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pentobarbital and Hypothermia, Accidental

pentobarbital has been researched along with Hypothermia, Accidental in 62 studies

Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.

Research Excerpts

ExcerptRelevanceReference
" This approach was used to study brain-body temperature homeostasis during the development of general anesthesia induced by sodium pentobarbital (50 mg/kg, ip) in rats."7.73Brain and body temperature homeostasis during sodium pentobarbital anesthesia with and without body warming in rats. ( Brown, PL; Kiyatkin, EA, 2005)
"Four groups of rats received chlordiazepoxide (CDP): a) intermittently, experiencing hypothermia and rotarod performance (RR) deficit after test doses (contingency); b) chronically, experiencing hypothermia and RR deficit after test doses; c) intermittently, RR preceding test doses and with protection against hypothermia afforded by exposure to heat lamps (nonexperienced, noncontingency); and d) chronically, RR preceding test doses and with protection against hypothermia."7.68Cellular and learned tolerances to chlordiazepoxide hypothermia and ataxia. ( MacKenzie-Taylor, DR; Rech, RH, 1993)
" The effects of two anaesthetics, sodium pentobarbital and urethane, and the effects of anaesthesia-associated hypothermia on acid-base status and blood gases were studied in rats without assisted ventilation."7.68Differential effects of hypothermia upon blood acid-base state and blood gases in sodium pentobarbital and urethane anaesthetised rats. ( Alfaro, V; Palacios, L, 1992)
"The development of behavioral tolerance to pentobarbital-induced hypothermia, as separable from cellular and metabolic tolerance, was established."7.68Cellular and learned tolerances for pentobarbital hypothermia. ( MacKenzie-Taylor, DR; Rech, RH, 1991)
" In both ovariectomized rats and rats treated with estradiol and progesterone, pentobarbital caused a marked hypothermia and blocked LH hypersecretion."7.67Role of hypothermia in the pentobarbital-induced blockade of luteinizing hormone secretion in female rats. ( Katovich, MJ; Simpkins, JW, 1987)
"In this experiment we investigated inhibitory Pavlovian conditioning in the development of tolerance to pentobarbital-induced hypothermia."7.67Pavlovian inhibitory conditioning and tolerance to pentobarbital-induced hypothermia in rats. ( Hinson, RE; Siegel, S, 1986)
"Rats were given five separate pairings (sequential IP injections) of pentobarbital and lithium chloride, both hypothermia-inducing agents."7.66Attenuation of pentobarbital-elicited hypothermia in rats with a history of pentobarbital-LiCl pairings. ( Taukulis, HK, 1982)
"Based on our previous results and the present data, it should be presumed that presynaptic 5-HT(1A) autoreceptor mechanisms may be involved in the inhibitory effect of spinosin on 8-OH-DPAT-induced hypothermia and also in the potentiating effect of spinosin on pentobarbital-induced LORR in mice."3.78Augmentative effect of spinosin on pentobarbital-induced loss of righting reflex in mice associated with presynaptic 5-HT1A receptor. ( Wang, LE; Yin, YQ; Zhang, XQ; Zhang, YH, 2012)
" We forcibly induced hypothermia in Syrian hamsters by pentobarbital anesthesia combined with cooling of the animals."3.74Central A1-receptor activation associated with onset of torpor protects the heart against low temperature in the Syrian hamster. ( Hirayama, H; Miyazawa, S; Morita, H; Shiina, T; Shimizu, Y; Takewaki, T, 2008)
" This approach was used to study brain-body temperature homeostasis during the development of general anesthesia induced by sodium pentobarbital (50 mg/kg, ip) in rats."3.73Brain and body temperature homeostasis during sodium pentobarbital anesthesia with and without body warming in rats. ( Brown, PL; Kiyatkin, EA, 2005)
"To test if hypothermia, induced by a sustained pentobarbital anesthesia, in rats can reduce ventilatory demands without compromising pulmonary gas-exchange efficiency."3.70Effect of hypothermia on ventilation in anesthetized, spontaneously breathing rats: theoretical implications for mechanical ventilation. ( Camacho, MT; Hultquist, K; Raszynski, A; Sussmane, JB; Torbati, D; Totapally, BR; Wolfsdorf, J, 2000)
