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pentobarbital and Poisoning

pentobarbital has been researched along with Poisoning in 35 studies

Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.

Poisoning: Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.

Research Excerpts

ExcerptRelevanceReference
" PROSPECTIVE CONTROLLED CLINICAL TRIALS: Two of the 94 publications were prospective controlled studies (only one stated that allocation was via blinded randomisation), and both assessed the effect of multiple-dose activated charcoal for acute phenobarbital poisoning."4.87Enhanced elimination in acute barbiturate poisoning - a systematic review. ( Buckley, NA; Roberts, DM, 2011)
"Assay of the clinical course of poisoning with acetic acid, dichloroethane, carbophos, chlorophos, phenobarbital and sodium etaminal in 2538 patients made it possible to define, with the use of the probit analysis, the 25, 50, 75 and 95% concentration thresholds of the lethality in acute poisonings with acetic acid, carbophos and dichloroethane."3.67[Age-related aspects of intensive therapy of acute poisoning of chemical etiology]. ( Dagaev, VN; Gorin, EE; Kostomarova, LG; Luzhnikov, EA, 1985)
" It is concluded that haemoperfusion through this column is a safe and simple procedure, which merits evaluation in the treatment of severe drug overdose in man."1.26The safety assessment in the dog of a charcoal haemoperfusion column. ( Fennimore, J; Kolthammer, JC; Lang, S; Watson, PA, 1976)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199031 (88.57)18.7374
1990's3 (8.57)18.2507
2000's0 (0.00)29.6817
2010's1 (2.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Roberts, DM1
Buckley, NA1
LACKEY, RW1
BAILEY, HA1
GOTH, A1
LARSON, E1
WYNN, MF1
ADAMS, JP1
SATOSKAR, RS1
TRIVEDI, JC1
HIRAKI, K1
HYODO, K1
SKOELD, G1
BRUNK, U1
ZAVON, MR1
BALZEREIT, F1
ARNOLD, W1
TARSITANO, JJ1
Smith, RP1
Gosselin, RE1
Henderson, JA1
Anderson, DM1
Cruz, IA1
Cramer, NC1
Parrish, AE1
Lurie, JB1
Sergienko, VI1
Grigor'eva, AV1
Artemkina, IV1
Bul'chuk, OV1
Lopukhin, IuM1
Bironneau, E1
Garrec, F1
Kergueris, MF1
Testa, A1
Nicolas, F1
Yoshida, SH1
Siu, J1
Griffey, SM1
German, JB1
Gershwin, ME1
Rosenbaum, JL1
Kramer, MS1
Raja, R1
Rodríguez Olleros, A1
Dietrich, R1
Taveras, JE1
Kolthammer, JC1
Watson, PA1
Lang, S1
Fennimore, J1
Hill, JB1
Palaia, FL1
McAdams, JL1
Palmer, PJ1
Maret, SM1
Dinovo, EC1
Gottschalk, LA1
Bures, J1
Buresova, O1
Luzhnikov, EA1
Dagaev, VN1
Kostomarova, LG1
Gorin, EE1
Gröschel, D1
Gerstein, AR1
Rosenbaum, JM1
Medd, RK1
Widdop, B1
Braithwaite, RA1
Rees, AJ1
Goulding, R1
Picchioni, AL4
Chin, L4
Laird, HE1
Hulting, J1
Thorstrand, C1
Allen, JR1
Chesney, CF1
Frazee, WJ1
Chang, TM1
Gonda, A1
Dirks, JH1
Malave, N1
Duplisse, BR1
Thompson, RE1
Akers, TK1
Iaroslavskiĭ, AA1
Firsov, NN1
Koldaev, AA1
Fine, RN1
Stiles, Q1
DePalma, JR1
Donnell, GN1
Rosenbaum, BJ1
Alfrey, AC1
Holmes, JH1
Verhulst, HL1
Dieterle, B1
Henderson, ML1

Reviews

2 reviews available for pentobarbital and Poisoning

ArticleYear
Enhanced elimination in acute barbiturate poisoning - a systematic review.
    Clinical toxicology (Philadelphia, Pa.), 2011, Volume: 49, Issue:1

    Topics: Acute Disease; Adult; Barbiturates; Clinical Trials as Topic; Female; Humans; Pentobarbital; Phenoba

2011
Hemodiafiltration in pentobarbital poisoning.
    Renal failure, 1996, Volume: 18, Issue:2

    Topics: Acute Disease; Adult; Fatal Outcome; Hemodiafiltration; Humans; Hypnotics and Sedatives; Male; Pento

1996

Other Studies

33 other studies available for pentobarbital and Poisoning

ArticleYear
The use of peritoneal lavage in treatment of experimental pentobarbital poisoning.
    Texas reports on biology and medicine, 1953, Volume: 12, Issue:1

    Topics: Barbiturates; Pentobarbital; Peritoneal Lavage; Poisoning

1953
Studies of pentobarbital depression.
    Anesthesiology, 1954, Volume: 15, Issue:5

    Topics: Barbiturates; Depression; Depressive Disorder; Humans; Pentobarbital; Pentylenetetrazole; Poisoning;

