |
[Viscosity of blood and sensorineural hearing loss (author's transl)].
Topics: Acute Disease; Audiometry; Blood Viscosity; Capillaries; Chronic Disease; Erythrocytes; Hearing Diso | 1977 |
[Effect of papaverine and trental on hemostasis and rheologic properties of blood in acute arterial obstruction].
Topics: Acute Disease; Blood Viscosity; Hemostasis; Humans; Papaverine; Pentoxifylline; Theobromine; Thrombo | 1979 |
[Peripheral macro-and microcirculatory changes in acute arterial obstruction with papaverine and trental administration].
Topics: Acute Disease; Arterial Occlusive Diseases; Blood Circulation; Drug Evaluation; Embolism; Hemodynami | 1979 |
Effect of pentoxifylline on cytokine- and eicosanoid-induced acute pulmonary hypertension in piglets.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acute Disease; Animals; Animals, | 1992 |
Marrow transplantation in patients with acute myeloid leukemia.
Topics: Acute Disease; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Drug Administration Schedule | 1992 |
Hemodilution in cerebral infarcts.
Topics: Acute Disease; Animals; Cerebral Infarction; Cerebrovascular Circulation; Dextrans; Glucose; Hemodil | 1991 |
[Disorders of organic hemodynamics of the liver and their correction in suppurative cholangitis].
Topics: Acute Disease; Animals; Aprotinin; Ascorbic Acid; Aspirin; Cholangitis; Cholestasis; Dextrans; Dipyr | 1991 |
Effect of pentoxifylline on hemodynamics, alveolar fluid reabsorption, and pulmonary edema in a model of acute lung injury.
Topics: Absorption; Acute Disease; Animals; Capillary Permeability; Extravascular Lung Water; Hemodynamics; | 1990 |
Pentoxifylline alters the natural course of acute nonhemorrhagic stroke.
Topics: Acute Disease; Cerebrovascular Disorders; Humans; Nervous System; Pentoxifylline; Theobromine | 1990 |
[Use of a combination of rheopolyglucin, complamin and trental in the complex treatment of acute postoperative pancreatitis].
Topics: Acute Disease; Dextrans; Drug Therapy, Combination; Humans; Pancreatitis; Pentoxifylline; Platelet A | 1988 |
Sudden sensorineural hearing loss influence of hemodynamical and hemorheological factors on spontaneous recovery and therapy results.
Topics: Acute Disease; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Ear, Middle; Hearing | 1989 |
The effects of torbafylline on blood flow, pO2 and function of rat ischaemic skeletal muscle.
Topics: Acute Disease; Animals; Blood Pressure; Erythrocytes; Hindlimb; Ischemia; Lactates; Male; Microspher | 1989 |
Prevention of interleukin 2-induced acute lung injury in guinea pigs by pentoxifylline.
Topics: Acute Disease; Animals; Guinea Pigs; Interleukin-2; Lung; Lung Injury; Pentoxifylline; Theobromine | 1989 |
Attenuation of acute lung injury in septic guinea-pigs by a new xanthine derivative (HWA-138).
Topics: Acute Disease; Animals; Blood Pressure; Bronchodilator Agents; Erythrocytes; Escherichia coli Infect | 1989 |
Attenuation of acute lung injury in septic guinea pigs by pentoxifylline.
Topics: Acute Disease; Animals; Bronchoalveolar Lavage Fluid; Escherichia coli Infections; Female; Glucuroni | 1988 |
Effects of pentoxifylline on pulmonary hemodynamics during acute hypoxia in anesthetized dogs.
Topics: Acute Disease; Animals; Blood Pressure; Blood Viscosity; Cardiac Output; Dogs; Erythrocyte Deformabi | 1988 |
[Disorders of thrombocytic hemostasis and their correction with trental in severe forms of acute intestinal infections in children under 1 year of age].
Topics: Acute Disease; Blood Platelet Disorders; Enterobacteriaceae Infections; Enterocolitis; Humans; Infan | 1987 |
[Ticlopidine and pentoxifylline in acute cerebral infarct. Clinical study on 151 patients].
Topics: Acute Disease; Aged; Cerebral Infarction; Drug Therapy, Combination; Female; Follow-Up Studies; Huma | 1987 |
[Acute pentoxifylline poisoning in children].
Topics: Acute Disease; Child, Preschool; Humans; Infant; Male; Pentoxifylline; Theobromine | 1986 |