pentobarbital has been researched along with Morphine Abuse in 25 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Under pentobarbital anesthesia, precipitated shakes and ice water-induced wet shakes were inhibited by clonidine and norepinephrine." | 3.65 | Effects of clonidine on morphine withdrawal signs in the rat. ( Loh, HH; Tseng, LF; Wei, ET, 1975) |
| "Here we report on the assessment of withdrawal symptoms in morphine-dependent rats which received continuous naloxone administration combined with barbiturate anaesthesia." | 1.30 | Forced opiate withdrawal under anaesthesia augments and prolongs the occurrence of withdrawal signs in rats. ( Holsboer, F; Kirschke, C; Spanagel, R; Tretter, F, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (92.00) | 18.7374 |
| 1990's | 1 (4.00) | 18.2507 |
| 2000's | 1 (4.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kotlinska, J | 1 |
| Wichmann, J | 1 |
| Rafalski, P | 1 |
| Talarek, S | 1 |
| Dylag, T | 1 |
| Silberring, J | 1 |
| HILL, HE | 3 |
| HAERTZEN, CA | 4 |
| WOLBACH, AB | 2 |
| MINER, EJ | 2 |
| BELLEVILLE, RE | 1 |
| HAMBURGER, E | 1 |
| Wei, ET | 2 |
| Ross, FE | 1 |
| Spanagel, R | 1 |
| Kirschke, C | 1 |
| Tretter, F | 1 |
| Holsboer, F | 1 |
| Rosenfeld, GC | 1 |
| Burks, TF | 1 |
| Contreras, E | 1 |
| Tamayo, L | 1 |
| Quijada, L | 1 |
| Jones, MA | 1 |
| Spratto, GR | 1 |
| Pack, RL | 1 |
| Ferko, AP | 1 |
| Peterson, GR | 1 |
| Covault, HP | 1 |
| Hostetler, RM | 1 |
| Murano, T | 1 |
| Senda, H | 1 |
| Yamamoto, H | 1 |
| Yano, I | 1 |
| Geller, EB | 1 |
| Durlofsky, L | 1 |
| Cowan, A | 1 |
| Harakal, C | 1 |
| Adler, MW | 1 |
| Grant, I | 1 |
| Adams, KM | 1 |
| Carlin, AS | 1 |
| Rennick, PM | 1 |
| Judd, LL | 1 |
| Schooff, K | 1 |
| Reed, R | 1 |
| Tseng, LF | 1 |
| Loh, HH | 1 |
| Banerjee, U | 1 |
| Cicero, TJ | 1 |
| Meyer, ER | 1 |
| Bell, RD | 1 |
| Zahn, MA | 1 |
| Ball, JC | 1 |
| Nurimoto, S | 1 |
| Kamei, C | 1 |
| Shimomura, K | 1 |
| Ueki, S | 1 |
| Fraser, HF | 1 |
| Deneau, G | 1 |
| Yanagita, T | 1 |
| Seevers, MH | 1 |
| Gray, GR | 1 |
| Smith, DE | 1 |
| Wesson, DR | 1 |
| Sheppard, CW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Difference in Pharmacodynamic and Pharmacokinetic Profiles Between Tentin and Magisterial Dexamfetamine in Adults With Attention Deficit Hyperactivity Disorder, a Double Blinded Randomised Crossover-controlled Trial[NCT05621174] | 26 participants (Anticipated) | Interventional | 2023-04-14 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pentobarbital and Morphine Abuse
| Article | Year |
|---|---|
Certain theoretical and practical considerations involved in evaluating the overall abuse potential of opiate agonists and antagonists.
Topics: Animals; Chlorpromazine; Codeine; Cyclazocine; Drug Combinations; Drug Evaluation; Drug Evaluation, | 1973 |
24 other studies available for pentobarbital and Morphine Abuse
| Article | Year |
|---|---|
Non-peptidergic OP4 receptor agonist inhibits morphine antinociception but does not influence morphine dependence.
Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Inte | 2003 |
THE ADDICTION RESEARCH CENTER INVENTORY: STANDARDIZATION OF SCALES WHICH EVALUATE SUBJECTIVE EFFECTS OF MORPHINE, AMPHETAMINE, PENTOBARBITAL, ALCOHOL, LSD-25, PYRAHEXYL AND CHLORPROMAZINE.
Topics: Alcohols; Amphetamine; Amphetamines; Antidepressive Agents; Behavior, Addictive; Benzopyrans; Chlorp | 1963 |
THE ADDICTION RESEARCH CENTER INVENTORY: APPENDIX. I. ITEMS COMPRISING EMPIRICAL SCALES FOR SEVEN DRUGS. II. ITEMS WHICH DO NOT DIFFERENTIATE PLACEBO FROM ANY DRUG CONDITION.
Topics: Alcohols; Amphetamine; Amphetamines; Antidepressive Agents; Appendix; Behavior, Addictive; Chlorprom | 1963 |
DEVELOPMENT OF THE ADDICTION RESEARCH CENTER INVENTORY (ARCI): SELECTION OF ITEMS THAT ARE SENSITIVE TO THE EFFECTS OF VARIOUS DRUGS.
