Page last updated: 2024-11-02

pentobarbital and Injuries, Spinal Cord

pentobarbital has been researched along with Injuries, Spinal Cord in 11 studies

Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.

Research Excerpts

ExcerptRelevanceReference
"The pulmonary index (100 x wet lung weight/body weight) was 0."1.33Importance of anesthesia for the genesis of neurogenic pulmonary edema in spinal cord injury. ( Borges, G; Cambiucci, EC; de Almeida, AR; Gontijo, JA; Leal Filho, MB; Metze, K; Morandin, RC, 2005)
"Late halothane treatment was ineffective when given as early as 10 minutes postinjury while both the electrophysiological and hemodynamic effects of halothane vs."1.29Halothane anesthesia is neuroprotective in experimental spinal cord injury: early hemodynamic mechanisms of action. ( Agresta, CA; Kelly, G; Lee, WA; Mendez, AA; Sabato, S; Salzman, SK, 1993)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's2 (18.18)18.2507
2000's5 (45.45)29.6817
2010's1 (9.09)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Davis, JA1
Bopp, AC1
Henwood, MK1
Bean, P1
Grau, JW2
Nout, YS1
Beattie, MS1
Bresnahan, JC1
Ho, SM1
Waite, PM1
Tetik, O1
Islamoğlu, F1
Göncü, T1
Cekirdekçi, A1
Büket, S1
Leal Filho, MB1
Morandin, RC1
de Almeida, AR1
Cambiucci, EC1
Borges, G1
Gontijo, JA1
Metze, K1
Washburn, SN1
Patton, BC1
Ferguson, AR1
Hudson, KL1
Salzman, SK2
Lee, WA2
Sabato, S2
Mendez, AA2
Agresta, CA2
Kelly, G1
Duke, M1
Advokat, C1
Parker, AJ1
Ingersoll, EB1
Choi, IH1
Fonseca, AS1
Freeman, GM1
Feldman, H1
Hillman, H1

Other Studies

11 other studies available for pentobarbital and Injuries, Spinal Cord

ArticleYear
General Anesthesia Blocks Pain-Induced Hemorrhage and Locomotor Deficits After Spinal Cord Injury in Rats.
    Journal of neurotrauma, 2023, Volume: 40, Issue:23-24

    Topics: Anesthesia, General; Anesthetics; Animals; Contusions; Hemorrhage; Humans; Isoflurane; Pain; Pentoba

2023
Severity of locomotor and cardiovascular derangements after experimental high-thoracic spinal cord injury is anesthesia dependent in rats.
    Journal of neurotrauma, 2012, Mar-20, Volume: 29, Issue:5

    Topics: Anesthetics; Animals; Blood Pressure; Cardiovascular System; Disease Models, Animal; Female; Heart R

2012
Effects of different anesthetics on the paired-pulse depression of the h reflex in adult rat.
    Experimental neurology, 2002, Volume: 177, Issue:2

    Topics: Administration, Inhalation; Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Disease Models, Ani

2002
Reduction of spinal cord injury with pentobarbital and hypothermia in a rabbit model.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2002, Volume: 24, Issue:6

    Topics: Adjuvants, Anesthesia; Animals; Disease Models, Animal; Hypothermia, Induced; Pentobarbital; Rabbits

2002
Importance of anesthesia for the genesis of neurogenic pulmonary edema in spinal cord injury.
    Neuroscience letters, 2005, Jan-10, Volume: 373, Issue:2

    Topics: Anesthetics, General; Animals; Blood Pressure; Ketamine; Lung; Microscopy, Electron, Transmission; P

2005
Exposure to intermittent nociceptive stimulation under pentobarbital anesthesia disrupts spinal cord function in rats.
    Psychopharmacology, 2007, Volume: 192, Issue:2

    Topics: Animals; Behavior, Animal; Conditioning, Operant; Electroshock; Hindlimb; Hypnotics and Sedatives; M

2007
Halothane anesthesia is neuroprotective in experimental spinal cord injury: early hemodynamic mechanisms of action.
    Research communications in chemical pathology and pharmacology, 1993, Volume: 80, Issue:1

    Topics: Anesthesia, Inhalation; Animals; Drug Interactions; Evoked Potentials, Somatosensory; Halothane; Hem

1993
Pentobarbital-induced modulation of flexor and H-reflexes in spinal rats.
    Brain research, 2000, Oct-27, Volume: 881, Issue:2

    Topics: Adjuvants, Anesthesia; Animals; Baclofen; Electric Stimulation; H-Reflex; Male; Muscle Relaxants, Ce

2000
Comparison of the averaged evoked cisterna cerebellomedullaris potential, cortical potential, and neurologic examination in the diagnosis of spinal cord injury of the dog.
    American journal of veterinary research, 1978, Volume: 39, Issue:11

    Topics: Anesthesia; Animals; Cerebral Cortex; Dog Diseases; Dogs; Evoked Potentials; Female; Male; Neurologi

1978
Anesthesia influences the outcome from experimental spinal cord injury.
    Brain research, 1990, Jun-25, Volume: 521, Issue:1-2

    Topics: Anesthesia; Animals; Blood Pressure; Evoked Potentials, Somatosensory; Halothane; Male; Nitrous Oxid

1990
A clinical description of death in rats and the effect of various conditions on the time untile cessation of ventricular contraction following section between the brain and spinal cord.
    British journal of experimental pathology, 1969, Volume: 50, Issue:2

    Topics: Age Factors; Animals; Animals, Newborn; Brain; Death; Electrocardiography; Female; Heart; Heart Vent

1969