Page last updated: 2024-11-02

pentobarbital and Hypoxia

pentobarbital has been researched along with Hypoxia in 132 studies

Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.

Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.

Research Excerpts

ExcerptRelevanceReference
"Using a previously developed model of acute normobaric hypoxic hypoxia on chick embryos, here we studied at embryonic day 12 the in vitro effect of two positive allosteric modulators of GABA binding, the barbiturate sodium pentobarbital and the neurosteroid allopregnanolone."7.71Acute hypoxic hypoxia alters GABA(A) receptor modulation by allopregnanolone and pentobarbital in embryonic chick optic lobe. ( Fiszer de Plazas, S; Mitridate de Novara, A; Rodríguez Gil, DJ, 2002)
"Cerebral metabolic and vascular effects of hypothermia (30 C) and deep pentobarbital anesthesia, separately and combined, were evaluated in 15 mongrel dogs."7.66Cerebral hypometabolism obtained with deep pentobarbital anesthesia and hypothermia (30 C). ( Behar, MG; Keykhah, MM; Lafferty, JJ; Shapiro, HM; Van Horn, K, 1978)
" The circulatory and respiratory responses to severe arterial hypoxia were studied in normal rabbits, ;de-efferented' rabbits without functioning autonomic effectors, and atropinized animals before anaesthesia and during chloralose-urethane and sodium pentobarbitone anaesthesia."7.64The effects of chloralose-urethane and sodium pentobarbitone anaesthesia on the local and autonomic components of the circulatory response to arterial hypoxia. ( Korner, PI; Langsford, G; Starr, D; Uther, JB; Ward, W; White, SW, 1968)
"Pentobarbital is an anesthetic used mainly in animal studies."5.34The reduction of tumor necrosis factor-alpha release and tissue damage by pentobarbital in the experimental endotoxemia model. ( Chen, HI; Harn, HJ; Hsu, BG; Lee, RP; Li, CH; Liao, KW; Lin, SZ; Tsai, NM; Yang, FL, 2007)
"Pretreatment with pentobarbital Na (30 mg/kg, i."5.28Carbon monoxide (CO)-induced hypoxia in mice: evaluation as an experimental model of cerebral ischemia for drug screening. ( Hiramatsu, Y; Kato, Y; Koida, M; Muguruma, K; Nakamuta, H; Ogawa, Y; Yasuda, K, 1989)
"In the treatment of cerebral infarction, it is important to select drugs for inhibiting development of the pathology."5.27[Superior protective activity of phenytoin against hypoxia in pharmacological screening test]. ( Imaizumi, S; Kinouchi, H; Suzuki, J; Yoshimoto, T, 1986)
" We tested the hypothesis that asphyxia alone can cause cardiorespiratory failure ("failure") in pentobarbital-anesthetized rats."3.80Hypoxia, not hypercapnia, induces cardiorespiratory failure in rats. ( Iscoe, S; Simpson, JA, 2014)
" In vivo, pregnancy rendered respiratory motor output insensitive to otherwise lethal doses of pentobarbital, a barbiturate previously used to categorize the ε subunit."3.78Increased GABA(A) receptor ε-subunit expression on ventral respiratory column neurons protects breathing during pregnancy. ( Behan, M; Crader, SM; Hengen, KB; Johnson, SM; Mitchell, GS; Nelson, NR; Stang, KM; Watters, JJ, 2012)
"Using a previously developed model of acute normobaric hypoxic hypoxia on chick embryos, here we studied at embryonic day 12 the in vitro effect of two positive allosteric modulators of GABA binding, the barbiturate sodium pentobarbital and the neurosteroid allopregnanolone."3.71Acute hypoxic hypoxia alters GABA(A) receptor modulation by allopregnanolone and pentobarbital in embryonic chick optic lobe. ( Fiszer de Plazas, S; Mitridate de Novara, A; Rodríguez Gil, DJ, 2002)
" Three groups of pentobarbital sodium-anesthetized cats were studied with graded reductions in arterial O2 saturation to 50%: 1) a control group with a hematocrit of 31 +/- 1% (mean +/- SE; n = 7); 2) an anemia group with a hematocrit of 21 +/- 1% that underwent an isovolumic exchange transfusion with an albumin solution (n = 8); and 3) a group transfused with an intramolecularly cross-linked hemoglobin solution to decrease hematocrit to 21 +/- 1% (n = 10)."3.70Cerebral blood flow during hypoxic hypoxia with plasma-based hemoglobin at reduced hematocrit. ( Bucci, E; Koehler, RC; Razynska, A; Traystman, RJ; Ulatowski, JA, 1998)
"Systemic dexmedetomidine (DXM) attenuates the cerebral vasodilation induced by hypercapnia and decreases the cerebral blood flow response to hypoxia."3.70Intrathecal dexmedetomidine attenuates hypercapnic but not hypoxic cerebral vasodilation in anesthetized rabbits. ( Dohi, S; Iida, H; Iida, M; Takenaka, M, 2000)
"Anesthesia was induced with 65 and 45 mg/kg pentobarbital in male and female rats, respectively."3.70Experimental critical care in rats: gender differences in anesthesia, ventilation, and gas exchange. ( Camacho, MT; Hon, E; Ramirez, J; Raszynski, A; Sussmane, JB; Torbati, D; Wolfsdorf, J, 1999)
"In pentobarbital sodium-anesthetized, paralyzed, and ventilated rats, systemic hypoxia, produced by intratracheal N2 administration for 20 s, rapidly increased activities of reticulospinal vasomotor neurons in the rostroventolateral reticular nucleus (RVL) of the medulla oblongata (by 23."3.69Medullary vasomotor activity and hypoxic sympathoexcitation in pentobarbital-anesthetized rats. ( Reis, DJ; Sun, MK, 1996)
"Effect of WEB 1881 FU (nebracetam) on hypoxia and ischemia-induced impairment of 2-deoxyglucose (2DG) uptake and CA1 field potentials induced by hypoxia and hypoxia/hypoglycemia (ischemia) in rat brain slices was evaluated and compared to the findings obtained with pentobarbital and idebenone."3.68Neuroprotective effect of WEB 1881 FU (nebracetam) on an ischemia-induced deficit of glucose uptake in rat hippocampal and cerebral cortical slices and CA1 field potential in hippocampal slices. ( Kagami-ishi, Y; Shibata, S; Ueki, S; Watanabe, S, 1992)
"The antihypoxic effect of the newly-synthesized hydroxylamine barbiturate HB-7, compared with the effects of phenobarbital and pentobarbital, was studied in experiments on albino mice, using the following models of hypoxia: hypobaric, anoxic, asphyctic and haemic."3.67Antihypoxic effect of the hydroxylamine derivative HB-7. ( Georgiev, V; Getova, D, 1989)
