pentobarbital has been researched along with Postoperative Nausea and Vomiting in 1 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
Postoperative Nausea and Vomiting: Emesis and queasiness occurring after anesthesia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propofol may produce its antiemetic effect by depleting the area postrema of serotonin as well as by a direct gamma-aminobutyric acid-mediated inhibition." | 1.31 | The effects of propofol in the area postrema of rats. ( Cechetto, DF; Diab, T; Gelb, AW; Gibson, CJ, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cechetto, DF | 1 |
| Diab, T | 1 |
| Gibson, CJ | 1 |
| Gelb, AW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Optimizing Anesthesia Antiemetic Measures Versus Combination With Dexamethasone or Ondansetron in the Prevention of Postoperative Nausea and Vomiting.[NCT00825071] | Phase 4 | 180 participants (Actual) | Interventional | 2007-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 other study available for pentobarbital and Postoperative Nausea and Vomiting
| Article | Year |
|---|---|
The effects of propofol in the area postrema of rats.
Topics: Anesthetics, Intravenous; Animals; Electric Stimulation; Electrophysiology; Fourth Ventricle; GABA-A | 2001 |