pentobarbital has been researched along with Innate Inflammatory Response in 18 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nerve inflammation is linked to the development of various neurological disorders." | 5.91 | Glycyrrhizae Radix suppresses lipopolysaccharide- and diazepam-induced nerve inflammation in the hippocampus, and contracts the duration of pentobarbital- induced loss of righting reflex in a mouse model. ( Ishida, T; Jobu, K; Kawada, K; Miyamura, M; Morisawa, S; Nishida, M; Tamura, N; Yoshioka, S, 2023) |
| "Neuroinflammation is associated with the development of hypoactive delirium, which results in poor clinical outcomes." | 5.72 | Yokukansan suppresses neuroinflammation in the hippocampus of mice and decreases the duration of lipopolysaccharide- and diazepam-mediated loss of righting reflex induced by pentobarbital. ( Ishida, T; Jobu, K; Kawada, K; Kawazoe, T; Miyamura, M; Morisawa, S; Nishida, M; Nishimura, S; Tamura, N; Yoshioka, S, 2022) |
| " Isoflurane (ISO), ketamine-xylazine (KX), or pentobarbital (PEN) with or without buprenorphine were administered before scald-burn in 72 rats that were euthanized without anesthesia by decapitation after 24 h and compared with unburned shams." | 3.76 | Impact of anesthesia, analgesia, and euthanasia technique on the inflammatory cytokine profile in a rodent model of severe burn injury. ( Al-Mousawi, AM; Branski, LK; Herndon, DN; Jeschke, MG; Kraft, R; Kulp, GA; Mecott, GA; Williams, FN, 2010) |
| "Nerve inflammation is linked to the development of various neurological disorders." | 1.91 | Glycyrrhizae Radix suppresses lipopolysaccharide- and diazepam-induced nerve inflammation in the hippocampus, and contracts the duration of pentobarbital- induced loss of righting reflex in a mouse model. ( Ishida, T; Jobu, K; Kawada, K; Miyamura, M; Morisawa, S; Nishida, M; Tamura, N; Yoshioka, S, 2023) |
| "Neuroinflammation is associated with the development of hypoactive delirium, which results in poor clinical outcomes." | 1.72 | Yokukansan suppresses neuroinflammation in the hippocampus of mice and decreases the duration of lipopolysaccharide- and diazepam-mediated loss of righting reflex induced by pentobarbital. ( Ishida, T; Jobu, K; Kawada, K; Kawazoe, T; Miyamura, M; Morisawa, S; Nishida, M; Nishimura, S; Tamura, N; Yoshioka, S, 2022) |
| "The pentobarbital effect was significant within 3 days of surgery and persisted through the remainder of the testing period." | 1.37 | Deleterious impact of a γ-aminobutyric acid type A receptor preferring general anesthetic when used in the presence of persistent inflammation. ( Boegel, K; Gold, MS; Gyulai, FE; Moore, KK, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (55.56) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 2 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Kawada, K | 2 |
| Ishida, T | 2 |
| Jobu, K | 2 |
| Morisawa, S | 2 |
| Kawazoe, T | 1 |
| Nishida, M | 2 |
| Nishimura, S | 1 |
| Tamura, N | 2 |
| Yoshioka, S | 2 |
| Miyamura, M | 2 |
| Huang, F | 1 |
| Zhang, Y | 1 |
| Xu, Y | 1 |
| Xiang, W | 1 |
| Xie, C | 1 |
| Al-Mousawi, AM | 1 |
| Kulp, GA | 1 |
| Branski, LK | 1 |
| Kraft, R | 1 |
| Mecott, GA | 1 |
| Williams, FN | 1 |
| Herndon, DN | 1 |
| Jeschke, MG | 1 |
| Boegel, K | 1 |
| Gyulai, FE | 1 |
| Moore, KK | 1 |
| Gold, MS | 1 |
| MOSS, JN | 1 |
| FRAZIER, CV | 1 |
| MARTIN, GJ | 1 |
| SVANES, K | 1 |
| YELNOSKY, J | 1 |
| FIELD, WE | 1 |
| Holt, S | 1 |
| Comelli, F | 1 |
| Costa, B | 1 |
| Fowler, CJ | 1 |
| Gradl, G | 1 |
| Gaida, S | 1 |
| Finke, B | 1 |
| Lindenblatt, N | 1 |
| Gierer, P | 1 |
| Menger, MD | 1 |
| Mittlmeier, T | 1 |
| Vollmar, B | 1 |
| Reanmongkol, W | 1 |
| Matsumoto, K | 1 |
| Watanabe, H | 1 |
| Subhadhirasakul, S | 1 |
| Sakai, S | 1 |
| Giagnoni, G | 1 |
| Marsi, A | 1 |
| Parolaro, D | 1 |
| Sala, M | 1 |
| Gori, E | 1 |
| Barbieri, EJ | 1 |
| Ciaccio, EI | 1 |
| Fujihira, E | 1 |
| Whitehouse, MW | 1 |
| Bhattacharya, SK | 1 |
| Das, N | 1 |
| Sarkar, MK | 1 |
| Haas, H | 1 |
| Fischer, HL | 1 |
| Lamb, D | 1 |
| Roberts, G | 1 |
| Syrkin, AB | 1 |
| Plotnikov, NP | 1 |
| Zaĭtseva, LA | 1 |
| Bodiagin, DA | 1 |
18 other studies available for pentobarbital and Innate Inflammatory Response
| Article | Year |
|---|---|
Yokukansan suppresses neuroinflammation in the hippocampus of mice and decreases the duration of lipopolysaccharide- and diazepam-mediated loss of righting reflex induced by pentobarbital.