"Four groups of rats received chlordiazepoxide (CDP): a) intermittently, experiencing hypothermia and rotarod performance (RR) deficit after test doses (contingency); b) chronically, experiencing hypothermia and RR deficit after test doses; c) intermittently, RR preceding test doses and with protection against hypothermia afforded by exposure to heat lamps (nonexperienced, noncontingency); and d) chronically, RR preceding test doses and with protection against hypothermia."3.68Cellular and learned tolerances to chlordiazepoxide hypothermia and ataxia. ( MacKenzie-Taylor, DR; Rech, RH, 1993)
" The effects of two anaesthetics, sodium pentobarbital and urethane, and the effects of anaesthesia-associated hypothermia on acid-base status and blood gases were studied in rats without assisted ventilation."3.68Differential effects of hypothermia upon blood acid-base state and blood gases in sodium pentobarbital and urethane anaesthetised rats. ( Alfaro, V; Palacios, L, 1992)
"The development of behavioral tolerance to pentobarbital-induced hypothermia, as separable from cellular and metabolic tolerance, was established."3.68Cellular and learned tolerances for pentobarbital hypothermia. ( MacKenzie-Taylor, DR; Rech, RH, 1991)
" Their central nervous system actions based on spontaneous locomotor activity, antagonistic effect on reserpine-induced hypothermia, and antagonistic effect on pentobarbital anesthesia were evaluated and the structure-activity relationships are discussed."3.68Synthesis and central nervous system actions of thyrotropin-releasing hormone analogues containing a dihydroorotic acid moiety. ( Ishida, R; Matsumoto, K; Sugano, H; Suzuki, M; Yamamura, M, 1990)
"The in situ rat gut technique was used to study the effects of hypothermia on the intestinal absorption of a 1 mg/ml solution of sodium pentobarbital in 0."3.67Effects of hypothermia on drug absorption. ( Stavchansky, S; Tung, IL, 1987)
" In both ovariectomized rats and rats treated with estradiol and progesterone, pentobarbital caused a marked hypothermia and blocked LH hypersecretion."3.67Role of hypothermia in the pentobarbital-induced blockade of luteinizing hormone secretion in female rats. ( Katovich, MJ; Simpkins, JW, 1987)
"In this experiment we investigated inhibitory Pavlovian conditioning in the development of tolerance to pentobarbital-induced hypothermia."3.67Pavlovian inhibitory conditioning and tolerance to pentobarbital-induced hypothermia in rats. ( Hinson, RE; Siegel, S, 1986)
"Rats were given five separate pairings (sequential IP injections) of pentobarbital and lithium chloride, both hypothermia-inducing agents."3.66Attenuation of pentobarbital-elicited hypothermia in rats with a history of pentobarbital-LiCl pairings. ( Taukulis, HK, 1982)
"Hypothermia was induced in awake, anesthetized and brain ischemic-anesthetized rats."1.31Effect of hypothermia on brain multi-parametric activities in normoxic and partially ischemic rats. ( Etziony, R; Granot, E; Mayevsky, A; Sonn, J, 2002)
"When doxapram was given intraperitoneally 60 min."1.28Interaction of doxapram and pentobarbital in mice. ( Ishikawa, M; Ozaki, M; Sasaki, K; Suzuki, I; Takayanagi, Y, 1991)
" Fischer 344 rats were separated into multiple groups and underwent two dose-response evaluations."1.28Cerebral radioprotection by pentobarbital: dose-response characteristics and association with GABA agonist activity. ( Delaney, T; Friedman, R; Oldfield, EH; Olson, JJ; Orr, K, 1990)
"Halothane was most effective in producing anaesthesia in Monodelphis domestica."1.27An evaluation of three anaesthetic regimes in the gray short-tailed opossum (Monodelphis domestica). ( Bowman, TA; Drozdowicz, CK; Keller, LS; Lang, CM; Rice, L, 1988)
"Pentobarbital hypnosis was also antagonized by TRH in mice rendered tolerant to PB by implantation of a pellet (each containing 75 mg of free acid form of the drug) for two days."1.26The effects of thyrotropin releasing hormone on pentobarbital tolerance. ( Bhargava, HN, 1981)
"3 A second cannabis extract (II) with a different ratio of cannabinoids (also administered in dosage equivalent to 10 mg Delta(9)-THC/kg) failed to affect pentobarbitone anaesthesia in mice."1.25Interaction of cannabis and general anaesthetic agents in mice. ( Chesher, GB; Jackson, DM; Starmer, GA, 1974)

