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pentobarbital and Suffocation

pentobarbital has been researched along with Suffocation in 27 studies

Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.

Research Excerpts

ExcerptRelevanceReference
" We tested the hypothesis that asphyxia alone can cause cardiorespiratory failure ("failure") in pentobarbital-anesthetized rats."3.80Hypoxia, not hypercapnia, induces cardiorespiratory failure in rats. ( Iscoe, S; Simpson, JA, 2014)
" This unit offers protocols for euthanasia employing carbon dioxide asphyxiation (see Basic Protocol 1), pentobarbital overdose (see Basic Protocol 2), exsanguination, and cervical dislocation for the mouse, rat, hamster, and rabbit."3.73Euthanasia. ( Brown, P; Donovan, J, 2005)
"The antihypoxic effect of the newly-synthesized hydroxylamine barbiturate HB-7, compared with the effects of phenobarbital and pentobarbital, was studied in experiments on albino mice, using the following models of hypoxia: hypobaric, anoxic, asphyctic and haemic."3.67Antihypoxic effect of the hydroxylamine derivative HB-7. ( Georgiev, V; Getova, D, 1989)
"The effects of asphyxia and potassium on the electrocardiogram (ECG), lead II, were recorded from dogs and cats anesthetized with sodium pentobarbital and halothane."3.65Effects of asphyxia and potassium on canine and feline electrocardiograms. ( Coulter, DB; Duncan, RJ; Sander, PD, 1975)
"Asphyxial cardiopulmonary arrest was induced and, after and 8 min cardiac arrest nonintervention interval, a standardized protocol of manual CPR with mechanical ventilation was performed."1.30Anesthetic regimen effects on a pediatric porcine model of asphyxial arrest. ( Ginn, A; Jasani, MS; Nadkarni, VM; Salzman, SK; Tice, LL, 1997)
"Asphyxic anoxia and hypoventilation hypoxia were used as models of general depression."1.27Effect of piracetam in some models of general and local depression of the cortical bioelectrical activity in cats. ( Dimov, S; Moyanova, S; Nikolov, R; Nikolova, M, 1983)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199023 (85.19)18.7374
1990's1 (3.70)18.2507
2000's2 (7.41)29.6817
2010's1 (3.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Simpson, JA1
Iscoe, S1
SNYDER, FF1
VECSEI WEISZ, P1
KEMENY, V1
SHIMAMURA, M2
MORI, S2
MATSUSHIMA, S1
FUJIMORI, B1
PLACHTA, A1
Martindale, D1
Donovan, J1
Brown, P1
Yamauchi, T1
Dimov, S1
Nikolov, R1
Nikolova, M1
Moyanova, S1
Jasani, MS1
Salzman, SK1
Tice, LL1
Ginn, A1
Nadkarni, VM1
Yasuda, H1
Shuto, S1
Tsumagari, T1
Nakajima, A1
Passatore, M1
Myers, RE1
Coulter, DB1
Duncan, RJ1
Sander, PD1
Slavícek, J1
Getova, D1
Georgiev, V1
Dvorák, J1
Trojan, S1
St'astný, F1
Sawyer, CH1
Kawakami, M1
Meyerson, B1
Whitmoyer, DI1
Lilley, JJ1
Rudomin, P1
Dutton, H1
Aoki, VS1
Brody, MJ1
Al-Azzawi, HT1
Stoward, PJ1
Brann, AW1
Montalvo, JM1
Bucher, K1
Huber, B1
Baettig, P1
Aoki, M1
García Ramos, J1
Birzis, L1
Carregal, EJ1
Comline, RS1
Silver, M1

Reviews

2 reviews available for pentobarbital and Suffocation

ArticleYear
ASYPHYXIA RELATIVELY INHERENT TO TRANQUILIZATION. REVIEW OF THE LITERATURE AND REPORT OF SEVEN CASES.
    Archives of general psychiatry, 1965, Volume: 12

    Topics: Asphyxia; Barbiturates; Central Nervous System; Chlorpromazine; Esophagogastric Junction; Hypnotics