"To investigate the role of endogenous opioids on ventilatory control in pentobarbitone-anesthetized rats, the opioid antagonists naloxone and naltrexone were studied for their effects on ventilation, arterial blood gases and on ventilatory responses to hypoxia and carbon dioxide."3.67Role of endogenous opioids on ventilation and chemical control of breathing in pentobarbitone-anesthetized rats. ( Chapman, RW; Mauser, PJ, 1987)
"The effect of Piracetam on hypoxia-induced alterations of cerebral cortex electrogenesis is studied."3.67Effect of Piracetam on electrocorticogram and local cerebral glucose utilization in the rat. ( Balasch, J; Grau, M; Montero, JL, 1987)
"Ventilatory responses to CO2 or hypoxia were examined in rabbits during acupuncture anesthesia and compared with responses during pentobarbital anesthesia."3.66Ventilatory responses to carbon dioxide and hypoxia during acupuncture anesthesia in rabbits. ( Homma, I; Kobayashi, K; Koizumi, H; Liao, YH, 1981)
"Cerebral metabolic and vascular effects of hypothermia (30 C) and deep pentobarbital anesthesia, separately and combined, were evaluated in 15 mongrel dogs."3.66Cerebral hypometabolism obtained with deep pentobarbital anesthesia and hypothermia (30 C). ( Behar, MG; Keykhah, MM; Lafferty, JJ; Shapiro, HM; Van Horn, K, 1978)
"10) led to depression of both respiratory frequency and tidal volume, resulting in apnea within 1."3.65Hypoxia-induced tachypnea in carotid-deafferented cats. ( Miller, MJ; Tenney, SM, 1975)
"The ventilatory responses to isocapnic hypoxia and hypercapnia were studied in seven chronically tracheostomized dogs awake and during anesthesia with pentobarbital (30 mg/kg, iv), ketamine, or thiopental (10 and 15 mg/kg, respectively, followed by infusion)."3.65Hypoxic ventilatory drive in dogs during thiopental, ketamine, or pentobarbital anesthesia. ( Cohen, PJ; Hirshman, CA; McCullough, RE; Weil, JV, 1975)
" The circulatory and respiratory responses to severe arterial hypoxia were studied in normal rabbits, ;de-efferented' rabbits without functioning autonomic effectors, and atropinized animals before anaesthesia and during chloralose-urethane and sodium pentobarbitone anaesthesia."3.64The effects of chloralose-urethane and sodium pentobarbitone anaesthesia on the local and autonomic components of the circulatory response to arterial hypoxia. ( Korner, PI; Langsford, G; Starr, D; Uther, JB; Ward, W; White, SW, 1968)
"Pentobarbital is an anesthetic used mainly in animal studies."1.34The reduction of tumor necrosis factor-alpha release and tissue damage by pentobarbital in the experimental endotoxemia model. ( Chen, HI; Harn, HJ; Hsu, BG; Lee, RP; Li, CH; Liao, KW; Lin, SZ; Tsai, NM; Yang, FL, 2007)
"The death is induced by an anoxia in the central nervous system or by a pharmacologic inhibition of essential neuronal functions."1.32[Euthanasia of pregnant animals]. ( Kietzmann, M, 2003)
" Seventy-seven adverse events occurred in 68 (6."1.32Preprocedural fasting state and adverse events in children undergoing procedural sedation and analgesia in a pediatric emergency department. ( Agrawal, D; Gupta, R; Krauss, B; Manzi, SF, 2003)
"Acute fetal hypoxemia was induced repeatedly by reducing uterine blood flow."1.29Effect of drugs on chemoreceptor responsiveness in fetal sheep. ( Baan, J; Boekkooi, PF; Rudolph, AM; Teitel, DF, 1995)
"Pretreatment with pentobarbital Na (30 mg/kg, i."1.28Carbon monoxide (CO)-induced hypoxia in mice: evaluation as an experimental model of cerebral ischemia for drug screening. ( Hiramatsu, Y; Kato, Y; Koida, M; Muguruma, K; Nakamuta, H; Ogawa, Y; Yasuda, K, 1989)
"Pentobarbital sodium is a widely used anesthetic agent that has been demonstrated to attenuate systemic vascular responses to multiple pressors."1.28Pentobarbital attenuates pulmonary vasoconstriction in isolated sheep lungs. ( Martin, LD; Wetzel, RC, 1989)
"Asphyxic anoxia and hypoventilation hypoxia were used as models of general depression."1.27Effect of piracetam in some models of general and local depression of the cortical bioelectrical activity in cats. ( Dimov, S; Moyanova, S; Nikolov, R; Nikolova, M, 1983)
"In the treatment of cerebral infarction, it is important to select drugs for inhibiting development of the pathology."1.27[Superior protective activity of phenytoin against hypoxia in pharmacological screening test]. ( Imaizumi, S; Kinouchi, H; Suzuki, J; Yoshimoto, T, 1986)
"The effect of temperature, either along or in combination with pentobarbital or phenytoin, on survival time in the hypoxic (Flo2 = 0."1.26Influence of hypothermia or hyperthermia alone or in combination with pentobarbital or phenytoin on survival time in hypoxic mice. ( Artru, AA; Michenfelder, JD, 1981)
"The effects of pentobarbital on survival times of mice exposed to oxygen, 5 per cent, were studied over a large dosage range in normal mice and in mice made tolerant to the effect of barbiturates."1.26Barbiturate protection in tolerant and nontolerant hypoxic mice: comparison with hypothermic protection. ( Michenfelder, JD; Steen, PA, 1979)
"In the awake state, arterial hypoxemia is counteracted by a mechanism which tends to normalize the ventilation/perfusion ratio of the lungs by way of a hypoxia-induced vasoconstriction in poorly ventilated areas."1.26Hypoxia-induced vasoconstriction in isolated perfused lungs exposed to injectable or inhalation anesthetics. ( Bjertnaes, LJ, 1977)
"In additional rats, it was found that anoxia, extra anaesthetic, postmortem rough handling, and sham operations did not increase the frequency of dark neurons."1.25The occurrence of dark neurons in the normal and deafferentated lateral vestibular nucleus in the rat: observations by light and electron microscopy. ( Johnson, JE, 1975)
"Both haemorrhage and anoxia caused a rapid fall of p."1.25Factors influencing the electrical potential across the mucosa of rat colon. ( Edmonds, CJ; Marriott, J, 1968)

