pentobarbital has been researched along with Subarachnoid Hemorrhage in 13 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
Subarachnoid Hemorrhage: Bleeding into the intracranial or spinal SUBARACHNOID SPACE, most resulting from INTRACRANIAL ANEURYSM rupture. It can occur after traumatic injuries (SUBARACHNOID HEMORRHAGE, TRAUMATIC). Clinical features include HEADACHE; NAUSEA; VOMITING, nuchal rigidity, variable neurological deficits and reduced mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Induced pentobarbital coma for the management of increased intracranial pressure is one such intervention, required to maintain patient stability." | 7.69 | Therapeutic Intervention Scoring System used in the care of patients in pentobarbital-induced coma to determine nurse-patient ratios. ( Bucholz, RD; Gomez, CR; Malkoff, MD; Myles, GL; Perry, AG, 1996) |
| " Pentobarbital and verapamil produced concentration-dependent vasodilation in segments of middle cerebral artery of either control or exposed to experimental subarachnoid hemorrhage (SAH) cats precontracted with 5-hydroxytryptamine (5-HT, 10(-5) M) or K+ (75 mM), the potency to evoke relaxation being greater for verapamil than pentobarbital." | 7.67 | Interference of pentobarbital and verapamil with the reactivity of middle cerebral artery of cat exposed to experimental subarachnoid hemorrhage. ( Marín, J; Martinez-Aldama, J; Salaices, M, 1989) |
| " Induced pentobarbital coma for the management of increased intracranial pressure is one such intervention, required to maintain patient stability." | 3.69 | Therapeutic Intervention Scoring System used in the care of patients in pentobarbital-induced coma to determine nurse-patient ratios. ( Bucholz, RD; Gomez, CR; Malkoff, MD; Myles, GL; Perry, AG, 1996) |
| " Pentobarbital and verapamil produced concentration-dependent vasodilation in segments of middle cerebral artery of either control or exposed to experimental subarachnoid hemorrhage (SAH) cats precontracted with 5-hydroxytryptamine (5-HT, 10(-5) M) or K+ (75 mM), the potency to evoke relaxation being greater for verapamil than pentobarbital." | 3.67 | Interference of pentobarbital and verapamil with the reactivity of middle cerebral artery of cat exposed to experimental subarachnoid hemorrhage. ( Marín, J; Martinez-Aldama, J; Salaices, M, 1989) |
| "Seizures were detected in 19% (n = 110) of patients who underwent cEEG monitoring; the seizures were exclusively nonconvulsive in 92% (n = 101) of these patients." | 2.42 | Detection of electrographic seizures with continuous EEG monitoring in critically ill patients. ( Claassen, J; Emerson, RG; Hirsch, LJ; Kowalski, RG; Mayer, SA, 2004) |
| "Ninety-two cerebral aneurysm cases treated by clipping under moderate hypothermia are reviewed." | 1.27 | Barbiturates for cerebral aneurysm surgery. A review of preliminary results. ( Beks, JW; Belopavlovic, M; Buchthal, A, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (61.54) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Connolly, M | 2 |
| Liou, R | 1 |
| Vespa, P | 2 |
| Hu, X | 2 |
| SUZUKI, K | 1 |
| KOREY, SR | 1 |
| TERRY, RD | 1 |
| Claassen, J | 1 |
| Mayer, SA | 1 |
| Kowalski, RG | 1 |
| Emerson, RG | 1 |
| Hirsch, LJ | 1 |
| Tsuchiya, J | 1 |
| Ito, Y | 1 |
| Hino, T | 1 |
| Ohashi, H | 1 |
| Kunieda, T | 1 |
| Sakata, K | 1 |
| Myles, GL | 1 |
| Malkoff, MD | 1 |
| Perry, AG | 1 |
| Bucholz, RD | 1 |
| Gomez, CR | 1 |
| Lavine, SD | 1 |
| Masri, LS | 1 |
| Levy, ML | 1 |
| Giannotta, SL | 1 |
| Marín, J | 1 |
| Martinez-Aldama, J | 1 |
| Salaices, M | 1 |
| Hayashi, M | 2 |
| Kobayashi, H | 1 |
| Kawano, H | 1 |
| Handa, Y | 1 |
| Kabuto, M | 1 |
| Belopavlovic, M | 1 |
| Buchthal, A | 1 |
| Beks, JW | 1 |
| McIntyre, JW | 2 |
| Miller, JD | 2 |
| Weir, BK | 1 |
| Dobson, D | 1 |
| Yamamoto, S | 1 |
| Yamamoto, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective Trial of Nonconvulsive Electrographic Seizure Detection by Nurses in the Adult Neuro ICU Using a Panel of Quantitative EEG Trends[NCT02082873] | 20 participants (Actual) | Observational | 2015-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pentobarbital and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
Detection of electrographic seizures with continuous EEG monitoring in critically ill patients.