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-199038 (61.29)18.7374
1990's15 (24.19)18.2507
2000's7 (11.29)29.6817
2010's2 (3.23)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Slater, CA1
Jackson, A1
Muldoon, PP1
Dawson, A1
O'Brien, M1
Soll, LG1
Abdullah, R1
Carroll, FI1
Tapper, AR1
Miles, MF1
Banks, ML1
Bettinger, JC1
Damaj, IM1
Miyazawa, S1
Shimizu, Y1
Shiina, T1
Hirayama, H1
Morita, H1
Takewaki, T1
Wang, LE1
Zhang, XQ1
Yin, YQ1
Zhang, YH1
LESSIN, AW1
PARKES, MW1
CLIFFORD, DH1
BROOM, B1
LOEFGREN, L1
GLEES, P1
BLUMER, WF1
COLE, J1
MASSOPUST, LC1
ALBIN, MS1
BARNES, HW1
MEDER, R1
KRETCHMER, HW1
OROSZ, E1
TANABE, K1
TAKAORI, S1
SVANES, K2
CASTBERG, T2
SAURBREY, J2
SIVERTSEN, U2
WANDALL, HH2
SWAN, H1
MILLER, JA1
MILLER, FS1
Muhuri, D1
Karmakar, S1
Dasgupta, SC1
Nagchaudhuri, AK1
Gomes, A1
Kiyatkin, EA1
Brown, PL1
Boyce-Rustay, JM1
Cameron, HA1
Holmes, A1
Buchel, L2
Tanguy, O1
Kalivas, PW1
Horita, A1
Luttinger, D1
Nemeroff, CB1
Mason, GA1
Frye, GD1
Breese, GR1
Prange, AJ1
Taukulis, HK1
Bhargava, HN1
Koren, G1
Chin, TW1
Ali, SF1
Newport, RR1
Holson, W1
Slikker, W1
Bowyer, JF1
Nemoto, EM1
Klementavicius, R1
Yonas, H1
MacKenzie-Taylor, DR2
Rech, RH2
Strutton, PH1
Coen, CW1
Bansinath, M1
Nivarthi, RN1
Turndorf, H1
Dines, KC1
Mizisin, AP1
Jorge, MC1
Nunag, KD1
Kalichman, MW1
Wong, JP1
Saravolac, EG1
Clement, JG1
Nagata, LP1
Kim, SY1
Raikoff, K1
Wülfert, E1
Hanin, I1
Corral, C1
Lissavetzky, J1
Manzanares, I1
Darias, V1
Expósito-Orta, MA1
Martïn Conde, JA1
Sánchez-Mateo, CC1
Torbati, D1
Camacho, MT1
Raszynski, A1
Sussmane, JB1
Totapally, BR1
Hultquist, K1
Wolfsdorf, J1
Sonn, J1
Granot, E1
Etziony, R1
Mayevsky, A1
Crabbe, JC1
Metten, P1
Gallaher, EJ1
Belknap, JK1
Alfaro, V1
Palacios, L1
French, TA1
Weiner, N1
Ishikawa, M1
Suzuki, I1
Ozaki, M1
Takayanagi, Y1
Sasaki, K1
Suzuki, M1
Sugano, H1
Matsumoto, K1
Yamamura, M1
Ishida, R1
Olson, JJ1
Friedman, R1
Orr, K1
Delaney, T1
Oldfield, EH1
Keller, LS1
Drozdowicz, CK1
Rice, L1
Bowman, TA1
Lang, CM1
Stavchansky, S1
Tung, IL1
Hoffman, PL1
Tabakoff, B1
Szabó, G1
Suzdak, PD1
Paul, SM1
Simpkins, JW1
Katovich, MJ1
Hinson, RE1
Siegel, S1
Fell, RH1
Gunning, AJ1
Bardhan, KD1
Triger, DR1
Chesher, GB1
Jackson, DM1
Starmer, GA1
Ponessa, JT1
De Boer, B1
Day, EA1
Morgan, EB1
Baird, J1
Lang, WJ1
Gehres, LD1
Randall, CL1
Riccio, DC1
Vardaris, RM1
Singh, KP1
Bhandari, DS1
Andrews, PM1
Panuska, JA1
Felicetti, CL1
Joyce, RA1
Kalser, SC1
Kelly, MP1
Forbes, EB1
Randolph, MM1
Gill, EW1
Paton, WD1
Pertwee, RG1
Squires, RD1
Jacobson, FH1
Zingg, W1

