pentobarbital has been researched along with Infarction, Middle Cerebral Artery in 6 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We compared microregional O2 balance in cerebral ischemia-reperfusion during pentobarbital and isoflurane anesthesia." | 7.81 | Local O2 Balance in Cerebral Ischemia-Reperfusion Improved during Pentobarbital Compared with Isoflurane Anesthesia. ( Barsoum, S; Chi, OZ; Liu, X; Rah, KH; Weiss, HR, 2015) |
| "To compare the effects of pentobarbital and propofol on the outcome of focal cerebral ischemia model, and to evaluate the availability of propofol in setting the focal cerebral ischemia." | 7.72 | [Comparison of pentobarbital and propofol on the outcome of focal cerebral ischemia model in rats]. ( Kang, QY; Li, J; Liu, Y; Zhang, PB; Zhao, JJ, 2004) |
| "Status epilepticus is common in infants and may have long-term consequences on the brain persisting into adulthood." | 5.36 | Harmful effect of kainic acid on brain ischemic damage is not related to duration of status epilepticus. ( Giorgi, FS; Hasson, H; Malhotra, S; Moshé, SL; Rosenbaum, DM, 2010) |
| " We compared microregional O2 balance in cerebral ischemia-reperfusion during pentobarbital and isoflurane anesthesia." | 3.81 | Local O2 Balance in Cerebral Ischemia-Reperfusion Improved during Pentobarbital Compared with Isoflurane Anesthesia. ( Barsoum, S; Chi, OZ; Liu, X; Rah, KH; Weiss, HR, 2015) |
| "To compare the effects of pentobarbital and propofol on the outcome of focal cerebral ischemia model, and to evaluate the availability of propofol in setting the focal cerebral ischemia." | 3.72 | [Comparison of pentobarbital and propofol on the outcome of focal cerebral ischemia model in rats]. ( Kang, QY; Li, J; Liu, Y; Zhang, PB; Zhao, JJ, 2004) |
| "A mouse model of transient (90 min) middle cerebral artery occlusion (MCAO) was established, and western blotting, enzymic activity assay, and fluorescent immunostaining techniques were used." | 1.51 | Involvement of d-amino acid oxidase in cerebral ischaemia induced by transient occlusion of the middle cerebral artery in mice. ( Han, QQ; Liu, H; Mao, XF; Wang, YX; Wang, ZY; Wu, HY; Zhao, MJ, 2019) |
| "Status epilepticus is common in infants and may have long-term consequences on the brain persisting into adulthood." | 1.36 | Harmful effect of kainic acid on brain ischemic damage is not related to duration of status epilepticus. ( Giorgi, FS; Hasson, H; Malhotra, S; Moshé, SL; Rosenbaum, DM, 2010) |
| "The use of pharmacologic coma (PC) to treat status epilepticus (SE) is not always successful, and there are no guidelines for the duration of PC in an attempt to achieve seizure control." | 1.32 | Now we lay them down to sleep: ethical issues with the use of pharmacologic coma for adult status epilepticus. ( Bramstedt, KA; Morris, HH; Tanner, A, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, H | 1 |
| Zhao, MJ | 1 |
| Wang, ZY | 1 |
| Han, QQ | 1 |
| Wu, HY | 1 |
| Mao, XF | 1 |
| Wang, YX | 1 |
| Arbour, RB | 1 |
| Dissin, J | 1 |
| Chi, OZ | 1 |
| Barsoum, S | 1 |
| Rah, KH | 1 |
| Liu, X | 1 |
| Weiss, HR | 1 |
| Hasson, H | 1 |
| Malhotra, S | 1 |
| Giorgi, FS | 1 |
| Rosenbaum, DM | 1 |
| Moshé, SL | 1 |
| Bramstedt, KA | 1 |
| Morris, HH | 1 |
| Tanner, A | 1 |
| Zhang, PB | 1 |
| Liu, Y | 1 |
| Li, J | 1 |
| Zhao, JJ | 1 |
| Kang, QY | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Narcotrend Depth of Anaesthesia Monitor as an Indicator of Seizures and Burst Suppression in the Intensive Care Unit[NCT06067750] | 106 participants (Anticipated) | Observational | 2023-06-27 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 other studies available for pentobarbital and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Involvement of d-amino acid oxidase in cerebral ischaemia induced by transient occlusion of the middle cerebral artery in mice.
Topics: Animals; Brain Ischemia; D-Amino-Acid Oxidase; Disease Models, Animal; Infarction, Middle Cerebral A | 2019 |
Predictive value of the bispectral index for burst suppression on diagnostic electroencephalogram during drug-induced coma.
Topics: Adult; Alcohol Withdrawal Seizures; Cerebral Cortex; Cohort Studies; Consciousness Monitors; Deep Se | 2015 |
Local O2 Balance in Cerebral Ischemia-Reperfusion Improved during Pentobarbital Compared with Isoflurane Anesthesia.
Topics: Anesthetics, Inhalation; Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Infarction, Mi | 2015 |
Harmful effect of kainic acid on brain ischemic damage is not related to duration of status epilepticus.
Topics: Animals; Anticonvulsants; Brain; Brain Ischemia; Infarction, Middle Cerebral Artery; Kainic Acid; Ma | 2010 |
Now we lay them down to sleep: ethical issues with the use of pharmacologic coma for adult status epilepticus.
Topics: Adult; Anticonvulsants; Brain; Brain Edema; Coma; Drug Therapy; Fatal Outcome; Female; Humans; Hypno | 2004 |
[Comparison of pentobarbital and propofol on the outcome of focal cerebral ischemia model in rats].
Topics: Adjuvants, Anesthesia; Anesthetics, Intravenous; Animals; Brain Ischemia; Disease Models, Animal; In | 2004 |