pentobarbital has been researched along with Reperfusion Injury in 9 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "These results indicate that activation of GABAA receptors, which include the specific binding subunits for propofol and midazolam, but not pentobarbital, plays a role in the inhibition of neuronal death induced by brain ischemia." | 7.70 | Neuroprotective properties of propofol and midazolam, but not pentobarbital, on neuronal damage induced by forebrain ischemia, based on the GABAA receptors. ( Isshiki, A; Ito, H; Uchino, H; Watanabe, Y, 1999) |
| "These results indicate that activation of GABAA receptors, which include the specific binding subunits for propofol and midazolam, but not pentobarbital, plays a role in the inhibition of neuronal death induced by brain ischemia." | 3.70 | Neuroprotective properties of propofol and midazolam, but not pentobarbital, on neuronal damage induced by forebrain ischemia, based on the GABAA receptors. ( Isshiki, A; Ito, H; Uchino, H; Watanabe, Y, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bauer, TM | 1 |
| Giles, AV | 1 |
| Sun, J | 1 |
| Femnou, A | 1 |
| Covian, R | 1 |
| Murphy, E | 1 |
| Balaban, RS | 1 |
| Petric, S | 1 |
| Clasen, L | 1 |
| van Wessel, C | 1 |
| Geduldig, N | 1 |
| Ding, Z | 1 |
| Schullenberg, M | 1 |
| Mersmann, J | 1 |
| Zacharowski, K | 1 |
| Aller, MI | 1 |
| Schmidt, KG | 1 |
| Donner, BC | 1 |
| Adachi, N | 1 |
| Liu, K | 1 |
| Motoki, A | 1 |
| Hiraga, N | 1 |
| Irisawa, Y | 1 |
| Semba, K | 1 |
| Arai, T | 1 |
| Myers, SI | 1 |
| Hernandez, R | 1 |
| Miller, TA | 1 |
| Thorniley, MS | 2 |
| Lane, NJ | 1 |
| Manek, S | 1 |
| Green, CJ | 2 |
| Lane, N | 1 |
| Simpkin, S | 1 |
| Fuller, B | 1 |
| Jenabzadeh, MZ | 1 |
| Ito, H | 1 |
| Watanabe, Y | 1 |
| Isshiki, A | 1 |
| Uchino, H | 1 |
| Clark, SC | 1 |
| Sudarshan, CD | 1 |
| Khanna, R | 1 |
| Roughan, JV | 1 |
| Flecknell, PA | 1 |
| Dark, JH | 1 |
| Schettini, A | 1 |
| Lippman, RH | 1 |
| Walsh, EK | 1 |
9 other studies available for pentobarbital and Reperfusion Injury
| Article | Year |
|---|---|
Perfused murine heart optical transmission spectroscopy using optical catheter and integrating sphere: Effects of ischemia/reperfusion.
Topics: Animals; Heart; Heparin; Injections, Intraperitoneal; Least-Squares Analysis; Mice; Mice, Inbred C57 | 2019 |
In vivo electrophysiological characterization of TASK-1 deficient mice.
Topics: Adrenergic beta-Agonists; Anesthetics; Animals; Atrial Function; Baroreflex; Electric Stimulation; E | 2012 |
A comparison of protective effects between L-histidine and hypothermia against ischemia-induced neuronal damage in gerbil hippocampus.
Topics: Animals; Brain Ischemia; Drug Therapy, Combination; Gerbillinae; Hippocampus; Histamine; Histamine A | 2006 |
Differing effects of anesthetics on splanchnic arterial blood flow during hemorrhagic shock.
Topics: Anesthetics; Animals; Aorta; Blood Pressure; In Vitro Techniques; Mesenteric Artery, Superior; Metho | 1994 |
Non-invasive measurement of respiratory chain dysfunction following hypothermic renal storage and transplantation.
Topics: Animals; Cell Survival; Electron Transport; Electron Transport Complex IV; Kidney; Kidney Transplant | 1994 |
Monitoring of mitochondrial NADH levels by surface fluorimetry as an indication of ischaemia during hepatic and renal transplantation.
Topics: Animals; Female; Ischemia; Kidney Transplantation; Kinetics; Liver Transplantation; Male; Mitochondr | 1996 |
Neuroprotective properties of propofol and midazolam, but not pentobarbital, on neuronal damage induced by forebrain ischemia, based on the GABAA receptors.
Topics: Anesthetics, Intravenous; Animals; Baclofen; Brain Ischemia; Dose-Response Relationship, Drug; GABA | 1999 |
A new porcine model of reperfusion injury after lung transplantation.
Topics: Animals; Azaperone; Disease Models, Animal; Female; Hypnotics and Sedatives; Lung Transplantation; P | 1999 |
Attenuation of decompressive hypoperfusion and cerebral edema by superoxide dismutase.
Topics: Animals; Blood Pressure; Blood-Brain Barrier; Body Water; Brain; Brain Edema; Carbon Dioxide; Cerebr | 1989 |