Reviews

1 review available for pentobarbital and Hypothermia, Accidental

ArticleYear
Accidental hypothermia: report of a case following alcohol and barbiturate overdose.
    Anaesthesia and intensive care, 1974, Volume: 2, Issue:1

    Topics: Adult; Alcoholic Intoxication; Blood Pressure; Electric Countershock; Female; Humans; Hypothermia; I

1974

Other Studies

61 other studies available for pentobarbital and Hypothermia, Accidental

ArticleYear
Nicotine Enhances the Hypnotic and Hypothermic Effects of Alcohol in the Mouse.
    Alcoholism, clinical and experimental research, 2016, Volume: 40, Issue:1

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Azetidines; Body Temperature; Central Nervous Syst

2016
Central A1-receptor activation associated with onset of torpor protects the heart against low temperature in the Syrian hamster.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 295, Issue:3

    Topics: Acclimatization; Adenosine; Adenosine A1 Receptor Agonists; Animals; Cold Temperature; Cricetinae; E

2008
Augmentative effect of spinosin on pentobarbital-induced loss of righting reflex in mice associated with presynaptic 5-HT1A receptor.
    The Journal of pharmacy and pharmacology, 2012, Volume: 64, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Administration, Oral; Aminopyridines; Analysis of Variance;

2012
The relation between sedation and body temperature in the mouse.
    British journal of pharmacology and chemotherapy, 1957, Volume: 12, Issue:2

    Topics: Anesthesia; Animals; Body Temperature; Chlorpromazine; Hypnotics and Sedatives; Hypothermia; Mice; P

1957
Effect of preanesthetic medication with promazine and promethazine on pentobarbital anesthesia and subsequent hypothermia in the cat.
    Journal of the American Veterinary Medical Association, 1960, Aug-15, Volume: 137

    Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Animals; Cats; Hypothermia; Hypothermia, Induced; P

1960
EFFECTS OF AIR, OXYGEN AND 20 PER CENT CARBON DIOXIDE ON THE RABBIT DURING SURFACE COOLING DOWN TO CARDIAC ARREST.
    Nature, 1963, Sep-21, Volume: 199

    Topics: Air; Animals; Carbon Dioxide; Electrocardiography; Electroencephalography; Heart Arrest; Heart Arres

1963
REACTION OF THE ADRENAL CORTEX DURING CONTROLLED EXPERIMENTAL HYPOTHERMIA.
    Annales medicinae experimentalis et biologiae Fenniae, 1963, Volume: 41

    Topics: Adrenal Cortex; Adrenal Glands; Animals; Coloring Agents; Hypothermia; Hypothermia, Induced; Lipid M

1963
A STUDY OF MONKEYS SUBJECTED TO HYPOTHERMIA.
    Neurochirurgia, 1963, Volume: 6

    Topics: Anesthesia; Anesthesia, Intravenous; Animals; Behavior, Animal; Brain; Haplorhini; Hypothermia; Hypo

1963
CORTICAL AND SUBCORTICAL RESPONSES TO HYPOTHERMIA.
    Experimental neurology, 1964, Volume: 9

    Topics: Barbiturates; Blood Pressure; Brain; Cats; Cerebral Cortex; Electrophysiological Phenomena; Electrop

