pentostatin and Kidney-Neoplasms

pentostatin has been researched along with Kidney-Neoplasms* in 3 studies

Trials

1 trial(s) available for pentostatin and Kidney-Neoplasms

Article	Year
Phase II study of 2'-deoxycoformycin in patients with renal cell carcinoma. A National Cancer Institute of Canada Clinical Trials Group study. Investigational new drugs, 1991, Volume: 9, Issue:3 The National Cancer Institute of Canada Clinical Trials Group undertook a phase II study of 2'-deoxycoformycin in patients with metastatic renal cell carcinoma. When 2'-deoxycoformycin 4 mg/m2 was administered intravenously weekly for three weeks then every two weeks no significant antitumor activity was noted in 19 evaluable patients. Toxic effects experienced were as expected, consisting primarily of nausea/vomiting, anorexia, and lethargy. It is concluded that 2'-deoxycoformycin at this dose and schedule has no clinical activity in the treatment of metastatic renal cell carcinoma. Topics: Adult; Aged; Carcinoma, Renal Cell; Dose-Response Relationship, Drug; Drug Evaluation; Female; Humans; Kidney Neoplasms; Male; Middle Aged; Pentostatin	1991

Article

Year

Phase II study of 2'-deoxycoformycin in patients with renal cell carcinoma. A National Cancer Institute of Canada Clinical Trials Group study.

Investigational new drugs, 1991, Volume: 9, Issue:3

The National Cancer Institute of Canada Clinical Trials Group undertook a phase II study of 2'-deoxycoformycin in patients with metastatic renal cell carcinoma. When 2'-deoxycoformycin 4 mg/m2 was administered intravenously weekly for three weeks then every two weeks no significant antitumor activity was noted in 19 evaluable patients. Toxic effects experienced were as expected, consisting primarily of nausea/vomiting, anorexia, and lethargy. It is concluded that 2'-deoxycoformycin at this dose and schedule has no clinical activity in the treatment of metastatic renal cell carcinoma.

Topics: Adult; Aged; Carcinoma, Renal Cell; Dose-Response Relationship, Drug; Drug Evaluation; Female; Humans; Kidney Neoplasms; Male; Middle Aged; Pentostatin

1991

Other Studies

2 other study(ies) available for pentostatin and Kidney-Neoplasms

Article	Year
Pentostatin effective as preparative regimen for kidney transplants. Expert review of anticancer therapy, 2001, Volume: 1, Issue:4 Topics: Humans; Immunosuppressive Agents; Immunotherapy, Adoptive; Kidney Neoplasms; Kidney Transplantation; Pentostatin; Transplantation, Homologous	2001
Evaluation of deoxycoformycin in patients with advanced renal cell carcinoma. An ECOG pilot study. Investigational new drugs, 1992, Volume: 10, Issue:1 Topics: Adult; Aged; Carcinoma, Renal Cell; Female; Humans; Kidney Neoplasms; Male; Middle Aged; Pentostatin; Pilot Projects	1992