pentobarbital has been researched along with Liver Diseases in 21 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
Liver Diseases: Pathological processes of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to determine the relative roles of viral-induced interferon (IFN) and viral infection of the liver in mouse cytomegalovirus (MCMV)-induced depression of cytochrome P-450 (cyt P-450) levels and enhancement of pentobarbital-induced sleeping time (PEN-ST)." | 7.67 | Increased susceptibility to pentobarbital following mouse cytomegalovirus infection: relative roles of viral-induced interferon and viral infection of the liver. ( Catignani, JC; Ménache, MG; Selgrade, MK, 1989) |
| "The purpose of this study was to determine the relative roles of viral-induced interferon (IFN) and viral infection of the liver in mouse cytomegalovirus (MCMV)-induced depression of cytochrome P-450 (cyt P-450) levels and enhancement of pentobarbital-induced sleeping time (PEN-ST)." | 3.67 | Increased susceptibility to pentobarbital following mouse cytomegalovirus infection: relative roles of viral-induced interferon and viral infection of the liver. ( Catignani, JC; Ménache, MG; Selgrade, MK, 1989) |
| " These permit the elaboration of dose-response lines for the substances in question, the calculation of median effective doses and the statistical analysis of differences in liver-damaging potency." | 1.26 | Quantitative aspects in the assessment of liver injury. ( Plaa, GL, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (90.48) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BALAZS, T | 1 |
| GRICE, HC | 1 |
| WALLNER, S | 1 |
| Knodell, RG | 1 |
| Farleigh, RM | 1 |
| Steele, NM | 1 |
| Bond, JH | 1 |
| Vanderhoof, JA | 1 |
| Tuma, DJ | 1 |
| Antonson, DL | 1 |
| Sorrell, MF | 1 |
| de Ferreyra, EC | 1 |
| de Fenos, OM | 2 |
| Castro, JA | 3 |
| Gilani, AH | 1 |
| Janbaz, KH | 1 |
| Chiba, T | 1 |
| Horiuchi, M | 1 |
| Akashi, Y | 1 |
| Singh, D | 1 |
| Vijayvargiya, R | 1 |
| Kakrani, AL | 1 |
| Chakraborty, J | 1 |
| Donatelli, L | 1 |
| Marmo, E | 1 |
| Ferreyra, EC | 1 |
| de Castro, CR | 1 |
| Diaz Gómez, MI | 1 |
| Gram, TE | 1 |
| Reagan, RL | 1 |
| Guarino, AM | 1 |
| González Macías, J | 1 |
| De Castro del Pozo, S | 1 |
| Plaa, GL | 2 |
| Zhang, ZL | 1 |
| Wen, QZ | 1 |
| Liu, CX | 1 |
| Catignani, JC | 1 |
| Ménache, MG | 1 |
| Selgrade, MK | 1 |
| Van Puyvelde, L | 1 |
| Kayonga, A | 1 |
| Brioen, P | 1 |
| Costa, J | 1 |
| Ndimubakunzi, A | 1 |
| De Kimpe, N | 1 |
| Schamp, N | 1 |
| Takeda, T | 1 |
| Enomoto, M | 1 |
| Makita, T | 1 |
| Black, M | 1 |
| Hollwich, F | 1 |
| Dieckhues, B | 1 |
| Cignoli, EV | 1 |
| Becker, BA | 1 |
2 reviews available for pentobarbital and Liver Diseases
| Article | Year |
|---|---|
[Current status of hepatic and biliary drug therapy. Part I].
Topics: Biliary Tract Diseases; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chol | 1976 |
Liver disease and drug therapy.
Topics: Amobarbital; Azathioprine; Half-Life; Humans; Lidocaine; Liver Cirrhosis; Liver Diseases; Metabolic | 1974 |
19 other studies available for pentobarbital and Liver Diseases
| Article | Year |
|---|---|
The relationship between liver necrosis and pentobarbital sleeping time in rats.
