pentobarbital has been researched along with Paralysis in 23 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
Paralysis: A general term most often used to describe severe or complete loss of muscle strength due to motor system disease from the level of the cerebral cortex to the muscle fiber. This term may also occasionally refer to a loss of sensory function. (From Adams et al., Principles of Neurology, 6th ed, p45)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The zoxazolamine-paralysis times of mice treated with p-amino-2',4'-dichlorodiphenyl ether were longer than those of the control mice, while the same dose of zoxazolamine did not lead to paralysis in mice pretreated with BNF." | 3.72 | Effect of p-amino-diphenyl ethers on hepatic microsomal cytochrome P450. ( Jiang, H; Xuan, G, 2003) |
| " (1) MISO and related compounds inhibit drug-metabolising enzymes, as measured by pentobarbitone sleep-time and zoxazolamine paralysis-time." | 3.66 | Drug metabolism and chemosensitization. Nitroimidazoles as inhibitors of drug metabolism. ( Lee, FY; Twentyman, PR; Walton, MI; Workman, P, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (91.30) | 18.7374 |
| 1990's | 1 (4.35) | 18.2507 |
| 2000's | 1 (4.35) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jiang, H | 1 |
| Xuan, G | 1 |
| Morse, HN | 1 |
| Bachmann, K | 1 |
| Schwartz, J | 1 |
| Forney, R | 1 |
| Sherman, G | 1 |
| Jauregui, L | 1 |
| Ogeto, JO | 1 |
| Juma, FD | 1 |
| Muriuki, G | 1 |
| Workman, P | 1 |
| Twentyman, PR | 1 |
| Lee, FY | 1 |
| Walton, MI | 1 |
| Back, DJ | 1 |
| Purba, HS | 1 |
| Staiger, C | 1 |
| Orme, ML | 1 |
| Breckenridge, AM | 2 |
| Graham, JA | 1 |
| Menzel, DB | 1 |
| Miller, FJ | 1 |
| Illing, JW | 1 |
| Gardner, DE | 1 |
| Serlin, MJ | 1 |
| Challiner, M | 1 |
| Park, BK | 1 |
| Turcan, PA | 1 |
| Nathan, MA | 1 |
| Reis, DJ | 1 |
| Andersen, ME | 1 |
| Koppenhaver, RE | 1 |
| Jenkins, LJ | 1 |
| Connelly, CA | 1 |
| Otto-Smith, MR | 1 |
| Feldman, JL | 1 |
| McCullough, LS | 1 |
| Reier, CE | 1 |
| Delaunois, AL | 1 |
| Gardier, RW | 1 |
| Hamelberg, W | 1 |
| Allen, BD | 1 |
| Cummings, JF | 1 |
| De Lahunta, A | 1 |
| Kato, R | 4 |
| Takanaka, A | 3 |
| Rodieck, RW | 1 |
| Pettigrew, JD | 1 |
| Bishop, PO | 1 |
| Nikara, T | 1 |
| Burnham, SC | 1 |
| Martin, WE | 1 |
| Cheney, FW | 1 |
| Buxton, BH | 1 |
| Witschi, H | 1 |
| Plaa, GL | 1 |
| Sampson, SR | 1 |
| Hainsworth, R | 1 |
| Buck, SH | 1 |
| Lage, GL | 1 |
| Donelli, MG | 1 |
| Garattini, S | 1 |
| Onoda, K | 1 |
23 other studies available for pentobarbital and Paralysis
| Article | Year |
|---|---|
Effect of p-amino-diphenyl ethers on hepatic microsomal cytochrome P450.
Topics: Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System | 2003 |
Courtroom experiments by physicians.
Topics: Accidents, Traffic; Expert Testimony; Homicide; Humans; Jurisprudence; Paralysis; Pentobarbital | 1967 |
Selectivity of cholestyramine treatment on hepatic mixed function oxidase activity.
Topics: Adult; Amobarbital; Animals; Antipyrine; Bile Ducts; Body Temperature; Cholestyramine Resin; Female; | 1984 |
Practical therapeutics: some investigations of the toxic effects of the alkaloids extracted from Strychnos henningsii (Gilg) "muteta".
Topics: Alkaloids; Animals; Guinea Pigs; Humans; Mice; Neuromuscular Junction; Paralysis; Pentobarbital; Pla | 1984 |
Drug metabolism and chemosensitization. Nitroimidazoles as inhibitors of drug metabolism.
