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pentobarbital and Tachyarrhythmia

pentobarbital has been researched along with Tachyarrhythmia in 19 studies

Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.

Research Excerpts

ExcerptRelevanceReference
"Intravenous diltiazem (10-300 micrograms/kg), verapamil (10-300 micrograms/kg), nifedipine (1-100 micrograms/kg) and nicardipine (1-100 micrograms/kg) inhibited the tachycardia caused by cardiac sympathetic nerve stimulation (SNS, 0."7.68Inhibitory effects of diltiazem, verapamil, nifedipine, and nicardipine on sympathetic tachycardia in decentralized hearts of anesthetized dogs. ( Kimura, T; Mukaiyama, O; Satoh, E; Satoh, S, 1990)
"Intravenous diltiazem (10-300 micrograms/kg), verapamil (10-300 micrograms/kg), nifedipine (1-100 micrograms/kg) and nicardipine (1-100 micrograms/kg) inhibited the tachycardia caused by cardiac sympathetic nerve stimulation (SNS, 0."3.68Inhibitory effects of diltiazem, verapamil, nifedipine, and nicardipine on sympathetic tachycardia in decentralized hearts of anesthetized dogs. ( Kimura, T; Mukaiyama, O; Satoh, E; Satoh, S, 1990)
" In intact anesthetized, vagotomized rats or in pithed rats with a submaximal tachycardia evoked by electrical stimulation of the spinal cord, clonidine and oxymetazoline, in contrast to cirazoline (5."3.66Functional and biochemical evidence for the lack of cardiac presynaptic alpha-2 adrenoceptor stimulant properties of cirazoline (LD 3098), a potent alpha-1 adrenoceptor agonist in dogs and rats. ( Cavero, I; Gomeni, R; Lefèvre-Borg, F; Roach, AG; Scatton, B, 1982)
"In pentobarbital-treated rats, the sensitivity of the cardiovascular system to nicotine was decreased; in these rats, consecutive nicotine doses did show tachyphylaxis for the pressor and tachycardiac responses."1.29Cardiovascular effects of different schedules of nicotine administration on spinal rats: influence of pentobarbital. ( Cruz, SL; Fernández-Guasti, A; Villarreal, JE, 1994)
"We evaluated the hypothesis that the area postrema facilitates the cardiac arrhythmias caused by toxic doses of digitalis."1.27Lack of protection against ouabain cardiotoxicity after chronic ablation of the area postrema in cats. ( Borison, HL; Riancho, JA; Thron, CD, 1984)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199015 (78.95)18.7374
1990's3 (15.79)18.2507
2000's1 (5.26)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
MITHOEFER, JC1
KAZEMI, H1
MELVILLE, KI1
GILLIS, RA1
SEKELJ, P1
Cavero, I1
Lefèvre-Borg, F1
Roach, AG1
Gomeni, R1
Scatton, B1
Thron, CD1
Riancho, JA1
Borison, HL1
Block, AJ1
Cruz, SL1
Fernández-Guasti, A1
Villarreal, JE1
McDaid, J1
Docherty, JR1
Herman, EH1
Balazs, T1
Young, R1
Earl, FL1
Krop, S1
Ferrans, VJ1
Manders, WT1
Vatner, SF1
Satoh, E1
Mukaiyama, O1
Kimura, T2
Satoh, S1
Bedran-de-Castro, MT1
Farah, VM1
Krieger, EM1
Mayer, DB1
Miletich, DJ1
Feld, JM1
Albrecht, RF1
Hunt, GB1
Ross, DL1
Nishie, K1
Gumbmann, MR1
Keyl, AC1
Hashimoto, K1
Kubota, K1
Levy, MN1
Blattberg, B1
Louhimo, I1
Evers, W1
Racz, GB1
Dobkin, AB1
Rushmer, RF1
Watson, N1
Harding, D1
Baker, D1

Other Studies

19 other studies available for pentobarbital and Tachyarrhythmia

ArticleYear
EFFECT OF CARBON DIOXIDE ON HEART RATE.
    Journal of applied physiology, 1964, Volume: 19

    Topics: Acidosis; Alkalosis; Animals; Atropine; Blood Gas Analysis; Bradycardia; Carbon Dioxide; Chloralose;

1964
CORONARY FLOW, BLOOD PRESSURE, AND HEART RATE DOSE-RESPONSE CHANGES AFTER NITROGLYCERIN ADMINISTRATION.
    Canadian journal of physiology and pharmacology, 1965, Volume: 43

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Coronary Vessels; Dogs; Electrocardiography; Femoral A

1965
Functional and biochemical evidence for the lack of cardiac presynaptic alpha-2 adrenoceptor stimulant properties of cirazoline (LD 3098), a potent alpha-1 adrenoceptor agonist in dogs and rats.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 223, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Blood Vessels; Brimonidine Tartrate; Clonidine;

