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pentobarbital and Rhabdomyolysis

pentobarbital has been researched along with Rhabdomyolysis in 3 studies

Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.

Rhabdomyolysis: Necrosis or disintegration of skeletal muscle often followed by myoglobinuria.

Research Excerpts

ExcerptRelevanceReference
" Posttreatment with pentobarbital decreased blood BUN, Cre, GOT, GPT, CPK levels, decreased the markers of kidney injury, and suppressed the release of NF-kappaB and iNOS after rhabdomyolysis."7.75Pentobarbital reduces rhabdomyolysis-induced acute renal failure in conscious rats. ( Hsu, BG; Lee, CJ; Lee, RP; Subeq, YM; Wu, WT; Yang, FL, 2009)
" Posttreatment with pentobarbital decreased blood BUN, Cre, GOT, GPT, CPK levels, decreased the markers of kidney injury, and suppressed the release of NF-kappaB and iNOS after rhabdomyolysis."3.75Pentobarbital reduces rhabdomyolysis-induced acute renal failure in conscious rats. ( Hsu, BG; Lee, CJ; Lee, RP; Subeq, YM; Wu, WT; Yang, FL, 2009)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Subeq, YM1
Wu, WT1
Lee, CJ1
Lee, RP1
Yang, FL1
Hsu, BG1
Byrav, P1
Medhi, B1
Kaur, H1
Prakash, A1
Lochhead, KM1
Kharasch, ED1
Zager, RA1

Other Studies

3 other studies available for pentobarbital and Rhabdomyolysis

ArticleYear
Pentobarbital reduces rhabdomyolysis-induced acute renal failure in conscious rats.
    The Journal of trauma, 2009, Volume: 67, Issue:1

    Topics: Acute Kidney Injury; Animals; Cognition; Disease Models, Animal; Follow-Up Studies; GABA Modulators;

2009
Pentobarbital in the treatment of rhabdomyolysis-induced acute renal failure?
    The Journal of trauma, 2010, Volume: 68, Issue:3

    Topics: Acute Kidney Injury; Animals; GABA Modulators; Pentobarbital; Rats; Rhabdomyolysis

2010
Anesthetic effects on the glycerol model of rhabdomyolysis-induced acute renal failure in rats.
    Journal of the American Society of Nephrology : JASN, 1998, Volume: 9, Issue:2

    Topics: Acute Kidney Injury; Anesthetics, Inhalation; Animals; Creatine Kinase; Creatinine; Desflurane; Glyc

1998