Topics: Adult; Aged; Anticonvulsants; Brain Diseases; Child; Child, Preschool; Cohort Studies; Coma; Conscio | 2004 |
12 other studies available for pentobarbital and Subarachnoid Hemorrhage
| Article | Year |
|---|---|
Identification of an Intracranial Pressure (ICP) Response Function from Continuously Acquired Electroencephalographic and ICP Signals in Burst-Suppressed Patients.
Topics: Adult; Aneurysm, Ruptured; Brain Injuries, Traumatic; Brain Waves; Electroencephalography; Female; G | 2016 |
Characterization of Cerebral Vascular Response to EEG Bursts Using ICP Pulse Waveform Template Matching.
Topics: Adult; Aneurysm, Ruptured; Brain Injuries, Traumatic; Brain Waves; Cerebrovascular Circulation; Elec | 2016 |
STUDIES ON PROTEIN SYNTHESIS IN BRAIN MICROSOMAL SYSTEM.
Topics: Amino Acids; Biomedical Research; Brain; Brain Diseases; Brain Neoplasms; Dementia; Electrons; Ether | 1964 |
Stress ulcer accompanying subarachnoid hemorrhage--a new rat model.
Topics: Animals; Cimetidine; Diazepam; Disease Models, Animal; Gastric Mucosa; Male; Pentobarbital; Phenytoi | 1983 |
Therapeutic Intervention Scoring System used in the care of patients in pentobarbital-induced coma to determine nurse-patient ratios.
Topics: Adult; Cerebrovascular Disorders; Coma; Female; Humans; Hypnotics and Sedatives; Intracranial Pressu | 1996 |
Temporary occlusion of the middle cerebral artery in intracranial aneurysm surgery: time limitation and advantage of brain protection.
Topics: Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Aneurysm, Ruptured; Brai | 1997 |
Interference of pentobarbital and verapamil with the reactivity of middle cerebral artery of cat exposed to experimental subarachnoid hemorrhage.
Topics: Animals; Cats; Cerebral Arteries; Female; Male; Pentobarbital; Potassium; Subarachnoid Hemorrhage; V | 1989 |
The effects of local intraparenchymal pentobarbital on intracranial hypertension following experimental subarachnoid hemorrhage.
Topics: Animals; Dogs; Hypothalamus, Posterior; Injections; Intracranial Pressure; Medulla Oblongata; Pentob | 1987 |
Barbiturates for cerebral aneurysm surgery. A review of preliminary results.
Topics: Arterial Occlusive Diseases; Brain; Cerebral Angiography; Cerebrovascular Disorders; Hemodynamics; H | 1985 |
Anaesthesia for cerebral angiography: cardiovascular and cerebrospinal fluid pressure observations in the monkey under pentobarbital-halothane anaesthesia.
Topics: Anesthesia, General; Animals; Blood Pressure; Catheterization; Cerebral Angiography; Cerebrospinal F | 1969 |
Simulated subarachnoid haemorrhage in monkeys under pentobarbital-halothane anaesthesia, with particular reference to monitoring during cerebral angiography.
Topics: Acid-Base Equilibrium; Anesthesia, General; Animals; Blood Pressure; Body Temperature; Cerebral Angi | 1969 |
[Acute intracranial hypertension].
Topics: Adult; Aged; Betamethasone; Blood Pressure; Brain Edema; Cerebrospinal Fluid; Chlorpromazine; Electr | 1971 |