Topics: Amphetamine; Amphetamines; Behavior, Addictive; Chlorpromazine; Humans; Lysergic Acid Diethylamide; | 1963 |
BARBITURATE USE IN NARCOTIC ADDICTS.
Topics: Barbiturates; Codeine; Drug Tolerance; Ethchlorvynol; Glutethimide; Heroin; Hydromorphone; Hypnotics | 1964 |
Pharmacological aspects of shaking behavior produced by TRH, AG-3-5, and morphine withdrawal.
Topics: Animals; Cold Temperature; Escape Reaction; Humans; Morphine Dependence; Naloxone; Pentobarbital; Py | 1981 |
Strength of drug habits: for heroin, morphine, methadone, alcohol, barbiturates, pentobarbital, benzedrine, cocaine, and marijuana.
Topics: Adult; Alcoholism; Amphetamines; Barbiturates; Cannabis; Cocaine; Heroin Dependence; Humans; Male; M | 1980 |
Forced opiate withdrawal under anaesthesia augments and prolongs the occurrence of withdrawal signs in rats.
Topics: Anesthesia, General; Animals; Male; Morphine Dependence; Naloxone; Narcotic Antagonists; Neurologic | 1998 |
Single-dose tolerance to morphine hypothermia in the rat: differentiation of acute from long-term tolerance.
Topics: Animals; Body Temperature; Depression, Chemical; Drug Interactions; Drug Tolerance; Humans; Injectio | 1977 |
Partial inhibition of the abstinence syndrome in morphine tolerant-dependent mice following pharmacological denervation.
Topics: 5-Hydroxytryptophan; Animals; Atropine; Behavior, Animal; Denervation; Drug Tolerance; Humans; Methy | 1978 |
Ethanol suppression of naloxone-induced withdrawal in morphine-dependent rats.
Topics: Animals; Brain; Ethanol; Humans; Male; Morphine; Morphine Dependence; Naloxone; Pentobarbital; Rats; | 1977 |
The effects of ethanol and pentobarbital on the naloxone precipitated escape response in morphine dependent mice.
Topics: Animals; Drug Interactions; Escape Reaction; Ethanol; Humans; Male; Mice; Morphine Dependence; Nalox | 1977 |
Acute inhibition of microsomal drug metabolism by propoxyphene in narcotic tolerant/dependent mice.
Topics: Animals; Dextropropoxyphene; Drug Tolerance; Humans; Male; Methadone; Mice; Microsomes, Liver; Mixed | 1978 |
Studies on the physical dependence potential of analgesics.
Topics: Adrenal Cortex; Animals; Chlorpromazine; Humans; Levallorphan; Male; Mice; Mitochondria; Morphine; M | 1978 |
The effect of pentobarbital on the antinociceptive action of morphine in morphine-tolerant and non-tolerant rats.
Topics: Animals; Drug Tolerance; Humans; Male; Morphine; Morphine Dependence; Pain; Pentobarbital; Rats; Sen | 1979 |
Organic impairment in polydrug users: risk factors.
Topics: Adult; Age Factors; Brain; Educational Status; Female; Follow-Up Studies; Heroin Dependence; Humans; | 1978 |
Effects of clonidine on morphine withdrawal signs in the rat.
Topics: Anesthesia; Animals; Body Temperature; Cerebral Ventricles; Clonidine; Escape Reaction; Exophthalmos | 1975 |
Conditioned avoidance behavior in pretrained rats intermittently treated with addictive drugs.
Topics: Amphetamine; Animals; Avoidance Learning; Body Weight; Conditioning, Operant; Dose-Response Relation | 1975 |
Effects of phenoxybenzamine on the narcotic withdrawal syndrome in the rat.
Topics: Adrenergic beta-Antagonists; Animals; Behavior, Animal; Body Weight; Chlorpromazine; Depression, Che | 1974 |
Patterns and causes of drug addiction among Puerto Rican females.
Topics: Adolescent; Adult; Cannabis; Child; Criminal Psychology; Drug Prescriptions; Employment; Female; Her | 1974 |
A simple method for evaluating physical dependence liability in rats.
Topics: Aminopyrine; Animals; Azepines; Body Weight; Codeine; Cyproheptadine; Dextropropoxyphene; Humans; Ma | 1973 |
Significance of withdrawal jumping response in predicting physical dependence in mice.
Topics: Amitriptyline; Animals; Atropine; Cannabis; Chlordiazepoxide; Chlorpromazine; Diazepam; Humans; Imip | 1973 |
Self-administration of psychoactive substances by the monkey.
Topics: Animals; Behavior, Animal; Caffeine; Catheterization; Chlorpromazine; Cocaine; Codeine; Dextroamphet | 1969 |
Outpatient barbiturate withdrawal using phenobarbital.
Topics: Administration, Oral; Adolescent; Adult; Ambulatory Care; Amobarbital; Barbiturates; Community Healt | 1972 |