Research

Studies (132)

TimeframeStudies, this research(%)All Research%
pre-1990103 (78.03)18.7374
1990's10 (7.58)18.2507
2000's12 (9.09)29.6817
2010's6 (4.55)24.3611
2020's1 (0.76)2.80

Authors

AuthorsStudies
Shoemaker, A1
Steelman, K1
Srbu, R1
Bell, HJ1
Saugstad, OD1
Svorc, P2
Petrášová, D1
Simpson, JA1
Iscoe, S1
Dyer, O1
Kannikeswaran, N1
Chen, X1
Sethuraman, U1
Hengen, KB1
Nelson, NR1
Stang, KM1
Johnson, SM1
Crader, SM1
Watters, JJ1
Mitchell, GS1
Behan, M1
Yamazaki, H1
Okazaki, M1
Takeda, R1
Haji, A1
Rodríguez Gil, DJ2
Mitridate de Novara, A1
Fiszer de Plazas, S2
Kietzmann, M1
JILEK, L2
TROJAN, S2
TSUJI, H1
BALAGOT, RC1
SADOVE, MS1
CAMPBELL, CJ1
MURTAGH, JA1
RABER, CF1
HIRAI, K1
ATKINS, G1
MAROTTA, SF1
BRAASCH, D1
BRUMLIK, J1
MIER, M1
PETROVICK, M1
JENSEN, HP1
BECKER, RF1
BONEAU, CA1
SHEARIN, CA1
KING, JE1
AMASSIAN, VE1
WALLER, HJ1
MACY, J1
FELDMAN, S1
BROOM, B1
WAUGH, WH1
HOWARD, RO1
RICHARDSON, DW1
SMITH, MH1
PATTERSON, JL1
BRECKENRIDGE, BM1
NORMAN, JH1
MILLER, JA1
MILLER, FS1
Agrawal, D1
Manzi, SF1
Gupta, R1
Krauss, B1
Yelmen, KN1
Barac-Nieto, M1
Constantinescu, A1
Pina-Benabou, MH1
Rozental, R1
Wang, LW1
Liu, XM1
Lu, GH1
Gao, NN1
Xiao, PG1
Sanborn, PA1
Michna, E1
Zurakowski, D1
Burrows, PE1
Fontaine, PJ1
Connor, L1
Mason, KP1
Yang, FL1
Li, CH1
Hsu, BG1
Tsai, NM1
Lin, SZ1
Harn, HJ1
Chen, HI1
Liao, KW1
Lee, RP1
Yonemura, D1
Kawasaki, K1
Tsuchida, Y1
Fujimura, K1
Withers, HR1
Asegawa, AT1
Landahl, HD1
Schwartze, P1
Göppert, E1
Homma, I2
Kobayashi, K1
Koizumi, H1
Liao, YH1
Dimov, S1
Nikolov, R1
Nikolova, M1
Moyanova, S1
Iriki, M1
Kozawa, E1
Benzi, G1
Arrigoni, E1
Pastoris, O1
Villa, RF1
Dossena, M1
Agnoli, A1
Giuffrida, AM1
Artru, AA1
Michenfelder, JD2
Quatrini, U1
Benigno, A1
Rohlicek, CV1
Polosa, C1
Hughes, MJ1
Kopetzky, MT2
Messiha, F1
Light, K1
Barnes, CD1
Craigen, ML1
Jennett, S2
Forsling, ML2
Ingram, DL1
Stanier, MW1
Lalley, PM1
Bischoff, AM1
Richter, DW1
Boekkooi, PF1
Baan, J1
Teitel, DF1
Rudolph, AM1
Sun, MK1
Reis, DJ2
Anand, A1
Crossley, D1
Altimiras, J1
Wang, T1
Ulatowski, JA1
Bucci, E1
Razynska, A1
Traystman, RJ1
Koehler, RC1
Torbati, D1
Ramirez, J1
Hon, E1
Camacho, MT1
Sussmane, JB1
Raszynski, A1
Wolfsdorf, J1
Takenaka, M1
Iida, H1
Iida, M1
Dohi, S1
Zagvazdin, Y1
Bodo, M1
Sarkadi, A1
Szporny, L1
Viapiano, MS1
Neuhof, H1
Sablofski, I1
Wilhelmi, J1
Hey, D1
Lasch, HG1
Nathan, MA1
Hoff, JT1
Steen, PA1
Cherniack, NS1
von Euler, C1
Kao, FF1
Lafferty, JJ1
Keykhah, MM2
Shapiro, HM1
Van Horn, K1
Behar, MG1
Scanlon, TS1
Benumof, JL1
Wahrenbrock, EA1
Nelson, WL1
Hughes, M1
Barnes, C1
Bjertnaes, LJ1
Hiraoka, M1
Shimamura, M1
Unger, M1
Atkins, M1
Briscoe, WA1
King, TK1
Phillipson, EA1
Kozar, LF1
Murphy, E1
Huang, TT1
Rejaie, I1
Lewis, SR1
Miller, MJ1
Tenney, SM1
Johnson, JE1
Hirshman, CA2
McCullough, RE2
Cohen, PJ2
Weil, JV2
Griffiths, IR1
Rowan, JO1
Crawford, RA1
Keizer, HJ1
Van Putten, LM1
Shibata, S1
Kagami-ishi, Y1
Ueki, S1
Watanabe, S1
Johnson, DH1
Chang, PC1
Hurst, TS1
Reynolds, FB1
Lang, SA1
Mayers, I1
Jacobi, MS1
Gershan, WM1
Thach, BT1
Koida, M1
Nakamuta, H1
Yasuda, K1
Muguruma, K1
Hiramatsu, Y1
Ogawa, Y1
Kato, Y1
Yamahara, J1
Yamada, T1
Kitani, T1
Naitoh, Y1
Fujimura, H1
Yamamoto, M2
Kawabata, S2
Shimizu, M2
Fregosi, RF1
Bartlett, D1
Getova, D1
Georgiev, V1
Wetzel, RC1
Martin, LD1
Ueda, H1
Hashimoto, T1
Furuya, E1
Tagawa, K1
Kitagawa, K1
Matsumoto, M1
Yoneda, S1
Kimura, K1
Kamada, T1
Imaizumi, S1
Suzuki, J1
Kinouchi, H1
Yoshimoto, T1
Mauser, PJ1
Chapman, RW1
Okuyama, S1
Karasawa, Y1
Shiratsuchi, A1
Araki, H1
Aihara, H1
Smith, DS1
O'Neil, JJ1
Harp, JR1
Grau, M1
Montero, JL1
Balasch, J1
Carlsson, AJ1
Hedenstierna, G1
Bindslev, L1
Tatár, M1
Korpás, J1
Polácek, H1
Záhradný, V1
St John, WM1
Bledsoe, TA1
Németh, S1
Vigas, M1
Galindo, A1
Coulter, DB1
Reece, WO1
Small, LL1
Snodgrass, RR1
Lehotay, DC1
Murphy, BE1
Webb-Peploe, MM1
Shepherd, JT1
Duyckaerts, C1
Tomlin, PJ1
Ullmann, E1
Jones, RL1
King, EG1
Milne, N1
Hill, RP1
Bush, RS1
Sylvester, JT1
Whipp, BJ1
Wasserman, K1
Angel, A1
Berridge, DA1
Unwin, J1
Cohen, RS1
Nisbet, HI1
Creighton, RE1
Steward, DJ1
McDonald, P1
Savolainen, VP1
Kramer, MF1
Poort, C1
Faupel, RP1
Seitz, HJ1
Tarnowski, W1
Thiemann, V1
Weiss, C1
Potondi, A1
Csalay, L1
Mok, AC1
Mogenson, GJ1
Ylitalo, P1
Susmano, A1
Passovoy, M1
Carleton, RA1
Wood, DW1
Downes, JJ1
Lecks, HI1
Baumel, I2
DeFeo, JJ2
Lal, H2
Fregly, MJ1
Yoshino, Y2
Elliott, KA2
Knudsen, J1
van Dyke, DH1
Cserr, H1
Barlow, CF1
Agadzhanian, NA1
Shevchenko, IuV1
Shimizu, H1
Edmonds, CJ1
Marriott, J1
Morada, AO1
Green, JH1
Heffron, PF1
Campbell, AG1
Milligan, JE2
Talner, NS2
Korner, PI1
Langsford, G1
Starr, D1
Uther, JB1
Ward, W1
White, SW1
Dilts, PV1
Brinkman, CR1
Kirschbaum, TH1
Assali, NS1
Kumar, S1
Srivastava, S1
Gjessing, J1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Do Patients Need Pre-Procedural Fasting for Coronary Artery Procedures?[NCT02562638]240 participants (Anticipated)Interventional2015-10-31Not yet recruiting
Can Medical Clowns Prevent the Usage of Sedation During the Performance of EEG in Young Children[NCT05257096]100 participants (Anticipated)Interventional2019-05-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for pentobarbital and Hypoxia

ArticleYear
Splanchnic blood flow during anesthesia.
    International anesthesiology clinics, 1969,Summer, Volume: 7, Issue:2

    Topics: Abdomen; Anesthesia, Conduction; Anesthetics; Animals; Blood Flow Velocity; Blood Glucose; Carbon Di

1969

Other Studies

131 other studies available for pentobarbital and Hypoxia

ArticleYear
Disparity in the effect of morphine on eupnea and gasping in anesthetized spontaneously breathing adult rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2020, 11-01, Volume: 319, Issue:5

    Topics: Analgesics, Opioid; Animals; Apnea; Dose-Response Relationship, Drug; Hypnotics and Sedatives; Hypox

2020
50 Years Ago in The Journal of Pediatrics: The Effect of Pretreatment with Pentobarbital, Meperidine, or Hyperbaric Oxygen on the Response to Anoxia and Resuscitation in Newborn Rabbits.
    The Journal of pediatrics, 2018, Volume: 195

    Topics: Animals; Animals, Newborn; Combined Modality Therapy; Hyperbaric Oxygenation; Hypoxia; Meperidine; N

2018
Arterial pH and blood gas values in rats under three types of general anesthesia: a chronobiological study.
    Physiological research, 2018, 11-14, Volume: 67, Issue:5

    Topics: Anesthesia, General; Anesthetics, General; Animals; Blood Gas Analysis; Chronobiology Phenomena; Dru

2018
Hypoxia, not hypercapnia, induces cardiorespiratory failure in rats.
    Respiratory physiology & neurobiology, 2014, Jun-01, Volume: 196

    Topics: Anesthesia; Animals; Arterial Pressure; Asphyxia; Diaphragm; Heart Failure; Heart Rate; Heart Ventri

2014
US states consider execution by nitrogen gas as lethal injections grind to a halt.
    BMJ (Clinical research ed.), 2015, Mar-23, Volume: 350

    Topics: Capital Punishment; Humans; Hypnotics and Sedatives; Hypoxia; Midazolam; Nitrogen; Pentobarbital; Un

