pentobarbital has been researched along with Magnesium Deficiency in 3 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
Magnesium Deficiency: A nutritional condition produced by a deficiency of magnesium in the diet, characterized by anorexia, nausea, vomiting, lethargy, and weakness. Symptoms are paresthesias, muscle cramps, irritability, decreased attention span, and mental confusion, possibly requiring months to appear. Deficiency of body magnesium can exist even when serum values are normal. In addition, magnesium deficiency may be organ-selective, since certain tissues become deficient before others. (Harrison's Principles of Internal Medicine, 12th ed, p1936)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Loreclezole was also shown to inhibit 'low Ca2+' and 'low Mg2+' epileptogenesis at similar concentrations to those active on inhibition." | 1.28 | In vitro studies on the broad spectrum anticonvulsant loreclezole in the hippocampus. ( Ashton, D; Willems, R, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Altura, BM | 1 |
| Altura, BT | 1 |
| Becking, GC | 1 |
| Ashton, D | 1 |
| Willems, R | 1 |
1 review available for pentobarbital and Magnesium Deficiency
| Article | Year |
|---|---|
Microcirculatory actions and uses of naturally-occurring (magnesium) and novel synthetic calcium channel blockers.
Topics: Anesthesia; Animals; Arterioles; Blood Pressure; Calcium; Calcium Channel Blockers; Cell Membrane Pe | 1984 |
2 other studies available for pentobarbital and Magnesium Deficiency
| Article | Year |
|---|---|
Hepatic drug metabolism in iron-, magnesium- and potassium-deficient rats.
Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Carboxylic Ester Hydrolases; Cytochrome P-4 | 1976 |
In vitro studies on the broad spectrum anticonvulsant loreclezole in the hippocampus.
Topics: Animals; Anticonvulsants; Calcium; Electric Stimulation; Epilepsy; Etomidate; gamma-Aminobutyric Aci | 1992 |