pentobarbital has been researched along with Learning Disabilities in 4 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
Learning Disabilities: Conditions characterized by a significant discrepancy between an individual's perceived level of intellect and their ability to acquire new language and other cognitive skills. These may result from organic or psychological conditions. Relatively common subtypes include DYSLEXIA, DYSCALCULIA, and DYSGRAPHIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gravid Sprague-Dawley-derived rats were injected SC twice daily with either 20 or 40 mg/kg pentobarbital sodium (PT), sodium phenobarbital (PH), or the same volume of the saline vehicle on days 9-21 of pregnancy." | 3.67 | Maternal barbiturate administration and offspring response to shock. ( Chao, S; Grace, R; Mackler, B; Martin, DC; Martin, JC; Shores, P, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, W | 1 |
| Tan, T | 1 |
| Tu, M | 1 |
| He, W | 1 |
| Dong, Z | 1 |
| Han, H | 1 |
| Tong, LM | 1 |
| Yoon, SY | 1 |
| Andrews-Zwilling, Y | 1 |
| Yang, A | 1 |
| Lin, V | 1 |
| Lei, H | 1 |
| Huang, Y | 1 |
| Otsuka, Y | 1 |
| Watanabe, S | 1 |
| Martin, JC | 1 |
| Martin, DC | 1 |
| Mackler, B | 1 |
| Grace, R | 1 |
| Shores, P | 1 |
| Chao, S | 1 |
4 other studies available for pentobarbital and Learning Disabilities
| Article | Year |
|---|---|
Acute pentobarbital treatment impairs spatial learning and memory and hippocampal long-term potentiation in rats.
Topics: Animals; Bicuculline; Biophysics; Dose-Response Relationship, Drug; Electric Stimulation; Escape Rea | 2015 |
Enhancing GABA Signaling during Middle Adulthood Prevents Age-Dependent GABAergic Interneuron Decline and Learning and Memory Deficits in ApoE4 Mice.
Topics: Aging; Animals; Apolipoprotein E4; Female; GABA Agonists; gamma-Aminobutyric Acid; Gene Knock-In Tec | 2016 |
Effects of hippocampal lesions on conditional discriminations in rats.
Topics: Animals; Conditioning, Psychological; Cues; Denervation; Discrimination Learning; Disease Models, An | 2006 |
Maternal barbiturate administration and offspring response to shock.
Topics: Animals; Avoidance Learning; Body Weight; Brain; Conditioning, Operant; Electroshock; Female; Humans | 1985 |