2015
Utility of endtidal carbon dioxide monitoring in detection of hypoxia during sedation for brain magnetic resonance imaging in children with developmental disabilities.
    Paediatric anaesthesia, 2011, Volume: 21, Issue:12

    Topics: Anesthetics, Intravenous; Brain; Carbon Dioxide; Child; Child, Preschool; Conscious Sedation; Develo

2011
Increased GABA(A) receptor ε-subunit expression on ventral respiratory column neurons protects breathing during pregnancy.
    PloS one, 2012, Volume: 7, Issue:1

    Topics: Anesthesia; Animals; Base Sequence; Bicuculline; Brain Stem; Cerebral Cortex; Electrophysiological P

2012
Hypercapnic and hypoxic ventilatory responses in long-term streptozotocin-diabetic rats during conscious and pentobarbital-induced anesthetic states.
    Life sciences, 2002, Nov-22, Volume: 72, Issue:1

    Topics: Aging; Anesthetics; Animals; Blood Glucose; Body Weight; Consciousness; Diabetes Mellitus, Experimen

2002
Acute hypoxic hypoxia alters GABA(A) receptor modulation by allopregnanolone and pentobarbital in embryonic chick optic lobe.
    Brain research, 2002, Nov-08, Volume: 954, Issue:2

    Topics: Anesthetics; Animals; Chick Embryo; GABA Modulators; Hypoxia; Neurons; Optic Lobe, Nonmammalian; Pen

2002
[Euthanasia of pregnant animals].
    DTW. Deutsche tierarztliche Wochenschrift, 2003, Volume: 110, Issue:5

    Topics: Animals; Euthanasia, Animal; Female; Hypnotics and Sedatives; Hypoxia; Pentobarbital; Pregnancy; Pre

2003
[Influences on resistance of the body against oligemia and ischemia of the CNS during the course of ontogenesis].
    Ceskoslovenska pediatrie, 1963, Volume: 18

    Topics: Aging; Central Nervous System; Chlorpromazine; Hyperglycemia; Hypoxia; Ischemia; Pentobarbital

1963
[Differences in influencing the course of anoxia and hypoxia of the central nervous system in ontogenesis].
    Sbornik lekarsky, 1962, Volume: 64

    Topics: Aging; Brain; Central Nervous System; Chlorpromazine; Humans; Hypoglycemia; Hypoxia; Pentobarbital

1962
Effect of anesthetics on brain gamma-aminobutyric and glutamic acid levels.
    JAMA, 1963, Feb-23, Volume: 183

    Topics: Amino Acids; Anesthetics; Brain; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hypoxia; Mydria

1963
CHEMICAL AGENTS AND REFLEX CONTROL OF LARYNGEAL GLOTTIS.
    The Annals of otology, rhinology, and laryngology, 1963, Volume: 72

    Topics: Carbon Dioxide; Ether; Glottis; Hyperventilation; Hypoxia; Larynx; Oxygen; Pentobarbital; Pharmacolo

1963
17-HYDROXYCORTICOSTEROID SECRETION DURING HYPOXIA IN ANESTHETIZED DOGS.
    Aerospace medicine, 1963, Volume: 34

    Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adrenocortical Hyperfunction; Anesthesia; Blood

1963
[DECREASED ERYTHROCYTE FLEXIBILITY (INDUCED BY BARBITURATES, BURNS, HYPOXEMIA) AND THEIR EFFECT ON CAPILLARY CIRCULATION].
    Pflugers Archiv fur die gesamte Physiologie des Menschen und der Tiere, 1963, Oct-25, Volume: 278

    Topics: Animals; Barbiturates; Blood Volume Determination; Burns; Capillaries; Dogs; Erythrocytes; Hypoxia;

1963
[EXPERIMENTAL STUDIES ON A FORM OF RESTING TREMOR IN THE EXTREMITIES OF HEALTHY DOGS].
    Pflugers Archiv fur die gesamte Physiologie des Menschen und der Tiere, 1964, Jan-30, Volume: 278

    Topics: Apnea; Dogs; Electrocardiography; Electroencephalography; Electromyography; Extremities; Heart Arres

1964
BEHAVIORAL ALTERATIONS OF YOUNG RATS WITH A HISTORY OF OVERSEDATION AT BIRTH.
    Neurology, 1964, Volume: 14

    Topics: Animals, Newborn; Asphyxia Neonatorum; Female; Fetus; Guinea Pigs; Humans; Hypoxia; Infant, Newborn;

1964
NEURAL MECHANISM OF THE PRIMARY SOMATOSENSORY EVOKED POTENTIAL.
    Annals of the New York Academy of Sciences, 1964, May-08, Volume: 112

    Topics: Anesthesia; Anesthesia, General; Barbiturates; Brain; Cats; Cerebral Cortex; Chloralose; Decamethoni

1964
VISUAL PROJECTIONS TO THE HYPOTHALAMUS AND PREOPTIC AREA.
    Annals of the New York Academy of Sciences, 1964, Sep-10, Volume: 117

    Topics: Brain; Cats; Circadian Rhythm; Electrophysiology; Hypothalamus; Hypoxia; Light; Mononuclear Phagocyt

1964
EFFECT OF HYPOXIA ON THE RABBIT DURING EXPOSURE TO COLD.
    Nature, 1964, Aug-01, Volume: 203

    Topics: Animals; Body Temperature Regulation; Carbon Dioxide; Cold Temperature; Hypoxia; Pentobarbital; Phys

1964
CIRCULATORY AUTOREGULATION IN THE FULLY ISOLATED KIDNEY AND IN THE HUMORALLY SUPPORTED, ISOLATED KIDNEY.
    Circulation research, 1964, Volume: 15

    Topics: Angiotensins; Blood; Blood Circulation; Blood Pressure; Chloralose; Colloids; Dogs; Homeostasis; Hyp

1964
OXYGEN CONSUMPTION OF ARTERIOLES AND VENULES AS STUDIED IN THE CARTESIAN DIVER.
    Circulation research, 1965, Volume: 16

    Topics: Animals; Arteries; Arterioles; Cricetinae; Hypoxia; Metabolism; Oxygen Consumption; Pentobarbital; P

1965
THE CONVERSION OF PHOSPHORYLASE B TO PHOSPHORYLASE A IN BRAIN.
    Journal of neurochemistry, 1965, Volume: 12

    Topics: Amphetamine; Amphetamines; Brain; Caffeine; Catecholamines; Cocaine; Enzyme Inhibitors; Histocytoche

1965
Factors in neonatal resistance to anoxia. III. Potentiation by narcosis of the effects of hypothermia in the newborn guinea pig.
    American journal of obstetrics and gynecology, 1962, Jul-01, Volume: 84

    Topics: Asphyxia Neonatorum; Chlorpromazine; Guinea Pigs; Humans; Hypothermia; Hypothermia, Induced; Hypoxia

1962
Preprocedural fasting state and adverse events in children undergoing procedural sedation and analgesia in a pediatric emergency department.
    Annals of emergency medicine, 2003, Volume: 42, Issue:5

    Topics: Adjuvants, Anesthesia; Analgesia; Anesthetics, Combined; Child; Child, Preschool; Chloral Hydrate; C

2003
The role of gamma-aminobutyric acid and glutamate for hypoxic ventilatory response in anesthetized rabbits.
    The Tohoku journal of experimental medicine, 2004, Volume: 203, Issue:3

    Topics: Adjuvants, Anesthesia; Anesthesia; Animals; Aorta; Carotid Arteries; Dizocilpine Maleate; Excitatory

2004
Hypoxic rise in cytosolic calcium and renal proximal tubule injury mediated by a nickel-sensitive pathway.
    Experimental biology and medicine (Maywood, N.J.), 2004, Volume: 229, Issue:11

    Topics: Animals; Calcium; Calcium Channel Blockers; Cytoplasm; Female; GABA Modulators; Humans; Hypoxia; Kid

2004
[Primary research of pharmacological effects of PEC on mice].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2004, Volume: 29, Issue:6