1954
Effect of hydrocortisone on acute pentobarbital toxicity in mice.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1955, Volume: 89, Issue:4

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Animals; Barbiturates; Hydrocortisone; Mice; Pentobarbital;

1955
[ON POISONING WITH ORGANIC CHLORINE AGRICULTURAL PREPARATIONS--BASIC AND CLINICAL ASPECTS OF THE -DRIN PREPARATIONS].
    [Chiryo] [Therapy], 1964, Volume: 46

    Topics: Chlorine; Dieldrin; Insecticides; Ions; Organic Agriculture; Pentobarbital; Phenobarbital; Physiolog

1964
EFFECT OF MODE OF SACRIFICE ON HISTOCHEMICALLY DEMONSTRABLE ACTIVITY ON UNSPECIFIC ESTERASES AND UNSPECIFIC ALKALINE MONOPHOSPHATASES IN GOLDEN HAMSTERS.
    Acta pathologica et microbiologica Scandinavica, 1964, Volume: 61

    Topics: Adrenal Glands; Adrenal Medulla; Alkaline Phosphatase; Animals; Barbiturates; Carbon Monoxide Poison

1964
CHLORINATED HYDROCARBON INSECTICIDES. INTOXICATION AND GUIDE TO TREATMENT.
    JAMA, 1964, Nov-16, Volume: 190

    Topics: Antidotes; Calcium; Chlordan; DDT; Diagnosis; Dieldrin; Emetics; Gastric Lavage; Gluconates; Humans;

1964
[PULMONARY EDEMA AND PENTOBARBITAL POISONING].
    Der Nervenarzt, 1965, Volume: 36

    Topics: Pentobarbital; Poisoning; Pulmonary Edema; Toxicology

1965
CHILDREN, DRUGS AND LOCAL ANESTHESIA.
    Journal of the American Dental Association (1939), 1965, Volume: 70

    Topics: Anesthesia; Anesthesia, Dental; Anesthesia, Local; Child; Humans; Malpractice; Meperidine; Mepivacai

1965
Comparison of the adsorptive properties of activated charcoal and Alaskan montmorillonite for some common poisons.
    Toxicology and applied pharmacology, 1967, Volume: 10, Issue:1

    Topics: Adsorption; Aluminum Silicates; Charcoal; Dextroamphetamine; Ethanol; Humans; Hydrogen-Ion Concentra

1967
Hemodialysis in chlordiazepoxide toxicity.
    JAMA, 1967, Oct-30, Volume: 202, Issue:5

    Topics: Adult; Alcoholic Intoxication; Amobarbital; Chlordiazepoxide; Dextropropoxyphene; Ethchlorvynol; Fem

1967
The management of poisoning with an organophorphorus (op) insecticide.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1967, Oct-21, Volume: 41, Issue:40

    Topics: Atropine; Drainage; Humans; Insecticides; Parathion; Pentobarbital; Phosphorus; Poisoning; Pyridiniu

1967
[The protective action of sodium hypochlorite on the morphology and transcription of the central neurons in rats with acute nembutal poisoning].
    Biulleten' eksperimental'noi biologii i meditsiny, 1993, Volume: 116, Issue:12

    Topics: Acute Disease; Animals; Brain; Drug Evaluation, Preclinical; Male; Neurons; Pentobarbital; Poisoning

1993
Dietary Juniperis virginiensis seed oil decreased pentobarbital-associated mortalities among DBA/1 mice treated with collagen-adjuvant emulsions.
    Journal of lipid mediators and cell signalling, 1996, Volume: 13, Issue:3

    Topics: Animals; Arthritis, Experimental; CD4-CD8 Ratio; Collagen; Dietary Fats, Unsaturated; Humans; Infant

1996
Resin hemoperfusion for acute drug intoxication.
    Archives of internal medicine, 1976, Volume: 136, Issue:3

    Topics: Adult; Aged; Amobarbital; Female; Flurazepam; Glutethimide; Humans; Middle Aged; Pentobarbital; Pois

1976
[Sensitivity of the antitoxic liver function. Experimental demonstration].
    Boletin de la Asociacion Medica de Puerto Rico, 1976, Volume: 68, Issue:7

    Topics: Acetamides; Animals; Dogs; Liver; Liver Function Tests; Pentobarbital; Phenobarbital; Poisoning; Thi

1976
The safety assessment in the dog of a charcoal haemoperfusion column.
    Clinical science and molecular medicine, 1976, Volume: 51, Issue:6

    Topics: Acetaminophen; Animals; Carbon; Charcoal; Chromatography, Gas; Dogs; Pentobarbital; Poisoning; Renal

1976
Efficacy of activated charcoal hemoperfusion in removing lethal doses of barbiturates and salicylate from the blood of rats and dogs.
    Clinical chemistry, 1976, Volume: 22, Issue:6

    Topics: Animals; Barbiturates; Charcoal; Disease Models, Animal; Dogs; Pentobarbital; Perfusion; Phenobarbit

