pentobarbital has been researched along with Hypertrophy in 2 studies
Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.
Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Threshold dosages of the photoisomers of cyclodiene insecticides, namely photochlordane, photodieldrin, and photoheptachlor, for the induction of hepatic microsomal cytochrome P450 (P450) and liver hypertrophy in male rats were at least one-quarter of those reported for corresponding parent cyclodienes." | 3.70 | Effects of photoisomers of cyclodiene insecticides on liver and microsomal cytochrome P450 in rats. ( Jovanovich, LV; Khan, MA; Martin, LT; Podowski, AA; Qadri, SY, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khan, MA | 1 |
| Jovanovich, LV | 1 |
| Martin, LT | 1 |
| Qadri, SY | 1 |
| Podowski, AA | 1 |
| Capron, JP | 1 |
| Dumont, M | 1 |
| Feldmann, G | 1 |
| Erlinger, S | 1 |
2 other studies available for pentobarbital and Hypertrophy
| Article | Year |
|---|---|
Effects of photoisomers of cyclodiene insecticides on liver and microsomal cytochrome P450 in rats.
Topics: Aniline Hydroxylase; Animals; Body Weight; Chlordan; Cytochrome P-450 Enzyme System; Dieldrin; Enzym | 1998 |
Barbiturate-induced choleresis: possible independence from microsomal enzyme induction.
Topics: Animals; Barbital; Barbiturates; Bile; Bile Acids and Salts; Cytochrome P-450 Enzyme System; Endopla | 1977 |