    Topics: Animals; Behavior, Animal; Drug Combinations; Drugs, Chinese Herbal; Epimedium; Fatigue; Hypoxia; Ma

2004
Adverse cardiovascular and respiratory events during sedation of pediatric patients for imaging examinations.
    Radiology, 2005, Volume: 237, Issue:1

    Topics: Cardiovascular System; Child, Preschool; Chloral Hydrate; Conscious Sedation; Diagnostic Imaging; Fe

2005
The reduction of tumor necrosis factor-alpha release and tissue damage by pentobarbital in the experimental endotoxemia model.
    Shock (Augusta, Ga.), 2007, Volume: 28, Issue:3

    Topics: Anesthetics; Animals; Apoptosis; Cell Line; Endotoxemia; Humans; Hypoxia; Lipopolysaccharides; Mice;

2007
[Effects of intravitreous injection of several chemicals and inhalation of hypoxic air on rabbit ERG].
    Nihon ganka kiyo, 1966, Volume: 17, Issue:2

    Topics: Animals; Cyanides; Electroretinography; Eye; Hypoxia; Injections; Lidocaine; Pentobarbital; Rabbits;

1966
The effect of oxygen and anaesthesia on radiosensitivity in vivo of epithelial cells of mouse skin.
    The British journal of radiology, 1967, Volume: 40, Issue:473

    Topics: Air; Animals; Epithelium; Hyperbaric Oxygenation; Hypoxia; Mice; Oxygen Consumption; Pentobarbital;

1967
Studies on spleen oxygen tension and radioprotection in mice with hypoxia, serotonin, and p-aminopropiophenone.
    Radiation research, 1967, Volume: 31, Issue:3

    Topics: Animals; Antidotes; Hypoxia; Male; Mice; Nitrites; Oximetry; Oxygen; Pentobarbital; Propiophenones;

1967
[The hypoxia-conditioned EEG arousal stage under the influence of pentobarbital and urethane].
    Experientia, 1967, Mar-15, Volume: 23, Issue:3

    Topics: Animals; Arousal; Electroencephalography; Hypotension; Hypoxia; Nitrogen; Pentobarbital; Rabbits; Ra

1967
Ventilatory responses to carbon dioxide and hypoxia during acupuncture anesthesia in rabbits.
    The American journal of Chinese medicine, 1981,Winter, Volume: 9, Issue:4

    Topics: Acupuncture Therapy; Anesthesia; Animals; Carbon Dioxide; Hypoxia; Partial Pressure; Pentobarbital;

1981
Effect of piracetam in some models of general and local depression of the cortical bioelectrical activity in cats.
    Archives internationales de pharmacodynamie et de therapie, 1983, Volume: 262, Issue:1

    Topics: Adenosine Monophosphate; Animals; Asphyxia; Cats; Cerebral Cortex; Depression, Chemical; Female; Hyp

1983
Renal sympathetic baroreflex during normoxia and during hypoxia in conscious and in anesthetized rabbits.
    Pflugers Archiv : European journal of physiology, 1983, Volume: 398, Issue:1

    Topics: Anesthesia; Animals; Aorta; Blood Pressure; Hypoxia; Kidney; Pentobarbital; Pressoreceptors; Rabbits

1983
Drug action on the metabolic changes induced by acute hypoxia on synaptosomes from the cerebral cortex.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1982, Volume: 2, Issue:2

    Topics: Acute Disease; Animals; Cerebral Cortex; Choline; Cytidine Diphosphate Choline; Dogs; Female; Hypoxi

1982
Influence of hypothermia or hyperthermia alone or in combination with pentobarbital or phenytoin on survival time in hypoxic mice.
    Anesthesia and analgesia, 1981, Volume: 60, Issue:12

    Topics: Animals; Body Temperature; Brain; Energy Metabolism; Hypothermia, Induced; Hypoxia; Lactates; Lactic

1981
[Effect of the administration of sodium pentobarbital on tolerance to acute hypoxia in albino rats].
    Bollettino della Societa italiana di biologia sperimentale, 1981, Feb-15, Volume: 57, Issue:3

    Topics: Acid-Base Equilibrium; Adaptation, Physiological; Animals; Female; Hypoxia; Male; Pentobarbital; Rat

1981
Hypoxic responses of sympathetic preganglionic neurons in the acute spinal cat.
    The American journal of physiology, 1981, Volume: 241, Issue:5

    Topics: Animals; Blood Pressure; Cats; Electric Conductivity; Female; Ganglia, Sympathetic; Hexamethonium Co

1981
Alterations in responses to drugs of atria from white rats acclimated to hypobaric hypoxia.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1981, Volume: 51, Issue:6

    Topics: Acclimatization; Altitude; Animals; Calcium Chloride; Ethanol; Heart; Hypoxia; Male; Norepinephrine;

1981
Pial arterial response to systemic hypoxia in anaesthetised cats.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1981, Volume: 1, Issue:3

    Topics: Animals; Blood Pressure; Cats; Cerebral Arteries; Chloralose; Female; Hypercapnia; Hypoxia; Male; Ox

1981
Plasma antidiurectic hormone during hypoxia and anaesthesia in pigs.
    The Journal of endocrinology, 1980, Volume: 85, Issue:2

    Topics: Anesthesia; Animals; Blood Pressure; Halothane; Hematocrit; Hypoxia; Osmolar Concentration; Pentobar

1980
Serotonin 1A-receptor activation suppresses respiratory apneusis in the cat.
    Neuroscience letters, 1994, May-19, Volume: 172, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cats; Female; Hypoxia; Injections, Intraventricular

1994
Effect of drugs on chemoreceptor responsiveness in fetal sheep.
    Pediatric research, 1995, Volume: 38, Issue:6

    Topics: Acute Disease; Adrenergic beta-Antagonists; Animals; Chemoreceptor Cells; Fetus; Heart Rate; Hypoxia

1995
Medullary vasomotor activity and hypoxic sympathoexcitation in pentobarbital-anesthetized rats.
    The American journal of physiology, 1996, Volume: 270, Issue:2 Pt 2

    Topics: Anesthesia; Animals; Blood Pressure; Hypoxia; Male; Medulla Oblongata; Microinjections; Muscimol; Ne

1996
Reflex stimulation of aortic chemoreceptors through the stellate ganglion during hypoxia and hypotension in cats.
    The Journal of physiology, 1996, Mar-15, Volume: 491 ( Pt 3)

    Topics: Animals; Aorta; Carotid Body; Cats; Chemoreceptor Cells; Ganglionectomy; Hypnotics and Sedatives; Hy

1996
Hypoxia elicits an increase in pulmonary vasculature resistance in anaesthetised turtles (Trachemys scripta).
    The Journal of experimental biology, 1998, Volume: 201, Issue:Pt 24

    Topics: Adrenal Medulla; Anesthesia; Anesthetics; Animals; Atropine; Epinephrine; Hypoxia; Mammals; Norepine

1998
Cerebral blood flow during hypoxic hypoxia with plasma-based hemoglobin at reduced hematocrit.
    The American journal of physiology, 1998, Volume: 274, Issue:6

    Topics: Adjuvants, Anesthesia; Albumins; Anemia; Anesthesia; Animals; Cats; Cerebrovascular Circulation; Hem

1998
Experimental critical care in rats: gender differences in anesthesia, ventilation, and gas exchange.
    Critical care medicine, 1999, Volume: 27, Issue:9

    Topics: Anesthesia; Anesthetics; Animals; Critical Care; Disease Models, Animal; Dose-Response Relationship,

1999
Intrathecal dexmedetomidine attenuates hypercapnic but not hypoxic cerebral vasodilation in anesthetized rabbits.
    Anesthesiology, 2000, Volume: 92, Issue:5

    Topics: Adjuvants, Anesthesia; Administration, Topical; Adrenergic alpha-Agonists; Adrenergic alpha-Antagoni

2000
Cerebroprotective drugs shorten the hypoxia-induced onset of electrical silence in unanesthetized rats.
    Pharmacological research, 2000, Volume: 42, Issue:3

