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pentobarbital and Lactic Acidosis

pentobarbital has been researched along with Lactic Acidosis in 3 studies

Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.

Research Excerpts

ExcerptRelevanceReference
"We present a rare case of pentobarbital infusion causing propylene glycol-induced lactic acidosis, during refractory status epilepticus treatment in a 66-year-old man without seizure history."7.88Pentobarbital-induced lactic acidosis following status epilepticus barbiturate coma. ( Ghazala, S; Golden, TR; Solnicky, V; Wadeea, R, 2018)
"To report a case of probable propylene glycol (PG) toxicity in a patient receiving continuous infusion of pentobarbital for refractory status epilepticus."7.74Propylene glycol-induced lactic acidosis in a patient receiving continuous infusion pentobarbital. ( Forni, A; Miller, MA; Yogaratnam, D, 2008)
" The effects of two anaesthetics, sodium pentobarbital and urethane, and the effects of anaesthesia-associated hypothermia on acid-base status and blood gases were studied in rats without assisted ventilation."7.68Differential effects of hypothermia upon blood acid-base state and blood gases in sodium pentobarbital and urethane anaesthetised rats. ( Alfaro, V; Palacios, L, 1992)
"We present a rare case of pentobarbital infusion causing propylene glycol-induced lactic acidosis, during refractory status epilepticus treatment in a 66-year-old man without seizure history."3.88Pentobarbital-induced lactic acidosis following status epilepticus barbiturate coma. ( Ghazala, S; Golden, TR; Solnicky, V; Wadeea, R, 2018)
"To report a case of probable propylene glycol (PG) toxicity in a patient receiving continuous infusion of pentobarbital for refractory status epilepticus."3.74Propylene glycol-induced lactic acidosis in a patient receiving continuous infusion pentobarbital. ( Forni, A; Miller, MA; Yogaratnam, D, 2008)
" The effects of two anaesthetics, sodium pentobarbital and urethane, and the effects of anaesthesia-associated hypothermia on acid-base status and blood gases were studied in rats without assisted ventilation."3.68Differential effects of hypothermia upon blood acid-base state and blood gases in sodium pentobarbital and urethane anaesthetised rats. ( Alfaro, V; Palacios, L, 1992)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Golden, TR1
Solnicky, V1
Wadeea, R1
Ghazala, S1
Miller, MA1
Forni, A1
Yogaratnam, D1
Alfaro, V1
Palacios, L1

Other Studies

3 other studies available for pentobarbital and Lactic Acidosis

ArticleYear
Pentobarbital-induced lactic acidosis following status epilepticus barbiturate coma.
    BMJ case reports, 2018, Feb-22, Volume: 2018

    Topics: Acidosis, Lactic; Aged; Coma; Humans; Hypnotics and Sedatives; Male; Pentobarbital; Status Epileptic

2018
Propylene glycol-induced lactic acidosis in a patient receiving continuous infusion pentobarbital.
    The Annals of pharmacotherapy, 2008, Volume: 42, Issue:10

    Topics: Acidosis, Lactic; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Middle Aged; Pent

2008
Differential effects of hypothermia upon blood acid-base state and blood gases in sodium pentobarbital and urethane anaesthetised rats.
    General pharmacology, 1992, Volume: 23, Issue:4

    Topics: Acid-Base Equilibrium; Acidosis, Lactic; Anesthesia; Animals; Blood Gas Analysis; Body Temperature;

1992