1982
Lack of protection against ouabain cardiotoxicity after chronic ablation of the area postrema in cats.
    Experimental neurology, 1984, Volume: 85, Issue:3

    Topics: Animals; Cats; Dose-Response Relationship, Drug; Heart; Medulla Oblongata; Ouabain; Pentobarbital; T

1984
Prevention of chloroform-induced ventricular tachycardia in mice as an index of antiarrhythmic activity.
    Life sciences, 1981, Jun-08, Volume: 28, Issue:23

    Topics: Animals; Anti-Arrhythmia Agents; Biological Assay; Chloroform; Electrocardiography; Female; Mice; Pe

1981
Cardiovascular effects of different schedules of nicotine administration on spinal rats: influence of pentobarbital.
    European journal of pharmacology, 1994, Jun-02, Volume: 258, Issue:1-2

    Topics: Animals; Blood Pressure; Bradycardia; Decerebrate State; Dose-Response Relationship, Drug; Drug Admi

1994
Vascular actions of MDMA involve alpha1 and alpha2-adrenoceptors in the anaesthetized rat.
    British journal of pharmacology, 2001, Volume: 133, Issue:3

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Re

2001
Acute cardiomyopathy induced by the vasodilating antihypertensive agent minoxidil.
    Toxicology and applied pharmacology, 1979, Mar-15, Volume: 47, Issue:3

    Topics: Anesthesia; Animals; Arteritis; Cardiomyopathies; Coronary Vessels; Dogs; Hemorrhage; Hypotension; M

1979
Effects of sodium pentobarbital anesthesia on left ventricular function and distribution of cardiac output in dogs, with particular reference to the mechanism for tachycardia.
    Circulation research, 1976, Volume: 39, Issue:4

    Topics: Anesthesia, General; Animals; Atropine; Blood Pressure; Cardiac Output; Coronary Circulation; Denerv

1976
Inhibitory effects of diltiazem, verapamil, nifedipine, and nicardipine on sympathetic tachycardia in decentralized hearts of anesthetized dogs.
    Journal of cardiovascular pharmacology, 1990, Volume: 16, Issue:4

    Topics: Analysis of Variance; Animals; Blood Pressure; Coronary Circulation; Diltiazem; Dogs; Dose-Response

1990
Influence of general anesthetics on baroreflex control of circulation.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1990, Volume: 23, Issue:11

    Topics: Animals; Bradycardia; Chloralose; Heart Rate; Male; Nitroprusside; Pentobarbital; Phenylephrine; Pre

1990
The effects of magnesium salts on the duration of epinephrine-induced ventricular tachyarrhythmias in anesthetized rats.
    Anesthesiology, 1989, Volume: 71, Issue:6

    Topics: Animals; Calcium Chloride; Epinephrine; Halothane; Magnesium Chloride; Magnesium Sulfate; Male; Pent

1989
Comparison of effects of three anesthetic agents on induction of ventricular tachycardia in a canine model of myocardial infarction.
    Circulation, 1988, Volume: 78, Issue:1

    Topics: Animals; Dogs; Droperidol; Drug Combinations; Electric Stimulation; Electrophysiology; Fentanyl; Hal

1988
Pharmacology of solanine.
    Toxicology and applied pharmacology, 1971, Volume: 19, Issue:1

    Topics: Abdomen; Abnormalities, Drug-Induced; Animals; Anophthalmos; Cardiac Complexes, Premature; Central N

1971
Study of the therapeutic and toxic effects of ouabain by simultaneous observations on the excised and blood-perfused sinoatrial node and papillary muscle preparations and the in situ heart of dogs.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 186, Issue:3

    Topics: Adrenal Glands; Adrenalectomy; Anesthesia; Animals; Dogs; Electrocardiography; Heart; Heart Rate; Le

1973
Changes in heart rate induced by bacterial endotoxin.
    The American journal of physiology, 1967, Volume: 213, Issue:6

    Topics: Animals; Blood Pressure; Bradycardia; Chloralose; Dogs; Electrocardiography; Endotoxins; Escherichia

1967
Heart injury after blunt thoracic trauma: an experimental study on rabbits.
    Acta chirurgica Scandinavica. Supplementum, 1968, Volume: 380

    Topics: Animals; Aorta; Aortic Rupture; Blood Pressure Determination; Body Weight; Bradycardia; Bundle-Branc

1968
A study of plasma potassium and electrocardiographic changes after a single dose of succinylcholine.
    Canadian Anaesthetists' Society journal, 1969, Volume: 16, Issue:4

    Topics: Atropine; Bradycardia; Cardiovascular Diseases; Debridement; Diabetes Complications; Electrocardiogr

1969
Compensation to exsanguination hypotension in health conscious dogs.
    The American journal of physiology, 1963, Volume: 205, Issue:5

    Topics: Animals; Aorta; Blood Pressure; Cardiac Output; Dogs; Heart Rate; Heart Ventricles; Hypotension; Pen

1963