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pentobarbital and Hepatic Encephalopathy

pentobarbital has been researched along with Hepatic Encephalopathy in 4 studies

Pentobarbital: A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA Drug Evaluations Annual, 1994, p236)
pentobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and sec-pentyl groups.

Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)

Research Excerpts

ExcerptRelevanceReference
" The development of hepatic encephalopathy due to galactosamine-induced fulminant hepatic failure was consistently associated with a series of distinctive changes in the visual evoked potential waveform."3.67Visual evoked potentials in a rabbit model of hepatic encephalopathy. I. Sequential changes and comparisons with drug-induced comas. ( Brody, LE; Jacobs, R; Jones, EA; Pappas, SC; Schafer, DF, 1984)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
WARREN, KS1
SCHENKER, S1
Popken, RJ1
Kropveld, D1
Oosting, J1
Chamuleau, RA1
Schafer, DF1
Pappas, SC1
Brody, LE1
Jacobs, R1
Jones, EA1
Tsang, D1
Lal, S1
Sourkes, TL1
Ford, RM1
Aronoff, A1

Other Studies

4 other studies available for pentobarbital and Hepatic Encephalopathy

ArticleYear
DRUGS RELATED TO THE EXACERBATION OR AMELIORATION OF HEPATIC COMA AND THEIR EFFECTS ON AMMONIA TOXICITY.
    Clinical science, 1963, Volume: 25

    Topics: Acetazolamide; Ammonia; Ammonium Chloride; Arginine; Chlorothiazide; Cortisone; Formaldehyde; Glutam

1963
Quantitative analysis of EEG power spectra in experimental hepatic encephalopathy.
    Neuropsychobiology, 1983, Volume: 9, Issue:4

    Topics: Animals; Diazepam; Electroencephalography; Ether; Galactosamine; Hepatic Encephalopathy; Male; Pento

1983
Visual evoked potentials in a rabbit model of hepatic encephalopathy. I. Sequential changes and comparisons with drug-induced comas.
    Gastroenterology, 1984, Volume: 86, Issue:3

    Topics: Animals; Diazepam; Disease Models, Animal; Electrodes; Electroencephalography; Evoked Potentials, Vi

1984
Studies on cyclic AMP in different compartments of cerebrospinal fluid.
    Journal of neurology, neurosurgery, and psychiatry, 1976, Volume: 39, Issue:12

    Topics: Adult; Aged; Cerebral Ventricles; Cisterna Magna; Cyclic AMP; Diazepam; Female; Hepatic Encephalopat

1976