pentobarbital has been researched along with Myocardial Ischemia in 8 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neither halothane nor sevoflurane protected the heart against the effects of acute and severe regional myocardial ischemia." | 7.70 | Anesthetic modulation of myocardial ischemia and reperfusion injury in pigs: comparison between halothane and sevoflurane. ( Coetzee, A; Coetzee, J; Conradie, S, 1999) |
| "The acute administration of acetaminophen to isolated, perfused guinea pig hearts appears to have cardioprotective effects against the injury/mechanical dysfunction caused by global, low-flow, myocardial ischemia and reperfusion." | 3.71 | Antioxidant properties of acetaminophen and cardioprotection. ( Goldberg, E; Merrill, GF, 2001) |
| "Neither halothane nor sevoflurane protected the heart against the effects of acute and severe regional myocardial ischemia." | 3.70 | Anesthetic modulation of myocardial ischemia and reperfusion injury in pigs: comparison between halothane and sevoflurane. ( Coetzee, A; Coetzee, J; Conradie, S, 1999) |
| "Lopinavir was administered as a co-formulated drug of lopinavir and ritonavir." | 1.39 | Optimized administration regimen of lopinavir for a myocardial ischaemia reperfusion study in Sprague-Dawley rats. ( Belohlavek, M; Bukatina, AE; Gades, NM; Jiamsripong, P; Katayama, M; Lombari, TR; McMahon, EM, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (62.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, J | 1 |
| Li, H | 1 |
| Xun, L | 1 |
| Wang, L | 1 |
| Zhao, Q | 1 |
| Katayama, M | 1 |
| Jiamsripong, P | 1 |
| Bukatina, AE | 1 |
| Lombari, TR | 1 |
| McMahon, EM | 1 |
| Gades, NM | 1 |
| Belohlavek, M | 1 |
| Haessler, R | 1 |
| Kuzume, K | 1 |
| Chien, GL | 1 |
| Wolff, RA | 1 |
| Davis, RF | 1 |
| Van Winkle, DM | 1 |
| Oguchi, T | 1 |
| Kashimoto, S | 1 |
| Yamaguchi, T | 1 |
| Nakamura, T | 1 |
| Kumazawa, T | 1 |
| Morita, Y | 1 |
| Murakami, T | 1 |
| Iwase, T | 1 |
| Nagai, K | 1 |
| Nawada, R | 1 |
| Kouchi, I | 1 |
| Akao, M | 1 |
| Sasayama, S | 1 |
| Schwartz, LM | 1 |
| Jennings, RB | 1 |
| Reimer, KA | 1 |
| Conradie, S | 1 |
| Coetzee, A | 1 |
| Coetzee, J | 1 |
| Merrill, GF | 1 |
| Goldberg, E | 1 |
8 other studies available for pentobarbital and Myocardial Ischemia
| Article | Year |
|---|---|
Hyperlipidemia attenuates the mobilization of endothelial progenitor cells induced by acute myocardial ischemia via VEGF/eNOS/NO/MMP-9 pathway.
Topics: Animals; Collagen; Emulsions; Endothelial Progenitor Cells; Hyperlipidemias; Matrix Metalloproteinas | 2022 |
Optimized administration regimen of lopinavir for a myocardial ischaemia reperfusion study in Sprague-Dawley rats.
Topics: Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Combinations; | 2013 |
Anaesthetics alter the magnitude of infarct limitation by ischaemic preconditioning.
Topics: Anesthetics; Animals; Blood Glucose; Constriction; Coronary Vessels; Heart; Isoflurane; Ketamine; My | 1994 |
Is pentobarbital appropriate for basal anesthesia in the working rat heart model?
Topics: Administration, Inhalation; Anesthesia; Animals; Ethers; Heart; Hemodynamics; Injections, Intraperit | 1993 |
K(ATP) channels contribute to the cardioprotection of preconditioning independent of anaesthetics in rabbit hearts.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Anesthetics; Animals; Cardiotonic Agents; Female; Hemodyn | 1997 |
Premedication with the opioid analgesic butorphanol raises the threshold for ischemic preconditioning in dogs.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Butorphanol; Cardiotonic Agents; Coronary Circula | 1997 |
Anesthetic modulation of myocardial ischemia and reperfusion injury in pigs: comparison between halothane and sevoflurane.
Topics: Adjuvants, Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Fentanyl; Halotha | 1999 |
Antioxidant properties of acetaminophen and cardioprotection.
Topics: Acetaminophen; Action Potentials; Analgesics, Non-Narcotic; Animals; Antioxidants; Cardiotonic Agent | 2001 |