Topics: Animals; Liver Diseases; Pentobarbital; Rats; Sleep | 1963 |
[EXPERIENCES WITH THE SEDATIVE PENTOBARBITAL CALCIUM (REPOCAL)].
Topics: Calcium, Dietary; Humans; Hypnotics and Sedatives; Liver Diseases; Pentobarbital; Sleep Wake Disorde | 1963 |
Effects of liver congestion on hepatic drug metabolism in the rat.
Topics: Animals; Blood Proteins; In Vitro Techniques; Kinetics; Liver; Liver Diseases; Male; Microsomes, Liv | 1982 |
Effect of antibiotics in the prevention of jejunoileal bypass-induced liver dysfunction.
Topics: Animals; Cytochrome P-450 Enzyme System; Ileum; Jejunum; Liver Diseases; Male; Microsomes, Liver; Mi | 1982 |
Effect of different chemicals on thioacetamine-induced liver necrosis.
Topics: Acetamides; Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Liver; | 1980 |
Preventive and curative effects of Artemisia absinthium on acetaminophen and CCl4-induced hepatotoxicity.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Che | 1995 |
[Effect of thiol compounds on experimental liver damage (III). Effect of tiopronin (2-mercaptopropionylglycine) and glutathione on drug metabolizing activity (author's transl)].
Topics: Amino Acids, Sulfur; Aminopyrine; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Chemical | 1979 |
Activity and inducibility of hepatic microsomal enzymes in liver diseases.
Topics: Adolescent; Adult; Aged; Enzyme Induction; Half-Life; Humans; Liver Diseases; Microsomes, Liver; Mid | 1977 |
Alcohol and its metabolic interactions with other drugs.
Topics: Aniline Hydroxylase; Animals; Drug Interactions; Endoplasmic Reticulum; Ethanol; Humans; Hydrolases; | 1978 |
Studies on the role of protein syntheis in cell injury by toxic agents: I. Effect of cycloheximide administration on several factors modulating carbon tetrachloride-induced liver necrosis.
Topics: Animals; Body Temperature; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cycloheximi | 1977 |
[Metabolism of phenylbutazone in the liver (author's transl)].
Topics: Alcoholism; Cholestasis; Diabetes Mellitus; Enzyme Induction; Epilepsy; Ethanol; Half-Life; Hepatiti | 1976 |
Quantitative aspects in the assessment of liver injury.
Topics: 1-Propanol; Alanine Transaminase; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Che | 1976 |
Hepatoprotective effects of astraglus root.
Topics: Alanine Transaminase; Animals; Astragalus propinquus; Drugs, Chinese Herbal; Female; Liver; Liver Di | 1990 |
Increased susceptibility to pentobarbital following mouse cytomegalovirus infection: relative roles of viral-induced interferon and viral infection of the liver.
Topics: Aging; Animals; Antibodies; Cytochrome P-450 Enzyme System; Cytomegalovirus; Cytomegalovirus Infecti | 1989 |
The hepatoprotective principle of Hypoestes triflora leaves.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzoates; Benzoic Acid; Carbon Tetrachl | 1989 |
Gross and microscopic characteristics of liver lesions induced by direct injection of pentobarbital sodium into rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; | 1987 |
[Ocular light perception and metabolic activity of the liver (author's transl)].
Topics: Animals; Bilirubin; Blindness; Cataract; Cataract Extraction; Chemical and Drug Induced Liver Injury | 1974 |
Effect of inhibitors of drug metabolizing enzymes on carbon tetrachloride hepatotoxicity.
Topics: Aminopyrine; Animals; Biotransformation; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemi | 1971 |
Quantitative and temporal delineation of various parameters of liver dysfunction due to alpha-naphthylisothiocyanate.
Topics: Animals; Bile; Bilirubin; Blood; Chromatography, Paper; Hyperbilirubinemia; Liver; Liver Diseases; M | 1965 |