1976
Results of a nine-laboratory survey of forensic toxicology proficiency.
    Clinical chemistry, 1976, Volume: 22, Issue:6

    Topics: Ethanol; Forensic Medicine; Glutethimide; Humans; Narcotics; Pentobarbital; Phenobarbital; Poisoning

1976
Conditioned taste aversion to injected flavor: differential effect of anesthesia on the formation of the gustatory trace and on its association with poisoning in rats.
    Neuroscience letters, 1989, Apr-10, Volume: 98, Issue:3

    Topics: Anesthesia; Animals; Avoidance Learning; Chlorides; Conditioning, Classical; Dose-Response Relations

1989
[Age-related aspects of intensive therapy of acute poisoning of chemical etiology].
    Terapevticheskii arkhiv, 1985, Volume: 57, Issue:5

    Topics: Acetates; Acetic Acid; Acute Disease; Adult; Age Factors; Critical Care; Ethylene Dichlorides; Hemop

1985
Skin lesions as a diagnostic aid in barbiturate poisoning.
    The New England journal of medicine, 1970, Aug-20, Volume: 283, Issue:8

    Topics: Barbiturates; Blister; Butyrates; Diagnosis, Differential; Female; Humans; Hypnotics and Sedatives;

1970
Comparison of haemoperfusion and haemodialysis in the therapy of barbiturate intoxication in dogs.
    Archiv fur Toxikologie, 1973, Volume: 31, Issue:2

    Topics: Animals; Barbiturates; Blood Platelets; Dogs; Leukocytes; Pentobarbital; Perfusion; Phenobarbital; P

1973
Activated charcoal preparations--relative antidotal efficacy.
    Clinical toxicology, 1974, Volume: 7, Issue:1

    Topics: Adsorption; Animals; Antidotes; Aspirin; Charcoal; Chlorpheniramine; Drug Stability; Lethal Dose 50;

1974
Hemodynamic effects of norepinephrine in severe hypnotic drug poisoning with arterial hypotension.
    Acta medica Scandinavica, 1972, Volume: 192, Issue:5

    Topics: Acid-Base Equilibrium; Adult; Aged; Amitriptyline; Blood Pressure; Carbamazepine; Cardiac Output; Ca

1972
Modifications of pyrrolizidine alkaloid intoxication resulting from altered hepatic microsomal enzymes.
    Toxicology and applied pharmacology, 1972, Volume: 23, Issue:3

    Topics: Animals; Chloramphenicol; Dose-Response Relationship, Drug; Drug Interactions; Injections, Subcutane

1972
Clinical evaluation of chronic, intermittent, and short term hemoperfusions in patients with chronic renal failure using semipermeable microcapsules (artificial cells) formed from membrane-coated activated charcoal.
    Transactions - American Society for Artificial Internal Organs, 1971, Volume: 17

    Topics: Adsorption; Aged; Blood Flow Velocity; Blood Platelets; Capsules; Charcoal; Creatinine; Embolism; Fe

1971
The action of activated charcoal on poisons in the digestive tract.
    Toxicology and applied pharmacology, 1970, Volume: 16, Issue:3

    Topics: Animals; Aspirin; Barbiturates; Charcoal; Chloroquine; Chlorpheniramine; Chlorpromazine; Digestive S

1970
Influence of sodium pentobarbital on mice poisoned by oxygen.
    Aerospace medicine, 1970, Volume: 41, Issue:9

    Topics: Animals; Hyperbaric Oxygenation; Lung; Male; Mice; Oxygen; Pentobarbital; Poisoning; Sodium; Water

1970
[Experimental determination of the effectiveness of hemodialysis of some medicinal substances and toxins].
    Biulleten' eksperimental'noi biologii i meditsiny, 1971, Volume: 71, Issue:4

    Topics: Alcoholic Intoxication; Amobarbital; Barbiturates; Ethanol; Humans; Methanol; Pentobarbital; Phenoba

1971
Hemodialysis in infants under 1 year of age for acute poisoning.
    American journal of diseases of children (1960), 1968, Volume: 116, Issue:6

    Topics: Blood Pressure; Female; Femoral Artery; Heparin; Humans; Infant; Kidneys, Artificial; Male; Pentobar

1968
Dialysis acidosis.
    Archives of internal medicine, 1969, Volume: 124, Issue:2

    Topics: Acid-Base Equilibrium; Acidosis; Adult; Bacteria; Benzalkonium Compounds; Bicarbonates; Carbon Dioxi

1969
Activated charcoal vs. "universal antidote" as an antidote for poisons.
    Toxicology and applied pharmacology, 1966, Volume: 8, Issue:3

    Topics: Animals; Antidotes; Charcoal; Insecticides; Male; Pentobarbital; Poisoning; Rats; Strychnine

1966
Evaluation of oral dilution as a first aid measure in poisoning.
    Journal of pharmaceutical sciences, 1966, Volume: 55, Issue:11

    Topics: Animals; Aspirin; Female; Intestinal Absorption; Pentobarbital; Poisoning; Quinine; Rats

1966