pentobarbital has been researched along with Shock, Septic in 11 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| "coli bacteremia was studied in rats and compared to the effect of two other anesthetic procedures in previously published studies." | 1.30 | E. Coli bacteremia-induced changes in the skeletal muscle microcirculation vary with anesthetics. ( Garrison, RN; Harris, PD; Lüebbe, AS, 1998) |
| "Therefore, data obtained from septic shock studies applying pentobarbital have to be evaluated carefully." | 1.27 | Comparison of ketamine and pentobarbital anesthesia with the conscious state in a porcine model of Pseudomonas aeruginosa septicemia. ( Blümel, G; Pfeiffer, UJ; Worek, FS; Zeravik, J; Zimmermann, GJ, 1988) |
| " A dose-response curve to NE, ANG II, and lysine vasopressin was also performed." | 1.27 | Angiotensin II, vasopressin, and sympathetic activity in conscious rats with endotoxemia. ( Brunner, HR; Nussberger, J; Schaller, MD; Waeber, B, 1985) |
| "During endotoxin shock, the cardiovascular effects of gentamicin and tobramycin were relatively more pronounced (sometimes more than doubled) than effects observed during the control state." | 1.26 | Cardiovascular manifestations of acute antibiotic toxicity during E coli endotoxin shock in anesthetized dogs. ( Adams, HR; Mathew, BP; Parker, JL, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (90.91) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| KOBOLD, EE | 1 |
| LOVELL, R | 1 |
| KATZ, W | 1 |
| THAL, AP | 1 |
| CORRADO, AP | 1 |
| LIMA, EG | 1 |
| ROTHSCHILD, AM | 1 |
| Archer, LT | 2 |
| White, GL | 2 |
| Beller-Todd, B | 2 |
| Elmore, OF | 1 |
| Glasgow, JS | 1 |
| Hinshaw, LB | 2 |
| Elmore, O | 1 |
| Lüebbe, AS | 1 |
| Harris, PD | 1 |
| Garrison, RN | 1 |
| Halinen, MO | 1 |
| Hakumäki, MO | 1 |
| Sarajas, HS | 1 |
| Adams, HR | 1 |
| Parker, JL | 1 |
| Mathew, BP | 1 |
| Worek, FS | 1 |
| Blümel, G | 1 |
| Zeravik, J | 1 |
| Zimmermann, GJ | 1 |
| Pfeiffer, UJ | 1 |
| Schaller, MD | 1 |
| Waeber, B | 1 |
| Nussberger, J | 1 |
| Brunner, HR | 1 |
| Zeppa, R | 1 |
| Fronek, K | 1 |
| Zweifach, BW | 1 |
11 other studies available for pentobarbital and Shock, Septic
| Article | Year |
|---|---|
CHEMICAL MEDIATORS RELEASED BY ENDOTOXIN.
Topics: Animals; Catecholamines; Dogs; Endotoxins; Histamine; Histamine Release; Injections; Injections, Int | 1964 |
STUDY OF THE MECHANISM OF THE CARDIOVASCULAR SHOCK PRODUCED BY ENDOTOXIN OF GRAM-NEGATIVE BACTERIA: E. COLI AND S. TYPHII.
Topics: Cardiovascular System; Dogs; Endotoxins; Escherichia coli; Histamine Release; Pentobarbital; Povidon | 1964 |
Does sodium pentobarbital anesthesia compromise phagocytosis of E coli in vitro?
Topics: Anesthesia; Animals; Dogs; Escherichia coli; Female; Glucose; In Vitro Techniques; Male; Neutrophils | 1980 |
Does sodium pentobarbital anesthesia compromise clearance of bacteria or survival of dogs in lethal E coli shock?
Topics: Anesthesia; Animals; Bacterial Toxins; Blood Glucose; Dogs; Escherichia coli; Pentobarbital; Phagocy | 1981 |
E. Coli bacteremia-induced changes in the skeletal muscle microcirculation vary with anesthetics.
Topics: Anesthetics; Animals; Bacteremia; Chloralose; Decerebrate State; Disease Models, Animal; Escherichia | 1998 |
Suppresion of autonomic postganglionic discharges by pentobarbital in dogs, with or without endotoxemia.
Topics: Action Potentials; Afferent Pathways; Animals; Autonomic Fibers, Postganglionic; Blood Pressure; Dog | 1978 |
Cardiovascular manifestations of acute antibiotic toxicity during E coli endotoxin shock in anesthetized dogs.
Topics: Animals; Anti-Bacterial Agents; Cephalothin; Depression, Chemical; Dogs; Dose-Response Relationship, | 1979 |
Comparison of ketamine and pentobarbital anesthesia with the conscious state in a porcine model of Pseudomonas aeruginosa septicemia.
Topics: Anesthesia, Intravenous; Animals; Female; Hemodynamics; Ketamine; Male; Pentobarbital; Pseudomonas I | 1988 |
Angiotensin II, vasopressin, and sympathetic activity in conscious rats with endotoxemia.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Captopril; Endotoxins; Epinephrine; M | 1985 |
The elusive trigger mechanism of endotoxin shock.
Topics: Animals; Blood Pressure; Blood Pressure Determination; Catecholamines; Chloralose; Dogs; Endotoxins; | 1967 |
Cardiovascular responses to bacterial endotoxin in anesthetized and nonanesthetized animals.
Topics: Anesthesia; Angiotensin II; Animals; Arteries; Blood Flow Velocity; Blood Pressure; Cardiac Output; | 1972 |