1965
Barbiturates and asphyxia.
    Pediatric clinics of North America, 1970, Volume: 17, Issue:4

    Topics: Animals; Animals, Newborn; Asphyxia; Barbiturates; Brain; Carbon Dioxide; Central Nervous System; Fe

1970

Other Studies

25 other studies available for pentobarbital and Suffocation

ArticleYear
Hypoxia, not hypercapnia, induces cardiorespiratory failure in rats.
    Respiratory physiology & neurobiology, 2014, Jun-01, Volume: 196

    Topics: Anesthesia; Animals; Arterial Pressure; Asphyxia; Diaphragm; Heart Failure; Heart Rate; Heart Ventri

2014
The effect of pentobarbital sodium upon the resistance to asphyxia in the newborn.
    Federation proceedings, 1946, Volume: 5, Issue:1 Pt 2

    Topics: Asphyxia; Barbital; Biochemical Phenomena; Humans; Pentobarbital

1946
INVESTIGATIONS CONCERNING THE ALDOSTERONOTROPIC EFFECT OF ACTH.
    Acta physiologica Academiae Scientiarum Hungaricae, 1963, Volume: 24

    Topics: Adrenocorticotropic Hormone; Aldosterone; Asphyxia; Corticosterone; Formaldehyde; Pentobarbital; Phy

1963
ON THE SPINO-BULBO-SPINAL REFLEX IN DOGS, MONKEYS AND MAN.
    The Japanese journal of physiology, 1964, Aug-15, Volume: 14

    Topics: Animals; Asphyxia; Chloralose; Decerebrate State; Dogs; Electric Stimulation; Electromyography; Elec

1964
A culture of death.
    Scientific American, 2005, Volume: 292, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Asphyxia; Confidentiality; Euthanasia; Humans; Pentobarbital; Re

2005
Euthanasia.
    Current protocols in neuroscience, 2005, Volume: Appendix 4

    Topics: Animals; Animals, Laboratory; Asphyxia; Carbon Dioxide; Cricetinae; Euthanasia, Animal; Laboratory A

2005
Interactions of spino-bulbo-spinal reflexes with cortically evoked pyramidal and extrapyramidal activities.
    Brain research, 1967, Volume: 4, Issue:1

    Topics: Animals; Asphyxia; Brain Stem; Cats; Cerebral Cortex; Electric Stimulation; Electrophysiology; Evoke

1967
Effect of piracetam in some models of general and local depression of the cortical bioelectrical activity in cats.
    Archives internationales de pharmacodynamie et de therapie, 1983, Volume: 262, Issue:1

    Topics: Adenosine Monophosphate; Animals; Asphyxia; Cats; Cerebral Cortex; Depression, Chemical; Female; Hyp

1983
Anesthetic regimen effects on a pediatric porcine model of asphyxial arrest.
    Resuscitation, 1997, Volume: 35, Issue:1

    Topics: Adjuvants, Anesthesia; Anesthesia, General; Anesthetics, Combined; Anesthetics, Dissociative; Anesth

1997
Protective effect of a novel imidazole derivative against cerebral anoxia.
    Archives internationales de pharmacodynamie et de therapie, 1978, Volume: 233, Issue:1

    Topics: Animals; Asphyxia; Atmospheric Pressure; Cyanides; Electroencephalography; Female; Hypoxia, Brain; I

1978
Physiological characterization of efferent cervical sympathetic fibers influenced by changes of illumination.
    Experimental neurology, 1976, Volume: 53, Issue:1

    Topics: Animals; Asphyxia; Blood Pressure; Body Temperature; Cats; Cervical Plexus; Evoked Potentials; Light

1976
Maternal psychological stress and fetal asphyxia: a study in the monkey.
    American journal of obstetrics and gynecology, 1975, May-01, Volume: 122, Issue:1

    Topics: Acid-Base Equilibrium; Animals; Animals, Newborn; Asphyxia; Asphyxia Neonatorum; Blood Pressure; Bra

