pentobarbital has been researched along with Injury, Myocardial Reperfusion in 13 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neither halothane nor sevoflurane protected the heart against the effects of acute and severe regional myocardial ischemia." | 7.70 | Anesthetic modulation of myocardial ischemia and reperfusion injury in pigs: comparison between halothane and sevoflurane. ( Coetzee, A; Coetzee, J; Conradie, S, 1999) |
| "Using canine coronary artery ligation/reperfusion and adrenaline arrhythmia models, we determined the effects of azimilide, a class III antiarrhythmic agent, E-1-[[(5-(4-chlorophenyl)-2-furanyl) methylene]-amino]-3-[4-(4-methyl-1-piperazinyl)butyl]-2,4-imidazolidi nedione dihydrochloride." | 7.70 | Effects of azimilide, a KV(r) and KV(s) blocker, on canine ventricular arrhythmia models. ( Chino, D; Hashimoto, K; Xue, Y; Yamada, C, 1999) |
| "The severity and incidences of arrhythmias induced by left coronary artery occlusion (7 min) and reperfusion (7 min) were compared in two groups of rats anaesthetized by using urethane (1." | 7.69 | Comparison of sodium pentobarbitone and urethane anaesthesia in a rat model of coronary artery occlusion and reperfusion arrhythmias: interaction with L-NAME. ( Guc, MO; Iskit, AB, 1996) |
| " Pentobarbital had no effect on arrhythmias, whereas thiopental was antiarrhythmic." | 3.76 | Comparison of thiopental, urethane, and pentobarbital in the study of experimental cardiology in rats in vivo. ( Bialka, S; Krzeminski, TF; Mitrega, K; Porc, M; Zorniak, M, 2010) |
| "Neither halothane nor sevoflurane protected the heart against the effects of acute and severe regional myocardial ischemia." | 3.70 | Anesthetic modulation of myocardial ischemia and reperfusion injury in pigs: comparison between halothane and sevoflurane. ( Coetzee, A; Coetzee, J; Conradie, S, 1999) |
| "Using canine coronary artery ligation/reperfusion and adrenaline arrhythmia models, we determined the effects of azimilide, a class III antiarrhythmic agent, E-1-[[(5-(4-chlorophenyl)-2-furanyl) methylene]-amino]-3-[4-(4-methyl-1-piperazinyl)butyl]-2,4-imidazolidi nedione dihydrochloride." | 3.70 | Effects of azimilide, a KV(r) and KV(s) blocker, on canine ventricular arrhythmia models. ( Chino, D; Hashimoto, K; Xue, Y; Yamada, C, 1999) |
| "The severity and incidences of arrhythmias induced by left coronary artery occlusion (7 min) and reperfusion (7 min) were compared in two groups of rats anaesthetized by using urethane (1." | 3.69 | Comparison of sodium pentobarbitone and urethane anaesthesia in a rat model of coronary artery occlusion and reperfusion arrhythmias: interaction with L-NAME. ( Guc, MO; Iskit, AB, 1996) |
| "8 g/kg), and a contribution of diazepam with ketamine hydrochloride (D+K, 10 + 100 mg/kg) anesthesia on the incidence of ischemia/ reperfusion-induced arrhythmias in rats." | 3.69 | Influence of anesthetics on the incidence of reperfusion-induced arrhythmias and sudden death in rats. ( Baczkó, I; Leprán, I; Papp, JG, 1997) |
| "Propofol pretreatment before reperfusion, or propofol conditioning, has been shown to be cardioprotective, while its mechanism is unclear." | 1.46 | Activation of Endocannabinoid Receptor 2 as a Mechanism of Propofol Pretreatment-Induced Cardioprotection against Ischemia-Reperfusion Injury in Rats. ( Fu, HL; Lu, Y; Sun, HJ; Wang, HW; Wang, SR; Xu, WY; Yang, F; Yao, XY; Yuan, HB; Zhang, H, 2017) |
| "Cromakalim pretreatment (both when given throughout the experiment and when not present in the reperfusion buffer) resulted in significant improvements in the reperfusion function." | 1.28 | The protective effects of cromakalim and pinacidil on reperfusion function and infarct size in isolated perfused rat hearts and anesthetized dogs. ( Dzwonczyk, S; Grover, GJ; Parham, CS; Sleph, PG, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 5 (38.46) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, HJ | 1 |
| Lu, Y | 1 |
| Wang, HW | 1 |
| Zhang, H | 1 |
| Wang, SR | 1 |
| Xu, WY | 1 |
| Fu, HL | 1 |
| Yao, XY | 1 |
| Yang, F | 1 |
| Yuan, HB | 1 |
| Behmenburg, F | 1 |
| van Caster, P | 1 |