1964
[SIGNIFICANCE OF GENERAL ANESTHESIA IN NEUROSURGERY].
    Ideggyogyaszati szemle, 1964, Volume: 17

    Topics: Anesthesia; Anesthesia, Endotracheal; Anesthesia, General; Brain Neoplasms; Cerebral Angiography; Ce

1964
EFFECTS OF COOLING AND WARMING OF THE COMMON CAROTID ARTERIES ON THE BRAIN AND TYMPANIC MEMBRANE TEMPERATURES IN THE RABBIT.
    Japanese journal of pharmacology, 1964, Volume: 14

    Topics: Animals; Blood Pressure; Body Temperature; Body Temperature Regulation; Brain; Carotid Arteries; Car

1964
STUDIES IN HYPOTHERMIA. II. THE INFLUENCE OF DEEP HYPOTHERMIA ON THE FORMATION OF FLUID EXUDATE IN ACUTE INFLAMMATION IN MICE.
    Acta anaesthesiologica Scandinavica, 1964, Volume: 8

    Topics: Anesthesia; Anesthesia, Intravenous; Anesthesiology; Animals; Body Fluids; Capillary Permeability; E

1964
STUDIES IN HYPOTHERMIA. 3. THE INFLUENCE OF PROLONGED DEEP HYPOTHERMIA AND OF BARBITURATE ANAESTHESIA ON THE BLOOD LEUKOCYTES IN MICE.
    Acta anaesthesiologica Scandinavica, 1964, Volume: 8

    Topics: Anesthesia; Anesthesia, Intravenous; Animals; Barbiturates; Blood Cell Count; Eosinophils; Hypotherm

1964
EXTRACORPOREAL CIRCULATION WITH HYPOTHERMIA AND SYMPATHETIC BLOC.
    Acta chirurgica Scandinavica, 1964, Volume: 128

    Topics: Autonomic Nerve Block; Creatine; Creatinine; Dogs; Extracorporeal Circulation; Heart; Heart, Artific

1964
ACID-CITRATE-DEXTROSE (ACD) BLOOD IN EXTRACORPOREAL CIRCULATION. AN EXPERIMENTAL STUDY.
    Acta chirurgica Scandinavica, 1964, Volume: 128

    Topics: Blood Preservation; Calcium; Citrates; Citric Acid; Dogs; Extracorporeal Circulation; Glucose; Heart

1964
EXPERIMENTAL ACUTE HEMORRHAGE. THE RELATION OF BLOOD PRESSURE CHANGE TO PLASMA DILUTION.
    Archives of surgery (Chicago, Ill. : 1960), 1965, Volume: 91

    Topics: Animals; Blood Pressure; Blood Volume Determination; Dogs; Hemorrhage; Hypothermia; Iodine Isotopes;

1965
Factors in neonatal resistance to anoxia. III. Potentiation by narcosis of the effects of hypothermia in the newborn guinea pig.
    American journal of obstetrics and gynecology, 1962, Jul-01, Volume: 84

    Topics: Asphyxia Neonatorum; Chlorpromazine; Guinea Pigs; Humans; Hypothermia; Hypothermia, Induced; Hypoxia

1962
Pharmacological studies on the venomous spotted butterfish (Scatophagus argus Linn) sting extract on experimental animals.
    Indian journal of experimental biology, 2004, Volume: 42, Issue:5

    Topics: Animals; Behavior, Animal; Blood Pressure; Body Temperature; Capillaries; Cats; Chickens; Edema; Fem

2004
Brain and body temperature homeostasis during sodium pentobarbital anesthesia with and without body warming in rats.
    Physiology & behavior, 2005, Mar-31, Volume: 84, Issue:4

    Topics: Analysis of Variance; Anesthesia; Animals; Body Temperature Regulation; Brain; Heating; Hippocampus;

2005
Chronic swim stress alters sensitivity to acute behavioral effects of ethanol in mice.
    Physiology & behavior, 2007, May-16, Volume: 91, Issue:1

    Topics: Alcohol Drinking; Animals; Ataxia; Behavior, Animal; Body Temperature; Central Nervous System Depres