1975
Effects of asphyxia and potassium on canine and feline electrocardiograms.
    Canadian journal of comparative medicine : Revue canadienne de medecine comparee, 1975, Volume: 39, Issue:4

    Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Animals; Arrhythmias, Cardiac; Asphyxia; Blood Pres

1975
[Effect of asphyxia on respiration and heart rate in the rat under ether anaesthesia, under pentobarbital anaesthesia and after adrenalectomy (ontogenetic aspect) (author's transl)].
    Sbornik lekarsky, 1976, Volume: 78, Issue:3

    Topics: Adrenalectomy; Age Factors; Anesthesia, General; Animals; Asphyxia; Ether; Growth; Heart Rate; Pento

1976
Antihypoxic effect of the hydroxylamine derivative HB-7.
    Acta physiologica et pharmacologica Bulgarica, 1989, Volume: 15, Issue:1

    Topics: Animals; Anticonvulsants; Asphyxia; Atmospheric Pressure; Hydroxylamines; Hypoxia; Mice; Pentobarbit

1989
[The effect of pentobarbital and pargyline on the development of acute experimental intracranial hypertension in chick embryos].
    Sbornik lekarsky, 1987, Volume: 89, Issue:10

    Topics: Acute Disease; Animals; Asphyxia; Brain Edema; Chick Embryo; Intracranial Pressure; Pargyline; Pento

1987
Effects of ACTH, dexamethasone and asphyxia on electrical activity of the rat hypothalamus.
    Brain research, 1968, Aug-26, Volume: 10, Issue:2

    Topics: Adrenalectomy; Adrenocorticotropic Hormone; Anesthesia; Animals; Asphyxia; Behavior, Animal; Dexamet

1968
Effects of conditioning afferent volleys on variability of monosynaptic responses of extensor motoneurons.
    Journal of neurophysiology, 1969, Volume: 32, Issue:2

    Topics: Analysis of Variance; Animals; Asphyxia; Cats; Computers, Analog; Electric Stimulation; Electrophysi

1969
The effect of thiazide on the sympathetic nervous system of hypertensive rats.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 177, Issue:2

    Topics: Anesthetics; Angiotensin II; Animals; Asphyxia; Body Weight; Epinephrine; Hindlimb; Hypertension, Re

1969
The effects of lethal procedures on the histochemical localization of acid hydrolases.
    Histochemie. Histochemistry. Histochimie, 1973, Oct-26, Volume: 37, Issue:2

    Topics: Acid Phosphatase; Animals; Asphyxia; Chloroform; Cricetinae; Ethyl Ethers; Galactosidases; Glucuroni

1973
Expiratory versus inspiratory efforts in suffocating pigeons.
    Agents and actions, 1972, Volume: 2, Issue:4

    Topics: Animals; Asphyxia; Codeine; Columbidae; Cyclobutanes; Ethylamines; Female; Male; Noscapine; Pentobar

1972
[Splanchnic-motor reflex with its reflex center in the brain stem].
    No to shinkei = Brain and nerve, 1970, May-01, Volume: 22, Issue:5

    Topics: Action Potentials; Animals; Asphyxia; Brain Stem; Cats; Decerebrate State; Motor Neurons; Pentobarbi

1970
On the organization of the auditory cortex. IV. The spread of the direct cortical response in adult cats.
    Acta physiologica latino americana, 1965, Volume: 15, Issue:2

    Topics: Animals; Asphyxia; Cats; Cerebral Cortex; Electrophysiology; Neural Conduction; Pentobarbital

1965
Electrical impedance and vasomotor changes accompanying synaptic transmission in sympathetic ganglia.
    Experimental neurology, 1966, Volume: 15, Issue:1

    Topics: Animals; Asphyxia; Cats; Decerebrate State; Electrocardiography; Extracellular Space; Fatigue; Femor

1966
The development of the adrenal medulla of the foetal and new-born calf.
    The Journal of physiology, 1966, Volume: 183, Issue:2

    Topics: Acetylcholine; Adrenal Medulla; Animals; Animals, Newborn; Asphyxia; Blood Gas Analysis; Cattle; Epi

1966