| Bunte, S | 1 |
| Brandenburger, T | 1 |
| Heinen, A | 1 |
| Hollmann, MW | 1 |
| Huhn, R | 1 |
| Shekarforoush, S | 1 |
| Fatahi, Z | 1 |
| Safari, F | 1 |
| Larsen, JR | 1 |
| Aagaard, S | 1 |
| Lie, RH | 1 |
| Sloth, E | 1 |
| Hasenkam, JM | 1 |
| Zorniak, M | 1 |
| Mitrega, K | 1 |
| Bialka, S | 1 |
| Porc, M | 1 |
| Krzeminski, TF | 1 |
| Karlsson, LO | 1 |
| Zhou, AX | 1 |
| Larsson, E | 1 |
| Aström-Olsson, K | 1 |
| Månsson, C | 1 |
| Akyürek, LM | 1 |
| Grip, L | 1 |
| Wang, QD | 1 |
| Tokuno, S | 1 |
| Valen, G | 1 |
| Sjöquist, PO | 1 |
| Thorén, P | 1 |
| Iskit, AB | 1 |
| Guc, MO | 1 |
| Baczkó, I | 1 |
| Leprán, I | 1 |
| Papp, JG | 1 |
| Conradie, S | 1 |
| Coetzee, A | 1 |
| Coetzee, J | 1 |
| Xue, Y | 1 |
| Yamada, C | 1 |
| Chino, D | 1 |
| Hashimoto, K | 1 |
| Grover, GJ | 1 |
| Dzwonczyk, S | 1 |
| Parham, CS | 1 |
| Sleph, PG | 1 |
| Manning, AS | 1 |
| Crome, R | 1 |
| Klein, N | 1 |
| Hearse, DJ | 1 |
| Maguire, ME | 1 |
13 other studies available for pentobarbital and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Activation of Endocannabinoid Receptor 2 as a Mechanism of Propofol Pretreatment-Induced Cardioprotection against Ischemia-Reperfusion Injury in Rats.
Topics: Animals; Apoptosis; Arachidonic Acids; Benzamides; Carbamates; Cells, Cultured; Endocannabinoids; In | 2017 |
Impact of Anesthetic Regimen on Remote Ischemic Preconditioning in the Rat Heart In Vivo.
Topics: Analgesics, Opioid; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Disease Models, Anim | 2018 |
The effects of pentobarbital, ketamine-pentobarbital and ketamine-xylazine anesthesia in a rat myocardial ischemic reperfusion injury model.
Topics: Anesthetics; Animals; Arrhythmias, Cardiac; Hemodynamics; Ketamine; Male; Myocardial Reperfusion Inj | 2016 |
Sevoflurane improves myocardial ischaemic tolerance in a closed-chest porcine model.
Topics: Adjuvants, Anesthesia; Anesthetics, Inhalation; Animals; Disease Models, Animal; Female; Methyl Ethe | 2008 |
Comparison of thiopental, urethane, and pentobarbital in the study of experimental cardiology in rats in vivo.
Topics: Adjuvants, Anesthesia; Anesthetics, Intravenous; Animals; Arrhythmias, Cardiac; Blood Pressure; Dise | 2010 |
Cyclosporine does not reduce myocardial infarct size in a porcine ischemia-reperfusion model.
Topics: Anesthetics; Animals; Apoptosis Inducing Factor; Caspase 3; Cyclosporine; Disease Models, Animal; Dr | 2010 |
Cyclic fluctuations in the cardiac performance of the isolated Langendorff-perfused mouse heart: pyruvate abolishes the fluctuations and has an anti-ischaemic effect.
Topics: Animals; Blood Pressure; Calcium; Electrocardiography; Female; Magnesium; Male; Mice; Mice, Inbred B | 2002 |
Comparison of sodium pentobarbitone and urethane anaesthesia in a rat model of coronary artery occlusion and reperfusion arrhythmias: interaction with L-NAME.
Topics: Adjuvants, Anesthesia; Anesthetics, Intravenous; Animals; Arrhythmias, Cardiac; Arterial Occlusive D | 1996 |
Influence of anesthetics on the incidence of reperfusion-induced arrhythmias and sudden death in rats.
Topics: Anesthetics; Animals; Arrhythmias, Cardiac; Death, Sudden; Diazepam; Hemodynamics; Ketamine; Male; M | 1997 |
Anesthetic modulation of myocardial ischemia and reperfusion injury in pigs: comparison between halothane and sevoflurane.
Topics: Adjuvants, Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Fentanyl; Halotha | 1999 |
Effects of azimilide, a KV(r) and KV(s) blocker, on canine ventricular arrhythmia models.
Topics: Anesthetics; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dogs; Epinephrine; Female; Halot | 1999 |
The protective effects of cromakalim and pinacidil on reperfusion function and infarct size in isolated perfused rat hearts and anesthetized dogs.
Topics: Animals; Benzopyrans; Blood Pressure; Cromakalim; Dogs; Female; Guanidines; In Vitro Techniques; L-L | 1990 |
Dissociation between reperfusion induced arrhythmias and increases in ventricular alpha 1 receptor density in the anaesthetised rat.
Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Heart Ventricles; Male; Myocardial Reperfusion Inju | 1989 |