2007
[Influence of environmental temperature on the duration of experimental sleep and cerebral metabolism of hypnotics in rodents].
    Archives des sciences physiologiques, 1967, Volume: 21, Issue:4

    Topics: Alcohols; Animals; Brain; Chloral Hydrate; Hexobarbital; Hypothermia; Mice; Pentobarbital; Rats; Sle

1967
Thyrotropin-releasing hormone: neurogenesis of actions in the pentobarbital narcotized rat.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 212, Issue:2

    Topics: Animals; Behavior, Animal; Brain; Central Nervous System Stimulants; Diffusion; Hypothermia; Male; M

1980
Enhancement of ethanol-induced sedation and hypothermia by centrally administered neurotensin, beta-endorphin and bombesin.
    Neuropharmacology, 1981, Volume: 20, Issue:3

    Topics: Animals; beta-Endorphin; Bombesin; Drug Synergism; Endorphins; Ethanol; Hypnotics and Sedatives; Hyp

1981
Attenuation of pentobarbital-elicited hypothermia in rats with a history of pentobarbital-LiCl pairings.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:4

    Topics: Animals; Body Temperature; Body Temperature Regulation; Chlorides; Hypothermia; Lithium; Lithium Chl

1982
The effects of thyrotropin releasing hormone on pentobarbital tolerance.
    European journal of pharmacology, 1981, Jun-10, Volume: 72, Issue:1

    Topics: Animals; Body Temperature; Drug Tolerance; Hypothermia; Male; Mice; Pentobarbital; Sleep; Thyrotropi

1981
Hypothermia, alkalosis, and barbiturate clearance.
    The Journal of pediatrics, 1983, Volume: 102, Issue:4

    Topics: Alkalosis; Humans; Hypothermia; Intracranial Pressure; Pentobarbital

1983
Low environmental temperatures or pharmacologic agents that produce hyperthermia decrease methamphetamine neurotoxicity in mice.
    Annals of the New York Academy of Sciences, 1995, Sep-15, Volume: 765

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cold Temperature; Corpus Striatum; Dizocilpine Maleate; Dop

1995
Effects of hypothermia on cerebral metabolic rate for oxygen.
    Journal of neurosurgical anesthesiology, 1994, Volume: 6, Issue:3

    Topics: Animals; Barbiturates; Brain; Dogs; Energy Metabolism; Haplorhini; Humans; Hypothermia; Norepinephri

1994
Cellular and learned tolerances to chlordiazepoxide hypothermia and ataxia.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 44, Issue:3

    Topics: Animals; Ataxia; Body Temperature; Chlordiazepoxide; Drug Tolerance; Hypothermia; Learning; Male; Pe

1993
Sodium pentobarbitone and the suppression of luteinizing hormone pulses in the female rat: the role of hypothermia.
    Journal of neuroendocrinology, 1996, Volume: 8, Issue:12

    Topics: Adjuvants, Anesthesia; Animals; Body Temperature Regulation; Female; Hypothermia; Luteinizing Hormon

1996
Role of nitric oxide-mediated signal transduction in hypothermia induced by intravenous anesthetics.
    Annals of the New York Academy of Sciences, 1997, Mar-15, Volume: 813

    Topics: Anesthetics, Intravenous; Animals; Cerebellum; Cyclic GMP; Hypothermia; Ketamine; Mice; Nitric Oxide

1997
Effects of body and hindlimb temperature on laser Doppler blood flow and vascular conductance in rat sciatic nerve and skeletal muscle.
    Journal of the neurological sciences, 1997, May-01, Volume: 148, Issue:1

    Topics: Adjuvants, Anesthesia; Animals; Body Temperature; Female; Hindlimb; Hypothermia; Laser-Doppler Flowm

1997
Development of a murine hypothermia model for study of respiratory tract influenza virus infection.
    Laboratory animal science, 1997, Volume: 47, Issue:2

    Topics: Animals; Body Temperature; Disease Models, Animal; Female; Hypothermia; Lethal Dose 50; Mice; Mice,

1997
Bradycardia induced by mivazerol, a selective alpha 2-adrenoceptor agonist, is amplified during mild hypothermia in the pentobarbital-anesthetized rat.
    Cardiovascular drugs and therapy, 1997, Volume: 11, Issue:6