    Topics: Anesthesia; Animals; Cerebrovascular Circulation; Electroencephalography; Ergoloid Mesylates; Flunar

2000
Acute hypoxic hypoxia transiently reduces GABA(A) binding site number in developing chick optic lobe.
    Brain research. Developmental brain research, 2000, Nov-30, Volume: 124, Issue:1-2

    Topics: Acute Disease; Allosteric Regulation; Animals; Binding Sites; Chick Embryo; GABA Modulators; gamma-A

2000
The activation of intravascular coagulation by bromocarbamide.
    International journal of clinical pharmacology and biopharmacy, 1977, Volume: 15, Issue:4

    Topics: Adult; Animals; Blood; Blood Coagulation; Bromisovalum; Disseminated Intravascular Coagulation; Fema

1977
Hypoxemia, atelectasis, and the elevation of arterial pressure and heart rate in paralyzed artificially ventilated rat.
    Life sciences, 1975, Apr-01, Volume: 16, Issue:7

    Topics: Animals; Blood; Blood Pressure; Carbon Dioxide; Ethyl Ethers; Female; Halothane; Heart Rate; Hydroge

1975
Proceedings: arterial blood-gases during increased intracranial pressure in anaesthetized cats.
    British journal of anaesthesia, 1975, Volume: 47, Issue:5

    Topics: Anesthesia, General; Animals; Carbon Dioxide; Cats; Hydrogen-Ion Concentration; Hypoxia; Intracrania

1975
Barbiturate protection in tolerant and nontolerant hypoxic mice: comparison with hypothermic protection.
    Anesthesiology, 1979, Volume: 50, Issue:5

    Topics: Animals; Brain; Dose-Response Relationship, Drug; Drug Tolerance; Hypothermia, Induced; Hypoxia; Mal

1979
Experimentally induced Cheyne-Stokes breathing.
    Respiration physiology, 1979, Volume: 37, Issue:2

    Topics: Animals; Carbon Dioxide; Cats; Cheyne-Stokes Respiration; Hypoxia; Lung; Oxygen; Partial Pressure; P

1979
Cerebral hypometabolism obtained with deep pentobarbital anesthesia and hypothermia (30 C).
    Anesthesiology, 1978, Volume: 49, Issue:3

    Topics: Anesthesia; Animals; Brain; Dogs; Glucose; Hypothermia, Induced; Hypoxia; Lactates; Oxygen; Pentobar

1978
Hypoxic pulmonary vasoconstriction and the ratio of hypoxic lung to perfused normoxic lung.
    Anesthesiology, 1978, Volume: 49, Issue:3

    Topics: Anesthesia, Intravenous; Animals; Dogs; Hypoxia; Pentobarbital; Pulmonary Circulation; Ventilation-P

1978
Effect of adaptation to simulated altitude upon the in vitro response of rat cardiac muscle to barbiturate and ethanol.
    Proceedings of the Western Pharmacology Society, 1978, Volume: 21

    Topics: Acclimatization; Altitude Sickness; Animals; Barbiturates; Ethanol; Heart; Heart Rate; Hypoxia; In V

1978
Hypoxia-induced vasoconstriction in isolated perfused lungs exposed to injectable or inhalation anesthetics.
    Acta anaesthesiologica Scandinavica, 1977, Volume: 21, Issue:2

    Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics; Animals; Diazepam; Dose-Response Relat

1977
Neural mechanisms of the corneal blinking reflex in cats.
    Brain research, 1977, Apr-15, Volume: 125, Issue:2

    Topics: Animals; Brain Stem; Cats; Cornea; Decerebrate State; Electric Stimulation; Electromyography; Evoked

1977
Potentiation of pulmonary vasoconstrictor response with repeated intermittent hypoxia.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1977, Volume: 43, Issue:4

    Topics: Animals; Blood Pressure; Carbon Dioxide; Cardiac Output; Dogs; Hypoxia; Oxygen; Pentobarbital; Pulmo

1977
Respiratory load compensation in awake and sleeping dogs.
    Journal of applied physiology, 1976, Volume: 40, Issue:6

    Topics: Animals; Dogs; Hypercapnia; Hypoxia; Lung Compliance; Pentobarbital; Respiration; Sleep; Tidal Volum

1976
Relative hypoxemia during rhytidoplasty.
    Plastic and reconstructive surgery, 1976, Volume: 58, Issue:1

    Topics: Adult; Aged; Anesthesia, Local; Barbiturates; Dermatologic Surgical Procedures; Humans; Hydroxyzine;

1976
Hypoxia-induced tachypnea in carotid-deafferented cats.
    Respiration physiology, 1975, Volume: 23, Issue:1

    Topics: Anesthesia, Local; Animals; Apnea; Carbon Dioxide; Carotid Body; Carotid Sinus; Catecholamines; Cats

1975
The occurrence of dark neurons in the normal and deafferentated lateral vestibular nucleus in the rat: observations by light and electron microscopy.
    Acta neuropathologica, 1975, Volume: 31, Issue:2

    Topics: Animals; Cell Nucleus; Cell Survival; Denervation; Hypoxia; Male; Neurons; Neurons, Afferent; Pentob

1975
Hypoxic ventilatory drive in dogs during thiopental, ketamine, or pentobarbital anesthesia.
    Anesthesiology, 1975, Volume: 43, Issue:6

    Topics: Anesthesia, Intravenous; Animals; Carbon Dioxide; Dogs; Female; Hypercapnia; Hypoxia; Ketamine; Male

1975
Effect of pentobarbitone on hypoxic ventilatory drive in man: Preliminary study.
    British journal of anaesthesia, 1975, Volume: 47, Issue:9

    Topics: Adult; Female; Heart Rate; Humans; Hypoxia; Male; Oxygen Consumption; Pentobarbital; Physical Fitnes

1975
Spinal cord blood flow measured by a hydrogen clearance technique.
    Journal of the neurological sciences, 1975, Volume: 26, Issue:4

    Topics: Anesthesia, General; Animals; Carbon Dioxide; Chloralose; Dogs; Hydrogen; Hypoxia; Methods; Papio; P

1975
Proceedings: Identification of hypoxic mouse bone marrow CFU in vivo.
    British journal of cancer, 1975, Volume: 32, Issue:6

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Hypoxia; Mice; Nitroimidazoles; Pentobarbital; Radiation Ef

1975
Neuroprotective effect of WEB 1881 FU (nebracetam) on an ischemia-induced deficit of glucose uptake in rat hippocampal and cerebral cortical slices and CA1 field potential in hippocampal slices.
    Japanese journal of pharmacology, 1992, Volume: 58, Issue:3

    Topics: Animals; Benzoquinones; Brain Ischemia; Cerebral Cortex; Deoxyglucose; Electrophysiology; Evoked Pot

1992
Changes in PETCO2 and pulmonary blood flow after bronchial occlusion in dogs.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1992, Volume: 39, Issue:2

    Topics: Airway Obstruction; Animals; Blood Pressure; Bronchi; Carbon Dioxide; Dogs; Halothane; Hypoxia; Intu

1992
Effect of pentobarbital on spontaneous recovery from hypoxic apnoea in mice.
    Respiration physiology, 1991, Volume: 84, Issue:3

    Topics: Animals; Apnea; Body Temperature; Hypoxia; Kinetics; Mice; Pentobarbital; Pulmonary Wedge Pressure;

1991
Carbon monoxide (CO)-induced hypoxia in mice: evaluation as an experimental model of cerebral ischemia for drug screening.
    Japanese journal of pharmacology, 1989, Volume: 51, Issue:2

    Topics: Animals; Brain Ischemia; Carbon Monoxide; Carboxyhemoglobin; Disease Models, Animal; Drug Evaluation

1989
Antianoxic action of evodiamine, an alkaloid in Evodia rutaecarpa fruit.
    Journal of ethnopharmacology, 1989, Volume: 27, Issue:1-2

    Topics: Alkaloids; Animals; Anticonvulsants; Atmospheric Pressure; Dihydroergotoxine; Hypoxia; Male; Mice; P

