pentobarbital has been researched along with Ischemia in 27 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study was performed to compare haemodynamic variables at baseline and the incidence of ventricular fibrillation during the early phase of ischaemia in swine during pentobarbital or medetomidine-ketamine-fentanyl anaesthesia." | 7.72 | Pentobarbital versus medetomidine-ketamine-fentanyl anaesthesia: effects on haemodynamics and the incidence of ischaemia-induced ventricular fibrillation in swine. ( Grund, F; Ilebekk, A; Kirkebøen, KA; Sjaastad, I; Tjomsland, O, 2004) |
| "Hemodynamic and metabolic consequences of a 90-minute period of liver ischemia followed by 120 minutes of reperfusion were studied in rats that were awake during most of the experiment and in rats anesthetized with either pentobarbital (40 mg/kg body weight) or chloralose (30 mg/kg X hour) during the complete length of the experiment." | 7.68 | Influence of pentobarbital and chloralose on metabolic and hemodynamic changes in liver ischemia. ( Biber, B; Hasselgren, PO; Nordström, G; Winsö, O, 1990) |
| "The present study was performed to compare haemodynamic variables at baseline and the incidence of ventricular fibrillation during the early phase of ischaemia in swine during pentobarbital or medetomidine-ketamine-fentanyl anaesthesia." | 3.72 | Pentobarbital versus medetomidine-ketamine-fentanyl anaesthesia: effects on haemodynamics and the incidence of ischaemia-induced ventricular fibrillation in swine. ( Grund, F; Ilebekk, A; Kirkebøen, KA; Sjaastad, I; Tjomsland, O, 2004) |
| "Clomipramine which has a stimulating effect on oxygen metabolism should be kept in reserve for the chronic phase of prolonged coma." | 1.26 | [Prolonged traumatic and vascular coma: prognostic and therapeutic indications based on hemodynamic and metabolic studies]. ( Baldy-Moulinier, M; Escuret, E; Frèrebeau, P; Passouant, P; Roquefeuil, B, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (81.48) | 18.7374 |
| 1990's | 3 (11.11) | 18.2507 |
| 2000's | 2 (7.41) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| JILEK, L | 1 |
| TROJAN, S | 1 |
| Grund, F | 1 |
| Tjomsland, O | 1 |
| Sjaastad, I | 1 |
| Ilebekk, A | 1 |
| Kirkebøen, KA | 1 |
| Gradl, G | 1 |
| Gaida, S | 1 |
| Finke, B | 1 |
| Lindenblatt, N | 1 |
| Gierer, P | 1 |
| Menger, MD | 1 |
| Mittlmeier, T | 1 |
| Vollmar, B | 1 |
| Osborn, JL | 1 |
| Kopp, UC | 1 |
| DiBona, GF | 1 |
| Finn, WF | 1 |
| Lukácová, N | 1 |
| Chavko, M | 1 |
| Halát, G | 1 |
| Thorniley, MS | 1 |
| Lane, N | 1 |
| Simpkin, S | 1 |
| Fuller, B | 1 |
| Jenabzadeh, MZ | 1 |
| Green, CJ | 1 |
| Micic, D | 1 |
| Klatzo, I | 1 |
| Spatz, M | 1 |
| Anderson, RE | 1 |
| Sundt, TM | 1 |
| Yasuda, H | 1 |
| Shuto, S | 1 |
| Tsumagari, T | 1 |
| Nakajima, A | 1 |
| Moseley, JI | 1 |
| Laurent, JP | 1 |
| Molinari, GF | 1 |
| Michenfelder, JD | 1 |
| Milde, JH | 1 |
| Barton, RN | 1 |
| Baldy-Moulinier, M | 1 |
| Roquefeuil, B | 1 |
| Escuret, E | 1 |
| Frèrebeau, P | 1 |
| Passouant, P | 1 |
| Green, JF | 1 |
| Nordström, G | 1 |
| Winsö, O | 1 |
| Biber, B | 1 |
| Hasselgren, PO | 1 |
| French, TJ | 1 |
| Goode, AW | 1 |
| Sugden, MC | 1 |
| Hoff, J | 1 |