    Topics: Adjuvants, Anesthesia; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Anesthesi

1997
Synthesis and preliminary pharmacological evaluation of thiophene analogues of viloxazine as potential antidepressant drugs.
    Bioorganic & medicinal chemistry, 1999, Volume: 7, Issue:7

    Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Apomorphine; Blepharoptosis; Dose-Response Rela

1999
Effect of hypothermia on ventilation in anesthetized, spontaneously breathing rats: theoretical implications for mechanical ventilation.
    Intensive care medicine, 2000, Volume: 26, Issue:5

    Topics: Adjuvants, Anesthesia; Analysis of Variance; Anesthesia; Animals; Female; Hemodynamics; Hypothermia;

2000
Effect of hypothermia on brain multi-parametric activities in normoxic and partially ischemic rats.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2002, Volume: 132, Issue:1

    Topics: Animals; Brain; Brain Ischemia; Cerebrovascular Circulation; Hypothermia; Male; Mitochondria; NAD; O

2002
Genetic determinants of sensitivity to pentobarbital in inbred mice.
    Psychopharmacology, 2002, Volume: 161, Issue:4

    Topics: Animals; Brain; Dose-Response Relationship, Drug; Genetics, Behavioral; Hypothermia; Male; Mice; Mic

2002
Differential effects of hypothermia upon blood acid-base state and blood gases in sodium pentobarbital and urethane anaesthetised rats.
    General pharmacology, 1992, Volume: 23, Issue:4

    Topics: Acid-Base Equilibrium; Acidosis, Lactic; Anesthesia; Animals; Blood Gas Analysis; Body Temperature;

1992
Serotoninergic involvement in ethanol-induced alterations of thermoregulation in long-sleep and short-sleep mice.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:2

    Topics: Animals; Body Temperature Regulation; Brain; Ethanol; Female; Hypothalamus; Hypothermia; Indoles; Ma

1991
Cellular and learned tolerances for pentobarbital hypothermia.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 39, Issue:2

    Topics: Animals; Brain; Drug Tolerance; Hypothermia; Learning; Male; Pentobarbital; Rats; Rats, Inbred Strai

1991
Interaction of doxapram and pentobarbital in mice.
    Pharmacology & toxicology, 1991, Volume: 69, Issue:4

    Topics: Animals; Blood Proteins; Brain; Cytochrome P-450 Enzyme System; Doxapram; Drug Interactions; Guinea

1991
Synthesis and central nervous system actions of thyrotropin-releasing hormone analogues containing a dihydroorotic acid moiety.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:8

    Topics: Anesthesia; Central Nervous System; Chemical Phenomena; Chemistry; Hypothermia; Molecular Structure;

1990
Cerebral radioprotection by pentobarbital: dose-response characteristics and association with GABA agonist activity.
    Journal of neurosurgery, 1990, Volume: 72, Issue:5

    Topics: Anesthesia, General; Animals; Brain; Diazepam; Dose-Response Relationship, Drug; Dose-Response Relat

1990
An evaluation of three anaesthetic regimes in the gray short-tailed opossum (Monodelphis domestica).
    Laboratory animals, 1988, Volume: 22, Issue:3

    Topics: Anesthesia; Animals; Halothane; Hypothermia; Ketamine; Opossums; Pentobarbital; Xylazine

1988
Effects of hypothermia on drug absorption.
    Pharmaceutical research, 1987, Volume: 4, Issue:3

    Topics: Animals; Body Temperature; Hypothermia; Intestinal Absorption; Intestinal Mucosa; Male; Pentobarbita

1987
Effect of an imidazobenzodiazepine, Ro15-4513, on the incoordination and hypothermia produced by ethanol and pentobarbital.
    Life sciences, 1987, Aug-03, Volume: 41, Issue:5

    Topics: Animals; Azides; Benzodiazepines; Body Temperature Regulation; Ethanol; Hypothermia; Kinetics; Male;

1987
Role of hypothermia in the pentobarbital-induced blockade of luteinizing hormone secretion in female rats.
    Neuroendocrinology, 1987, Volume: 46, Issue:3

