pentostatin and Dermatitis--Exfoliative

pentostatin has been researched along with Dermatitis--Exfoliative* in 2 studies

Other Studies

2 other study(ies) available for pentostatin and Dermatitis--Exfoliative

Article	Year
Fatal erythroderma associated with pentostatin. BMJ (Clinical research ed.), 1999, Aug-28, Volume: 319, Issue:7209 Topics: Antibiotics, Antineoplastic; Dermatitis, Exfoliative; Fatal Outcome; Female; Humans; Leukemia, Prolymphocytic; Middle Aged; Pentostatin	1999
[Successful combination chemotherapy including deoxycoformycin in a case of cutaneous T cell lymphoma]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 1996, Volume: 37, Issue:1 A 44-year-old woman was admitted to our department because of fever and skin eruptions on August, 1991. Physical examination revealed superficial lymph node swelling, hepatosplenomegaly and generalized erythroderma. Laboratory findings were as follows; WBC 21,490/microliters with 67% lymphocytes including flower cells. The surface phenotype of lymphocytes was positive for CD2, CD4, CD25, CD29 suggesting helper-inducer T cell. Skin and lymph node biopsies revealed the infiltration of T cells with indented nuclei. Anti-HTLV-1 antibodies in the serum and HTLV-1 proviral DNA analysis by PCR method were negative. She was diagnosed as CTCL, and she was treated with prednisolone. However, her erythroderma deteriorated gradually, in spite of well-controlled lymphocyte counts. Combination chemotherapy, utilizing vincristine, etoposide and cyclophosphamide, was effective against organomegaly but not against generalized erythroderma. After DCF was initiated at a weekly dose of 7.5 mg, her erythroderma improved rapidly and markedly with the disappearance of severe itching, and she achieved complete remission. Our results suggest that DCF is beneficial for chemotherapy-resistant generalized erythroderma in CTCL. Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dermatitis, Exfoliative; Etoposide; Female; Humans; Lymphoma, T-Cell, Cutaneous; Pentostatin; Vincristine	1996

Article

Year

Fatal erythroderma associated with pentostatin.

BMJ (Clinical research ed.), 1999, Aug-28, Volume: 319, Issue:7209

Topics: Antibiotics, Antineoplastic; Dermatitis, Exfoliative; Fatal Outcome; Female; Humans; Leukemia, Prolymphocytic; Middle Aged; Pentostatin

1999

[Successful combination chemotherapy including deoxycoformycin in a case of cutaneous T cell lymphoma].

[Rinsho ketsueki] The Japanese journal of clinical hematology, 1996, Volume: 37, Issue:1

A 44-year-old woman was admitted to our department because of fever and skin eruptions on August, 1991. Physical examination revealed superficial lymph node swelling, hepatosplenomegaly and generalized erythroderma. Laboratory findings were as follows; WBC 21,490/microliters with 67% lymphocytes including flower cells. The surface phenotype of lymphocytes was positive for CD2, CD4, CD25, CD29 suggesting helper-inducer T cell. Skin and lymph node biopsies revealed the infiltration of T cells with indented nuclei. Anti-HTLV-1 antibodies in the serum and HTLV-1 proviral DNA analysis by PCR method were negative. She was diagnosed as CTCL, and she was treated with prednisolone. However, her erythroderma deteriorated gradually, in spite of well-controlled lymphocyte counts. Combination chemotherapy, utilizing vincristine, etoposide and cyclophosphamide, was effective against organomegaly but not against generalized erythroderma. After DCF was initiated at a weekly dose of 7.5 mg, her erythroderma improved rapidly and markedly with the disappearance of severe itching, and she achieved complete remission. Our results suggest that DCF is beneficial for chemotherapy-resistant generalized erythroderma in CTCL.

Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dermatitis, Exfoliative; Etoposide; Female; Humans; Lymphoma, T-Cell, Cutaneous; Pentostatin; Vincristine

1996