Topics: Aminopyrine; Animals; Chlorambucil; Female; Kidney Function Tests; Male; Metabolic Clearance Rate; M | 1983 |
Inhibition of drug metabolism by the antimalarial drugs chloroquine and primaquine in the rat.
Topics: Aminopyrine N-Demethylase; Animals; Antipyrine; Chloroquine; Kinetics; Male; Paralysis; Pentobarbita | 1983 |
Effect of ozone on drug-induced sleeping time in mice pretreated with mixed-function oxidase inducers and inhibitors.
Topics: Animals; Drug Interactions; Enzyme Induction; Female; Hexobarbital; Mice; Mice, Inbred C57BL; Mice, | 1982 |
Cimetidine potentiates the anticoagulant effect of warfarin by inhibition of drug metabolism.
Topics: Animals; Blood Coagulation; Cimetidine; Drug Synergism; Guanidines; Kinetics; Liver; Male; Paralysis | 1980 |
Hypoxemia, atelectasis, and the elevation of arterial pressure and heart rate in paralyzed artificially ventilated rat.
Topics: Animals; Blood; Blood Pressure; Carbon Dioxide; Ethyl Ethers; Female; Halothane; Heart Rate; Hydroge | 1975 |
Some neurotoxic properties of triethylene glycol dinitrate: a comparison with decamethonium.
Topics: Animals; Decamethonium Compounds; Drug Interactions; Ethylene Glycols; Lethal Dose 50; Male; Paralys | 1976 |
Blockade of NMDA receptor-channels by MK-801 alters breathing in adult rats.
Topics: Anesthesia; Animals; Dizocilpine Maleate; Electromyography; Male; Oxygen; Paralysis; Pentobarbital; | 1992 |
The effects of d-tubocurarine on spontaneous postganglionic sympathetic activity and histamine release.
Topics: Animals; Arteries; Blood Pressure; Catecholamines; Cats; Celiac Plexus; Ganglia, Autonomic; Heart Ra | 1970 |
The effects of prefrontal lobotomy on aggressive behavior in dogs.
Topics: Aggression; Anesthesia, General; Animals; Attention; Behavior, Animal; Cats; Dexamethasone; Dog Dise | 1974 |
Effect of starvation on the in vivo metabolism and effect of drugs in female and male rats.
Topics: Amides; Anesthesia; Animals; Barbiturates; Body Weight; Carisoprodol; Diphosphates; Female; Hexobarb | 1967 |
Residual eye movements in receptive-field studies of paralyzed cats.
Topics: Animals; Cats; Ethanolamines; Eye Movements; Gallamine Triethiodide; Paralysis; Pentobarbital; Sympa | 1967 |
The effects of various tidal volumes on gas exchange in pulmonary edema.
Topics: Anesthesia, Intravenous; Animals; Blood Gas Analysis; Cardiac Output; Dogs; Heart; Heart Rate; Oleic | 1972 |
Biochemical changes provoked in rat liver by cholestatic doses of -naphthylisothiocyanate.
Topics: Aminopyrine N-Demethylase; Animals; Bile Ducts; Carbon Isotopes; Carbon Tetrachloride; Cholestasis; | 1973 |
Responses of aortic body chemoreceptors of the cat to physiological stimuli.
Topics: Animals; Carbon Dioxide; Cats; Chemoreceptor Cells; Gallamine Triethiodide; Hydrogen-Ion Concentrati | 1972 |
Possible mechanism of the prevention of digitoxin toxicity by spironolactone in the mouse.
Topics: Animals; Digitoxin; Drug Antagonism; Enzyme Induction; Liver; Male; Mice; Paralysis; Pentobarbital; | 1971 |
Stimulatory effect of 6-aminochrysene and congeners on zoxazolamine metabolism.
Topics: Aniline Compounds; Animals; Anisoles; Carisoprodol; Drug Antagonism; Hydroxylation; In Vitro Techniq | 1971 |
Analysis and differentiation of the mechanism in the development of drug tolerance.
Topics: Analgesia; Anesthesia; Animals; Brain; Brain Chemistry; Drug Tolerance; Ethionine; Female; In Vitro | 1967 |
Metabolism of drugs in old rats. II. Metabolism in vivo and effect of drugs in old rats.
Topics: Aging; Anesthesia; Animals; Carisoprodol; Female; Hexobarbital; Injections, Intraperitoneal; Insecti | 1968 |
Individual difference in the effect of drugs in relation to the tissue concentration of drugs.
Topics: Anesthesia; Animals; Brain; Female; Paralysis; Pentobarbital; Rats; Zoxazolamine | 1969 |