    Topics: Animals; Estradiol; Female; Hypothermia; Luteinizing Hormone; Ovariectomy; Ovary; Pentobarbital; Pro

1987
Pavlovian inhibitory conditioning and tolerance to pentobarbital-induced hypothermia in rats.
    Journal of experimental psychology. Animal behavior processes, 1986, Volume: 12, Issue:4

    Topics: Animals; Conditioning, Classical; Drug Tolerance; Hypothermia; Inhibition, Psychological; Male; Pent

1986
Severe hypothermia as a result of barbiturate overdose complicated by cardiac arrest.
    Lancet (London, England), 1968, Feb-24, Volume: 1, Issue:7539

    Topics: Adult; Anuria; Electric Countershock; Electrocardiography; Extracorporeal Circulation; Female; Heart

1968
Interaction of cannabis and general anaesthetic agents in mice.
    British journal of pharmacology, 1974, Volume: 50, Issue:4

    Topics: Anesthesia, General; Animals; Cannabis; Desipramine; Dronabinol; Drug Synergism; Ethyl Ethers; Fencl

1974
The effect of reserpine and syrosingopine upon pentobarbital depression.
    Archives internationales de pharmacodynamie et de therapie, 1966, Volume: 164, Issue:1

    Topics: Animals; Blood Pressure; Body Temperature; Central Nervous System; Drug Synergism; Hypotension; Hypo

1966
The effects of monoamine oxidase inhibitors on hypothermia produced in rats and rabbits by anaesthetics.
    European journal of pharmacology, 1973, Volume: 22, Issue:1

    Topics: Anesthesia, Intravenous; Anesthetics; Animals; Body Temperature; Female; Halothane; Hypothermia; Inj

1973
Attenuation of hypothermic retrograde amnesia produced by pharmacologic blockage of brain seizures.
    Physiology & behavior, 1973, Volume: 10, Issue:6

    Topics: Amnesia; Amygdala; Animals; Avoidance Learning; Body Temperature; Cold Temperature; Electroencephalo

1973
Experimental study on neuropharmacological actions of some indole derivatives.
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:7

    Topics: Amines; Analgesics; Animals; Anticonvulsants; Catatonia; Central Nervous System; Conditioning, Psych

1973
Cardiovascular responses of the unanesthetized and unrestrained hypothermic rat.
    Journal of applied physiology, 1969, Volume: 27, Issue:4

    Topics: Animals; Blood Pressure; Cardiac Output; Cerebrovascular Circulation; Hypothermia; Iodine Isotopes;

1969
Drug metabolism in hypothermia. Uptake, metabolism and biliary excretion of pentobarbital-2-C14 by the isolated, perfused rat liver in hypothermia and euthermia.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 170, Issue:1

    Topics: Animals; Atropine; Bile; Carbon Isotopes; Hypothermia; Liver; Male; Pentobarbital; Perfusion; Procai

1969
Preliminary experiments on the chemistry and pharmacology of cannabis.
    Nature, 1970, Oct-10, Volume: 228, Issue:5267

    Topics: Acetylcholine; Adipose Tissue; Analgesia; Animals; Benzopyrans; Body Temperature; Cannabis; Cataleps

1970
Chronic deficits of temperature regulation produced in cats by preoptic lesions.
    The American journal of physiology, 1968, Volume: 214, Issue:3

    Topics: Animals; Body Temperature Regulation; Cats; Cold Temperature; Colon; Female; Hot Temperature; Hypoth

1968
Fast and slow rewarming after acute and prolonged hypothermia in rabbits.
    The Journal of trauma, 1969, Volume: 9, Issue:3

    Topics: Acute Disease; Anesthesia; Animals; Body Temperature; Chloralose; Chronic Disease; Heating; Hypnosis

1969
[Contribution to the study of pentobarbital metabolism in rodents as a function of sex].
    Archives des sciences physiologiques, 1969, Volume: 23, Issue:1

    Topics: Animals; Brain; Female; Hypothermia; Male; Mice; Pentobarbital; Rats; Sex Factors; Sleep; Time Facto

1969