| Smith, A | 1 |
| Nielsen, S | 1 |
| Larson, P | 1 |
| Creasy, RK | 1 |
| Kahanpää, KV | 1 |
| De Swiet, M | 1 |
| Vatner, SF | 1 |
| Monroe, RG | 1 |
| McRitchie, RJ | 1 |
| Nordzell, B | 1 |
| Spieckermann, PG | 1 |
| Brückner, J | 1 |
| Kübler, W | 1 |
| Lohr, B | 1 |
| Bretschneider, HJ | 1 |
| Matsushita, A | 1 |
| Smith, CM | 1 |
| Döring, HJ | 1 |
| Olbrisch, RR | 1 |
| Randall, HM | 1 |
| Toth, LA | 1 |
| Kim, M | 1 |
| Gauert, WB | 1 |
| Schloerb, PR | 1 |
| Schmahl, FW | 1 |
| Betz, E | 1 |
| Talke, H | 1 |
| Hohorst, HJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Triangulation, Eye of the Needle and Stone Direct Targeting Percutaneous Renal Access Techniques of Nephrolithotomy : Randomized Controlled Trial[NCT04846699] | 150 participants (Anticipated) | Observational | 2021-04-20 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pentobarbital and Ischemia
| Article | Year |
|---|---|
Cerebral protection by anaesthetics during ischaemia: (a review).
Topics: Anesthetics; Animals; Barbiturates; Brain; Cerebrovascular Circulation; Dogs; Halothane; Haplorhini; | 1975 |
26 other studies available for pentobarbital and Ischemia
| Article | Year |
|---|---|
[Influences on resistance of the body against oligemia and ischemia of the CNS during the course of ontogenesis].
Topics: Aging; Central Nervous System; Chlorpromazine; Hyperglycemia; Hypoxia; Ischemia; Pentobarbital | 1963 |
Pentobarbital versus medetomidine-ketamine-fentanyl anaesthesia: effects on haemodynamics and the incidence of ischaemia-induced ventricular fibrillation in swine.
Topics: Anesthesia; Anesthetics; Animals; Constriction; Coronary Vessels; Female; Fentanyl; Hemodynamics; Is | 2004 |
Supernatant of traumatized muscle induces inflammation and pain, but not microcirculatory perfusion failure and apoptotic cell death.
Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Death; Edema; Hemodynamics; In Situ | 2005 |
Ischemic acute renal failure: newer implications of stopped pipes.
Topics: Acute Kidney Injury; Animals; Humans; Ischemia; Kidney; Kidney Tubules, Proximal; Pentobarbital; Rat | 1981 |
Nephron heterogeneity in polyuric acute renal failure.
Topics: Acute Kidney Injury; Animals; Ischemia; Kidney; Kidney Tubules, Proximal; Male; Pentobarbital; Polyu | 1981 |
Effect of stobadine on lipid peroxidation and phospholipids in rabbit spinal cord after ischaemia.
Topics: Animals; Antioxidants; Carbolines; Chromatography, Thin Layer; In Vitro Techniques; Iron; Ischemia; | 1993 |
Monitoring of mitochondrial NADH levels by surface fluorimetry as an indication of ischaemia during hepatic and renal transplantation.
Topics: Animals; Female; Ischemia; Kidney Transplantation; Kinetics; Liver Transplantation; Male; Mitochondr | 1996 |
The effect of sodium pentobarbital on some mitochondrial enzymes.
Topics: Animals; Brain; Electron Transport Complex IV; Gerbillinae; Ischemia; Mitochondria; Monoamine Oxidas | 1978 |
Instrumentation for in vivo cerebral NADH studies in squirrel monkey.
Topics: Animals; Blood Pressure; Brain; Carbon Dioxide; Cerebrovascular Circulation; Halothane; Haplorhini; | 1975 |
Protective effect of a novel imidazole derivative against cerebral anoxia.