Topics: Animals; Delirium; Diazepam; Drugs, Chinese Herbal; Glycyrrhizic Acid; Hippocampus; Inflammation; In | 2022 |
Glycyrrhizae Radix suppresses lipopolysaccharide- and diazepam-induced nerve inflammation in the hippocampus, and contracts the duration of pentobarbital- induced loss of righting reflex in a mouse model.
Topics: Animals; Diazepam; Drugs, Chinese Herbal; Glycyrrhiza; Glycyrrhizic Acid; Hippocampus; Inflammation; | 2023 |
Analgesic, anti-inflammatory and sedative/hypnotic effects of Icaritin, and its effect on chloride influx in mouse brain cortical cells.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Brain; Chlorides; Cyclooxygenase 2; Ear; Female; Flav | 2019 |
Impact of anesthesia, analgesia, and euthanasia technique on the inflammatory cytokine profile in a rodent model of severe burn injury.
Topics: Acute-Phase Reaction; Analgesia; Analgesics; Anesthesia, General; Anesthetics; Animals; Buprenorphin | 2010 |
Deleterious impact of a γ-aminobutyric acid type A receptor preferring general anesthetic when used in the presence of persistent inflammation.
Topics: Adrenergic alpha-Agonists; Anesthesia, General; Anesthetics, General; Animals; Behavior, Animal; Exc | 2011 |
BROMELAINS. THE PHARMACOLOGY OF THE ENZYMES.
Topics: Animals; Blood Pressure Determination; Bromelains; Dogs; Endopeptidases; Inflammation; Lagomorpha; M | 1963 |
STUDIES IN HYPOTHERMIA. II. THE INFLUENCE OF DEEP HYPOTHERMIA ON THE FORMATION OF FLUID EXUDATE IN ACUTE INFLAMMATION IN MICE.
Topics: Anesthesia; Anesthesia, Intravenous; Anesthesiology; Animals; Body Fluids; Capillary Permeability; E | 1964 |
A PRELIMINARY REPORT ON THE USE OF A COMBINATION OF DROPERIDOL AND FENTANYL CITRATE IN VETERINARY MEDICINE.
Topics: Analgesics; Analgesics, Non-Narcotic; Animals; Antipyretics; Behavior, Animal; Benperidol; Birds; Ca | 1964 |
Inhibitors of fatty acid amide hydrolase reduce carrageenan-induced hind paw inflammation in pentobarbital-treated mice: comparison with indomethacin and possible involvement of cannabinoid receptors.
Topics: Amidohydrolases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Brain; Camphanes; Can | 2005 |
Supernatant of traumatized muscle induces inflammation and pain, but not microcirculatory perfusion failure and apoptotic cell death.
Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Death; Edema; Hemodynamics; In Situ | 2005 |
Antinociceptive and antipyretic effects of alkaloids extracted from the stem bark of Hunteria zeylanica.
Topics: Acetates; Acetic Acid; Administration, Oral; Alkaloids; Analgesics; Analgesics, Non-Narcotic; Animal | 1994 |
Serum corticosterone as a quantitative test of the phlogistic potency of various agents topically applied in the rat.
Topics: Administration, Topical; Adrenal Glands; Animals; Ascorbic Acid; Corticosterone; Croton Oil; Dexamet | 1976 |
Depression of drug metabolism in the mouse by a combination of Mycobacterium butyricum and anaesthetics.
Topics: Anesthetics; Animals; Depression, Chemical; Inflammation; Ketamine; Male; Mixed Function Oxygenases; | 1979 |
Pathobiodynamics: reduced ascorbate excretion by rats with severe inflammation.
Topics: Animals; Arthritis, Experimental; Ascorbic Acid; Glucaric Acid; Inflammation; Liver; Male; Pentobarb | 1977 |
Inhibition of carrageenin-induced pedal oedema in rats by immobilisation stress.
Topics: 5,6-Dihydroxytryptamine; Adrenalectomy; Animals; Anti-Inflammatory Agents; Carrageenan; Edema; Foot | 1987 |
[Effect of inflammatory reactions on the concentration of corticosterone in rat plasma].
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Anhydrides; Animals; Carrageenan; Corticosterone; Croto | 1969 |
Starch and talc emboli in drug addicts' lungs.
Topics: Acetaminophen; Adult; Alcohols; Amobarbital; Animals; Barbiturates; Female; Foreign-Body Reaction; H | 1972 |
[Pharmacological properties of 20 antibiotic isolated from Aspergillus fumigatus].
Topics: Adrenal Glands; Animals; Antibiotics, Antineoplastic; Aspergillus; Behavior, Animal; Blood Pressure; | 1969 |