pentobarbital has been researched along with Spinal Cord Injuries in 11 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
Spinal Cord Injuries: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pulmonary index (100 x wet lung weight/body weight) was 0." | 1.33 | Importance of anesthesia for the genesis of neurogenic pulmonary edema in spinal cord injury. ( Borges, G; Cambiucci, EC; de Almeida, AR; Gontijo, JA; Leal Filho, MB; Metze, K; Morandin, RC, 2005) |
| "Late halothane treatment was ineffective when given as early as 10 minutes postinjury while both the electrophysiological and hemodynamic effects of halothane vs." | 1.29 | Halothane anesthesia is neuroprotective in experimental spinal cord injury: early hemodynamic mechanisms of action. ( Agresta, CA; Kelly, G; Lee, WA; Mendez, AA; Sabato, S; Salzman, SK, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, JA | 1 |
| Bopp, AC | 1 |
| Henwood, MK | 1 |
| Bean, P | 1 |
| Grau, JW | 2 |
| Nout, YS | 1 |
| Beattie, MS | 1 |
| Bresnahan, JC | 1 |
| Ho, SM | 1 |
| Waite, PM | 1 |
| Tetik, O | 1 |
| Islamoğlu, F | 1 |
| Göncü, T | 1 |
| Cekirdekçi, A | 1 |
| Büket, S | 1 |
| Leal Filho, MB | 1 |
| Morandin, RC | 1 |
| de Almeida, AR | 1 |
| Cambiucci, EC | 1 |
| Borges, G | 1 |
| Gontijo, JA | 1 |
| Metze, K | 1 |
| Washburn, SN | 1 |
| Patton, BC | 1 |
| Ferguson, AR | 1 |
| Hudson, KL | 1 |
| Salzman, SK | 2 |
| Lee, WA | 2 |
| Sabato, S | 2 |
| Mendez, AA | 2 |
| Agresta, CA | 2 |
| Kelly, G | 1 |
| Duke, M | 1 |
| Advokat, C | 1 |
| Parker, AJ | 1 |
| Ingersoll, EB | 1 |
| Choi, IH | 1 |
| Fonseca, AS | 1 |
| Freeman, GM | 1 |
| Feldman, H | 1 |
| Hillman, H | 1 |
11 other studies available for pentobarbital and Spinal Cord Injuries
| Article | Year |
|---|---|
General Anesthesia Blocks Pain-Induced Hemorrhage and Locomotor Deficits After Spinal Cord Injury in Rats.
Topics: Anesthesia, General; Anesthetics; Animals; Contusions; Hemorrhage; Humans; Isoflurane; Pain; Pentoba | 2023 |
Severity of locomotor and cardiovascular derangements after experimental high-thoracic spinal cord injury is anesthesia dependent in rats.
Topics: Anesthetics; Animals; Blood Pressure; Cardiovascular System; Disease Models, Animal; Female; Heart R | 2012 |
Effects of different anesthetics on the paired-pulse depression of the h reflex in adult rat.
Topics: Administration, Inhalation; Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Disease Models, Ani | 2002 |
Reduction of spinal cord injury with pentobarbital and hypothermia in a rabbit model.
Topics: Adjuvants, Anesthesia; Animals; Disease Models, Animal; Hypothermia, Induced; Pentobarbital; Rabbits | 2002 |
Importance of anesthesia for the genesis of neurogenic pulmonary edema in spinal cord injury.
Topics: Anesthetics, General; Animals; Blood Pressure; Ketamine; Lung; Microscopy, Electron, Transmission; P | 2005 |
Exposure to intermittent nociceptive stimulation under pentobarbital anesthesia disrupts spinal cord function in rats.
Topics: Animals; Behavior, Animal; Conditioning, Operant; Electroshock; Hindlimb; Hypnotics and Sedatives; M | 2007 |
Halothane anesthesia is neuroprotective in experimental spinal cord injury: early hemodynamic mechanisms of action.
Topics: Anesthesia, Inhalation; Animals; Drug Interactions; Evoked Potentials, Somatosensory; Halothane; Hem | 1993 |
Pentobarbital-induced modulation of flexor and H-reflexes in spinal rats.
Topics: Adjuvants, Anesthesia; Animals; Baclofen; Electric Stimulation; H-Reflex; Male; Muscle Relaxants, Ce | 2000 |
Comparison of the averaged evoked cisterna cerebellomedullaris potential, cortical potential, and neurologic examination in the diagnosis of spinal cord injury of the dog.
Topics: Anesthesia; Animals; Cerebral Cortex; Dog Diseases; Dogs; Evoked Potentials; Female; Male; Neurologi | 1978 |
Anesthesia influences the outcome from experimental spinal cord injury.
Topics: Anesthesia; Animals; Blood Pressure; Evoked Potentials, Somatosensory; Halothane; Male; Nitrous Oxid | 1990 |
A clinical description of death in rats and the effect of various conditions on the time untile cessation of ventricular contraction following section between the brain and spinal cord.
Topics: Age Factors; Animals; Animals, Newborn; Brain; Death; Electrocardiography; Female; Heart; Heart Vent | 1969 |