Topics: Animals; Asphyxia; Atmospheric Pressure; Cyanides; Electroencephalography; Female; Hypoxia, Brain; I | 1978 |
Barbiturate attenuation of the clinical course and pathologic lesions in a primate stroke model.
Topics: Animals; Cerebrovascular Disorders; Disease Models, Animal; Haplorhini; Ischemia; Macaca mulatta; Mo | 1975 |
Effect of limb ischaemia and scalding on the concentrations of growth hormone and corticosterone in rat plasma.
Topics: Animals; Burns; Corticosterone; Growth Hormone; Hindlimb; Ischemia; Male; Pentobarbital; Rats | 1977 |
[Prolonged traumatic and vascular coma: prognostic and therapeutic indications based on hemodynamic and metabolic studies].
Topics: Blood Gas Analysis; Brain; Carbon Dioxide; Cerebrovascular Circulation; Cerebrovascular Disorders; C | 1976 |
Pressure-flow and volume-flow relationships of the systemic circulation of the dog.
Topics: Abdomen; Anesthetics; Animals; Atrial Function; Blood Circulation; Blood Flow Velocity; Blood Pressu | 1975 |
Influence of pentobarbital and chloralose on metabolic and hemodynamic changes in liver ischemia.
Topics: Adenine Nucleotides; Animals; Chloralose; Hemodynamics; Ischemia; Liver; Male; Pentobarbital; Protei | 1990 |
Ischaemia and tissue pyruvate dehydrogenase activities in the rat: a comparison of the effects of cervical dislocation and pentobarbital anaesthesia.
Topics: Anesthesia, General; Animals; Eating; Fasting; Female; Ischemia; Kidney; Kinetics; Liver; Myocardium | 1986 |
Effects of barbiturate and halothane anesthesia on focal cerebral infarction in the dog.
Topics: Anesthesia; Animals; Barbiturates; Brain; Cerebrovascular Circulation; Cerebrovascular Disorders; Do | 1973 |
Trapping of radioactive microspheres in the pregnant and non-pregnant rabbit.
Topics: Animals; Aorta; Blood Pressure; Cerium Isotopes; Chromium Radioisotopes; Depression, Chemical; Femal | 1974 |
Effects of anesthesia, tachycardia, and autonomic blockade on the Anrep effect in intact dogs.
Topics: Anesthesia, General; Animals; Atropine; Blood Pressure; Cardiac Output; Coronary Circulation; Dogs; | 1974 |
[Ischemic contracture after sleeping pill coma].
Topics: Barbiturates; Coma; Hand; Humans; Ischemia; Muscle Contraction; Pentobarbital | 1971 |
[Preischemic stress and resuscitation time of the heart].
Topics: Adenosine Triphosphate; Anesthesia; Animals; Coronary Vessels; Dogs; Ethyl Ethers; Halothane; Heart | 1969 |
Muscle relaxants on postischemic spinal rigidity in the rat.
Topics: Animals; Chlorpromazine; Contracture; Decerebrate State; Depression, Chemical; Electromyography; Hin | 1970 |
[Electrocorticogram, steady potential of the brain and energy-rich phosphate fractions of the cerebral cortex during anesthetic overdosage, ischemia and cyanide poisoning].
Topics: Adenine Nucleotides; Adenosine Triphosphate; Anesthetics; Animals; Cerebral Cortex; Chloral Hydrate; | 1970 |
Effects of spontaneous ischemia on aerobic metabolism of cortical and medullary homogenates of dog kidney.
Topics: Aging; Animals; Dogs; Female; Glutarates; Ischemia; Isocitrate Dehydrogenase; Kidney; Malate Dehydro | 1970 |
Renal ischemia and anesthesia.
Topics: Anesthesia, Inhalation; Animals; Blood Urea Nitrogen; Ethyl Ethers; Halothane; Ischemia; Kidney; Kid | 1971 |
[Energy rich phosphates and metabolites of energy metabolism in the cerebral cortex in the cat].
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Brain Chemistry; Cats; Cerebral Cortex; Creati | 1965 |