1989
Pharmacological effects of indeloxazine, a new cerebral activator, on brain functions distinct from other cerebral metabolic enhancers.
    Neuropharmacology, 1989, Volume: 28, Issue:12

    Topics: Animals; Avoidance Learning; Biotransformation; Body Temperature; Brain; Brain Ischemia; Cats; Cauda

1989
Internal intercostal nerve discharges in the cat: influence of chemical stimuli.
    Journal of applied physiology (Bethesda, Md. : 1985), 1989, Volume: 66, Issue:2

    Topics: Action Potentials; Animals; Cats; Chemoreceptor Cells; Female; Hypercapnia; Hypoxia; Intercostal Ner

1989
Cerebral vasodilators potentiate the anti-anoxic activity of indeloxazine hydrochloride, a new cerebral activator.
    Neuropharmacology, 1989, Volume: 28, Issue:3

    Topics: Animals; Antidepressive Agents; Cerebrovascular Circulation; Hypoxia; Male; Mice; Mice, Inbred ICR;

1989
Antihypoxic effect of the hydroxylamine derivative HB-7.
    Acta physiologica et pharmacologica Bulgarica, 1989, Volume: 15, Issue:1

    Topics: Animals; Anticonvulsants; Asphyxia; Atmospheric Pressure; Hydroxylamines; Hypoxia; Mice; Pentobarbit

1989
Pentobarbital attenuates pulmonary vasoconstriction in isolated sheep lungs.
    The American journal of physiology, 1989, Volume: 257, Issue:3 Pt 2

    Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Hypoxia; In Vitro Techniques; Male; Osmol

1989
Changes in aerobic and anaerobic ATP-synthesizing activities in hypoxic mouse brain.
    Journal of biochemistry, 1988, Volume: 104, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aerobiosis; Anaerobiosis; Animals; Brain; Electron Tr

1988
[Superior protective activity of phenytoin against hypoxia in pharmacological screening test].
    No to shinkei = Brain and nerve, 1986, Volume: 38, Issue:2

    Topics: Animals; Atmosphere Exposure Chambers; Cerebral Infarction; Drug Evaluation, Preclinical; Hypoxia; M

1986
Role of endogenous opioids on ventilation and chemical control of breathing in pentobarbitone-anesthetized rats.
    Pharmacology, 1987, Volume: 35, Issue:6

    Topics: Anesthesia; Animals; Blood Gas Analysis; Carbon Dioxide; Endorphins; Hydrogen-Ion Concentration; Hyp

1987
Protective effects of minaprine on the cerebrum of rodents.
    Research communications in chemical pathology and pharmacology, 1988, Volume: 60, Issue:3

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Brain Ischemia; Hypoxia; Male; Mice; Mice, Inb

1988
The influence of fentanyl upon cerebral high-energy metabolites, lactate, and glucose during severe hypoxia in the rat.
    Anesthesiology, 1988, Volume: 69, Issue:4

    Topics: Adenosine Triphosphate; Animals; Brain; Electroencephalography; Energy Metabolism; Fentanyl; Glucose

1988
Effect of Piracetam on electrocorticogram and local cerebral glucose utilization in the rat.
    General pharmacology, 1987, Volume: 18, Issue:2

    Topics: Animals; Brain; Cerebral Cortex; Deoxy Sugars; Deoxyglucose; Electroencephalography; Energy Metaboli

1987
Hypoxia-induced vasoconstriction in human lung exposed to enflurane anaesthesia.
    Acta anaesthesiologica Scandinavica, 1987, Volume: 31, Issue:1

    Topics: Abdomen; Adult; Anesthesia, Inhalation; Anesthesia, Intravenous; Enflurane; Female; Hemodynamics; Hu

1987
Changes induced by severe hypoxia in respiratory defence reflexes in anaesthetized cats.
    Respiration; international review of thoracic diseases, 1986, Volume: 49, Issue:2

    Topics: Anesthesia, Intravenous; Animals; Apnea; Cats; Cough; Female; Hydrogen-Ion Concentration; Hypoxia; M

1986
Comparison of respiratory-related trigeminal, hypoglossal and phrenic activities.
    Respiration physiology, 1985, Volume: 62, Issue:1

    Topics: Animals; Cats; Chemoreceptor Cells; Decerebrate State; Diazepam; Doxapram; Electromyography; Electro

1985
Metabolic and endocrine functions of rats conditioned to Noble-Collip drum trauma.
    Advances in experimental medicine and biology, 1972, Volume: 33, Issue:0

    Topics: Adaptation, Physiological; Anesthesia; Animals; Blood Glucose; Carbon Tetrachloride Poisoning; Catec

1972
Effects of procaine, pentobarbital and halothane on synaptic transmission in the central nervous system.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 169, Issue:2

    Topics: Aminobutyrates; Animals; Cats; Decerebrate State; Electric Stimulation; Halothane; Hypoxia; Iontopho

1969
Continuous recording of erythrocyte counts and hemoglobin concentrations in the dog.
    Laboratory animal science, 1972, Volume: 22, Issue:2

    Topics: Anesthesia, Intravenous; Animals; Automation; Colorimetry; Dog Diseases; Dogs; Epinephrine; Erythroc

1972
Changes in spleen weight, cyclic-AMP content, and serum-corticosterone levels of rats in response to CO2.
    Canadian journal of physiology and pharmacology, 1974, Volume: 52, Issue:6

    Topics: Adrenal Glands; Animals; Carbon Dioxide; Corticosterone; Cyclic AMP; Cyclic GMP; Denervation; Hypoxi

1974
Responses of the superficial limb veins of the dog to changes in temperature.
    Circulation research, 1968, Volume: 22, Issue:6

    Topics: Animals; Blood Pressure; Body Temperature Regulation; Chloralose; Dogs; Forelimb; Ganglionic Blocker

1968
[Role of catecholamines in hypoxia and hyperglycemia induced by injection of cystamine].
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 191, Issue:2

    Topics: Adrenal Medulla; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Glucose;

1971
Death in outpatient dental anaesthetic practice.
    Anaesthesia, 1974, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Aged; Anesthesia, Dental; Anesthesia, General; Anesthesia, Local; Anesthetics; An

1974
Proceedings: Plasma vasopressin and renal concentrating ability in the anaesthetized dog.
    The Journal of endocrinology, 1974, Volume: 63, Issue:2

    Topics: Anesthesia; Animals; Arginine; Dogs; Hypotension; Hypoxia; Kidney Concentrating Ability; Osmolar Con

1974
Evaluation of positive end-expiratory pressure in hypoxemic dogs.
    Journal of applied physiology, 1973, Volume: 35, Issue:2

    Topics: Animals; Cardiac Output; Chloralose; Dogs; Hypoxia; Lung Compliance; Oleic Acids; Oxygen; Oxygen Con

1973
Factors affecting hypoxic KHT tumor cells in mice breathing O2, O2 + CO2 , or hyperbaric oxygen with or without anesthesia.
    Radiology, 1973, Volume: 106, Issue:3

    Topics: Anemia; Anesthesia, General; Animals; Carbon Dioxide; Cell Survival; Hyperbaric Oxygenation; Hypoxia

1973
Ventilatory control during brief infusions of CO2-laden blood in the awake dog.
    Journal of applied physiology, 1973, Volume: 35, Issue:2

    Topics: Animals; Aorta, Thoracic; Carbon Dioxide; Carotid Body; Chemoreceptor Cells; Dogs; Hydrogen-Ion Conc

1973
The effect of anaesthetic agents on primary cortical evoked responses.
    British journal of anaesthesia, 1973, Volume: 45, Issue:8

    Topics: Animals; Blood Pressure; Brain Edema; Carbon Dioxide; Cerebral Cortex; Electric Stimulation; Electro

1973
The effects of hypoxaemia on cerebral blood flow and cerebrospinal fluid pressure in dogs anaesthetized with Althesin, pentobarbitone and methoxyflurane.
    Canadian Anaesthetists' Society journal, 1973, Volume: 20, Issue:6

    Topics: Anesthetics; Animals; Blood; Blood Pressure; Cardiac Output; Cerebrovascular Circulation; Dogs; Hydr

1973
Influence of anaesthetic drugs on amino acid incorporation in the rat pancreas.
    Biochemical pharmacology, 1972, Feb-15, Volume: 21, Issue:4

    Topics: Anesthetics; Animals; Autoradiography; Body Temperature; Depression, Chemical; Ethyl Ethers; Female;

1972
The problem of tissue sampling from experimental animals with respect to freezing technique, anoxia, stress and narcosis. A new method for sampling rat liver tissue and the physiological values of glycolytic intermediates and related compounds.
    Archives of biochemistry and biophysics, 1972, Volume: 148, Issue:2

    Topics: Adenosine Monophosphate; Anesthesia; Animals; Freezing; Hypoxia; In Vitro Techniques; Kidney; Liver;

1972
[Effect of alcohol on experimentally induced cerebral hypoxia].
    Zeitschrift fur Rechtsmedizin. Journal of legal medicine, 1972, Volume: 70, Issue:2

    Topics: Animals; Brain Chemistry; Brain Diseases; Cats; Chloral Hydrate; Ethanol; Hypoxia; Pentobarbital; Ra

1972
An evoked potential study of the projections to the lateral habenular nucleus from the septum and the lateral preoptic area in the rat.
    Brain research, 1972, Aug-25, Volume: 43, Issue:2

    Topics: Action Potentials; Animals; Cerebral Ventricles; Diencephalon; Electric Stimulation; Evoked Potentia

1972
Effect of anaesthetics with excitatory properties, hypoxia, hypercapnia and hypoglycaemia on toxicity of 5HT in rats.
    Annales medicinae experimentalis et biologiae Fenniae, 1972, Volume: 50, Issue:2

    Topics: Anesthetics; Animals; Chloralose; Depression, Chemical; Hydroxybutyrates; Hypercapnia; Hypoglycemia;

1972
Comparison of the effects of two anesthetic agents on the production of hypoxic pulmonary hypertension in dogs.
    American heart journal, 1972, Volume: 84, Issue:2

    Topics: Anesthetics; Animals; Benperidol; Dogs; Fentanyl; Hypertension, Pulmonary; Hypoxia; Neuroleptanalges

1972
The management of respiratory failure in childhood status asthmaticus. Experience with 30 episodes and evolution of a technique.
    The Journal of allergy, 1968, Volume: 42, Issue:5

    Topics: Acid-Base Equilibrium; Acidosis; Asthma; Blood Gas Analysis; Cardiac Tamponade; Child; Chlorpromazin

1968
Differential effect of hypobaric hypoxia on potency of CNS depressants in rats and mice.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1969, Volume: 132, Issue:2

    Topics: Animals; Atmospheric Pressure; Barbiturates; Body Temperature; Central Nervous System; Chloral Hydra

1969
Comments on cross-adaptation.
    Environmental research, 1969, Volume: 2, Issue:5

    Topics: Adaptation, Physiological; Animals; Cold Temperature; Dichlorodiphenyldichloroethane; Dogs; Environm

1969
Effects of various conditions on the movement of carbon atoms derived from glucose into and out of protein in rat brain.
    Canadian journal of biochemistry, 1970, Volume: 48, Issue:3

    Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Autoanalysis; Brain; Carbon Isotopes; Cerebral Cortex;

1970
Incorporation of carbon atoms from glucose into free amino acids in brain under normal and altered conditions.
    Canadian journal of biochemistry, 1970, Volume: 48, Issue:3

    Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Autoanalysis; Brain; Carbon Isotopes;

1970
Effects of acute hypoxia on brain-sensitivity and metabolism of barbiturates in mice.
    Psychopharmacologia, 1970, Volume: 17, Issue:2

    Topics: Animals; Brain; Hypnosis; Hypoxia; Male; Mice; Pentobarbital; Reflex

1970
Duration of hypoxaemia after uncomplicated upper abdominal and thoraco-abdominal operations.
    Anaesthesia, 1970, Volume: 25, Issue:3

    Topics: Adult; Aged; Anesthesia; Arteries; Carbon Dioxide; Female; Gastrectomy; Humans; Hypoxia; Male; Middl

1970
5-Hydroxyindoleacetic acid (5-HIAA) transport by isolated choroid plexus.
    Neurology, 1970, Volume: 20, Issue:4

    Topics: Aminohippuric Acids; Anesthesia; Animals; Biological Transport, Active; Carbon Isotopes; Choroid Ple

1970
[Correlation of changes in different functional systems of the organism due to increasing hypoxia in intact and anesthetized animals].
    Doklady Akademii nauk SSSR, 1971, Volume: 198, Issue:2

    Topics: Anesthesia, General; Animals; Body Temperature; Hypoxia; Muscles; Oxygen Consumption; Pentobarbital;

1971
[Pharmacological and physiological studies on renal circulation. (4). Effects of changes in blood gas tension on the circulation of the perfused kidney].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1967, Nov-20, Volume: 63, Issue:6

    Topics: Acetylcholine; Animals; Blood Gas Analysis; Blood Pressure; Carbon Dioxide; Chloralose; Dogs; Electr

1967
Factors influencing the electrical potential across the mucosa of rat colon.
    The Journal of physiology, 1968, Volume: 194, Issue:2

    Topics: Acetazolamide; Adrenalectomy; Animals; Biological Transport, Active; Blood Vessels; Chlorides; Chlor

1968
Postmortem pulmonary edema. Differential susceptibility in newborn and adult rabbits.
    Archives of pathology, 1968, Volume: 85, Issue:5

    Topics: Age Factors; Animals; Animals, Newborn; Body Weight; Drug Synergism; Heart; Hypoxia; Lidocaine; Lung

1968
Studies upon patterns of activity in single post-ganglionic sympathetic fibres.
    Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 173, Issue:1

    Topics: Action Potentials; Animals; Cats; Ganglia, Autonomic; Heart Conduction System; Hemorrhage; Hypoxia;

1968
The effect of pretreatment with pentobarbital, meperidine, or hyperbaric oxygen on the response to anoxia and resuscitation in newborn rabbits.
    The Journal of pediatrics, 1968, Volume: 72, Issue:4

    Topics: Animals; Animals, Newborn; Female; Hyperbaric Oxygenation; Hypoxia; Meperidine; Pentobarbital; Pregn

1968
The effects of chloralose-urethane and sodium pentobarbitone anaesthesia on the local and autonomic components of the circulatory response to arterial hypoxia.
    The Journal of physiology, 1968, Volume: 199, Issue:2

    Topics: Animals; Atropine; Autonomic Nervous System; Blood Circulation; Chloralose; Heart Conduction System;

1968
Uterine and systemic hemodynamic interrelationships and their response to hypoxia.
    American journal of obstetrics and gynecology, 1969, Jan-01, Volume: 103, Issue:1

    Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Anesthesia, Spinal; Animals; Blood Flow Velocity; B

1969
The effect of pretreatment with hyperbaric oxygen on the response to anoxia and survival on resuscitation in newborn rabbits.
    American journal of obstetrics and gynecology, 1969, Feb-15, Volume: 103, Issue:4

    Topics: Animals; Animals, Newborn; Blood Glucose; Carbon Dioxide; Cardiac Glycosides; Hydrogen-Ion Concentra

1969
Influence of hypoxia and coronary ligation on cardiac arrest in dogs anaesthetized with pentobarbitone.
    British journal of anaesthesia, 1969, Volume: 41, Issue:4

    Topics: Anesthesia, Intravenous; Animals; Coronary Vessels; Dogs; Electrocardiography; Female; Heart Arrest;

1969
Effect of reserpine treatment on cardiovascular response to hypoxia in dog.
    Acta Societatis Medicorum Upsaliensis, 1966, Volume: 71, Issue:5

    Topics: Animals; Cardiovascular System; Dogs; Heart-Lung Machine; Hypoxia; Injections, Intramuscular; Pentob

1966